Compounds > desipramine

desipramine and pregnenolone carbonitrile

desipramine has been researched along with pregnenolone carbonitrile in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brookman, S; Kourounakis, P2

Other Studies

4 other study(ies) available for desipramine and pregnenolone carbonitrile

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Alterations induced in distribution and in vivo metabolism of imipramine by pregnenolone-16alpha-carbonitrile.
    Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:10

    Topics: Animals; Blood Proteins; Brain Chemistry; Chromatography, Gas; Desipramine; Drug Interactions; Female; Imipramine; Pregnenolone Carbonitrile; Protein Binding; Rats; Time Factors

1977
Effect of pregnenolone-16 alpha-carbonitrile on the biliary and urinary excretion of imipramine and some of its metabolites in rats.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:10

    Topics: Animals; Bile; Biotransformation; Chromatography, Thin Layer; Desipramine; Female; Imipramine; Oxidation-Reduction; Pregnenolone Carbonitrile; Rats

1982