desipramine has been researched along with pindolol in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (25.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 13 (32.50) | 29.6817 |
| 2010's | 13 (32.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Caron, G; Ermondi, G | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Akamatsu, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Goetz, GH; Philippe, L; Shapiro, MJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Harden, TK; Molinoff, PB; Sporn, JR; Wolfe, BB | 1 |
| Endoh, M | 1 |
| Bowery, NG; Johnson, AM; Nelson, DR; Palmer, KJ; Pratt, GD | 1 |
| Kostowski, W; Pałejko, W; Płaźnik, A; Stefański, R | 1 |
| Areso, P; Frazer, A; Gambarana, C; Hensler, JG; Ordway, GA | 1 |
| Broadley, KJ; Williamson, KL | 1 |
| Gonzalez-Brito, A; Guerrero, JM; Jones, DJ; Menendez-Pelaez, A; Reiter, RJ; Santana, C | 1 |
| Frazer, A; Gambarana, C; Ordway, GA | 1 |
| Chiu, A; Li, PP; Sibony, D; Warsh, JJ | 1 |
| Beer, M; Hacker, S; Poat, J; Stahl, SM | 1 |
| Frangakis, MV; Kimelberg, HK | 1 |
| Okada, F; Tokumitsu, Y; Ui, M | 1 |
| Minneman, KP; Molinoff, PB; Wolfe, BB | 1 |
| Bergeron, R; Blier, P; de Montigny, C | 1 |
| Aksu, F; Belzung, C; Yalcin, I | 1 |
1 review(s) available for desipramine and pindolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
39 other study(ies) available for desipramine and pindolol
| Article | Year |
|---|---|
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides.
Topics: | 2014 |
Regulation of beta-adrenergic receptors in the cerebral cortex.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Cyclic AMP; Desipramine; Hydroxydopamines; In Vitro Techniques; Male; Pindolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1978 |
Effects of dopamine on sinus rate and ventricular contractile force of the dog heart in vitro and in vivo.
Topics: Animals; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Female; Heart Rate; In Vitro Techniques; Injections, Intravenous; Male; Myocardial Contraction; Norepinephrine; Papillary Muscles; Phenoxybenzamine; Pindolol; Reserpine; Sinoatrial Node | 1975 |
Effect of paroxetine, a selective 5-hydroxytryptamine uptake inhibitor, on beta-adrenoceptors in rat brain: autoradiographic and functional studies.
Topics: Adrenergic beta-Antagonists; Amitriptyline; Animals; Autoradiography; Brain Chemistry; Cyclic AMP; Desipramine; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Membranes; Paroxetine; Pindolol; Piperidines; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin Antagonists | 1991 |
Serotonergic mechanisms in the nucleus accumbens affected by chronic desipramine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Chromans; Desipramine; Dose-Response Relationship, Drug; Methysergide; Microinjections; Nucleus Accumbens; Pindolol; Quipazine; Rats; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Serotonergic neurons do not influence the regulation of beta adrenoceptors induced by either desipramine or isoproterenol.
Topics: 5,7-Dihydroxytryptamine; Animals; Desipramine; Dihydroalprenolol; Isoproterenol; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin | 1991 |
Do both adrenaline and noradrenaline stimulate cardiac alpha-adrenoceptors to induce positive inotropy of rat atria?
Topics: Animals; Cocaine; Desipramine; Dibenzylchlorethamine; Epinephrine; Haloperidol; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Timolol | 1989 |
Darkness-induced changes in noradrenergic input determine the 24 hour variation in beta-adrenergic receptor density in the rat pineal gland: in vivo physiological and pharmacological evidence.
Topics: Animals; Circadian Rhythm; Darkness; Desipramine; Ganglia, Sympathetic; Isoproterenol; Male; Norepinephrine; Pindolol; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1988 |
Quantitative autoradiography of central beta adrenoceptor subtypes: comparison of the effects of chronic treatment with desipramine or centrally administered l-isoproterenol.
Topics: Animals; Autoradiography; Brain Chemistry; Desipramine; Isoproterenol; Male; Norepinephrine; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1988 |
Assessment of rat brain alpha 1-adrenoceptor binding and activation of inositol phospholipid turnover following chronic imipramine treatment.
Topics: Animals; Cerebral Cortex; Desipramine; Imipramine; In Vitro Techniques; Inositol Phosphates; Iodocyanopindolol; Norepinephrine; Pindolol; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Sugar Phosphates | 1988 |
Independent regulation of beta 1- and beta 2-adrenoceptors.
Topics: Adrenergic beta-Agonists; Animals; Cerebral Cortex; Clenbuterol; Desipramine; In Vitro Techniques; Iodine Radioisotopes; Male; Pindolol; Prenalterol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Xamoterol | 1987 |
Desensitization of beta-receptors on primary astrocyte cultures by norepinephrine but not by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Astrocytes; Cells, Cultured; Cyclic AMP; Desipramine; Iodocyanopindolol; Norepinephrine; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Desensitization of beta-adrenergic receptor-coupled adenylate cyclase in cerebral cortex after in vivo treatment of rats with desipramine.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Desipramine; Drug Tolerance; Enzyme Activation; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1986 |
Selective changes in the density of beta 1-adrenergic receptors in rat striatum following chronic drug treatment and adrenalectomy.
Topics: Adrenalectomy; Animals; Caudate Nucleus; Corpus Striatum; Desipramine; Male; Pargyline; Pindolol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1982 |
Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Buspirone; Depressive Disorder; Desipramine; Drug Synergism; Female; Fluvoxamine; Humans; Male; Pindolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Trimipramine | 1997 |
Effects of desipramine and tramadol in a chronic mild stress model in mice are altered by yohimbine but not by pindolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Chronic Disease; Desipramine; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Motor Activity; Pindolol; Stress, Physiological; Tramadol; Yohimbine | 2005 |