desipramine and trimipramine

desipramine has been researched along with trimipramine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19908 (26.67)18.7374
1990's5 (16.67)18.2507
2000's10 (33.33)29.6817
2010's6 (20.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Bleich, S; Kornhuber, J; Rupprecht, R; Terfloth, L; Wiltfang, J1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL1
Detaevernier, MR; Dryon, L; Massart, DL1
Musa, MN1
Hauser, K; Jones, RS; Olpe, HR1
Baumann, P; Cuendet, C; Eap, CB1
Bouthillier, A; de Montigny, C1
Joffe, RT; Richter, MA1
Jones, RS; Olpe, HR1
Caillé, G; Cournoyer, G; de Montigny, C; Langlois, R; Morissette, R1
Larrey, D; Michel, H; Pageaux, GP; Ramos, J; Remy, AJ; Ribstein, J1
Blier, P; De Montigny, C; Mongeau, R1
Bordier, C; Chen, KG; Durán, GE; Jaffrézou, JP; Laurent, G; Levade, T; Muller, C; Sikic, BI1
Bergeron, R; Blier, P; de Montigny, C1
Elie, R; Habimana, A; Hébert, C; Reader, TA1
Fernandez-Belda, F; Fortea, I; Plenge-Tellechea, F; Soler, F1
Aydin, S; Beis, R; Herekman-Demir, T; Oztürk, Y1
Jafari, MT; Saraji, M; Sherafatmand, H1
Sanghavi, BJ; Srivastava, AK1

Reviews

1 review(s) available for desipramine and trimipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for desipramine and trimipramine

ArticleYear
Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression. Correlations with the neurobiologic actions of tricyclic antidepressant drugs and lithium ion on the serotonin system.
    Archives of general psychiatry, 1983, Volume: 40, Issue:12

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Desipramine; Doxepin; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Lithium Carbonate; Male; Middle Aged; Neurons; Psychiatric Status Rating Scales; Serotonin; Trimipramine

1983

Other Studies

28 other study(ies) available for desipramine and trimipramine

ArticleYear
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship

1999
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Binding Sites; Computer Simulation; Databases, Factual; Models, Chemical; Models, Molecular; Molecular Structure; Molecular Weight; Psychotropic Drugs; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
    RSC medicinal chemistry, 2022, Feb-23, Volume: 13, Issue:2

    Topics:

2022
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
    Journal of chromatography, 1976, Nov-17, Volume: 128, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine

1976
Nonlinear kinetics of trimipramine in depressed patients.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:8

    Topics: Adult; Depressive Disorder; Desipramine; Dibenzazepines; Female; Humans; Male; Middle Aged; Trimipramine

1989
Trimipramine, a tricyclic antidepressant exerting atypical actions on the central noradrenergic system.
    European journal of pharmacology, 1985, Apr-23, Volume: 111, Issue:1

    Topics: Action Potentials; Adenylyl Cyclases; Animals; Brain; Desipramine; Dibenzazepines; Enzyme Activation; Locus Coeruleus; Male; Norepinephrine; Rats; Receptors, Adrenergic, beta; Synaptosomes; Trimipramine

1985
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2

    Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine

1988
Long-term antidepressant treatment reduces neuronal responsiveness to flurazepam: an electrophysiological study in the rat.
    Neuroscience letters, 1987, Jan-27, Volume: 73, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Antidepressive Agents; Chlorpromazine; Cholecystokinin; Citalopram; Desipramine; Flurazepam; Hippocampus; Iontophoresis; Male; Propylamines; Rats; Rats, Inbred Strains; Time Factors; Trimipramine

1987
Use of tricyclic antidepressants in a patient with malignant hyperthermia.
    The American journal of psychiatry, 1987, Volume: 144, Issue:4

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Malignant Hyperthermia; Maprotiline; Trimipramine

1987
An increase in sensitivity of rat cingulate cortical neurones to substance P occurs following withdrawal of chronic administration of antidepressant drugs.
    British journal of pharmacology, 1984, Volume: 81, Issue:4

    Topics: Action Potentials; Animals; Antidepressive Agents; Clomipramine; Desipramine; Diazepam; Drug Resistance; Fluphenazine; Gyrus Cinguli; Male; Neurons; Rats; Substance P; Time Factors; Trimipramine; Zimeldine

1984
Cross hepatotoxicity between tricyclic antidepressants and phenothiazines.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Chemical and Drug Induced Liver Injury; Desipramine; Female; Humans; Liver; Phenothiazines; Structure-Activity Relationship; Trimipramine

1995
Effect of long-term administration of antidepressant drugs on the 5-HT3 receptors that enhance the electrically evoked release of [3H]noradrenaline in the rat hippocampus.
    European journal of pharmacology, 1994, Dec-12, Volume: 271, Issue:1

    Topics: Animals; Antidepressive Agents; Benzamides; Desipramine; Electric Stimulation; Fluoxetine; Hippocampus; In Vitro Techniques; Male; Maprotiline; Moclobemide; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Trimipramine

1994
Inhibition of lysosomal acid sphingomyelinase by agents which reverse multidrug resistance.
    Biochimica et biophysica acta, 1995, 04-06, Volume: 1266, Issue:1

    Topics: Affinity Labels; Animals; Desipramine; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Indolizines; Leukemia P388; Lysosomes; Mianserin; Mice; Phenethylamines; Rhodamine 123; Rhodamines; Sphingomyelin Phosphodiesterase; Trimipramine; Tumor Cells, Cultured; Vasodilator Agents; Vinblastine

1995
Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 16, Issue:5

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Buspirone; Depressive Disorder; Desipramine; Drug Synergism; Female; Fluvoxamine; Humans; Male; Pindolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Trimipramine

1997
Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study.
    Neurochemistry international, 2001, Volume: 38, Issue:1

    Topics: Animals; Antidepressive Agents; Autoradiography; Brain Chemistry; Carrier Proteins; Citalopram; Cyclohexanols; Desipramine; Fluoxetine; Gene Expression Regulation; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Stereotaxic Techniques; Symporters; Trimipramine; Venlafaxine Hydrochloride

2001
Clomipramine and related structures as inhibitors of the skeletal sarcoplasmic reticulum Ca2+ pump.
    Journal of bioenergetics and biomembranes, 2000, Volume: 32, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Calcium; Calcium-Transporting ATPases; Clomipramine; Desipramine; Enzyme Inhibitors; Imipramine; Magnesium; Muscle, Skeletal; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Trimipramine

2000
The involvement of endogenous opioid mechanisms in the antinociceptive effects induced by antidepressant drugs, desipramine and trimipramine.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:4

    Topics: Analgesics; Animals; Antidepressive Agents; Desipramine; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Trimipramine

2006
Electrospray ionization-ion mobility spectrometry as a detection system for three-phase hollow fiber microextraction technique and simultaneous determination of trimipramine and desipramine in urine and plasma samples.
    Analytical and bioanalytical chemistry, 2011, Volume: 399, Issue:10

    Topics: Antidepressive Agents; Desipramine; Humans; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization; Trimipramine

2011
Adsorptive stripping voltammetric determination of imipramine, trimipramine and desipramine employing titanium dioxide nanoparticles and an Amberlite XAD-2 modified glassy carbon paste electrode.
    The Analyst, 2013, Mar-07, Volume: 138, Issue:5

    Topics: Adsorption; Antidepressive Agents, Tricyclic; Carbon; Desipramine; Electrochemical Techniques; Electrodes; Humans; Imipramine; Limit of Detection; Nanoparticles; Pharmaceutical Preparations; Reproducibility of Results; Resins, Synthetic; Titanium; Trimipramine

2013