desipramine has been researched along with protriptyline in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (74.36) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Altenbach, RJ; Black, LA; Brioni, JD; Carr, TL; Cowart, MD; Garrison, TR; Honore, P; Hsieh, GC; Manelli, AM; Marsh, KC; Strakhova, MI; Wensink, EJ; Wetter, JM | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Hollister, LE | 1 |
| Richelson, E | 1 |
| Levine, RM; Maickel, RP; Spaulding, JH; Zabik, JE | 1 |
| Hollander, CS; Tai, HH | 1 |
| Everitt, BJ | 1 |
| Korf, J; Meisch, JJ; van Wijk, M | 1 |
| Huey, LY; Janowsky, DS; Risch, SC | 1 |
| Bianchetti, G; Bonaccorsi, A; Chiodaroli, A; Franco, R; Garattini, S; Gomeni, R; Morselli, PL | 1 |
| Zwieten, PA | 1 |
| Detaevernier, MR; Dryon, L; Massart, DL | 1 |
| Bonaccorsi, A; Castelli, MG; Franco, R; Garattini, S; Morselli, PL | 1 |
| Schildkraut, JJ | 1 |
| Graf, U; van Schaik, N | 1 |
| Hwang, SA; Wilcox, GL | 1 |
| Chesher, GB; Jackson, DM; Starmer, GA | 1 |
| Chang, RS; Kling, P; Lotti, VJ | 1 |
| O'Donnell, JM; Seiden, LS | 1 |
| Audus, KL; Gordon, MA | 1 |
| Carter, RB; Leander, JD | 1 |
| Beierle, FA; Hubbard, RW | 1 |
| Isenberg, K; Livingston, RL; Wetzel, RD; Zucker, DK | 1 |
| Amsterdam, J; Brunswick, D; Mendels, J | 1 |
| Forker, AD; Marshall, JB | 1 |
| Lyskowksi, J; Nasrallah, HA; Schroeder, D | 1 |
| Friedel, RO | 1 |
| Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S | 1 |
| Crews, FT; Smith, CB | 1 |
| Esteban, S; García-Sevilla, JA; Lladó, J; Sastre-Coll, A | 1 |
4 review(s) available for desipramine and protriptyline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Tricyclic antidepressants (first of two parts).
Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; Depression; Desipramine; Doxepin; Humans; Imipramine; Kinetics; Neurotransmitter Agents; Nortriptyline; Protriptyline | 1978 |
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Imipramine; Nortriptyline; Protriptyline | 1980 |
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; Child; Depression; Desipramine; Doxepin; Electrocardiography; Hemodynamics; Humans; Hypotension; Imipramine; Kinetics; Middle Aged; Myocardium; Norepinephrine; Parasympatholytics; Protriptyline | 1982 |
35 other study(ies) available for desipramine and protriptyline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Desipramine; gamma-Aminobutyric Acid; Male; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Triazoles | 1988 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain.
Topics: Animals; Histamine H3 Antagonists; Naphthols; Norepinephrine Plasma Membrane Transport Proteins; Osteoarthritis; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Tricyclic antidepressants and histamine H1 receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic | 1979 |
Interactions of tricyclic antidepressant drugs with deprivation-induced fluid consumption by rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Drinking Behavior; Fenclonine; Imipramine; Male; Methyltyrosines; Nortriptyline; Protriptyline; Rats; Water Deprivation | 1977 |
Regulation of prostaglandin metabolism: activation of 15-hydroxyprostaglandin dehydrogenase by chlorpromazine and imipramine related drugs.
Topics: Alcohol Oxidoreductases; Amitriptyline; Animals; Chlorpromazine; Desipramine; Dibenzocycloheptenes; Enzyme Activation; Hydroxyprostaglandin Dehydrogenases; Imipramine; Kidney; Kinetics; NAD; Protriptyline; Swine | 1976 |
Effects of clomipramine and other inhibitors of monoamine uptake on the sexual behaviour of female rats and rhesus monkeys.
Topics: Animals; Clomipramine; Desipramine; Dibenzazepines; Estrogens; Female; Haplorhini; Macaca mulatta; Norepinephrine; Progesterone; Protriptyline; Rats; Serotonin; Sexual Behavior, Animal | 1977 |
Metabolism of 5-hydroxytryptamine and levels of tricyclic antidepressant drugs in rat brain after acute and chronic treatment.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Desipramine; Drug Administration Schedule; Imipramine; Male; Probenecid; Protriptyline; Rats; Serotonin | 1977 |
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Humans; Imipramine; Maprotiline; Protriptyline | 1979 |
Plasma concentrations and cardiotoxic effects of desipramine and protriptyline in the rat.
Topics: Animals; Chromatography, Gas; Desipramine; Dibenzocycloheptenes; Electrocardiography; Heart; Heart Rate; Male; Myocardium; Protriptyline; Rats; Time Factors | 1977 |
The reversal of clonidine-induced hypotension by protriptyline and desipramine.
Topics: Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dibenzocycloheptenes; Female; Male; Protriptyline | 1976 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
Relationships between chronotropic effect, 1-3H-noradrenaline uptake and tissue concentrations of desipramine, protripyline and doxepin in rat isolated atria.
Topics: Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Half-Life; Heart Rate; In Vitro Techniques; Kinetics; Myocardium; Norepinephrine; Protriptyline; Rats; Time Factors | 1976 |
Norepinephrine metabolism after short- and long-term administration of tricyclic antidepressant drugs and electroconvulsive shock.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression, Chemical; Desipramine; Electroshock; Imipramine; Norepinephrine; Protriptyline; Rats; Time Factors | 1975 |
Genotoxicity evaluation of five tricyclic antidepressants in the wing somatic mutation and recombination test in Drosophila melanogaster.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; DNA; Dose-Response Relationship, Drug; Drosophila melanogaster; Imipramine; Mutagenicity Tests; Nortriptyline; Protriptyline; Recombination, Genetic | 1991 |
Analgesic properties of intrathecally administered heterocyclic antidepressants.
Topics: Analgesics; Animals; Antidepressive Agents; Citalopram; Desipramine; Dibenzocycloheptenes; Fluoxetine; Injections, Spinal; Male; Mice; Propylamines; Protriptyline | 1987 |
Interaction of cannabis and general anaesthetic agents in mice.
Topics: Anesthesia, General; Animals; Cannabis; Desipramine; Dronabinol; Drug Synergism; Ethyl Ethers; Fenclonine; Hypothermia; Iproniazid; Male; Methyltyrosines; Mice; Mice, Inbred Strains; Pentobarbital; Phentolamine; Preanesthetic Medication; Propranolol; Protriptyline; Reserpine | 1974 |
Pre- and postsynaptic adrenergic activation by norepinephrine reuptake inhibitors in the field-stimulated rat vas deferens.
Topics: Amitriptyline; Animals; Chlorpromazine; Cocaine; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Male; Norepinephrine; Prazosin; Protriptyline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1981 |
Altered effects of desipramine on operant performance after 6-hydroxydopamine-induced depletion of brain dopamine or norepinephrine.
Topics: Animals; Brain; Conditioning, Operant; Desipramine; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Norepinephrine; Oxidopamine; Protriptyline; Rats; Rats, Inbred Strains | 1984 |
Effect of tricyclic antidepressant drugs on lymphocyte membrane structure.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Membrane; Cells, Cultured; Desipramine; Dose-Response Relationship, Drug; Fluorescent Dyes; Imipramine; Lymphocytes; Male; Mice; Nortriptyline; Protriptyline; Spleen; Temperature; Time Factors | 1984 |
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists | 1984 |
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline | 1983 |
Tricyclic antidepressants and delirium.
Topics: Adolescent; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Black People; Delirium; Desipramine; Female; Hospitalization; Humans; Male; Middle Aged; Protriptyline | 1983 |
TCA-induced mania: differences between switchers and nonswitchers.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Protriptyline | 1982 |
The relationship of therapeutic response to antidepressant plasma levels: an update.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive Disorder; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Patient Compliance; Protriptyline | 1982 |
Liquid-chromatographic analysis for common tricyclic antidepressant drugs and their metabolites in serum or plasma with the technicon "FAST-LC" system.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Protriptyline | 1981 |
The effects of antidepressants on the retention and metabolism of [3H]-norepinephrine in rat brain slices.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cocaine; Deamination; Desipramine; Dose-Response Relationship, Drug; In Vitro Techniques; Iprindole; Male; Norepinephrine; Nortriptyline; Protriptyline; Rats; Reserpine; Tritium | 1981 |
Activation and desensitization by cyclic antidepressant drugs of alpha2-autoreceptors, alpha2-heteroreceptors and 5-HT1A-autoreceptors regulating monamine synthesis in the rat brain in vivo.
Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Autoreceptors; Brain; Carboxy-Lyases; Cerebral Cortex; Desipramine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Hippocampus; Male; Norepinephrine; Protriptyline; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Tryptophan; Tyrosine; Zimeldine | 1999 |