desipramine has been researched along with piperidines in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (50.82) | 18.7374 |
| 1990's | 13 (21.31) | 18.2507 |
| 2000's | 11 (18.03) | 29.6817 |
| 2010's | 6 (9.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferris, RM; Tang, FL | 1 |
| Petersen, EN | 1 |
| Lehmann, K; Schmidt, J | 1 |
| Bechgaard, E; Buus Lassen, J; Lund, J; Søndergaard, I | 1 |
| Olsson, SO; Petersen, EN; Squires, RF | 1 |
| van Zwieten, PA | 1 |
| Baker, JC; Day, WA; Fuller, RW; Molloy, BB; Perry, KW | 1 |
| Lemaire, S; Rogers, C | 1 |
| Bowery, NG; Johnson, AM; Nelson, DR; Palmer, KJ; Pratt, GD | 1 |
| Marshall, IG; Prior, C; Wannan, G | 1 |
| Bakker, MH; Foster, AC; McKernan, RM; Wong, EH | 1 |
| Duckles, SP; Massamiri, T | 1 |
| Anderson, SN; Kacew, S; Ruben, Z | 1 |
| Insel, TR; Winslow, JT | 1 |
| Brøsen, K; Eshøj, O; Gram, LF; Mogensen, EF; Sindrup, SH | 1 |
| Brunello, N; Galimberti, R; Racagni, G; Riva, M; Rovescalli, AC | 1 |
| Nowak, G; Pawłowski, L | 1 |
| Göthert, M; Kollecker, P; Schlicker, E | 1 |
| Anwyl, R; Rowan, MJ | 1 |
| Richardson, KD; Urban, JH; Van de Kar, LD | 1 |
| Balsamo, A; Giorgi, I; Lapucci, A; Lucacchini, A; Macchia, B; Macchia, F; Martini, C; Rossi, A | 1 |
| Chinn, C; Weber, LJ | 1 |
| Green, KL | 1 |
| Finch, L | 1 |
| Fassina, G; Santi, R | 1 |
| Berstein, BM; Latimer, CN | 1 |
| Bouttier, D; Julou, L; Sigwald, J; Thomas, J | 1 |
| Chaplin, E; Eckhardt, SB; Hite, G; Maxwell, RE; Soares, JR | 1 |
| Scheel-Krüger, J | 1 |
| Leonard, BE; Tonge, SR | 1 |
| Dahl, LE; Dencker, SJ; le Fèvre Honoré, P; Lundin, L | 1 |
| Clausing, R; Göthert, M; Schlicker, E | 1 |
| Ashkenazi, R; Finberg, JP; Youdim, MB | 1 |
| Olpe, HR; Schellenberg, A | 1 |
| Carter, C; Fage, D; Nankai, M | 1 |
| Finberg, JP; Lavian, G; Youdim, MB | 1 |
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Misawa, M; Mori, T; Onodera, K; Suzuki, T; Tsuji, M | 1 |
| Kurz, T; Richardt, G; Schneider, I; Tölg, R | 1 |
| Liu, X; Onaka, T; Yagi, K | 1 |
| Cecil, A; Crites, G; Goldenberg, R; Knapp, RJ; Malatynska, E; Miller, C; Shuck, C; Watkins, J | 1 |
| FUKUCHI, G | 1 |
| BOFF, E; SCHECKEL, CL | 1 |
| SIEGLER, PE | 1 |
| LUDDEN, CT; PORTER, CC; STAVORSKI, JM; STONE, CA; TOTARO, JA | 1 |
| JACOBSON, J; URSILLO, RC | 1 |
| Biba, A; Christodoulou, A; Chrysikakou, S; Giannou, H; Kontis, D; Maillis, A; Pallidi, S; Rabavilas, A; Tsaltas, E | 1 |
| Gorzalka, BB; Hill, MN | 1 |
| Gorzalka, BB; Hill, MN; Hillard, CJ; Ho, WS; Sinopoli, KJ; Viau, V | 1 |
| Bourin, M; Chenu, F; Gardier, AM; Guiard, BP | 1 |
| Ben-Shabat, S; Fride, E; Gobshtis, N | 1 |
| Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM | 1 |
| Bächli, H; Borroni, E; Holsboer, F; Lutz, B; Marsicano, G; Monory, K; Steiner, MA; Wanisch, K; Wotjak, CT | 1 |
| Holsboer, F; Lutz, B; Marsicano, G; Nestler, EJ; Steiner, MA; Wotjak, CT | 1 |
| Gorzalka, BB; Hill, MN; Morrish, AC; Riebe, CJ | 1 |
| Griebel, G; Naimoli, VM; Overstreet, DH | 1 |
| Honda, S; Kawahara, R; Kawaura, K; Miki, R; Noguchi, T; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Dravid, SM; Gupta, SC; Morley, BJ; Pavuluri, R; Stairs, DJ; Yadav, R | 1 |
| Green, AI; Khokhar, JY | 1 |
| Dudka, J; Poleszak, E; Serefko, A; Stasiuk, W; Świąder, K; Szopa, A; Wlaź, P; Wyska, E | 1 |
| Chun, DY; Einolf, HJ; Gu, H; Sangana, R | 1 |
1 review(s) available for desipramine and piperidines
| Article | Year |
|---|---|
CURRENT STATUS OF DRUG TREATMENT IN THE DEPRESSIVE STATE.
Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Aspartic Acid; Benactyzine; Classification; Deanol; Depression; Desipramine; Humans; Imipramine; Isocarboxazid; Methylphenidate; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Pharmacology; Phenelzine; Phenmetrazine; Piperidines; Sympathomimetics; Toxicology; Tranylcypromine | 1964 |
2 trial(s) available for desipramine and piperidines
| Article | Year |
|---|---|
The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms.
Topics: Depression; Desipramine; Diabetic Neuropathies; Humans; Imipramine; Nervous System; Osmolar Concentration; Paroxetine; Piperidines; Serotonin Antagonists; Time Factors | 1990 |
Antidepressant effect of femoxetine and desipramine and relationship to the concentration of amine metabolites in cerebrospinal fluid. A double-blind evaluation.
Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Phenylacetates; Piperidines | 1982 |
58 other study(ies) available for desipramine and piperidines
| Article | Year |
|---|---|
Comparison of the effects of the isomers of amphetamine, methylphenidate and deoxypipradrol on the uptake of l-[3H]norepinephrine and [3H]dopamine by synaptic vesicles from rat whole brain, striatum and hypothalamus.
Topics: Amphetamine; Animals; Brain; Corpus Striatum; Desipramine; Dopamine; Energy Metabolism; Hypothalamus; In Vitro Techniques; Kinetics; Male; Methylphenidate; Norepinephrine; Piperidines; Rats; Reserpine; Stereoisomerism; Synaptic Vesicles; Temperature | 1979 |
The interaction of desipramine and the 5-HT uptake inhibitors femoxetine and paroxetine with the acute hypotensive effect of guanethidine in conscious spontaneously hypertensive rats.
Topics: Animals; Anisoles; Blood Pressure; Desipramine; Dioxolanes; Guanethidine; Heart Rate; Hypertension; Piperidines; Rats; Serotonin Antagonists; Time Factors | 1979 |
[Effect of psychotropic drugs on somatosensory evoked cortical potentials].
Topics: Animals; Anti-Anxiety Agents; Desipramine; Diazepam; Evoked Potentials; Female; Haloperidol; Hexobarbital; Medazepam; Piperidines; Rats; Somatosensory Cortex | 1979 |
Inhibition of 5-HT uptake into neurons and platelets in mice treated chronically with chlorimipramine and femoxetine.
Topics: Animals; Anisoles; Blood Platelets; Clomipramine; Desipramine; Female; Mice; Neurons; Nialamide; Piperidines; Serotonin; Serotonin Antagonists; Time Factors | 1979 |
Effects of 5HT uptake inhibitors on the pressor response to 5HT in the pithed rat. The significance of the 5HT blocking property.
Topics: Animals; Anisoles; Blood Pressure; Chlorpheniramine; Desipramine; Drug Synergism; Imipramine; Male; Muscle Contraction; Piperidines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes | 1977 |
Interaction between centrally acting hypotensive drugs and tricyclic antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Cats; Clonidine; Cocaine; Desipramine; Dioxanes; Drug Interactions; Ephedrine; Female; Male; Methyldopa; Piperidines; Reserpine | 1975 |
Biochemical pharmacology of some chlorinated 3-phenyl-piperidines in rats.
Topics: Amphetamine; Animals; Brain Chemistry; Desipramine; Half-Life; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Piperidines; Rats; Serotonin; Time Factors | 1975 |
Characterization of [3H]desmethylimipramine binding in bovine adrenal medulla: interactions with sigma- and (or) phencyclidine-receptor ligands.
Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Desipramine; Dextromethorphan; Dizocilpine Maleate; Phenazocine; Phencyclidine; Piperidines; Potassium Chloride; Receptors, Opioid, delta; Receptors, Phencyclidine; Tranquilizing Agents | 1992 |
Effect of paroxetine, a selective 5-hydroxytryptamine uptake inhibitor, on beta-adrenoceptors in rat brain: autoradiographic and functional studies.
Topics: Adrenergic beta-Antagonists; Amitriptyline; Animals; Autoradiography; Brain Chemistry; Cyclic AMP; Desipramine; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Membranes; Paroxetine; Pindolol; Piperidines; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin Antagonists | 1991 |
Alpha-adrenoceptor blocking properties of vesamicol.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Vas Deferens | 1991 |
[3H]MK-801 binding to N-methyl-D-aspartate receptors solubilized from rat brain: effects of glycine site ligands, polyamines, ifenprodil, and desipramine.
Topics: Animals; Binding Sites; Brain; Chromatography, Gel; Desipramine; Dizocilpine Maleate; Glycine; Ligands; Male; Piperidines; Polyamines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Solubility; Tritium | 1991 |
Interactions of sigma and phencyclidine receptor ligands with the norepinephrine uptake carrier in both rat brain and rat tail artery.
Topics: Animals; Biological Transport; Brain; Desipramine; Dizocilpine Maleate; Male; Norepinephrine; Phenazocine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Tail; Vasoconstriction | 1991 |
Changes in saccharide and phospholipid content associated with drug storage in cultured rabbit aorta muscle cells.
Topics: Amines; Amiodarone; Animals; Anti-Arrhythmia Agents; Aorta; Cells, Cultured; Chloroquine; Desipramine; Ethylenediamines; Kinetics; Microscopy, Electron; Monosaccharides; Muscle, Smooth, Vascular; Phospholipids; Piperidines; Rabbits; Tilorone | 1991 |
Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups.
Topics: Animals; Body Temperature; Catecholamines; Citalopram; Clomipramine; Desipramine; Flumazenil; Mazindol; Motor Activity; Naltrexone; Nortriptyline; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stress, Psychological; Ultrasonics; Vocalization, Animal | 1990 |
Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment.
Topics: Aging; Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Hydroxyindoleacetic Acid; Imipramine; Ketanserin; Kinetics; Male; Paroxetine; Piperidines; Prazosin; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Time Factors | 1988 |
Biochemical and pharmacological tests for the prediction of ability of monoamine uptake blockers to inhibit the uptake of noradrenaline in-vivo: the effects of desipramine, maprotiline, femoxetine and citalopram.
Topics: Animals; Apomorphine; Body Temperature; Brain; Citalopram; Desipramine; Male; Maprotiline; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Piperidines; Propylamines; Reserpine; Serotonin Antagonists; Thyrotropin-Releasing Hormone; Tyramine | 1987 |
Receptor-mediated effects of serotonin and 5-methoxytryptamine on noradrenaline release in the rat vena cava and in the heart of the pithed rat.
Topics: 5-Methoxytryptamine; Animals; Blood Pressure; Decerebrate State; Desipramine; Electric Stimulation; Heart; Heart Rate; Ketanserin; Male; Myocardium; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Tryptamines; Vagotomy; Vena Cava, Inferior | 1986 |
The effect of prolonged treatment with tricyclic antidepressants on the actions of 5-hydroxytryptamine in the hippocampal slice of the rat.
Topics: Animals; Cyproheptadine; Desipramine; Evoked Potentials; Hippocampus; Imipramine; In Vitro Techniques; Ketanserin; Male; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Serotonin and norepinephrine-dependent effects of fenfluramine on plasma renin activity in conscious male rats.
Topics: Animals; Blood Pressure; Desipramine; Dose-Response Relationship, Drug; Fenclonine; Fenfluramine; Fluoxetine; Heart Rate; Male; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Renin; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan | 1985 |
3-[(2-ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Desipramine; Dopamine; Drug Evaluation, Preclinical; Ethyl Ethers; Hypothermia; Indicators and Reagents; Mice; Norepinephrine; Phenyl Ethers; Piperidines; Reserpine; Seizures; Serotonin; Structure-Activity Relationship; Synaptosomes; Viloxazine | 1987 |
The actions of several psychoactive agents upon the muscarinic mechanisms in the superior cervical ganglion of the cat.
Topics: Alkynes; Animals; Atropine; Carbamates; Cats; Desipramine; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Ganglia, Autonomic; Ganglia, Spinal; Heart Rate; Hexamethonium Compounds; Hydrazines; Injections, Intra-Arterial; Male; Methylphenidate; Muscle Contraction; Nictitating Membrane; Nortriptyline; Parasympathetic Nervous System; Parasympathomimetics; Pargyline; Piperidines; Quaternary Ammonium Compounds | 1974 |
Role of endogenous catecholamines in the anti-inflammatory activity of alpha-adrenoceptor blocking agents.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Capillary Permeability; Catecholamines; Cocaine; Desipramine; Dioxins; Epinephrine; Female; Methyltyrosines; Mice; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Phentolamine; Piperidines; Rats; Serum Albumin; Uterus; Yohimbine | 1974 |
The cardiovascular effects of intraventricular clonidine and Bay 1470 in conscious hypertensive cats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dioxanes; Dopamine Antagonists; Haloperidol; Heart Rate; Hemodynamics; Hypertension, Renal; Phentolamine; Piperidines; Thiazines; Time Factors; Xylazine | 1974 |
Anorexigenic drugs and lipid mobilisation.
Topics: Amitriptyline; Animals; Appetite Depressants; Chlorphentermine; Desipramine; Dextroamphetamine; Fatty Acids; Imipramine; Lipid Metabolism; Methylphenidate; Piperidines; Rats | 1965 |
Behavioral facilitation: the interaction of imipramine and desipra- mine with amphetamine, alpha-pipradrol, methylphenidate, and thozalinone.
Topics: Amphetamine; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Desipramine; Drug Synergism; Imipramine; Male; Methylphenidate; Oxazoles; Piperidines; Rats; Stimulation, Chemical | 1968 |
[Therapy of hypersomnia].
Topics: Amphetamine; Animals; Antidepressive Agents; Appetite Depressants; Bemegride; Caffeine; Cats; Central Nervous System Stimulants; Chlorphentermine; Desipramine; Electroencephalography; Ephedrine; Glycolates; Humans; Hydroxybutyrates; Imipramine; Mice; Narcolepsy; Pemoline; Phentermine; Piperidines; Rabbits; Rats; Sleep Wake Disorders; Strychnine; Sympathomimetics | 1967 |
Conformational similarities between molecular models of phenethylamine and of potent inhibitors of the uptake of tritiated norepinephrine by adrenergic nerves in rabbit aorta.
Topics: Animals; Antidepressive Agents; Aorta; Chemical Phenomena; Chemistry; Cocaine; Desipramine; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methylphenidate; Models, Structural; Norepinephrine; Nortriptyline; Phenethylamines; Piperidines; Rabbits; Sensory Receptor Cells; Sympathetic Nervous System; Tritium; Tyramine | 1970 |
Studies on the accumulation of O-methylated dopamine and noradrenaline in the rat brain following various neuroleptics, thymoleptics and aceperone.
Topics: Acetamides; Animals; Antidepressive Agents; Benzimidazoles; Brain; Brain Chemistry; Butyrophenones; Chlorpromazine; Chlorprothixene; Desipramine; Dopamine; Imipramine; Ketones; Male; Methylation; Norepinephrine; Normetanephrine; Pargyline; Piperidines; Rats; Stimulation, Chemical; Tranquilizing Agents; Tyramine | 1972 |
Interaction of phencyclidine with drugs affecting noradrenaline metabolism in the rat brain.
Topics: Anesthetics; Animals; Brain; Brain Chemistry; Desipramine; Drug Antagonism; Drug Synergism; Norepinephrine; Normetanephrine; Phencyclidine; Piperidines; Rats; Tetrabenazine | 1972 |
Acute or chronic changes of noradrenergic transmission do not affect the alpha-adrenoceptor-mediated inhibition of 3H-serotonin release in the cerebral cortex.
Topics: Animals; Cerebral Cortex; Desipramine; Drug Interactions; Guanethidine; Hydroxydopamines; Male; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synaptic Transmission | 1982 |
Effects of LM 5008, a selective inhibitor of 5-hydroxytryptamine uptake, on blood pressure and responses to sympathomimetic amines.
Topics: Angiotensin II; Animals; Blood Pressure; Clomipramine; Desipramine; Drug Interactions; Female; Male; Norepinephrine; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Serotonin Antagonists; Species Specificity; Sympathomimetics; Tyramine | 1983 |
The sensitivity of cortical neurons to serotonin: effect of chronic treatment with antidepressants, serotonin-uptake inhibitors and monoamine-oxidase-blocking drugs.
Topics: Animals; Benzofurans; Cerebral Cortex; Clomipramine; Clorgyline; Desipramine; Electric Conductivity; gamma-Aminobutyric Acid; Male; Monoamine Oxidase Inhibitors; Neurons; Piperidines; Rats; Selegiline; Serotonin; Serotonin Antagonists | 1981 |
NMDA receptor subtype selectivity: eliprodil, polyamine spider toxins, dextromethorphan, and desipramine selectively block NMDA-evoked striatal acetylcholine but not spermidine release.
Topics: Acetylcholine; Animals; Corpus Striatum; Desipramine; Dextromethorphan; Indoleacetic Acids; N-Methylaspartate; Phenols; Phenylacetates; Piperidines; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spider Venoms | 1995 |
The advent of a new generation of monoamine oxidase inhibitor antidepressants: pharmacologic studies with moclobemide and brofaromine.
Topics: Animals; Antidepressive Agents; Benzamides; Blood Pressure; Clorgyline; Desipramine; Heart Rate; Kidney; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1993 |
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Generalization of D-, L- and DL-chlorpheniramine and zolantidine to the discriminative stimulus effects of cocaine and methamphetamine.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzothiazoles; Chlorpheniramine; Clomipramine; Cocaine; Desipramine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Methamphetamine; Middle Aged; Phenoxypropanolamines; Piperazines; Piperidines; Rats; Rats, Inbred F344; Thiazoles | 1997 |
Alpha 1-adrenergic receptor-mediated increase in the mass of phosphatidic acid and 1,2-diacylglycerol in ischemic rat heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Chromatography, Thin Layer; Desipramine; Diacylglycerol Kinase; Diglycerides; Estrenes; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Norepinephrine; Perfusion; Phosphatidic Acids; Piperidines; Prazosin; Propranolol; Pyrrolidinones; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Time Factors; Type C Phospholipases | 1999 |
Facilitation of Ca2+ store-dependent noradrenaline release after an N-methyl-D-aspartate receptor antagonist in the rat supraoptic nucleus.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Desipramine; Excitatory Amino Acid Antagonists; Male; Microdialysis; N-Methylaspartate; Norepinephrine; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus; Tetrodotoxin | 2001 |
Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model.
Topics: Animals; Antidepressive Agents; Competitive Behavior; Desipramine; Diazepam; Dioxoles; Dose-Response Relationship, Drug; Fluoxetine; Injections, Intraperitoneal; Male; Maze Learning; Models, Animal; Nootropic Agents; Piperidines; Piracetam; Pyrrolidinones; Rats; Rats, Sprague-Dawley | 2002 |
[DRUGS ACTING ON THE NERVOUS SYSTEM. (2). WITH SPECIAL REFERENCE TO TRANQUILIZERS AND ANTIDEPRESSIVE AGENTS].
Topics: Amides; Amitriptyline; Antidepressive Agents; Benactyzine; Chemical Phenomena; Chemistry; Chlordiazepoxide; Desipramine; Diazepam; Haloperidol; Humans; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Isocarboxazid; Meprobamate; Methylphenidate; Monoamine Oxidase Inhibitors; Nervous System; Nialamide; Pharmacology; Phenelzine; Piperidines; Tranquilizing Agents; Tranylcypromine; Tryptamines | 1963 |
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine | 1964 |
ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Electrophysiology; Guanethidine; Imipramine; Metaraminol; Methylphenidate; Mice; Myocardium; Nictitating Membrane; Norepinephrine; Pharmacology; Piperidines; Promazine; Research; Reserpine; Tripelennamine; Tyrosine | 1964 |
POTENTIATION OF NOREPINEPHRINE IN THE ISOLATED VAS DEFERENS OF THE RAT BY SOME CNS STIMULANTS AND ANTIDEPRESSANTS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Humans; Imipramine; Male; Methylphenidate; Norepinephrine; Pharmacology; Phenmetrazine; Piperidines; Rats; Research; Tranquilizing Agents; Vas Deferens | 1965 |
Reinforced spatial alternation as an animal model of obsessive-compulsive disorder (OCD): investigation of 5-HT2C and 5-HT1D receptor involvement in OCD pathophysiology.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Desipramine; Diazepam; Disease Models, Animal; Fluoxetine; Indoles; Male; Maze Learning; Obsessive-Compulsive Disorder; Piperazines; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptamines | 2005 |
Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arachidonic Acids; Desipramine; Dose-Response Relationship, Drug; Dronabinol; Male; Motor Activity; Oleic Acids; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Swimming | 2005 |
Involvement of the endocannabinoid system in the ability of long-term tricyclic antidepressant treatment to suppress stress-induced activation of the hypothalamic-pituitary-adrenal axis.
Topics: Animals; Antidepressive Agents, Tricyclic; Cannabinoid Receptor Modulators; Cortisone; Depressive Disorder, Major; Desipramine; Disease Models, Animal; Drug Administration Schedule; Endocannabinoids; Gene Expression Regulation; Hippocampus; Hypothalamo-Hypophyseal System; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Stress, Psychological; Up-Regulation | 2006 |
Antidepressant-like activity of selective serotonin reuptake inhibitors combined with a NK1 receptor antagonist in the mouse forced swimming test.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Depressive Disorder; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Escape Reaction; Male; Mice; Neurokinin-1 Receptor Antagonists; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming; Tetrazoles | 2006 |
Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectiveness.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Desipramine; Female; Fluoxetine; Maze Learning; Mice; Motor Activity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Swimming; Time Factors; Weight Gain | 2007 |
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine | 2007 |
Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice.
Topics: Adaptation, Psychological; Animals; Biogenic Monoamines; Brain-Derived Neurotrophic Factor; Desipramine; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; RNA, Messenger; Signal Transduction; Stress, Psychological; Swimming; Vesicular Glutamate Transport Protein 1 | 2008 |
Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice.
Topics: Adaptation, Psychological; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Desipramine; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction; Statistics, Nonparametric; Stress, Psychological; Swimming; Time Factors | 2008 |
Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: role of gender and noradrenergic transmission.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Cannabinoids; Desipramine; Dronabinol; Female; Male; Norepinephrine; Piperidines; Prazosin; Propranolol; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sex Characteristics; Substance Withdrawal Syndrome; Swimming; Synaptic Transmission | 2009 |
Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression.
Topics: Animals; Antidepressive Agents; Benzamides; Depression; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Social Behavior; Swimming | 2010 |
Effect of tipepidine with novel antidepressant-like action on c-fos-like protein expression in rat brain.
Topics: Animals; Antidepressive Agents; Brain; Desipramine; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Swimming | 2013 |
Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Dendritic Spines; Desipramine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamate Dehydrogenase; Hippocampus; Mice; Mice, Knockout; Motor Activity; Neurons; Phenols; Piperidines; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Signal Transduction; Sodium Channel Blockers; Swimming; Tetrodotoxin | 2015 |
Effects of iloperidone, combined with desipramine, on alcohol drinking in the Syrian golden hamster.
Topics: Adrenergic Uptake Inhibitors; Alcohol Drinking; Animals; Antipsychotic Agents; Clozapine; Cricetinae; Desipramine; Isoxazoles; Male; Mesocricetus; Piperidines | 2016 |
Influence of the selective antagonist of the NR2B subunit of the NMDA receptor, traxoprodil, on the antidepressant-like activity of desipramine, paroxetine, milnacipran, and bupropion in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain; Bupropion; Chromatography, High Pressure Liquid; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Male; Mice; Milnacipran; Motor Activity; Paroxetine; Piperidines; Receptors, N-Methyl-D-Aspartate | 2017 |
Evaluation of Clinical Drug Interaction Potential of Clofazimine Using Static and Dynamic Modeling Approaches.
Topics: Antitubercular Agents; Area Under Curve; Carbamates; Clofazimine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Humans; Midazolam; Models, Biological; Piperidines; Tuberculosis, Multidrug-Resistant | 2018 |