desipramine and sertraline

desipramine has been researched along with sertraline in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19903 (4.29)18.7374
1990's31 (44.29)18.2507
2000's15 (21.43)29.6817
2010's19 (27.14)24.3611
2020's2 (2.86)2.80

Authors

AuthorsStudies
Costanzo, MJ; Gardocki, JF; Maryanoff, BE; McComsey, DF; Nortey, SO; Schneider, CR; Setler, PE; Shank, RP1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Buck, LB; Petrascheck, M; Ye, X1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Bush, LR; Campbell, UC; Engel, SR; Hardy, LW; Hewitt, MC; Koch, P; Ma, J; Malcolm, SC; Saraswat, LD; Schreiber, R; Shao, L; Spear, KL; Spicer, NA; Varney, MA; Wang, F1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kriete, M; Rapoport, JL; Ryland, DH1
Grealy, M; O'Donnell, JM1
Doogan, DP1
Curtis, AL; Valentino, RJ1
Fischette, CT; Reith, ME; Wiener, HL1
Ball, WA; Gresch, PJ; Morrison, AR; Ross, RJ1
Ball, WA; Gresch, PJ; Levitt, DR; Morrison, AR; Ross, RJ1
Curtis, AL; Parris, DG; Valentino, RJ; Wehby, RG1
Butler, J; Leonard, BE; Tannian, M1
Fabian, A; Fields, HL; Pazoles, CJ; Taiwo, YO1
Duman, RS; Morinobu, S; Nibuya, M1
Coutaux, AF; Mooney, JJ; Wirth, DF1
Alderman, J; Chung, M; Harris, S; Harrison, W; Messig, M; Preskorn, SH1
Asnis, G; Barros, J1
Overstreet, DH; Pucilowski, O1
Calabrese, JR; Rapport, DJ1
Anton, RF; Cunningham, T; Lydiard, RB1
Goodman, WK; McDougle, CJ; Price, LH1
Freeman, EW; Rickels, K; Sondheimer, SJ; Wittmaack, FM1
Burke, MJ; Harvey, AT; Preskorn, SH1
Duman, RS; Nestler, EJ; Nibuya, M1
Preskorn, SH1
Berman, R; Charney, DS; Delgado, PL; Heninger, GR; Krystal, JH; Miller, HL; Salomon, RM1
Acquadro, MA; Montgomery, WW1
Ahern, D; Ball, SE; Kao, J; Scatina, J1
Alderman, J; Allison, J; Chung, M; Greenblatt, DJ; Harrison, W; Penenberg, D; Preskorn, SH1
Bergstrom, RF; Cerimele, BJ; Goldberg, MJ; Kurtz, DL1
Anand, A; Barr, LC; Goodman, WK; McDougle, CJ; Price, LH1
Bagby, RM; Dickens, SE; Joffe, R; Kennedy, SH; Levitt, A; Minifie, CE; Schuller, DR1
Onal, A; Tuğlular, I1
Bagby, RM; Joffe, RT; Kennedy, SH; Levitan, RD; Levitt, AJ1
Freeman, EW; Polansky, M; Rickels, K; Sondheimer, SJ2
Benmansour, S; Cecchi, M; Frazer, A; Gerhardt, GA; Gould, GG; Javors, MA; Morilak, DA1
Black, DW; Chapman, D; Clary, C; Greist, JH; Harrison, W; Hoehn-Saric, R; Lydiard, B; McElroy, S; Ninan, P; Stahl, S; Zajecka, J1
Bayer, BM; Pellegrino, TC1
Greenberg, BD; Hoehn-Saric, R; McLeod, DR; Pearlson, GD; Schlaepfer, TE; Wong, SH1
Carrey, NJ; Clements, R; Dursun, S; MacMaster, FP; Renton, K; Waschbusch, D1
Freeman, EW; Frye, CA; Martin, PA; Rickels, K; Smith, SS1
Chen, F; Lawrence, AJ2
Cryan, JF; Dalvi, A; Friedland, JC; Hirsch, BR; Jin, SH; Lucki, I; O'Leary, OF; Ouyang, M; Page, ME; Thomas, SA1
Eastwood, BJ; Jones, CK; Need, AB; Shannon, HE1
Brooks, BW; Frazer, A; Gould, GG1
Aksoz, E; Aksoz, T; Bilge, SS; Celik, S; Diren, HB; Ilkaya, F1
Craft, RM; Kostick, ML; Rogers, JA; Tsutsui, KT; White, CL1
Barone, P1
Frazer, A; Furmaga, H; Shah, A1
Frazer, A; Furmaga, H; Sadhu, M1
Abdollahian, E; Azarpazhooh, A; Haghighi, MB; Mokhber, N; Saghebi, A; Samadi, R; Soltanifar, A1
Akindipe, TO; Ipser, JC; Sager, C; Stein, DJ; Wilson, D1
Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X1
Hasegawa, S; Hida, H; Miyake, Y; Mouri, A; Nabeshima, T; Noda, Y; Ozaki, N; Yamada, K; Yoshimi, A1
Aladaghlo, Z; Fakhari, AR; Javanbakht, S; Shaabani, A1
Yamini, Y; Zamani, R1

Reviews

7 review(s) available for desipramine and sertraline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Toleration and safety of sertraline: experience worldwide.
    International clinical psychopharmacology, 1991, Volume: 6 Suppl 2

    Topics: 1-Naphthylamine; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Drug Overdose; Humans; Risk Factors; Sertraline

1991
Pharmacology of locus coeruleus spontaneous and sensory-evoked activity.
    Progress in brain research, 1991, Volume: 88

    Topics: 1-Naphthylamine; Action Potentials; Animals; Antidepressive Agents; Corticotropin-Releasing Hormone; Depression; Depression, Chemical; Desipramine; Drug Tolerance; Electroshock; Humans; Hypothalamo-Hypophyseal System; Locus Coeruleus; Mianserin; Nitroprusside; Pain; Rats; Sertraline; Stress, Physiological

1991
The pharmacotherapy of obsessive-compulsive disorder.
    Pharmacopsychiatry, 1993, Volume: 26 Suppl 1

    Topics: 1-Naphthylamine; Buspirone; Clomipramine; Desipramine; Fluoxetine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Sertraline

1993
Treatment of depressive symptoms in Parkinson's disease.
    European journal of neurology, 2011, Volume: 18 Suppl 1

    Topics: Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Depression; Desipramine; Dopamine Agonists; Humans; Levodopa; Nortriptyline; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline

2011
Pharmacotherapy for anxiety and comorbid alcohol use disorders.
    The Cochrane database of systematic reviews, 2015, Jan-20, Volume: 1

    Topics: Alcohol-Related Disorders; Anxiety; Anxiety Disorders; Buspirone; Comorbidity; Desipramine; Humans; Paroxetine; Phobia, Social; Publication Bias; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic

2015
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

2016

Trials

15 trial(s) available for desipramine and sertraline

ArticleYear
Drug treatment of canine acral lick. An animal model of obsessive-compulsive disorder.
    Archives of general psychiatry, 1992, Volume: 49, Issue:7

    Topics: 1-Naphthylamine; Animals; Clomipramine; Dermatitis; Desipramine; Disease Models, Animal; Dog Diseases; Dogs; Double-Blind Method; Fenfluramine; Fluoxetine; Follow-Up Studies; Grooming; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Serotonin; Sertraline; Ulcer

1992
Pharmacokinetics of desipramine coadministered with sertraline or fluoxetine.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:2

    Topics: 1-Naphthylamine; Antidepressive Agents; Chromatography, High Pressure Liquid; Desipramine; Dextromethorphan; Drug Interactions; Fluoxetine; Humans; Male; Selective Serotonin Reuptake Inhibitors; Sertraline

1994
Sertraline versus desipramine in the treatment of premenstrual syndrome: an open-label trial.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:1

    Topics: 1-Naphthylamine; Adolescent; Adult; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Middle Aged; Premenstrual Syndrome; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

1996
Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression.
    Archives of general psychiatry, 1996, Volume: 53, Issue:2

    Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Brain Chemistry; Depressive Disorder; Desipramine; Diphenhydramine; Dopamine; Fluoxetine; Humans; Mazindol; Methyltyrosines; Norepinephrine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline

1996
Desipramine pharmacokinetics when coadministered with paroxetine or sertraline in extensive metabolizers.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:4

    Topics: 1-Naphthylamine; Adolescent; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Area Under Curve; Cross-Over Studies; Desipramine; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Humans; Male; Middle Aged; Paroxetine; Sertraline

1997
The effect of sertraline on the pharmacokinetics of desipramine and imipramine.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:2

    Topics: 1-Naphthylamine; Adult; Antidepressive Agents, Tricyclic; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Studies; Desipramine; Half-Life; Humans; Imipramine; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sertraline

1997
Addition of desipramine to serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder.
    The American journal of psychiatry, 1997, Volume: 154, Issue:9

    Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Adult; Clomipramine; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

1997
Differential pharmacological treatment response in high angry hostile and low angry hostile depressed patients: a retrospective analysis.
    Journal of affective disorders, 1997, Volume: 45, Issue:3

    Topics: 1-Naphthylamine; Adult; Ambulatory Care; Analysis of Variance; Anger; Cyclohexanols; Depressive Disorder; Desipramine; Female; Hostility; Humans; Male; Paroxetine; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome; Venlafaxine Hydrochloride

1997
Selective alteration of personality in response to noradrenergic and serotonergic antidepressant medication in depressed sample: evidence of non-specificity.
    Psychiatry research, 1999, Jun-30, Volume: 86, Issue:3

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents; Depressive Disorder, Major; Desipramine; Female; Humans; Male; Paroxetine; Personality; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

1999
Differential response to antidepressants in women with premenstrual syndrome/premenstrual dysphoric disorder: a randomized controlled trial.
    Archives of general psychiatry, 1999, Volume: 56, Issue:10

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Placebos; Premenstrual Syndrome; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

1999
Multicenter double-blind comparison of sertraline and desipramine for concurrent obsessive-compulsive and major depressive disorders.
    Archives of general psychiatry, 2000, Volume: 57, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

2000
Concurrent use of oral contraceptives with antidepressants for premenstrual syndromes.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Antidepressive Agents; Contraceptives, Oral; Desipramine; Double-Blind Method; Drug Interactions; Female; Humans; Middle Aged; Polypharmacy; Premenstrual Syndrome; Sertraline; Severity of Illness Index

2001
Cerebral blood flow in obsessive-compulsive patients with major depression: effect of treatment with sertraline or desipramine on treatment responders and non-responders.
    Psychiatry research, 2001, Nov-30, Volume: 108, Issue:2

    Topics: Adult; Aged; Blood Flow Velocity; Cerebral Cortex; Depressive Disorder, Major; Desipramine; Dominance, Cerebral; Double-Blind Method; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Obsessive-Compulsive Disorder; Regional Blood Flow; Sertraline; Tomography, Emission-Computed, Single-Photon; Treatment Outcome

2001
Allopregnanolone levels and symptom improvement in severe premenstrual syndrome.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:5

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Desipramine; Double-Blind Method; Female; Gonadal Steroid Hormones; Humans; Pregnanolone; Premenstrual Syndrome; Sertraline; Severity of Illness Index; Treatment Outcome

2002
Comparison of sertraline, venlafaxine and desipramine effects on depression, cognition and the daily living activities in Alzheimer patients.
    Pharmacopsychiatry, 2014, Volume: 47, Issue:4-5

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Antidepressive Agents; Cognition; Comorbidity; Depressive Disorder, Major; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Sertraline; Treatment Outcome; Venlafaxine Hydrochloride

2014

Other Studies

48 other study(ies) available for desipramine and sertraline

ArticleYear
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry; Dopamine; Isoquinolines; Male; Molecular Conformation; Motor Activity; Norepinephrine; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Synaptosomes; Tetrabenazine

1987
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation

2007
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
    Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

    Topics: Animals; Antidepressive Agents; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Mice; Naphthalenes; Neurotransmitter Uptake Inhibitors; Norepinephrine; Serotonin

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Neuroendocrine response to clonidine and 8-OH-DPAT in rats following chronic administration of desipramine or sertraline.
    British journal of pharmacology, 1992, Volume: 105, Issue:4

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cerebral Cortex; Clonidine; Corticosterone; Desipramine; Dihydroalprenolol; Male; Neurosecretory Systems; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sertraline; Tetrahydronaphthalenes

1992
Sertraline and cocaine-induced locomotion in mice. I. Acute studies.
    Psychopharmacology, 1991, Volume: 103, Issue:3

    Topics: 1-Naphthylamine; Animals; Cocaine; Desipramine; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Serotonin; Serotonin Antagonists; Sertraline; Sex Factors

1991
REM sleep suppression by monoamine reuptake blockade: development of tolerance with repeated drug administration.
    Biological psychiatry, 1990, Aug-01, Volume: 28, Issue:3

    Topics: 1-Naphthylamine; Animals; Brain; Cats; Circadian Rhythm; Desipramine; Dose-Response Relationship, Drug; Female; Naphthalenes; Receptors, Adrenergic; Receptors, Serotonin; Serotonin Antagonists; Sertraline; Sleep, REM

1990
Effects of monoamine reuptake blockade on ponto-geniculo-occipital wave activity.
    Neuropharmacology, 1990, Volume: 29, Issue:10

    Topics: 1-Naphthylamine; Animals; Biological Transport; Cats; Desipramine; Electroencephalography; Electromyography; Electrooculography; Eye Movements; Female; Geniculate Bodies; Norepinephrine; Occipital Lobe; Pons; Serotonin; Serotonin Antagonists; Sertraline; Sleep, REM

1990
Antidepressant actions on brain noradrenergic neurons.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2

    Topics: 1-Naphthylamine; Animals; Brain; Corticotropin-Releasing Hormone; Desipramine; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Injections, Intravenous; Male; Naphthalenes; Neural Conduction; Rats; Rats, Inbred Strains; Sciatic Nerve; Serotonin Antagonists; Sertraline

1990
The chronic effects of desipramine and sertraline on platelet and synaptosomal 5HT uptake in olfactory bulbectomised rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:5

    Topics: 1-Naphthylamine; Amygdala; Animals; Blood Platelets; Cerebral Cortex; Desipramine; Male; Motor Activity; Naphthalenes; Olfactory Bulb; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Serotonin Antagonists; Sertraline; Synaptosomes

1988
Potentiation of morphine antinociception by monoamine reuptake inhibitors in the rat spinal cord.
    Pain, 1985, Volume: 21, Issue:4

    Topics: 1-Naphthylamine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Drug Synergism; Male; Morphine; Nociceptors; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Sertraline; Spinal Cord

1985
Chronic antidepressant treatment down-regulates the induction of c-fos mRNA in response to acute stress in rat frontal cortex.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 12, Issue:3

    Topics: 1-Naphthylamine; Amino Acid Isomerases; Animals; Antidepressive Agents; Carrier Proteins; Desipramine; Down-Regulation; Frontal Lobe; Imipramine; Male; Peptidylprolyl Isomerase; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Sertraline; Stress, Psychological; Time Factors; Tranylcypromine

1995
Neuronal monoamine reuptake inhibitors enhance in vitro susceptibility to chloroquine in resistant Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6

    Topics: 1-Naphthylamine; Animals; Chloroquine; Desipramine; Drug Resistance; Drug Synergism; Fluoxetine; Neurotransmitter Uptake Inhibitors; Plasmodium falciparum; Sertraline

1994
An interaction of sertraline and desipramine.
    The American journal of psychiatry, 1993, Volume: 150, Issue:11

    Topics: 1-Naphthylamine; Depressive Disorder; Desipramine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sertraline

1993
Effect of chronic antidepressant treatment on responses to apomorphine in selectively bred rat strains.
    Brain research bulletin, 1993, Volume: 32, Issue:5

    Topics: 1-Naphthylamine; Animals; Apomorphine; Body Temperature Regulation; Breeding; Depressive Disorder; Desipramine; Disease Models, Animal; Male; Motor Activity; Parasympathetic Nervous System; Rats; Sertraline; Time Factors

1993
Tolerance to fluoxetine.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:5

    Topics: 1-Naphthylamine; Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Female; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Sertraline

1993
Interactions between sertraline and tricyclic antidepressants.
    The American journal of psychiatry, 1993, Volume: 150, Issue:7

    Topics: 1-Naphthylamine; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Interactions; Humans; Imipramine; Male; Selective Serotonin Reuptake Inhibitors; Sertraline

1993
Pharmacokinetics of the newer antidepressants.
    The American journal of medicine, 1996, Volume: 100, Issue:1

    Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Desipramine; Fluoxetine; Humans; Isoenzymes; Liver; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline

1996
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Apr-01, Volume: 16, Issue:7

    Topics: 1-Naphthylamine; Animals; Antidepressive Agents; Base Sequence; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Desipramine; Electric Stimulation; Fluoxetine; Hippocampus; Imipramine; In Situ Hybridization; Male; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, trkB; Receptors, Nerve Growth Factor; RNA, Messenger; Rolipram; Sertraline; Time Factors; Tranylcypromine

1996
Drug-drug interactions.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:5

    Topics: 1-Naphthylamine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Humans; Mixed Function Oxygenases; Paroxetine; Research Design; Selective Serotonin Reuptake Inhibitors; Sertraline

1996
Treatment of chronic paranasal sinus pain with minimal sinus disease.
    The Annals of otology, rhinology, and laryngology, 1996, Volume: 105, Issue:8

    Topics: 1-Naphthylamine; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Desipramine; Humans; Migraine Disorders; Pain; Paranasal Sinuses; Selective Serotonin Reuptake Inhibitors; Sertraline; Sinusitis; Trigeminal Neuralgia

1996
Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:6

    Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclohexanols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Fluoxetine; Fluvoxamine; Frozen Sections; Humans; Hydroxylation; Imipramine; In Vitro Techniques; Lethal Dose 50; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Venlafaxine Hydrochloride

1997
The relationship between pupil diameter and pain by the administration of morphine and antidepressant drugs in mice.
    General pharmacology, 1999, Volume: 33, Issue:1

    Topics: Amitriptyline; Analgesia; Analgesics, Opioid; Animals; Antidepressive Agents; Desipramine; Male; Mice; Morphine; Mydriasis; Pain; Pain Measurement; Pain Threshold; Pupil; Sertraline; Time Factors

1999
Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-01, Volume: 19, Issue:23

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Carrier Proteins; Desipramine; Fluvoxamine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Paroxetine; Phenelzine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sertraline; Time Factors

1999
Specific serotonin reuptake inhibitor-induced decreases in lymphocyte activity require endogenous serotonin release.
    Neuroimmunomodulation, 2000, Volume: 8, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cell Division; Desipramine; Dopamine Uptake Inhibitors; Fenclonine; Fluoxetine; Lymphocyte Activation; Lymphocytes; Male; Mitogens; Neurons; p-Chloroamphetamine; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sertraline

2000
Noradrenergic and serotonergic neuroendocrine responses in prepubertal, peripubertal, and postpubertal rats pretreated with desipramine and sertraline.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2002, Volume: 41, Issue:8

    Topics: Animals; Clonidine; Desipramine; Dose-Response Relationship, Drug; Fenfluramine; Growth Hormone; Male; Neurosecretory Systems; Premedication; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Serotonin; Sertraline; Sexual Maturation

2002
The effects of antidepressant treatment on serotonergic and dopaminergic systems in Fawn-Hooded rats: a quantitative autoradiography study.
    Brain research, 2003, Jun-20, Volume: 976, Issue:1

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Autoradiography; Brain; Carrier Proteins; Desipramine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sertraline

2003
Chronic antidepressant treatment causes a selective reduction of mu-opioid receptor binding and functional coupling to G Proteins in the amygdala of fawn-hooded rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:3

    Topics: Amygdala; Animals; Antidepressive Agents; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Desipramine; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Male; Rats; Receptors, Opioid, mu; Sertraline; Sulfur Radioisotopes

2004
Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, May-25, Volume: 101, Issue:21

    Topics: Animals; Antidepressive Agents; Citalopram; Depression; Desipramine; Dopamine beta-Hydroxylase; Droxidopa; Fluoxetine; Gene Deletion; Mice; Morpholines; Norepinephrine; Paroxetine; Reboxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Tail

2004
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition.
    Neuropharmacology, 2006, Volume: 51, Issue:7-8

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistry; Carrageenan; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Duloxetine Hydrochloride; Edema; Fluoxetine; Hot Temperature; Hyperalgesia; Male; Norepinephrine; Paroxetine; Pressure; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Thiophenes; Venlafaxine Hydrochloride

2006
[(3)H] citalopram binding to serotonin transporter sites in minnow brains.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:3

    Topics: Animals; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Citalopram; Cyprinidae; Desipramine; Dopamine Uptake Inhibitors; Male; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Sertraline

2007
Antidepressant-like effects of echo-planar magnetic resonance imaging in mice determined using the forced swimming test.
    Brain research, 2008, Oct-21, Volume: 1236

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Desipramine; Disease Models, Animal; Echo-Planar Imaging; Immobility Response, Tonic; Male; Mice; Mice, Inbred BALB C; Motor Activity; Sertraline; Swimming; Time Factors

2008
Forced swim test behavior in postpartum rats.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Desipramine; Female; Neurotransmitter Uptake Inhibitors; Nomifensine; Ovariectomy; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Sertraline; Stress, Physiological; Swimming

2010
Serotonergic and noradrenergic pathways are required for the anxiolytic-like and antidepressant-like behavioral effects of repeated vagal nerve stimulation in rats.
    Biological psychiatry, 2011, Nov-15, Volume: 70, Issue:10

    Topics: 5,7-Dihydroxytryptamine; Adrenergic Agents; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Anxiety; Autoradiography; Brain; Desipramine; Disease Models, Animal; Drug Delivery Systems; Exploratory Behavior; Feeding Behavior; Imipramine; Immobility Response, Tonic; Male; Neural Pathways; Norepinephrine; Oxidopamine; Protein Binding; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Antagonists; Sertraline; Swimming; Time Factors; Tritium; Vagus Nerve Stimulation

2011
Comparison of ΔFosB immunoreactivity induced by vagal nerve stimulation with that caused by pharmacologically diverse antidepressants.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:2

    Topics: Affect; Animals; Antidepressive Agents; Brain; Cognition; Desipramine; Immunohistochemistry; Male; Proto-Oncogene Proteins c-fos; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonergic Neurons; Serotonin; Sertraline; Vagus Nerve; Vagus Nerve Stimulation

2012
Dysfunction of Serotonergic and Dopaminergic Neuronal Systems in the Antidepressant-Resistant Impairment of Social Behaviors Induced by Social Defeat Stress Exposure as Juveniles.
    The international journal of neuropsychopharmacology, 2018, 09-01, Volume: 21, Issue:9

    Topics: Animals; Antidepressive Agents; Aripiprazole; Brain; Depressive Disorder, Treatment-Resistant; Desipramine; Disease Models, Animal; Dominance-Subordination; Dopamine; Drug Therapy, Combination; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Norepinephrine; Serotonin; Sertraline; Sexual Maturation; Social Behavior; Stress, Psychological

2018
Gelatin microsphere coated Fe
    Mikrochimica acta, 2021, 02-06, Volume: 188, Issue:3

    Topics: Adsorption; Antidepressive Agents, Tricyclic; Citalopram; Desipramine; Gelatin; Graphite; Humans; Limit of Detection; Magnetic Phenomena; Magnetite Nanoparticles; Microspheres; Nanocomposites; Quantum Dots; Sertraline; Solid Phase Extraction

2021
On-Chip Electromembrane Surrounded Solid Phase Microextraction for Determination of Tricyclic Antidepressants from Biological Fluids Using Poly(3,4-ethylenedioxythiophene)-Graphene Oxide Nanocomposite as a Fiber Coating.
    Biosensors, 2023, Jan-14, Volume: 13, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Limit of Detection; Maprotiline; Nanocomposites; Nortriptyline; Reproducibility of Results; Sertraline; Solid Phase Microextraction

2023