desipramine and triiodothyronine

desipramine has been researched along with triiodothyronine in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199021 (48.84)18.7374
1990's14 (32.56)18.2507
2000's2 (4.65)29.6817
2010's6 (13.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brunswick, D; Garbutt, J; Jolliff, L; Jonnalagadda, MR; Malekpour, B; Podolak, R; Prange, A; Wilson, I1
Joffe, RT; Singer, W2
Drago, F; Pennisi, G; Pulvirenti, L; Spadaro, F1
Chatelain, F; Martin, P; Massol, J; Puech, AJ1
Anton, RF; Brady, KT1
Belon, JP; Martin, P; Massol, J; Puech, AJ; Soubrié, P1
Arendt, J; Bearn, J; Checkley, SA; Franey, C1
Atterwill, CK; Catto, LC; Dickens, TA; Heal, DJ; Holland, CW; Jones, CA1
Atterwill, CK; Catto, LC; Lee, DM1
Atterwill, CK; Bloomfield, JG; Bristow, LJ; Catto, LC; Elliott, JM; Heal, DJ1
Bondy, SC; Mason, GA; Nemeroff, CB; Prange, AJ; Walker, CH1
Swann, AC1
Chatelain, F; Martin, P; Massol, J; Puech, AJ; Soubrié, P1
Belon, JP; Gaudel, G; Martin, P; Massol, J; Soubrié, P1
Brochet, DM; Martin, P; Simon, P; Soubrié, P1
Prange, AJ1
Hartmann, E1
Blum, JJ2
Imai, S; Ogura, C; Okuma, T; Uchida, Y; Yogi, H1
Extein, I; Gold, MS; Pottash, AL1
Baxter, L; Escobar, J; Halaris, A; Schwarcz, G; Thompson, M; Young, M1
Gold, P; Linnoila, M; Potter, WZ; Wehr, TA1
Goodwin, FK; Lipton, MA; Muscettola, G; Post, RM; Prange, AJ1
Kobayashi, A; Nakazawa, K; Sugita, S; Suzuki, S; Yoshida, T1
Dratman, MB; Gordon, JT; Greenberg, J; Tomlinson, EE1
Dratman, MB; Gordon, JT; Greenberg, J; Martens, DA; Tomlinson, EE1
Ekhatore, N; Loosen, PT; Shelton, RC; Winn, S1
Calvo, R; Dixon, L; Joffe, R; Kish, S; Nobrega, J; Wilson, J1
Joffe, RT; Levitt, AJ; MacDonald, C; Singer, W1
Joffe, RT; Levitt, AJ; Sokolov, ST1
Jarrett, DB; Kennedy, JA; Wellby, ML1
Joffe, RT; Levitt, AJ; Wesson, VA1
Watanabe, A1
Collingwood, CJ; Ritchie, JW; Taylor, PM1
Kinne, A; Roth, S; Schweizer, U1

Reviews

5 review(s) available for desipramine and triiodothyronine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Psychotropic drugs and the thyroid axis: a review of interactions.
    Advances in biochemical psychopharmacology, 1985, Volume: 40

    Topics: Animals; Body Temperature; Brain; Chlorpromazine; Depressive Disorder; Desipramine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Imipramine; Male; Mice; Psychotropic Drugs; Schizophrenia; Thyroid Gland; Thyroid Hormones; Triiodothyronine

1985
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan

1969
Psychopharmacologic treatment of depression.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Affective Disorders, Psychotic; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Electroconvulsive Therapy; Humans; Kinetics; Lithium; Monoamine Oxidase Inhibitors; Nortriptyline; Triiodothyronine

1984

Trials

4 trial(s) available for desipramine and triiodothyronine

ArticleYear
Antidepressants and thyroid hormone levels.
    Acta medica Austriaca, 1992, Volume: 19 Suppl 1

    Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine

1992
A comparison of triiodothyronine and thyroxine in the potentiation of tricyclic antidepressants.
    Psychiatry research, 1990, Volume: 32, Issue:3

    Topics: Adult; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Thyroid Function Tests; Thyroxine; Triiodothyronine

1990
A placebo-controlled comparison of lithium and triiodothyronine augmentation of tricyclic antidepressants in unipolar refractory depression.
    Archives of general psychiatry, 1993, Volume: 50, Issue:5

    Topics: Adult; Ambulatory Care; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium Carbonate; Male; Placebos; Psychiatric Status Rating Scales; Triiodothyronine

1993
Impact of suppression of thyroxine on folate status during acute antidepressant therapy.
    Psychiatry research, 1998, Jun-15, Volume: 79, Issue:2

    Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Chi-Square Distribution; Depression; Desipramine; Double-Blind Method; Drug Resistance; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Regression Analysis; Severity of Illness Index; Thyrotropin; Thyroxine; Time Factors; Treatment Outcome; Triiodothyronine

1998

Other Studies

34 other study(ies) available for desipramine and triiodothyronine

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
Effects of triiodothyronine on drug levels and cardiac function in depressed patients treated with imipramine.
    The American journal of psychiatry, 1979, Volume: 136, Issue:7

    Topics: Adult; Depression; Desipramine; Female; Heart Conduction System; Heart Rate; Humans; Imipramine; Middle Aged; Ovum; Triiodothyronine

1979
Effects of TRH and prolactin in the behavioral despair (swim) model of depression in rats.
    Psychoneuroendocrinology, 1990, Volume: 15, Issue:5-6

    Topics: Aging; Animals; Behavior, Animal; Depression; Desipramine; Injections, Intraventricular; Injections, Subcutaneous; Male; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Swimming; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Transplantation, Homologous; Triiodothyronine

1990
Tricyclic antidepressants, thyroid function, and their relationship with the behavioral responses in rats.
    Biological psychiatry, 1990, Dec-01, Volume: 28, Issue:11

    Topics: Animals; Antidepressive Agents, Tricyclic; Arousal; Avoidance Learning; Clomipramine; Conditioning, Classical; Desipramine; Diabetes Mellitus, Experimental; Escape Reaction; Helplessness, Learned; Imipramine; Male; Rats; Rats, Inbred Strains; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1990
The thyroid axis and desipramine treatment in depression.
    Biological psychiatry, 1989, Mar-15, Volume: 25, Issue:6

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Psychological Tests; Thyroid Function Tests; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1989
Helpless behavior (escape deficits) in streptozotocin-diabetic rats: resistance to antidepressant drugs.
    Psychoneuroendocrinology, 1989, Volume: 14, Issue:1-2

    Topics: Animals; Antidepressive Agents; Brain; Clenbuterol; Clomipramine; Conditioning, Operant; Desipramine; Diabetes Mellitus, Experimental; Electroshock; Escape Reaction; Helplessness, Learned; Imipramine; Insulin; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Triiodothyronine

1989
A study of the effects of desipramine treatment alone and in combination with L-triiodothyronine on 6-sulphatoxymelatonin excretion in depressed patients.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 155

    Topics: Adult; Aged; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Melatonin; Middle Aged; Time Factors; Triiodothyronine

1989
The effects of desipramine (DMI) and electroconvulsive shock (ECS) on the function of the hypothalamo-pituitary-thyroid axis in the rat.
    Psychoneuroendocrinology, 1989, Volume: 14, Issue:5

    Topics: Animals; Desipramine; Electroshock; Hypothalamo-Hypophyseal System; Male; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1989
Interactions of thyroid hormone and tricyclic antidepressants on rat brain beta-adrenoceptor function.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1987, Volume: 11

    Topics: Animals; Brain; Desipramine; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Triiodothyronine

1987
The influence of L-triiodothyronine (T3) on the effects of repeated administration of desipramine or electroconvulsive shock on alpha 2- and beta-adrenoceptor function in the brain of the rat: implications for the potentiation of antidepressant therapy by
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Dioxanes; Electroshock; Idazoxan; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Triiodothyronine

1987
The effects of thyroid state on beta-adrenergic and serotonergic receptors in rat brain.
    Psychoneuroendocrinology, 1987, Volume: 12, Issue:4

    Topics: Animals; Brain; Cerebellum; Corpus Striatum; Desipramine; Hippocampus; Hyperthyroidism; Hypothyroidism; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Thyroid Gland; Thyroxine; Triiodothyronine

1987
Thyroid hormone and norepinephrine: effects on alpha-2, beta, and reuptake sites in cerebral cortex and heart.
    Journal of neural transmission, 1988, Volume: 71, Issue:3

    Topics: Animals; Cerebral Cortex; Desipramine; Dihydroalprenolol; Heart; Hypothyroidism; Male; Methimazole; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Triiodothyronine; Yohimbine

1988
Impaired response of experimental diabetic mice to tricyclics: a possible beta-adrenergic mechanism.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: Animals; Clenbuterol; Clomipramine; Desipramine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypothermia, Induced; Imipramine; Male; Mice; Motor Activity; Receptors, Adrenergic, beta; Thyroxine; Triiodothyronine

1988
Thyroid function and reversal by antidepressant drugs of depressive-like behavior (escape deficits) in rats.
    Neuropsychobiology, 1987, Volume: 18, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Escape Reaction; Hypothyroidism; Imipramine; Male; Nialamide; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Triiodothyronine

1987
Triiodothyronine potentiation of antidepressant-induced reversal of learned helplessness in rats.
    Psychiatry research, 1987, Volume: 21, Issue:3

    Topics: Animals; Avoidance Learning; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Escape Reaction; Helplessness, Learned; Imipramine; Male; Nomifensine; Rats; Rats, Inbred Strains; Triiodothyronine

1987
An adrenergic control system in Tetrahymena.
    Proceedings of the National Academy of Sciences of the United States of America, 1967, Volume: 58, Issue:1

    Topics: Caffeine; Catecholamines; Desipramine; Glycogen; Hydrazines; Isoproterenol; Phenoxybenzamine; Propranolol; Reserpine; Tetrahymena; Triiodothyronine

1967
Effect of adrenergically reactive drugs on peroxisomal enzymes in Tetrahymena.
    Molecular pharmacology, 1968, Volume: 4, Issue:3

    Topics: Aminophylline; Aniline Compounds; Animals; Catalase; D-Amino-Acid Oxidase; Desipramine; Glycogen; Isocitrate Dehydrogenase; Isoproterenol; Lyases; Malate Dehydrogenase; Propranolol; Reserpine; Sympathomimetics; Tetrahymena; Tranquilizing Agents; Tranylcypromine; Triiodothyronine

1968
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:3

    Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood Pressure; Depression; Desipramine; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Motor Activity; Nortriptyline; Pulse; Time Factors; Triiodothyronine; Verbal Behavior

1974
Normal thyroid function in desipramine nonresponders converted to responders by the addition of L-triiodothyronine.
    The American journal of psychiatry, 1984, Volume: 141, Issue:12

    Topics: Adult; Depressive Disorder; Desipramine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypothyroidism; Male; Middle Aged; Radioimmunoassay; Thyroid Function Tests; Thyroid Gland; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1984
Tricyclic antidepressants do not alter thyroid hormone levels in patients suffering from a major affective disorder.
    Psychiatry research, 1981, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Thyroid Hormones; Thyroxine; Triiodothyronine

1981
Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders.
    The American journal of psychiatry, 1982, Volume: 139, Issue:1

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Thyroxine; Triiodothyronine

1982
Triiodothyronine increases desipramine with changing the concentrations of monoamines, in the brain of rat given imipramine.
    European journal of pharmacology, 1993, Feb-09, Volume: 231, Issue:2

    Topics: Animals; Biogenic Monoamines; Biotransformation; Brain; Desipramine; Half-Life; Hydroxyindoleacetic Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Wistar; Serotonin; Triiodothyronine

1993
An acute dose of desmethylimipramine inhibits brain uptake of [125I]3,3',5-triiodothyronine (T3) in thyroxine-induced but not T3-induced hyperthyroid rats: implications for tricyclic antidepressant therapy.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Brain; Desipramine; Dose-Response Relationship, Drug; Hyperthyroidism; Hypothyroidism; Iodide Peroxidase; Iodine Radioisotopes; Ipodate; Male; Rats; Rats, Sprague-Dawley; Thyroxine; Time Factors; Triiodothyronine

1994
Desmethylimipramine, a potent inhibitor of synaptosomal norepinephrine uptake, has diverse effects on thyroid hormone processing in rat brain. II. Effect on in vivo 5'-deiodination of [125I]thyroxine.
    Brain research, 1994, Jan-14, Volume: 634, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Desipramine; Iodine Radioisotopes; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Synaptosomes; Thyroxine; Triiodothyronine

1994
The effects of antidepressants on the thyroid axis in depression.
    Biological psychiatry, 1993, Jan-15, Volume: 33, Issue:2

    Topics: Ambulatory Care; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Male; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine

1993
Desipramine reduces plasma but not brain thyroxine levels.
    Biological psychiatry, 1993, Feb-15, Volume: 33, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Desipramine; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Thyroxine; Triiodothyronine

1993
Thyroid hormone levels before unsuccessful antidepressant therapy are associated with later response to T3 augmentation.
    Psychiatry research, 1997, Mar-24, Volume: 69, Issue:2-3

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Thyroid Hormones; Treatment Failure; Triiodothyronine

1997
Influence of imipramine on the hypothalamic/pituitary/thyroid axis of the rat.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Cells, Cultured; Desipramine; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Imipramine; Injections, Intraperitoneal; Liver; Male; Myocardium; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1997
[The influence of L-triiodothyronine on the action of desipramine on beta and serotonin 2A receptor, monoamines in the rat brain].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1999, Volume: 19, Issue:4

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Brain Chemistry; Desipramine; Dopamine; Drug Synergism; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, beta; Receptors, Serotonin; Triiodothyronine

1999
Effect of hypothyroidism on pathways for iodothyronine and tryptophan uptake into rat adipocytes.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:2

    Topics: Adipocytes; Amino Acids, Cyclic; Animals; Antigens, CD; Biological Transport; Carrier Proteins; Desipramine; Fusion Regulatory Protein-1; Hypothyroidism; Male; Rats; Rats, Wistar; Reference Values; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse; Tryptophan

2001
The tricyclic antidepressant desipramine inhibits T3 import into primary neurons.
    Neuroscience letters, 2010, Jun-30, Volume: 478, Issue:1

    Topics: Amino Acid Transport Systems, Neutral; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Cells, Cultured; Cerebral Cortex; Desipramine; Dogs; Humans; Mice; Monocarboxylic Acid Transporters; Neurons; Sulfobromophthalein; Symporters; Triiodothyronine

2010