desipramine has been researched along with scopolamine hydrobromide in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (46.15) | 18.7374 |
| 1990's | 6 (15.38) | 18.2507 |
| 2000's | 9 (23.08) | 29.6817 |
| 2010's | 6 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kirkby, RD; Kokkinidis, L | 1 |
| Bähring, A; Brunn, G; Elsner, M; Racké, K; Wessler, I | 1 |
| Anami, K; Setoguchi, M; Yamamoto, Y | 1 |
| Mayer, DJ; Watkins, LR | 1 |
| Borsini, F; d'Aranno, V; Lecci, A; Mancinelli, A; Meli, A | 1 |
| Czyrak, A; Klimek, V; Mogilnicka, E; Wedzony, K | 1 |
| Papeschi, R; Randrup, A | 1 |
| Gröningsson, K; Schill, G | 1 |
| Zetler, G | 1 |
| Slater, P | 1 |
| Vaillant, GE | 1 |
| Gliozzi, E; Pacini, S; Pepeu, G | 1 |
| Morpurgo, C | 1 |
| Burchinsky, SG | 1 |
| O'Donnell, JM; Rider, DP; Seiden, LS; Somani, S | 1 |
| Jones, RS; Olpe, HR; Steinmann, MW | 1 |
| McGuire, PS; Seiden, LS | 1 |
| Howard, RC; Mason, PA; Menkes, DB; Shaw, JP; Spears, GF; Taghavi, E | 1 |
| Hatzidimitriou, G; Markowska, AL; Olton, DS; Ricaurte, GA; Wenk, GL; Wlos, J | 1 |
| Daws, LC; Frazer, A; Lopez, R | 1 |
| Bizot, JC | 1 |
| Misane, I; Ogren, SO | 1 |
| BOFF, E; SCHECKEL, CL | 1 |
| Caboche, J; Girault, JA; Hervé, D; Pagès, C; Valjent, E | 1 |
| Nieoczym, D; Poleszak, E; Socała, K; Wlaź, P; Wyska, E | 1 |
3 review(s) available for desipramine and scopolamine hydrobromide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications.
Topics: Acupuncture Therapy; Analgesia; Animals; Cholecystokinin; Conditioning, Classical; Desipramine; Dimethyl Sulfoxide; Drug Interactions; Electroshock; Endorphins; Enkephalin, Leucine; Mecamylamine; Morphine; N-Methylscopolamine; Naloxone; Naltrexone; Norepinephrine; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Scopolamine; Scopolamine Derivatives; Serotonin; Spinal Cord | 1986 |
Neurotransmitter receptors in the central nervous system and aging: pharmacological aspect (review).
Topics: Adenylyl Cyclases; Aging; Animals; Brain; Desipramine; Dopamine; Dopamine Antagonists; Female; Fluphenazine; Haloperidol; Humans; Male; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Reserpine; Scopolamine; Spiperone; Tetrahydronaphthalenes; Tissue Distribution; Tritium | 1984 |
1 trial(s) available for desipramine and scopolamine hydrobromide
| Article | Year |
|---|---|
Premenstrual syndrome: a double-blind controlled trial of desipramine and methylscopolamine.
Topics: Adolescent; Adult; Cross-Over Studies; Desipramine; Double-Blind Method; Female; Humans; Luteal Phase; Premenstrual Syndrome; Scopolamine; Treatment Outcome | 1995 |
35 other study(ies) available for desipramine and scopolamine hydrobromide
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Determination of log D via automated microfluidic liquid-liquid extraction.
Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Amphetamine sensitization and amygdala kindling: pharmacological evaluation of catecholaminergic and cholinergic mechanisms.
Topics: Acetylcholine; Adenylyl Cyclase Inhibitors; Amphetamine; Amygdala; Animals; Behavior, Animal; Catecholamines; Desipramine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Kindling, Neurologic; Male; Norepinephrine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Scopolamine; Stereotaxic Techniques; Synaptic Transmission | 1991 |
Characterization of endogenous noradrenaline release from intact and epithelium-denuded rat isolated trachea.
Topics: Animals; Chromatography, High Pressure Liquid; Desipramine; Electric Stimulation; Electrochemistry; Epithelium; Female; In Vitro Techniques; Muscle Tonus; Muscle, Smooth; Norepinephrine; Oxotremorine; Potassium; Rats; Rats, Inbred Strains; Scopolamine; Tetrodotoxin; Trachea; Yohimbine | 1991 |
[Pharmacological studies on sufoxazine (Y-8894). (I) Effects on experimental amnesia in mice].
Topics: Amnesia; Animals; Avoidance Learning; Carbon Dioxide; Central Nervous System Stimulants; Desipramine; Electroshock; Humans; Imipramine; Mice; Morpholines; Scopolamine | 1985 |
Cholinergic drug effects on antidepressant-induced behaviour in the forced swimming test.
Topics: Animals; Antidepressive Agents; Atropine; Behavior, Animal; Desipramine; Drug Synergism; Male; Motor Activity; Nomifensine; Pharmaceutical Vehicles; Physical Exertion; Physostigmine; Rats; Scopolamine; Swimming | 1988 |
Desipramine induces yawning behaviour in rats.
Topics: Animals; Antidepressive Agents; Desipramine; Drug Interactions; Haloperidol; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reflex; Scopolamine | 1986 |
Catalepsy, sedation and hypothermia induced by alpha-methyl-p-tyrosine in the rat. An ideal tool for screening of drugs active on central catecholaminergic receptors.
Topics: Amantadine; Animals; Apomorphine; Behavior, Animal; Body Temperature; Brain Chemistry; Catalepsy; Depression, Chemical; Desipramine; Dextroamphetamine; Dihydroxyphenylalanine; Disulfides; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Exploratory Behavior; Humans; Hydrazines; Hypnotics and Sedatives; Male; Methyltyrosines; Motor Activity; Norepinephrine; Posture; Rats; Receptors, Drug; Scopolamine; Time Factors | 1973 |
Thin-layer chromatography of ion pairs on impregnated layers.
Topics: Alkaloids; Amitriptyline; Atropine; Chromatography, Thin Layer; Desipramine; Imipramine; Ions; Scopolamine | 1969 |
Cataleptic state and hypothermia in mice, caused by central cholinergic stimulation and antagonized by anticholinergic and antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Catalepsy; Desipramine; Hexamethonium Compounds; Humans; Hypothermia; Imipramine; Male; Mice; Nicotine; Nicotinic Acids; Nitrophenols; Parasympatholytics; Parasympathomimetics; Phosphoric Acids; Pilocarpine; Pralidoxime Compounds; Scopolamine; Tremorine | 1968 |
Hypothermia following intraventricular injection of hemicholinium-3 in rats.
Topics: Acetylcholine; Amphetamine; Animals; Biphenyl Compounds; Body Temperature; Cerebral Ventricles; Choline; Desipramine; Hexamethonium Compounds; Imipramine; Male; Parasympatholytics; Phentolamine; Rats; Scopolamine | 1969 |
Clinical significance of anticholinergic effects of imipramine-like drugs.
Topics: Amitriptyline; Animals; Atropine; Columbidae; Depression; Desipramine; Diphenhydramine; Humans; Imipramine; Parasympatholytics; Scopolamine | 1969 |
[Amnesic action of some anti-depressive drugs and their effect on cerebral acetylcholine in the rat].
Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Desipramine; Imipramine; Memory; Rats; Scopolamine | 1966 |
Interaction of imipramine and desmethylimipramine with tremorine and oxotremorine in mice.
Topics: Animals; Body Temperature; Desipramine; Dextroamphetamine; Imipramine; Lacrimal Apparatus; Male; Mice; Salivation; Scopolamine; Sweating; Tremorine | 1967 |
The effect of repeated desipramine administration on water intake in rats.
Topics: Amitriptyline; Animals; Body Weight; Desipramine; Dose-Response Relationship, Drug; Drinking Behavior; Drug Tolerance; Male; Rats; Rats, Inbred Strains; Scopolamine; Time Factors | 1982 |
The locus coeruleus: actions of psychoactive drugs.
Topics: Action Potentials; Animals; Atropine; Caffeine; Chlorpromazine; Desipramine; Haloperidol; Locus Coeruleus; Male; Neurons; Nicotine; Norepinephrine; Physostigmine; Psychotropic Drugs; Rats; Scopolamine | 1983 |
The effects of tricyclic antidepressants on performance under a differential-reinforcement-of-low-rates schedule in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Imipramine; Male; Rats; Reinforcement Schedule; Scopolamine | 1980 |
3,4-Methylenedioxymethamphetamine, serotonin and memory.
Topics: 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Brain Chemistry; Desipramine; Immunohistochemistry; Learning; Male; Memory; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Scopolamine; Serotonin | 1993 |
Effects of antidepressant treatment on inhibitory avoidance behavior and amygdaloid beta-adrenoceptors in rats.
Topics: Adrenergic beta-Antagonists; Amygdala; Animals; Antidepressive Agents; Avoidance Learning; Desipramine; Fluoxetine; Injections, Intraventricular; Male; Muscarinic Antagonists; Phenelzine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Scopolamine | 1998 |
Effects of psychoactive drugs on temporal discrimination in rats.
Topics: Animals; Atropine; Clomipramine; Desipramine; Diazepam; Discrimination Learning; Discrimination, Psychological; Haloperidol; Male; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar; Scopolamine | 1997 |
Effects of Hypericum perforatum (St. John's wort) on passive avoidance in the rat: evaluation of potential neurochemical mechanisms underlying its antidepressant activity.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Brain Chemistry; Desipramine; Hypericum; Imipramine; Male; Muscarinic Antagonists; Norepinephrine; Paroxetine; Plant Extracts; Rats; Rats, Sprague-Dawley; Scopolamine; Serotonin | 2001 |
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine | 1964 |
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.
Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzazepines; Brain; Caffeine; Central Nervous System Stimulants; Cocaine; Desipramine; Dopamine Antagonists; Dronabinol; Enzyme Activation; Fluoxetine; Immunohistochemistry; Male; Mice; Mitogen-Activated Protein Kinases; Morphine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Scopolamine; Selective Serotonin Reuptake Inhibitors | 2004 |
Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Chromatography, High Pressure Liquid; Depression; Desipramine; Drug Interactions; Drug Synergism; Male; Mice; Motor Activity; Muscarinic Antagonists; Phosphodiesterase Inhibitors; Piperazines; Purines; Scopolamine; Sildenafil Citrate; Spectrophotometry, Ultraviolet; Sulfones; Swimming | 2012 |