desipramine and thiophenes

desipramine has been researched along with thiophenes in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's3 (15.79)18.2507
2000's14 (73.68)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Eckhardt, SB; Ferris, RM; Maxwell, RA; Tang, FL; Woodward, EC1
Lakoski, JM; Smith, JE1
Lucki, I; Rénéric, JP1
Maekawa, M; Murayama, T; Narita, H; Nomura, Y; Ono, S1
Maekawa, M; Murayama, T; Nomura, Y1
Ayan-Oshodi, M; Gonzales, CR; Knadler, MP; Kuan, HY; Lim, M; Pan, A; Reddy, S; Sathirakul, K; Skinner, MH; Wise, SD; Yeo, KP1
Dawson, LA; Li, P1
Bieck, PR; Bymaster, FP; Chalon, SA; Granier, LA; Hirth, C; Joliat, MJ; Potter, WZ; Vandenhende, FR1
Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA1
Chalon, S; Granier, LA; Lainey, E; Pereira, A; Staner, L; Vandenhende, F; Watkin, JG1
Dobson, D; Farde, L; Hall, H; Halldin, C; Innis, RB; Mozley, PD; Pike, VW; Schou, M1
Frazer, A; Gould, GG; Javors, MA1
Eastwood, BJ; Jones, CK; Need, AB; Shannon, HE1
Burczynski, ME; Connolly, SM; Fatato, P; Guico-Pabia, C; Isler, JA; Jiang, Q; Nichols, AI; Patroneva, A; Paul, J; Pedersen, R1
Holloway, RG; Noyes, K; O'Connor, AB1
Guico-Pabia, CJ; Helzner, EC; Nichols, AI; Patroneva, AL; Paul, J; Preskorn, SH1
Berrocoso, E; Mico, JA1
Patel, TA; Rastogi, R; Swarm, RA1

Reviews

2 review(s) available for desipramine and thiophenes

ArticleYear
Effect of desvenlafaxine on the cytochrome P450 2D6 enzyme system.
    Journal of psychiatric practice, 2008, Volume: 14, Issue:6

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Cytochrome P-450 CYP2D6; Depressive Disorder, Major; Desipramine; Desvenlafaxine Succinate; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Health Status; Humans; Paroxetine; Thiophenes

2008
Case scenario: opioid association with serotonin syndrome: implications to the practitioners.
    Anesthesiology, 2011, Volume: 115, Issue:6

    Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Depressive Disorder; Desipramine; Drug Interactions; Duloxetine Hydrochloride; Fentanyl; Humans; Male; Methadone; Middle Aged; Oxycodone; Polypharmacy; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Sulfonamides; Thiophenes; Transdermal Patch

2011

Trials

3 trial(s) available for desipramine and thiophenes

ArticleYear
Duloxetine increases serotonin and norepinephrine availability in healthy subjects: a double-blind, controlled study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:9

    Topics: Adult; Antidepressive Agents; Blood Pressure; Cross-Over Studies; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Heart Rate; Humans; Male; Mandelic Acids; Methoxyhydroxyphenylglycol; Norepinephrine; Normetanephrine; Serotonin; Sympathomimetics; Thiophenes; Time Factors; Tyramine

2003
Comparative effects of duloxetine and desipramine on sleep EEG in healthy subjects.
    Psychopharmacology, 2005, Volume: 177, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cross-Over Studies; Desipramine; Double-Blind Method; Duloxetine Hydrochloride; Electroencephalography; Female; Humans; Male; Norepinephrine; Polysomnography; Serotonin; Sleep; Sleep Stages; Surveys and Questionnaires; Thiophenes

2005
An assessment of drug-drug interactions: the effect of desvenlafaxine and duloxetine on the pharmacokinetics of the CYP2D6 probe desipramine in healthy subjects.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:12

    Topics: Adult; Antidepressive Agents; Area Under Curve; Biotransformation; Cross-Over Studies; Cyclohexanols; Cytochrome P-450 CYP2D6; Desipramine; Desvenlafaxine Succinate; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Thiophenes

2008

Other Studies

14 other study(ies) available for desipramine and thiophenes

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Structure-activity relationships for potent phthalane and thiophthalane inhibitors of norepinephrine uptake. A comparison with desipramine and related compounds.
    Molecular pharmacology, 1980, Volume: 17, Issue:3

    Topics: Animals; Antidepressive Agents; Benzofurans; Desipramine; Hypothalamus; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Norepinephrine; Rabbits; Rats; Stereoisomerism; Structure-Activity Relationship; Sympathetic Nervous System; Synaptosomes; Thiophenes

1980
Electrophysiological study of the effects of the reuptake inhibitor duloxetine on serotonergic responses in the aging hippocampus.
    Pharmacology, 1997, Volume: 55, Issue:2

    Topics: Action Potentials; Aging; Animals; Antidepressive Agents, Second-Generation; Desipramine; Duloxetine Hydrochloride; Female; Hippocampus; Iontophoresis; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Thiophenes

1997
Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test.
    Psychopharmacology, 1998, Volume: 136, Issue:2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Cyclopropanes; Desipramine; Duloxetine Hydrochloride; Fluoxetine; Male; Milnacipran; Motor Activity; Rats; Rats, Sprague-Dawley; Thiophenes

1998
The effects of T-588, a novel cognitive enhancer, on noradrenaline uptake and release in rat cerebral cortical slices.
    Japanese journal of pharmacology, 1998, Volume: 77, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Calcium Chloride; Central Nervous System Stimulants; Cerebral Cortex; Desipramine; Diethylamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Norepinephrine; Potassium Chloride; Rats; Rats, Wistar; Reserpine; Thiophenes; Tyramine

1998
Involvement of noradrenaline transporters in S-nitrosocysteine-stimulated noradrenaline release from rat brain slices: existence of functional Na(+)-independent transporter activity.
    Neurochemistry international, 2001, Volume: 38, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Biological Transport; Brain; Carrier Proteins; Central Nervous System Stimulants; Cerebral Cortex; Cysteine; Desipramine; Diethylamines; Hippocampus; In Vitro Techniques; Male; Nitroso Compounds; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Ouabain; Potassium Chloride; Rats; Rats, Wistar; Reserpine; S-Nitrosothiols; Sodium; Symporters; Thiophenes; Tritium

2001
Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers.
    Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Area Under Curve; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Desipramine; Drug Administration Schedule; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Paroxetine; Reference Values; Selective Serotonin Reuptake Inhibitors; Thiophenes

2003
Effects of 5-HT(6) receptor blockade on the neurochemical outcome of antidepressant treatment in the frontal cortex of the rat.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Cyclohexanols; Depressive Disorder; Desipramine; Drug Synergism; Extracellular Space; Fluoxetine; Glutamic Acid; Male; Microdialysis; Neurons; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sulfonamides; Synaptic Transmission; Thiophenes; Venlafaxine Hydrochloride

2003
Different prejunctional and postjunctional responses to angiotensin II and AT1-receptor inhibition: influence of maturation.
    Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:3

    Topics: Acrylates; Aging; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Desipramine; Electrophysiology; Imidazoles; Male; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; Tetrodotoxin; Thiophenes; Vasoconstriction

2004
Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Autopsy; Autoradiography; Brain; Desipramine; Duloxetine Hydrochloride; Fluorine Radioisotopes; Humans; Morpholines; Postmortem Changes; Radioligand Assay; Thiophenes

2005
Effect of chronic administration of duloxetine on serotonin and norepinephrine transporter binding sites in rat brain.
    Biological psychiatry, 2007, Jan-15, Volume: 61, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Autoradiography; Brain; Chromatography, High Pressure Liquid; Desipramine; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Male; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Thiophenes

2007
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition.
    Neuropharmacology, 2006, Volume: 51, Issue:7-8

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistry; Carrageenan; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Duloxetine Hydrochloride; Edema; Fluoxetine; Hot Temperature; Hyperalgesia; Male; Norepinephrine; Paroxetine; Pressure; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Thiophenes; Venlafaxine Hydrochloride

2006
A cost-utility comparison of four first-line medications in painful diabetic neuropathy.
    PharmacoEconomics, 2008, Volume: 26, Issue:12

    Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Desipramine; Diabetic Neuropathies; Duloxetine Hydrochloride; Economics, Pharmaceutical; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes

2008
Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression.
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:8

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Codeine; Depression; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Enzyme Inhibitors; Hindlimb Suspension; Male; Mice; Motor Activity; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes; Tramadol

2009