desipramine has been researched along with prochlorperazine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiang, GH; Unger, SH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Frisk-Holmberg, M; van der Kleijn, E | 1 |
| Green, AL | 1 |
| Markham, CH | 1 |
| Mainard, F; Stephan, Y; Welin, L | 1 |
| Iriye, TT; Simmonds, FA | 2 |
| Oates, JA; Shand, DG | 1 |
1 review(s) available for desipramine and prochlorperazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
15 other study(ies) available for desipramine and prochlorperazine
| Article | Year |
|---|---|
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1972 |
Ionization constants and water solubilities of some aminoalkylphenothiazine tranquillizers and related compounds.
Topics: Amitriptyline; Chemical Phenomena; Chemistry; Chlorpromazine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Perphenazine; Phenothiazines; Prochlorperazine; Promethazine; Solubility; Thioridazine; Tranquilizing Agents; Trifluoperazine; Water | 1967 |
The "on-off" side effect of L-DOPA.
Topics: Age Factors; Amitriptyline; Aromatic Amino Acid Decarboxylase Inhibitors; Athetosis; Carbidopa; Catechol O-Methyltransferase Inhibitors; Chlordiazepoxide; Chorea; Desipramine; Diazepam; Dietary Proteins; Enzyme Inhibitors; Female; Humans; Imipramine; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Physical Exertion; Picolinic Acids; Prochlorperazine; Sex Factors; Stress, Psychological | 1974 |
[Binding to human serum proteins of drugs belonging to phenothiazine series, iminodibenzyle, thioxanthene and thiophenylpyridylamine].
Topics: Antidepressive Agents; Blood Proteins; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Chromatography, Gel; Desipramine; Dibenzazepines; Humans; Imipramine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Protein Binding; Spectrophotometry; Thiazines; Trimeprazine | 1971 |
Effect of tranquilizers and antidepressants on glycogen phosphorylase of rat brain.
Topics: Adenosine Monophosphate; Animals; Antidepressive Agents; Brain; Depression, Chemical; Desipramine; Dextroamphetamine; Female; Freezing; Glucosyltransferases; Iproniazid; Norepinephrine; Pargyline; Perphenazine; Phosphorylases; Prochlorperazine; Promazine; Promethazine; Rats; Receptors, Adrenergic; Reserpine; Tranquilizing Agents; Triflupromazine | 1971 |
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine | 1971 |
Possible involvement of glycogen phosphorylase of brain in the affective states.
Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Chlorpromazine; Depression; Desipramine; Drug Interactions; Female; Humans; Iproniazid; Pargyline; Phenothiazines; Phosphorylases; Prochlorperazine; Promazine; Promethazine; Rats; Receptors, Adrenergic; Reserpine; Stereoisomerism; Tranquilizing Agents | 1971 |