desipramine and sulpiride

desipramine has been researched along with sulpiride in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19907 (19.44)18.7374
1990's11 (30.56)18.2507
2000's11 (30.56)29.6817
2010's7 (19.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Caron, G; Ermondi, G1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Jones, CR; Van den Buuse, M; Wagner, J1
Dafny, N; Dougherty, PM; Qiao, JT; Wiggins, RC3
Hutson, PH; Suman-Chauhan, N1
Cervo, L; Grignaschi, G; Samanin, R1
Cools, AR1
Borsini, F; D'Aranno, V; Lecci, A; Mancinelli, A; Meli, A1
Roth, RH; Wolf, ME1
Cervo, L; Samanin, R1
Gugath, M; Laakmann, G; Mueller, OA; Stalla, GK; Treusch, J; Wahlster, U; Wittmann, M1
Borsini, F; Nowakowska, E; Samanin, R1
Dall'Olio, R; Gaggi, R; Gandolfi, O; Montanaro, N; Vaccheri, A1
Kulkarni, SK; Sharma, A2
Florijn, WJ; Gispen, WH; Mulder, AH; Versteeg, DH1
Baranyi, M; Bencsics, A; Hashim, A; Lajtha, A; Sershen, H; Vizi, ES1
Fujiseki, Y; Inagaki, C; Kinoshita, T; Okugawa, G; Omori, K; Suzukawa, J1
Balu, R; Davidson, C; Ellinwood, EH; Lee, TH1
Miura, J1
Díaz, E; Israel, A; Silva, M1
Aiso, S; Ito, M; Katada, M; Kawasaki, A; Matsuoka, M; Nishizawa, K; Terashita, K; Torii, K1
Atallah, BV; Finkbeiner, S; Gittis, AH; Hang, GB; Kreitzer, AC; LaDow, ES; Shoenfeld, LR1
Barceló, D; Gros, M; Kookana, RS; Llorca, M; Rodriguez-Mozaz, S; Williams, M1

Trials

1 trial(s) available for desipramine and sulpiride

ArticleYear
Effects of psychotropic drugs (desimipramine, chlorimipramine, sulpiride and diazepam) on the human HPA axis.
    Psychopharmacology, 1984, Volume: 84, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Clomipramine; Desipramine; Diazepam; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Psychotropic Drugs; Sulpiride

1984

Other Studies

35 other study(ies) available for desipramine and sulpiride

ArticleYear
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Brain dopamine D-2 receptor mechanisms in spontaneously hypertensive rats.
    Brain research bulletin, 1992, Volume: 28, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Benzazepines; Brain; Desipramine; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Iodine Radioisotopes; Male; Motor Activity; Norepinephrine; Organ Specificity; Prolactin; Prosencephalon; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin; Stereotyped Behavior; Sulpiride; Taste

1992
Cocaine interaction with sulpiride, methysergide, naloxone and desipramine: neurophysiological effects of mesolimbic and neostriatal neuronal activity.
    NIDA research monograph, 1990, Volume: 105

    Topics: Animals; Caudate Nucleus; Cocaine; Desipramine; Drug Interactions; In Vitro Techniques; Limbic System; Methysergide; Naloxone; Neurons; Putamen; Rats; Rats, Inbred Strains; Sulpiride

1990
Activation of postsynaptic striatal dopamine receptors, monitored by efflux of cAMP in vivo.
    Neuropharmacology, 1990, Volume: 29, Issue:11

    Topics: Animals; Benzazepines; Colforsin; Corpus Striatum; Cyclic AMP; Desipramine; Dopamine Agents; Hydroxydopamines; Kinetics; Male; Oxazines; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synapses

1990
The role of the mesolimbic dopaminergic system in the desipramine effect in the forced swimming test.
    European journal of pharmacology, 1990, Mar-13, Volume: 178, Issue:1

    Topics: Animals; Depression; Desipramine; Dopamine; Fluphenazine; Hydroxydopamines; Injections; Limbic System; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Swimming; Synapses; Synaptic Transmission

1990
Effects of microiontophoretic application of cocaine, alone and with receptor antagonists, upon the neurons of the medial prefrontal cortex, nucleus accumbens and caudate nucleus of rats.
    Neuropharmacology, 1990, Volume: 29, Issue:4

    Topics: Animals; Caudate Nucleus; Cerebral Cortex; Cocaine; Desipramine; Electrodes; In Vitro Techniques; Iontophoresis; Male; Methysergide; Naloxone; Neurons; Nucleus Accumbens; Rats; Rats, Inbred Strains; Sulpiride; Thalamic Nuclei

1990
Microiontophoresis of cocaine, desipramine, sulpiride, methysergide, and naloxone in habenula and parafasciculus.
    Experimental neurology, 1990, Volume: 108, Issue:3

    Topics: Animals; Antidepressive Agents; Cocaine; Corpus Striatum; Desipramine; Diencephalon; Dose-Response Relationship, Drug; Iontophoresis; Male; Methysergide; Naloxone; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Sulpiride; Thalamic Nuclei

1990
The nucleus accumbens and antidepressants: modulation of ergometrine-induced hyperactivity by typical and atypical antidepressants and neuroleptics in rats.
    Psychopharmacology, 1987, Volume: 92, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Clorgyline; Clozapine; Desipramine; Ergonovine; Male; Mianserin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sulpiride; Zimeldine

1987
Stimulation of dopamine D-2 but not D-1 receptors reduces immobility time of rats in the forced swimming test: implication for antidepressant activity.
    European journal of pharmacology, 1988, Apr-13, Volume: 148, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Behavior, Animal; Benzazepines; Desipramine; Dopamine Antagonists; Ergolines; Locomotion; Male; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Swimming

1988
Dopamine neurons projecting to the medial prefrontal cortex possess release-modulating autoreceptors.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: Animals; Cerebral Cortex; Desipramine; Dose-Response Relationship, Drug; Indoles; Male; Neurons; Nomifensine; Potassium; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Sulpiride

1987
Evidence that dopamine mechanisms in the nucleus accumbens are selectively involved in the effect of desipramine in the forced swimming test.
    Neuropharmacology, 1987, Volume: 26, Issue:10

    Topics: Animals; Corpus Striatum; Desipramine; Dopamine; Injections; Limbic System; Male; Nucleus Accumbens; Rats; Septal Nuclei; Substantia Nigra; Sulpiride; Swimming

1987
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
    Life sciences, 1984, Mar-19, Volume: 34, Issue:12

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidine; Clozapine; Depressive Disorder; Desipramine; Dibenzazepines; Haloperidol; Humans; Male; Metoclopramide; Phentolamine; Prazosin; Propranolol; Rats; Sulpiride

1984
Antidepressant versus neuroleptic activities of sulpiride isomers on four animal models of depression.
    Psychopharmacology, 1984, Volume: 83, Issue:1

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Temperature; Depressive Disorder; Desipramine; Haloperidol; Helplessness, Learned; Humans; Hypnotics and Sedatives; Male; Rats; Rats, Inbred Strains; Stereoisomerism; Sulpiride

1984
Dopamine receptor mediated antidepressant action of B-HT 920 in mice.
    Indian journal of experimental biology, 1994, Volume: 32, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Azepines; Desipramine; Drug Interactions; Escape Reaction; Female; Haloperidol; Male; Mice; Motor Activity; Receptors, Dopamine; Reserpine; Sulpiride; Swimming; Yohimbine

1994
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation.
    Indian journal of experimental biology, 1994, Volume: 32, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipramine; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Muscle Contraction; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reserpine; Sulpiride; Yohimbine

1994
Adrenocorticotropin/alpha-melanocyte-stimulating hormone (ACTH/MSH)-like peptides modulate adenylate cyclase activity in rat brain slices: evidence for an ACTH/MSH receptor-coupled mechanism.
    Journal of neurochemistry, 1993, Volume: 60, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Desipramine; Dopamine; Dose-Response Relationship, Drug; Ergolines; In Vitro Techniques; Kinetics; Male; Organ Specificity; Oxidopamine; Quinpirole; Rats; Rats, Wistar; Receptors, Corticotropin; Receptors, Pituitary Hormone; Sulpiride

1993
Dopamine, as well as norepinephrine, is a link between noradrenergic nerve terminals and splenocytes.
    Brain research, 1997, Jul-04, Volume: 761, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Berberine; Clonidine; Desipramine; Dopamine; Dopamine Antagonists; Electric Stimulation; Male; Muscarinic Agonists; Norepinephrine; Oxotremorine; Presynaptic Terminals; Rats; Rats, Wistar; Spleen; Sulpiride; Sympathomimetics; Tritium

1997
Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.
    Journal of neuroendocrinology, 1999, Volume: 11, Issue:11

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Desipramine; Dexamethasone; Gene Expression Regulation; Haloperidol; Hippocampus; Ketanserin; Mianserin; Neurons; Paroxetine; Phentolamine; Propranolol; Radioligand Assay; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Sulpiride; Transcription, Genetic; Tritium

1999
Differential time-course profiles of dopamine release and uptake changes induced by three dopamine uptake inhibitors.
    Synapse (New York, N.Y.), 2001, Sep-15, Volume: 41, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Benzazepines; Brain Chemistry; Clomipramine; Cocaine; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sulpiride

2001
[Effects of antidepressants on the expression of rat brain dopamine receptors].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 2002, Volume: 77, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents; Brain; Desipramine; Male; Rats; Rats, Wistar; Receptors, Dopamine; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Sulpiride

2002
Role of brain dopaminergic system in the adrenomedullin-induced diuresis and natriuresis.
    Pharmacological research, 2003, Volume: 48, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Adrenomedullin; Animals; Benzazepines; Brain; Catecholamines; Chromatography, High Pressure Liquid; Desipramine; Diuresis; Dopamine; Dopamine Antagonists; Injections, Intraventricular; Male; Natriuresis; Oxidopamine; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Remoxipride; Sulpiride; Sympatholytics

2003
Antidepressant-like effect of Cordyceps sinensis in the mouse tail suspension test.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:9

    Topics: 5-Hydroxytryptophan; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Bupropion; Chromatography, Supercritical Fluid; Clorgyline; Cordyceps; Desipramine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Fluoxetine; Head Movements; Hindlimb Suspension; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Motor Activity; Prazosin; Serotonin Antagonists; Sulpiride; Water

2007
Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine.
    Neuron, 2011, Sep-08, Volume: 71, Issue:5

    Topics: Action Potentials; Animals; Axons; Benzazepines; Biophysics; Computer Simulation; Corpus Striatum; Desipramine; Dopamine; Dopamine Antagonists; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; In Vitro Techniques; Interneurons; Lysine; Mice; Models, Neurological; Nerve Net; Neural Inhibition; Oxidopamine; Parvalbumins; Sulpiride; Sympatholytics; Time Factors; Tyrosine 3-Monooxygenase; Vesicular Inhibitory Amino Acid Transport Proteins

2011
Photolysis of the antidepressants amisulpride and desipramine in wastewaters: Identification of transformation products formed and their fate.
    The Science of the total environment, 2015, Oct-15, Volume: 530-531

    Topics: Amisulpride; Antidepressive Agents; Desipramine; Environmental Monitoring; Photolysis; Sulpiride; Wastewater; Water Pollutants, Chemical

2015