desipramine and thyroxine

desipramine has been researched along with thyroxine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19909 (34.62)18.7374
1990's12 (46.15)18.2507
2000's3 (11.54)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Joffe, RT; Singer, W2
Drago, F; Pennisi, G; Pulvirenti, L; Spadaro, F1
Chatelain, F; Martin, P; Massol, J; Puech, AJ1
Baumgartner, A; Campos-Barros, A; Meinhold, MS1
Anton, RF; Brady, KT1
Atterwill, CK; Catto, LC; Dickens, TA; Heal, DJ; Holland, CW; Jones, CA1
Bondy, SC; Mason, GA; Nemeroff, CB; Prange, AJ; Walker, CH1
Chatelain, F; Martin, P; Massol, J; Puech, AJ; Soubrié, P1
Baxter, L; Escobar, J; Halaris, A; Schwarcz, G; Thompson, M; Young, M1
Extein, I; Gold, MS; Pottash, AL1
Gold, P; Linnoila, M; Potter, WZ; Wehr, TA1
Goodwin, FK; Lipton, MA; Muscettola, G; Post, RM; Prange, AJ1
Dratman, MB; Gordon, JT; Greenberg, J; Tomlinson, EE1
Dratman, MB; Gordon, JT; Greenberg, J; Martens, DA; Tomlinson, EE1
Ekhatore, N; Loosen, PT; Shelton, RC; Winn, S1
Calvo, R; Dixon, L; Joffe, R; Kish, S; Nobrega, J; Wilson, J1
Benazzi, F; Ciucci, G1
Jarrett, DB; Kennedy, JA; Wellby, ML1
Joffe, RT; Levitt, AJ; Wesson, VA1
Collingwood, CJ; Ritchie, JW; Taylor, PM1

Reviews

2 review(s) available for desipramine and thyroxine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for desipramine and thyroxine

ArticleYear
Antidepressants and thyroid hormone levels.
    Acta medica Austriaca, 1992, Volume: 19 Suppl 1

    Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Humans; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine

1992
A comparison of triiodothyronine and thyroxine in the potentiation of tricyclic antidepressants.
    Psychiatry research, 1990, Volume: 32, Issue:3

    Topics: Adult; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Thyroid Function Tests; Thyroxine; Triiodothyronine

1990
Impact of suppression of thyroxine on folate status during acute antidepressant therapy.
    Psychiatry research, 1998, Jun-15, Volume: 79, Issue:2

    Topics: Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Chi-Square Distribution; Depression; Desipramine; Double-Blind Method; Drug Resistance; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Regression Analysis; Severity of Illness Index; Thyrotropin; Thyroxine; Time Factors; Treatment Outcome; Triiodothyronine

1998

Other Studies

21 other study(ies) available for desipramine and thyroxine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Effects of TRH and prolactin in the behavioral despair (swim) model of depression in rats.
    Psychoneuroendocrinology, 1990, Volume: 15, Issue:5-6

    Topics: Aging; Animals; Behavior, Animal; Depression; Desipramine; Injections, Intraventricular; Injections, Subcutaneous; Male; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Swimming; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Transplantation, Homologous; Triiodothyronine

1990
Tricyclic antidepressants, thyroid function, and their relationship with the behavioral responses in rats.
    Biological psychiatry, 1990, Dec-01, Volume: 28, Issue:11

    Topics: Animals; Antidepressive Agents, Tricyclic; Arousal; Avoidance Learning; Clomipramine; Conditioning, Classical; Desipramine; Diabetes Mellitus, Experimental; Escape Reaction; Helplessness, Learned; Imipramine; Male; Rats; Rats, Inbred Strains; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1990
Chronic desimipramine treatment enhances thyroxine deiodination in rat brain.
    Psychiatry research, 1990, Volume: 34, Issue:2

    Topics: Animals; Brain; Desipramine; Enzyme Activation; Iodide Peroxidase; Isoenzymes; Male; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine, Reverse

1990
The thyroid axis and desipramine treatment in depression.
    Biological psychiatry, 1989, Mar-15, Volume: 25, Issue:6

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Psychological Tests; Thyroid Function Tests; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1989
The effects of desipramine (DMI) and electroconvulsive shock (ECS) on the function of the hypothalamo-pituitary-thyroid axis in the rat.
    Psychoneuroendocrinology, 1989, Volume: 14, Issue:5

    Topics: Animals; Desipramine; Electroshock; Hypothalamo-Hypophyseal System; Male; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1989
The effects of thyroid state on beta-adrenergic and serotonergic receptors in rat brain.
    Psychoneuroendocrinology, 1987, Volume: 12, Issue:4

    Topics: Animals; Brain; Cerebellum; Corpus Striatum; Desipramine; Hippocampus; Hyperthyroidism; Hypothyroidism; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Thyroid Gland; Thyroxine; Triiodothyronine

1987
Impaired response of experimental diabetic mice to tricyclics: a possible beta-adrenergic mechanism.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: Animals; Clenbuterol; Clomipramine; Desipramine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypothermia, Induced; Imipramine; Male; Mice; Motor Activity; Receptors, Adrenergic, beta; Thyroxine; Triiodothyronine

1988
Normal thyroid function in desipramine nonresponders converted to responders by the addition of L-triiodothyronine.
    The American journal of psychiatry, 1984, Volume: 141, Issue:12

    Topics: Adult; Depressive Disorder; Desipramine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypothyroidism; Male; Middle Aged; Radioimmunoassay; Thyroid Function Tests; Thyroid Gland; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1984
Does subclinical hypothyroidism predispose to tricyclic-induced rapid mood cycles?
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:7

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Hypothyroidism; Lithium; Lithium Carbonate; Thyrotropin-Releasing Hormone; Thyroxine

1982
Tricyclic antidepressants do not alter thyroid hormone levels in patients suffering from a major affective disorder.
    Psychiatry research, 1981, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Thyroid Hormones; Thyroxine; Triiodothyronine

1981
Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders.
    The American journal of psychiatry, 1982, Volume: 139, Issue:1

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Thyroxine; Triiodothyronine

1982
An acute dose of desmethylimipramine inhibits brain uptake of [125I]3,3',5-triiodothyronine (T3) in thyroxine-induced but not T3-induced hyperthyroid rats: implications for tricyclic antidepressant therapy.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Brain; Desipramine; Dose-Response Relationship, Drug; Hyperthyroidism; Hypothyroidism; Iodide Peroxidase; Iodine Radioisotopes; Ipodate; Male; Rats; Rats, Sprague-Dawley; Thyroxine; Time Factors; Triiodothyronine

1994
Desmethylimipramine, a potent inhibitor of synaptosomal norepinephrine uptake, has diverse effects on thyroid hormone processing in rat brain. II. Effect on in vivo 5'-deiodination of [125I]thyroxine.
    Brain research, 1994, Jan-14, Volume: 634, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Desipramine; Iodine Radioisotopes; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Synaptosomes; Thyroxine; Triiodothyronine

1994
The effects of antidepressants on the thyroid axis in depression.
    Biological psychiatry, 1993, Jan-15, Volume: 33, Issue:2

    Topics: Ambulatory Care; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Male; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine

1993
Desipramine reduces plasma but not brain thyroxine levels.
    Biological psychiatry, 1993, Feb-15, Volume: 33, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Desipramine; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Thyroxine; Triiodothyronine

1993
Neuropathy associated with tricyclic antidepressants.
    International journal of geriatric psychiatry, 1997, Volume: 12, Issue:8

    Topics: Alprazolam; Antidepressive Agents, Tricyclic; Desipramine; Female; Humans; Middle Aged; Nortriptyline; Peripheral Nervous System Diseases; Thyroxine

1997
Influence of imipramine on the hypothalamic/pituitary/thyroid axis of the rat.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Cells, Cultured; Desipramine; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Imipramine; Injections, Intraperitoneal; Liver; Male; Myocardium; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1997
Effect of hypothyroidism on pathways for iodothyronine and tryptophan uptake into rat adipocytes.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 280, Issue:2

    Topics: Adipocytes; Amino Acids, Cyclic; Animals; Antigens, CD; Biological Transport; Carrier Proteins; Desipramine; Fusion Regulatory Protein-1; Hypothyroidism; Male; Rats; Rats, Wistar; Reference Values; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse; Tryptophan

2001