desipramine has been researched along with yohimbine in 102 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (55.88) | 18.7374 |
| 1990's | 27 (26.47) | 18.2507 |
| 2000's | 11 (10.78) | 29.6817 |
| 2010's | 7 (6.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Guare, JP; Halczenko, W; Huff, JR; Hunt, CA; Lotti, VJ; Randall, WC; Saari, WS; Yarbrough, GG | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R | 1 |
| Doxey, JC; Everitt, J; Metcalf, G | 1 |
| de Langen, CD; Mulder, AH; van der Lugt, JC; Wemer, J | 1 |
| de Langen, CD; de Regt, V; Hogenboom, F; Mulder, AH | 1 |
| Di Bona, G; Finberg, JP; Lavian, G | 1 |
| Männistö, PT; Törnwall, M | 1 |
| Malinowska, B; Molderings, G; Schlicker, E; Schneider, D | 1 |
| Grealy, M; O'Donnell, JM | 1 |
| Bähring, A; Brunn, G; Elsner, M; Racké, K; Wessler, I | 1 |
| Cai, B; Matsumoto, K; Ohta, H; Satoh, T; Watanabe, H | 1 |
| Cox, HS; Eisenhofer, G; Esler, MD | 1 |
| Gerlich, M; Graefe, KH; Halbrügge, T; Ludwig, J | 1 |
| Chang, PC; Goldstein, DS; Grossman, E; Kopin, IJ; Szemeredi, K | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Errchidi, S; Hilaire, G; Monteau, R | 1 |
| Forfar, JC; Riemersma, RA; Russell, DC | 1 |
| Campbell, IC; Ellison, DW | 1 |
| Limberger, N; Mayer, A; Singer, EA; Starke, K; Valenta, B; Zier, G | 1 |
| Carvalho, F; Gonçalves, J; Guimarães, S | 1 |
| Dawson, R; Nagahama, S; Oparil, S | 1 |
| Iuvone, PM; Johnson, RD; Minneman, KP | 1 |
| Swann, AC | 3 |
| Dodt, C; Gross, G; Hanft, G | 1 |
| Bradley, L; Doggrell, SA | 2 |
| Rafuse, PE; Smith, PA | 1 |
| Asakura, M; Tsukamoto, T | 1 |
| Ehrenström, F; Johansson, P | 1 |
| Moulds, RF; Stevens, MJ | 1 |
| Convery, ME; Domino, EF; Selden, EM; Stites, MM | 1 |
| Charney, DS; Heninger, GR; Price, LH | 1 |
| Blaschke, D; Laakmann, G; Meissner, R; Schoen, HW; Weiss, A; Wittmann, M; Zygan, K | 1 |
| Laakmann, G; Meissner, R; Schoen, HW; Weiss, A; Wittmann, M; Zygan, K | 1 |
| Laakmann, G; Meissner, R; Mueller, OA; Schoen, HW; Stalla, GK; Weiss, A; Wittmann, M; Zygan, K | 1 |
| Campbell, IC; McWilliam, JR | 1 |
| Heninger, GR; Price, LH | 1 |
| Abercrombie, ED; Keller, RW; Zigmond, MJ | 1 |
| Eisenhofer, G; Folio, CJ; Goldstein, DS; Keiser, HR; Kopin, IJ; Stull, R | 1 |
| Boudreau, G; de Champlain, J; Lamontagne, D; Nadeau, R; Yamaguchi, N | 1 |
| Prosdocimi, M; Tessari, F | 1 |
| Goldstein, DS; Keiser, HR; Kopin, IJ; Stull, R; Zimlichman, R | 1 |
| Cash, R; Dennis, T; Javoy-Agid, F; L'Heureux, R; Raisman, R; Scatton, B | 1 |
| Godse, DD; Li, PP; Warsh, JJ | 1 |
| Godse, DD; Guttman, M; Li, PP; Warsh, JJ | 1 |
| Green, KL | 1 |
| Campbell, IC; McKernan, RM; Smokcum, RW; Stephenson, JD; Weeramanthri, TB | 1 |
| Wakade, AR; Wakade, TD | 1 |
| Hedler, L; Majewski, H; Starke, K | 1 |
| Ennis, C; Lattimer, N | 1 |
| Angus, JA; Korner, PI | 1 |
| Johnson, RW; Reisine, T; Spotnitz, S; Ursillo, R; Wiech, N; Yamamura, HI | 1 |
| Ursillo, RC; Wiech, NL | 1 |
| Robie, NW | 1 |
| Chang, RS; Kling, P; Lotti, VJ | 1 |
| García-Sevilla, JA; Hollingsworth, PJ; Smnith, CB | 1 |
| Galzin, AM; Langer, SZ; Moret, C | 1 |
| Cloutier, G; Cubeddu, LX; Grippo, R; Gross, K; Harden, TK; Knowlton, G; Lerea, L; Shakarjian, M; Stat, M; Tanner, L | 1 |
| Dart, AM; Dietz, R; Kübler, W; Mayer, E; Schömig, A | 1 |
| Maura, G; Pittaluga, A; Raiteri, M; Ricchetti, A | 1 |
| Kitada, Y; Kosasa, T; Miyauchi, T; Satoh, S | 1 |
| Mogilnicka, E | 1 |
| Hieble, JP; McCafferty, JP; Pendleton, RG; Roesler, JM | 1 |
| Köster, G | 1 |
| Starke, K; Stoffel, D; von Kügelgen, I | 1 |
| Ordway, GA | 1 |
| Shores, MM; Szot, P; Veith, RC | 1 |
| Asakura, W; Matsumoto, K; Ohta, H; Watanabe, H | 1 |
| Kulkarni, SK; Sharma, A | 2 |
| Brun, P; Buda, M; Gonon, F; Suaud-Chagny, MF | 1 |
| Kurz, K; Starke, K; von Kügelgen, I | 1 |
| Dailey, JW; Jobe, PC; Yan, QS | 2 |
| Palij, P; Stamford, JA | 1 |
| Kimura, T; Koganei, H; Satoh, S; Takeuchi, A | 1 |
| Gergen, KA; Kastin, AJ; Paul, D; Zadina, JE | 1 |
| de la Lande, IS; Ivar, PM; Marino, V; Parker, DA | 1 |
| de la Lande, IS; Hennian, E; Marino, V; Parker, DA | 1 |
| de la Lande, IS; Krishna, M; Marino, V; Narayanan, A; Parker, DA | 1 |
| Ferris, CF; King, JA; Messenger, T | 1 |
| HALLIWELL, G; QUINTON, RM; WILLIAMS, FE | 1 |
| Giraldo, J; Jimenez-Altayo, F; McGrath, JC; Vila, E | 1 |
| Dendorfer, A; Dominiak, P; Raasch, W; Ziegler, A | 1 |
| Barrera, G; Burke, TF; Garcia, AS; Hensler, JG; Ma, S; Morilak, DA | 1 |
| Ignatowski, TA; Reynolds, JL; Spengler, RN; Sud, R | 1 |
| Aksu, F; Belzung, C; Yalcin, I | 1 |
| Rosenzweig-Lipson, S; Schechter, LE; Sukoff Rizzo, SJ | 1 |
| Barrot, M; Doridot, S; Freund-Mercier, MJ; Hein, L; Petit-Demoulière, N; Tessier, LH; Yalcin, I | 1 |
| Kile, BM; Park, J; Wightman, RM | 1 |
| García-Bueno, B; Hinojosa, AE; Leza, JC; Madrigal, JL | 1 |
| Ben-Shachar, D; Karry, R; Klein, E; Lucki, A | 1 |
| Angus, JA; Rajasekaran, P; Wright, CE | 1 |
| Akiyama, T; Fukumitsu, M; Kamiya, A; Kawada, T; Shimizu, S; Sugimachi, M | 1 |
1 review(s) available for desipramine and yohimbine
| Article | Year |
|---|---|
[Antidepressant drugs and central monoaminergic receptors].
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Antipsychotic Agents; Binding Sites; Blood Platelets; Brain; Brain Chemistry; Cats; Clonidine; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Mianserin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Yohimbine | 1985 |
2 trial(s) available for desipramine and yohimbine
| Article | Year |
|---|---|
Desipramine-yohimbine combination treatment of refractory depression. Implications for the beta-adrenergic receptor hypothesis of antidepressant action.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Carbonate; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Receptors, Adrenergic, beta; Tranylcypromine; Yohimbine | 1986 |
Bupropion does not antagonize cardiovascular actions of clonidine in normal subjects and spontaneously hypertensive rats.
Topics: Adult; Animals; Blood Platelets; Blood Pressure; Bupropion; Clonidine; Desipramine; Heart Rate; Humans; Imipramine; In Vitro Techniques; Male; Propiophenones; Rats; Rats, Inbred Strains; Tritium; Yohimbine | 1984 |
99 other study(ies) available for desipramine and yohimbine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Adrenoceptor and tetrabenazine antagonism activities of some pyridinyltetrahydropyridines.
Topics: Animals; Blepharoptosis; Cerebral Cortex; Clonidine; Male; Methoxamine; Mice; Pyridines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Tetrabenazine | 1984 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.
Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface | 2014 |
Mianserin--an analysis of its peripheral autonomic actions.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Dibenzazepines; Electric Stimulation; Male; Mianserin; Norepinephrine; Phenoxybenzamine; Phentolamine; Rats; Tyramine; Yohimbine | 1978 |
On the capacity of presynaptic alpha receptors to modulate norepinephrine release from slices of rat neocortex and the affinity of some agonists and antagonists for these receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Desipramine; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Potassium; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1979 |
Alpha-receptor-mediated modulation of 3H-noradrenaline release from rat brain cortex synaptosomes.
Topics: Animals; Brain; Desipramine; In Vitro Techniques; Male; Norepinephrine; Oxymetazoline; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Synaptosomes; Time Factors; Yohimbine | 1978 |
Inhibition of sympathetic nerve activity by acute administration of the tricyclic antidepressant desipramine.
Topics: Animals; Blood Pressure; Desipramine; Drug Interactions; Heart Rate; Kidney; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Splanchnic Nerves; Sympathetic Nervous System; Yohimbine | 1991 |
Acute toxicity of three new selective COMT inhibitors in mice with special emphasis on interactions with drugs increasing catecholaminergic neurotransmission.
Topics: Amphetamine; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Clorgyline; Convulsants; Desipramine; Drug Interactions; Lethal Dose 50; Levodopa; Male; Mice; Motor Activity; Nitriles; Nomifensine; Pentanones; Selegiline; Synaptic Transmission; Yohimbine | 1991 |
Noradrenaline release in the rat vena cava is inhibited by gamma-aminobutyric acid via GABAB receptors but not affected by histamine.
Topics: Animals; Baclofen; Bicuculline; Corticosterone; Desipramine; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; In Vitro Techniques; Male; Muscimol; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vena Cava, Inferior; Yohimbine | 1991 |
Secretion of growth hormone elicited by intravenous desipramine in the conscious, unrestrained rat.
Topics: Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Growth Hormone; Hypothalamo-Hypophyseal System; Idazoxan; Injections, Intravenous; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Characterization of endogenous noradrenaline release from intact and epithelium-denuded rat isolated trachea.
Topics: Animals; Chromatography, High Pressure Liquid; Desipramine; Electric Stimulation; Electrochemistry; Epithelium; Female; In Vitro Techniques; Muscle Tonus; Muscle, Smooth; Norepinephrine; Oxotremorine; Potassium; Rats; Rats, Inbred Strains; Scopolamine; Tetrodotoxin; Trachea; Yohimbine | 1991 |
Desipramine enhances isolation-induced aggressive behavior in mice.
Topics: Aggression; Animals; Clonidine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Phentolamine; Prazosin; Social Isolation; Yohimbine | 1991 |
Noradrenaline reuptake and plasma dihydroxyphenylglycol during sustained changes in sympathetic activity in rabbits.
Topics: Animals; Blood Pressure; Brain; Clonidine; Desipramine; Heart Rate; Injections; Injections, Intravenous; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rabbits; Sympathetic Nervous System; Time Factors; Yohimbine | 1991 |
The importance of plasma 3,4-dihydroxyphenylglycol (DOPEG) in analyses of the sympathetic nervous system in vivo.
Topics: Adolescent; Adult; Aged; Animals; Clonidine; Desipramine; Female; Humans; Hypertension; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Rabbits; Sympathetic Nervous System; Synapses; Yohimbine | 1990 |
Fate of tritiated 6-fluorodopamine in rats: a false neurotransmitter for positron emission tomographic imaging of sympathetic innervation and function.
Topics: Animals; Desipramine; Dopamine; Exocytosis; Male; Nitroprusside; Normetanephrine; Rats; Reserpine; Sympathetic Nervous System; Tissue Distribution; Tomography, Emission-Computed; Tritium; Yohimbine | 1990 |
In vivo measurement of noradrenaline and 3,4-dihydroxyphenylethyleneglycol in the rat hypothalamus by microdialysis: effects of various drugs affecting noradrenaline metabolism.
Topics: Animals; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Dialysis; Electrochemistry; Extracellular Space; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Mianserin; Microchemistry; Norepinephrine; Rats; Rats, Inbred Strains; Tetrodotoxin; Yohimbine | 1990 |
Permanent release of noradrenaline modulates respiratory frequency in the newborn rat: an in vitro study.
Topics: Animals; Animals, Newborn; Brain Stem; Desipramine; In Vitro Techniques; Methyltyrosines; Norepinephrine; Pargyline; Piperoxan; Pons; Rats; Respiration; Spinal Cord; Time Factors; Yohimbine | 1990 |
Control of myocardial catecholamine release during acute ischemia.
Topics: Adenosine; Animals; Coronary Disease; Desipramine; Dogs; Electric Stimulation; Female; Heart; Male; Myocardium; Norepinephrine; Potassium; Synaptic Transmission; Yohimbine | 1985 |
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine | 1986 |
Estimation of pA2 values at presynaptic alpha 2-autoreceptors in rabbit and rat brain cortex in the absence of autoinhibition.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Kinetics; Male; Nordefrin; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1989 |
Uptake inhibitors do not change the effect of imidazoline alpha 2-adrenoceptor agonists on transmitter release evoked by single pulse stimulation in mouse vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Desipramine; Imidazoles; In Vitro Techniques; Male; Mice; Muscle, Smooth; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Normetanephrine; Phenethylamines; Vas Deferens; Yohimbine | 1989 |
Yohimbine-induced alterations of monoamine metabolism in the spontaneously hypertensive rat. I. The peripheral nervous system.
Topics: Adrenal Glands; Animals; Catecholamines; Desipramine; Heart Rate; Hypertension; Kidney; Male; Peripheral Nerves; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic; Species Specificity; Spleen; Yohimbine | 1987 |
Regulation of alpha-1 adrenergic receptor density and functional responsiveness in rat brain.
Topics: Animals; Benzylamines; Brain Chemistry; Cyclic AMP; Desipramine; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine; Yohimbine | 1987 |
Thyroid hormone and norepinephrine: effects on alpha-2, beta, and reuptake sites in cerebral cortex and heart.
Topics: Animals; Cerebral Cortex; Desipramine; Dihydroalprenolol; Heart; Hypothyroidism; Male; Methimazole; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Triiodothyronine; Yohimbine | 1988 |
Effect of chronic lithium administration on adrenoceptor binding and adrenoceptor regulation in rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Desipramine; Dihydroalprenolol; Hydroxydopamines; In Vitro Techniques; Injections, Intraventricular; Lithium; Male; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathectomy, Chemical; Yohimbine | 1988 |
Modification by desipramine of the effects of alpha-adrenoceptor antagonists on the contractile responses of the trisected rat vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Desipramine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine | 1985 |
Alpha 2-adrenergic hyperpolarization is not involved in slow synaptic inhibition in amphibian sympathetic ganglia.
Topics: Adrenergic alpha-Agonists; Animals; Cadmium; Desipramine; Epinephrine; Ganglia, Sympathetic; In Vitro Techniques; Membrane Potentials; Methacholine Chloride; Methacholine Compounds; Rana pipiens; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1986 |
Presynaptic alpha-adrenoceptor regulation of transmitter release in the conscious rat.
Topics: Adrenal Medulla; Animals; Atropine; Blood Pressure; Desipramine; Heart Rate; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stress, Physiological; Synapses; Yohimbine | 1988 |
Factors determining alpha-adrenoceptor-mediated responses of human digital arteries and metacarpal veins.
Topics: Desipramine; Dose-Response Relationship, Drug; Fingers; Humans; Hydrocortisone; Metacarpus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
(Na+,K+)-ATPase and noradrenergic regulation: effects of cardiac glycoside treatment and noradrenergic manipulations.
Topics: Animals; Benzylamines; Brain; Cardiac Glycosides; Clonidine; Desipramine; Digitoxin; Dihydroalprenolol; Kidney; Male; Methoxyhydroxyphenylglycol; Myocardium; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase; Yohimbine | 1985 |
Pharmacologic evidence that high dose chronic amitriptyline and desipramine down-regulate alpha 2-receptor-mediated hypothermia in the rat.
Topics: Amitriptyline; Animals; Body Temperature Regulation; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Half-Life; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Effect of receptor blockers (methysergide, propranolol, phentolamine, yohimbine and prazosin) on desimipramine-induced pituitary hormone stimulation in humans--I. Growth hormone.
Topics: Adolescent; Adult; Blood Glucose; Blood Pressure; Carrier Proteins; Desipramine; Drug Interactions; Growth Hormone; Humans; Male; Methysergide; Phentolamine; Pituitary Hormones; Prazosin; Propranolol; Receptors, Drug; Receptors, Neurotransmitter; Time Factors; Yohimbine | 1986 |
Effects of receptor blockers (methysergide, propranolol, phentolamine, yohimbine and prazosin) on desimipramine-induced pituitary hormone stimulation in humans--II. Prolactin.
Topics: Blood Glucose; Blood Pressure; Carrier Proteins; Desipramine; Drug Interactions; Heart Rate; Humans; Male; Methysergide; Phentolamine; Pituitary Hormones; Prazosin; Prolactin; Propranolol; Receptors, Drug; Receptors, Neurotransmitter; Time Factors; Yohimbine | 1986 |
Effects of receptor blockers (methysergide, propranolol, phentolamine, yohimbine and prazosin) on desimipramine-induced pituitary hormone stimulation in humans--III. Hypothalamo-pituitary-adrenocortical axis.
Topics: Blood Glucose; Blood Pressure; Carrier Proteins; Desipramine; Drug Interactions; Heart Rate; Humans; Hypothalamo-Hypophyseal System; Male; Methysergide; Phentolamine; Pituitary Hormones; Pituitary-Adrenal System; Prazosin; Propranolol; Receptors, Drug; Receptors, Neurotransmitter; Yohimbine | 1986 |
(Na+,K+)-ATPase and noradrenergic function: effects of chronic ethanol.
Topics: Animals; Benzylamines; Desipramine; Ethanol; Heart; Male; Neurotoxins; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Yohimbine | 1987 |
Effects of antidepressant drug treatments on alpha 2-adrenoceptor control of [3H]noradrenaline release from hypothalamic synaptosomes.
Topics: Animals; Antidepressive Agents; Clonidine; Clorgyline; Desipramine; Hypothalamus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1987 |
Can yohimbine be used to treat orthostatic hypotension associated with the use of desipramine and other antidepressants? What general and/or specific strategy do you recommend for treating orthostatic hypotension?
Topics: Desipramine; Humans; Hypotension, Orthostatic; Yohimbine | 1988 |
Characterization of hippocampal norepinephrine release as measured by microdialysis perfusion: pharmacological and behavioral studies.
Topics: Animals; Clonidine; Desipramine; Hippocampus; Male; Norepinephrine; Perfusion; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Yohimbine | 1988 |
Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans.
Topics: Administration, Oral; Adult; Body Fluids; Clonidine; Desipramine; Female; Glycols; Humans; Infusions, Intravenous; Intracellular Fluid; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Supination; Yohimbine | 1988 |
The course of panic attacks and agoraphobia.
Topics: Agoraphobia; Anxiety; Chronic Disease; Desipramine; Fear; Follow-Up Studies; Humans; Panic; Phobic Disorders; Yohimbine | 1988 |
Effects of yohimbine and desipramine on cardiac noradrenaline release and ventricular arrhythmias during acute coronary artery occlusion and reperfusion in anesthetized dogs.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Coronary Vessels; Desipramine; Dogs; Heart Rate; Lactates; Myocardium; Norepinephrine; Perfusion; Yohimbine | 1987 |
[Release of norepinephrine by cardiac sympathetic fibers in vitro. Pharmacologic modulation].
Topics: Adrenergic Fibers; Animals; Chromatography, High Pressure Liquid; Desipramine; Electric Stimulation; Heart Rate; In Vitro Techniques; Male; Myocardium; Norepinephrine; Propranolol; Rats; Yohimbine | 1987 |
Estimation of intrasynaptic norepinephrine concentrations in humans.
Topics: Adult; Blood Pressure; Desipramine; Dose-Response Relationship, Drug; Humans; Hypertension; Male; Middle Aged; Models, Biological; Neuroeffector Junction; Norepinephrine; Receptors, Adrenergic; Sympathetic Nervous System; Synapses; Trimethaphan; Yohimbine | 1986 |
Parkinson's disease and dementia: norepinephrine and dopamine in locus ceruleus.
Topics: Aged; Aged, 80 and over; Brain; Dementia; Desipramine; Dopamine; Homovanillic Acid; Humans; Locus Coeruleus; Methoxyhydroxyphenylglycol; Norepinephrine; Parkinson Disease; Yohimbine | 1987 |
Further characterization of brain 3,4-dihydroxyphenylethyleneglycol (DHPG) formation: dependence on noradrenergic activity and site of formation.
Topics: Animals; Brain; Desipramine; Electric Stimulation; Glycols; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains; Time Factors; Yohimbine | 1986 |
Studies on the utility of urinary 3,4-dihydroxyphenylethylene-glycol (DHPG) measurement.
Topics: Animals; Brain; Desipramine; Glycols; Guinea Pigs; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Yohimbine | 1985 |
Role of endogenous catecholamines in the anti-inflammatory activity of alpha-adrenoceptor blocking agents.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Capillary Permeability; Catecholamines; Cocaine; Desipramine; Dioxins; Epinephrine; Female; Methyltyrosines; Mice; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Phentolamine; Piperidines; Rats; Serum Albumin; Uterus; Yohimbine | 1974 |
Effect of desipramine, phenoxybenzamine and yohimbine on beta-adrenoceptors and cyclic AMP production in the rat brain.
Topics: Adenylyl Cyclases; Animals; Brain; Cyclic AMP; Desipramine; Dihydroalprenolol; Kinetics; Male; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Yohimbine | 1984 |
Release of noradrenaline by one pulse: modulation of such release by alpha-adrenoceptor antagonists and uptake blockers.
Topics: Adrenergic alpha-Antagonists; Animals; Desipramine; Electric Stimulation; Guinea Pigs; Heart; Male; Norepinephrine; Perfusion; Phenoxybenzamine; Phentolamine; Tetraethylammonium Compounds; Yohimbine | 1981 |
Evidence for a physiological role of presynaptic alpha-adrenoceptors: modulation of noradrenaline release in the pithed rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Electric Stimulation; Epinephrine; Female; Guanethidine; Heart Rate; Male; Nordefrin; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spinal Nerves; Yohimbine | 1983 |
Presynaptic agonist effect of phentolamine in the rabbit vas deferens and rat cerebral cortex.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Desipramine; In Vitro Techniques; Indoramin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Potassium; Rabbits; Rats; Rats, Inbred Strains; Vas Deferens; Yohimbine | 1984 |
Evidence against presynaptic alpha-adrenoreceptor modulation of cardiac sympathetic transmission.
Topics: Animals; Desipramine; Estradiol; Guinea Pigs; Heart; Heart Rate; Phenoxybenzamine; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Membranes; Synaptic Transmission; Yohimbine | 1980 |
Effects of desipramine and yohimbine on alpha 2- and beta-adrenoreceptor sensitivity.
Topics: Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Male; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors; Yohimbine | 1980 |
Acceleration of desipramine-induced decrease of rat corticocerebral beta-adrenergic receptors by yohimbine.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Desipramine; Drug Interactions; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Yohimbine | 1980 |
Evaluation of presynaptic alpha-receptor function in the canine renal vascular bed.
Topics: Animals; Cattle; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Antagonism; Epinephrine; Female; Kidney; Male; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasomotor System; Yohimbine | 1980 |
Pre- and postsynaptic adrenergic activation by norepinephrine reuptake inhibitors in the field-stimulated rat vas deferens.
Topics: Amitriptyline; Animals; Chlorpromazine; Cocaine; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Male; Norepinephrine; Prazosin; Protriptyline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1981 |
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Desipramine; Humans; In Vitro Techniques; Iprindole; Kinetics; Male; Mianserin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Effects of amitriptyline, desipramine and mianserin on noradrenergic transmission in the rat isolated right ventricle.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Electric Stimulation; Heart; In Vitro Techniques; Male; Mianserin; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Synaptic Transmission; Yohimbine | 1983 |
Evidence that exogenous but not endogenous norepinephrine activates the presynaptic alpha-2 adrenoceptors on serotonergic nerve endings in the rat hypothalamus.
Topics: Animals; Cocaine; Desipramine; Dioxins; Hypothalamus; Idazoxan; In Vitro Techniques; Male; Norepinephrine; Phentolamine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Yohimbine | 1984 |
Release of endogenous catecholamines in the ischemic myocardium of the rat. Part B: Effect of sympathetic nerve stimulation.
Topics: Animals; Coronary Disease; Desipramine; Extracellular Space; Myocardium; Norepinephrine; Rats; Sympathetic Nervous System; Yohimbine | 1984 |
Noradrenaline uptake inhibitors do not reduce the presynaptic action of clonidine on 3H-noradrenaline release in superfused synaptosomes.
Topics: Animals; Clonidine; Cocaine; Desipramine; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1984 |
Further studies on the suppressing effect of isoproterenol on the immobility-reducing action of desipramine in the forced swimming test.
Topics: Animals; Atenolol; Clonidine; Desipramine; Isoproterenol; Male; Motor Activity; Phenylephrine; Rats; Rats, Inbred Strains; Swimming; Yohimbine | 1983 |
The effects of acute and repeated treatment with salbutamol, a beta-adrenoceptor agonist, on clonidine-induced hypoactivity in rats.
Topics: Albuterol; Animals; Clonidine; Desipramine; Drug Interactions; Exploratory Behavior; Fluoxetine; Imipramine; Male; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
Mechanism for gastric antisecretory effects of desmethylimipramine in rats.
Topics: Animals; Blepharoptosis; Desipramine; Drug Interactions; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Rats; Rats, Inbred Strains; Yohimbine | 1981 |
Glial alpha 2-receptors probably inhibit the high-affinity uptake of noradrenaline into astrocytes in the rat brain in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Astrocytes; Brain; Desipramine; Feedback; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reserpine; Tropolone; Yohimbine | 1995 |
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine | 1995 |
Effect of noradrenergic lesions on subtypes of alpha 2-adrenoceptors in rat brain.
Topics: 5,7-Dihydroxytryptamine; Animals; Binding, Competitive; Cerebral Cortex; Desipramine; Guanosine Triphosphate; Male; Oxidopamine; Oxymetazoline; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine | 1995 |
Desipramine-induced increase in norepinephrine transporter mRNA is not mediated via alpha 2 receptors.
Topics: Animals; Carrier Proteins; Clonidine; Desipramine; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; RNA, Messenger; Symporters; Yohimbine | 1994 |
REM sleep deprivation potentiates the effects of imipramine and desipramine but not that of clomipramine in the forced swimming test.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Brain; Clomipramine; Desipramine; Imipramine; Male; Mice; Receptors, Adrenergic, alpha; Sleep Deprivation; Sleep, REM; Swimming; Yohimbine | 1993 |
Dopamine receptor mediated antidepressant action of B-HT 920 in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Azepines; Desipramine; Drug Interactions; Escape Reaction; Female; Haloperidol; Male; Mice; Motor Activity; Receptors, Dopamine; Reserpine; Sulpiride; Swimming; Yohimbine | 1994 |
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipramine; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Muscle Contraction; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reserpine; Sulpiride; Yohimbine | 1994 |
In vivo noradrenaline release evoked in the anteroventral thalamic nucleus by locus coeruleus activation: an electrochemical study.
Topics: Animals; Axons; Clonidine; Desipramine; Electric Stimulation; Electrochemistry; Evoked Potentials; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Norepinephrine; Oxidation-Reduction; Pargyline; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thalamic Nuclei; Yohimbine | 1993 |
Axon terminal P2-purinoceptors in feedback control of sympathetic transmitter release.
Topics: Adenosine Triphosphate; Animals; Axons; Desipramine; Drug Interactions; Feedback; GTP-Binding Proteins; Male; Mice; Nifedipine; Norepinephrine; Prazosin; Purinergic Antagonists; Receptors, Purinergic; Suramin; Sympathetic Nervous System; Triazines; Vas Deferens; Virulence Factors, Bordetella; Xanthines; Yohimbine | 1993 |
Thalamic deficiency in norepinephrine release detected via intracerebral microdialysis: a synaptic determinant of seizure predisposition in the genetically epilepsy-prone rat.
Topics: Analysis of Variance; Animals; Desipramine; Dialysis; Epilepsy; Female; Norepinephrine; Potassium Chloride; Rats; Thalamus; Time Factors; Yohimbine | 1993 |
Noradrenergic mechanisms for the anticonvulsant effects of desipramine and yohimbine in genetically epilepsy-prone rats: studies with microdialysis.
Topics: Animals; Anticonvulsants; Desipramine; Dialysis; Disease Susceptibility; Epilepsy; Female; Male; Micromanipulation; Norepinephrine; Rats; Serotonin; Synapses; Thalamus; Yohimbine | 1993 |
Rauwolscine potentiates the effect of desipramine on limbic noradrenaline efflux.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Desipramine; Drug Synergism; Electric Stimulation; Limbic System; Male; Norepinephrine; Rats; Rats, Wistar; Yohimbine | 1996 |
Effects of yohimbine and desipramine on adrenal catecholamine release in response to splanchnic nerve stimulation in anesthetized dogs.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Catecholamines; Desipramine; Dogs; Electric Stimulation; Female; Male; Splanchnic Nerves; Tyramine; Yohimbine | 1995 |
Intrathecal Tyr-W-MIF-1 produces potent, naloxone-reversible analgesia modulated by alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Desipramine; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Molecular Sequence Data; MSH Release-Inhibiting Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Norepinephrine; Receptors, Adrenergic, alpha-2; Yohimbine | 1996 |
Modulation by presynaptic beta-adrenoceptors of noradrenaline release from sympathetic nerves in human dental pulp.
Topics: Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Albuterol; Anti-Inflammatory Agents; Corticosterone; Dental Pulp; Desipramine; Electric Stimulation; Ethanolamines; Female; Humans; Isoproterenol; Male; Norepinephrine; Propranolol; Radiopharmaceuticals; Receptors, Adrenergic, beta; Receptors, Presynaptic; Sympathetic Nervous System; Sympatholytics; Sympathomimetics; Tritium; Yohimbine | 1998 |
Inhibitory effects of adrenaline on the release of noradrenaline from sympathetic nerves in human dental pulp.
Topics: Adolescent; Adrenergic Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Adult; Brimonidine Tartrate; Culture Techniques; Dental Pulp; Desipramine; Epinephrine; Humans; Norepinephrine; Quinoxalines; Radiopharmaceuticals; Receptors, Presynaptic; Sympathetic Nervous System; Tritium; Yohimbine | 1999 |
Failure of presynaptic purinoceptors to modulate noradrenaline release from sympathetic nerves in human dental pulp.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Culture Techniques; Dental Pulp; Desipramine; Humans; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Receptors, Presynaptic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Sympathomimetics; Tritium; Xanthines; Yohimbine | 2000 |
Seed finding in golden hamsters: a potential animal model for screening anxiolytic drugs.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Appetitive Behavior; Behavior, Animal; Buspirone; Chlordiazepoxide; Clozapine; Cricetinae; Desipramine; Drug Evaluation, Preclinical; Fasting; Fluoxetine; Injections, Intraperitoneal; Male; Mesocricetus; Models, Animal; Stress, Psychological; Yohimbine | 2002 |
A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.
Topics: Alcoholic Intoxication; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Autonomic Nervous System; Bradycardia; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Desipramine; Dogs; Epinephrine; Imipramine; Mice; Norepinephrine; Pharmacology; Promazine; Rats; Research; Reserpine; Sleep; Toxicology; Tranquilizing Agents; Vasomotor System; Yohimbine | 1964 |
Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle.
Topics: Animals; Blotting, Western; Carbachol; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; Male; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Phentolamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sacrococcygeal Region; Synaptic Transmission; Tyrosine 3-Monooxygenase; Yohimbine | 2003 |
Reduction of vascular noradrenaline sensitivity by AT1 antagonists depends on functional sympathetic innervation.
Topics: Adrenergic alpha-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Atropine; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Desipramine; Diastole; Dose-Response Relationship, Drug; Losartan; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reserpine; Sympathectomy, Chemical; Sympathetic Nervous System; Symporters; Tetrazoles; Tubocurarine; Yohimbine | 2004 |
Autoreceptor-mediated inhibition of norepinephrine release in rat medial prefrontal cortex is maintained after chronic desipramine treatment.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Autoreceptors; Clonidine; Desipramine; Dose-Response Relationship, Drug; Extracellular Fluid; Male; Microdialysis; Norepinephrine; Potassium; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time; Yohimbine | 2004 |
An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Blotting, Northern; Brimonidine Tartrate; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Freezing Reaction, Cataleptic; Gene Expression Regulation; In Vitro Techniques; Male; Neural Inhibition; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming; Time Factors; Tumor Necrosis Factor-alpha; Yohimbine | 2005 |
Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Chronic Disease; Desipramine; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Motor Activity; Pindolol; Stress, Physiological; Tramadol; Yohimbine | 2005 |
A novel approach for predicting antidepressant-induced sexual dysfunction in rats.
Topics: Animals; Antidepressive Agents; Bupropion; Desipramine; Disease Models, Animal; Dopamine Agonists; Fluoxetine; Long-Term Care; Male; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasodilator Agents; Yohimbine | 2008 |
Beta2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amines; Animals; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Cyclohexanols; Desipramine; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Transgenic; Morpholines; Pain; Pain Threshold; Propanolamines; Reboxetine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Sciatic Nerve; Venlafaxine Hydrochloride; Yohimbine | 2009 |
In vivo voltammetric monitoring of norepinephrine release in the rat ventral bed nucleus of the stria terminalis and anteroventral thalamic nucleus.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Anterior Thalamic Nuclei; Chromatography, High Pressure Liquid; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Electric Stimulation; Electrochemical Techniques; Lidocaine; Male; Microelectrodes; Neural Pathways; Norepinephrine; Piperazines; Raclopride; Rats; Rats, Sprague-Dawley; Septal Nuclei; Tissue Distribution; Yohimbine | 2009 |
Regulation of CCL2/MCP-1 production in astrocytes by desipramine and atomoxetine: involvement of α2 adrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; Animals; Astrocytes; Atomoxetine Hydrochloride; Cells, Cultured; Chemokine CCL2; Clonidine; Cyclic AMP; Desipramine; Isoproterenol; Norepinephrine; Propylamines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2011 |
Dexamethasone in the presence of desipramine enhances MAPK/ERK1/2 signaling possibly via its interference with β-arrestin.
Topics: Adrenergic alpha-2 Receptor Antagonists; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Arrestins; beta-Arrestins; Cell Line, Tumor; Desipramine; Dexamethasone; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Mifepristone; Mitogen-Activated Protein Kinase Kinases; Neuroblastoma; Norepinephrine; Signal Transduction; Time Factors; Ubiquitination; Yohimbine | 2014 |
Novel technique to determine the pK
Topics: Animals; Clonidine; Cystamine; Desipramine; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Male; Mesenteric Arteries; Mice; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 2017 |
Desipramine increases cardiac parasympathetic activity via α
Topics: Acetylcholine; Administration, Intravenous; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Blood Pressure; Cardiovascular Agents; Desipramine; Dose-Response Relationship, Drug; Heart; Heart Rate; Male; Myocardium; Parasympathomimetics; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Vagotomy; Vagus Nerve; Yohimbine | 2017 |