desipramine and procaine

desipramine has been researched along with procaine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19907 (41.18)18.7374
1990's1 (5.88)18.2507
2000's4 (23.53)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Duffy, EM; Jorgensen, WL1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
Ahman, M; Holmén, AG; Wan, H1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chiba, S1
Goodman, FR; Weiss, GB1
Kaniike, K; Kurogochi, Y1
Chang, CC; Chuang, ST1
Matsuo, S; Toda, N1
Edwards, WR1
Gerber, SH; Haass, M; Hagl, S; Heyer, C; Krüger, C; Kübler, W1

Other Studies

17 other study(ies) available for desipramine and procaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Procaine-induced positive chronotropic and inotropic responses of the isolated, blood-perfused dog atrium.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 225, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Desipramine; Dogs; Drug Interactions; Female; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nicotine; Norepinephrine; Procaine; Propranolol; Stimulation, Chemical; Tetrodotoxin; Tyramine

1977
Alteration of 5-hydroxytryptamine-14C efflux by nicotine in rat brain area slices.
    Neuropharmacology, 1973, Volume: 12, Issue:10

    Topics: Animals; Bicarbonates; Brain; Calcium; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Corpus Striatum; Desipramine; Hydrazines; Hydroxyindoleacetic Acid; Hypothalamus; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Nicotine; Potassium; Procaine; Rats; Serotonin; Sodium; Sodium Isotopes; Temperature; Time Factors

1973
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents

1972
Effects of desipramine and imipramine on the nerve, muscle and synaptic transmission of rat diaphragms.
    Neuropharmacology, 1972, Volume: 11, Issue:6

    Topics: Acetylcholine; Action Potentials; Animals; Axons; Chlorpromazine; Desipramine; Diaphragm; Electric Stimulation; Imipramine; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Neuromuscular Junction; Neurons; Phrenic Nerve; Procaine; Rats; Stimulation, Chemical; Synaptic Transmission

1972
The influence of desmethylimipramine on the chronotropic response to endogenous and exogenous noradrenaline in the isolated atria.
    British journal of pharmacology and chemotherapy, 1968, Volume: 32, Issue:3

    Topics: Animals; Cocaine; Desipramine; Drug Antagonism; Drug Synergism; Electric Stimulation; Female; Heart; Heart Atria; Heart Rate; Male; Muscle Contraction; Norepinephrine; Procaine; Rabbits; Stimulation, Chemical; Sympathetic Nervous System; Time Factors; Transducers; Tyramine

1968
Treatment of poisoning by anti-depressant drugs.
    British medical journal, 1967, Nov-11, Volume: 4, Issue:5575

    Topics: Brain Damage, Chronic; Desipramine; Humans; Hydrocortisone; Infant; Procaine; Thiopental; Urea

1967
Influence of Bretschneider's cardioplegia on norepinephrine release from isolated perfused guinea-pig hearts.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Desipramine; Dose-Response Relationship, Drug; Fever; Glucose; Guinea Pigs; Heart Arrest, Induced; Hypothermia; Ion Exchange; Mannitol; Myocardial Ischemia; Myocardium; Norepinephrine; Perfusion; Potassium Chloride; Procaine; Reperfusion; Temperature; Time Factors

1999