desipramine and phenylephrine

desipramine has been researched along with phenylephrine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199018 (58.06)18.7374
1990's5 (16.13)18.2507
2000's6 (19.35)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Endoh, M; Shimizu, T; Yanagisawa, T1
Chiba, S1
Ekström, J1
Badia, A; Sallés, J; Vila, E1
Lacroix, JS; Lundberg, JM1
Moulds, RF; Stevens, MJ1
Arendt, J; Checkley, SA; Corn, TH; Franey, C; Glass, IB; Thompson, C1
Arendt, J; Checkley, SA; Corn, T; English, J; Franey, C; Mezey, G; Thompson, C1
Booth, DA1
Fulton, RW; Masucci, FD; Pals, DT1
Pals, DT1
Leclair, MF; Valette, G1
Aghajanian, GK; Gallager, DW; Menkes, DB1
Aghajanian, GK; Davis, M; Gallager, DW; Kehne, JH; Menkes, DB1
Kanazawa, Y; Kitada, Y; Miyauchi, T; Nakamichi, H; Satoh, S1
Maze, M; Smith, CM; Spiss, CK1
Kitada, Y; Kosasa, T; Miyauchi, T; Satoh, S1
MacDonald, E1
Checkley, S; Shur, E1
Cosentino, M; De Ponti, F; Frigo, GM; Lecchini, S; Marcoli, M; Marino, F1
Fawcett, JP; Menkes, DB; Patel, PP1
Chiao, PC; Corbett, JR; del Rosario, RB; Gildersleeve, DL; Raffel, DM; Schwaiger, M; Wieland, DM1
Dailey, JW; Jobe, PC; Steenbergen, JL; Yan, QS1
Gerevich, Z; Lendvai, B; Santha, E1
Hopwood, SE; Stamford, JA1
Barrento, C; Lima, BS; Mota-Filipe, H; Pinto, R1
Schoffelmeer, AN; van Gaalen, MM; van Koten, R; Vanderschuren, LJ1
Bengel, FM; Dannals, RF; Fox, JJ; Green, G; Holt, DP; Pomper, M; Tipre, DN; Yu, J1
Pattij, T; Schetters, D; Schoffelmeer, AN; van Gaalen, MM1
Brock, JA; McLachlan, EM; Tripovic, D1

Other Studies

31 other study(ies) available for desipramine and phenylephrine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Characterization of adrenoceptors mediating positive inotropic responses in the ventricular myocardium of the dog.
    British journal of pharmacology, 1978, Volume: 64, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Clonidine; Desipramine; Dogs; Female; Heart Ventricles; Male; Methoxamine; Myocardial Contraction; Papaverine; Papillary Muscles; Phenylephrine; Phosphodiesterase Inhibitors; Receptors, Adrenergic; Reserpine; Sinoatrial Node; Stimulation, Chemical; Temperature

1978
Mechanism of chronotropic and inotropic effects of phenylephrine.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:4

    Topics: Alprenolol; Animals; Atropine; Depression, Chemical; Desipramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Heart Ventricles; In Vitro Techniques; Injections, Intra-Arterial; Levobunolol; Methoxamine; Myocardial Contraction; Phentolamine; Phenylephrine; Stimulation, Chemical; Tetrodotoxin

1977
Supersensitivity of the rat urinary bladder following "chemical sympathectomy".
    Acta pharmacologica et toxicologica, 1979, Volume: 44, Issue:5

    Topics: Animals; Cocaine; Denervation; Desipramine; Epinephrine; Hydroxydopamines; Isoproterenol; Male; Methacholine Compounds; Muscle, Smooth; Norepinephrine; Organ Size; Parasympathomimetics; Phenylephrine; Pressure; Rats; Sympathetic Nervous System; Sympathomimetics; Urinary Bladder

1979
Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:3

    Topics: Animals; Antidepressive Agents; Cocaine; Desipramine; Electric Stimulation; Male; Mianserin; Muscle Contraction; Muscles; Nomifensine; Normetanephrine; Nortriptyline; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine

1990
Sympathetic vascular control of the pig nasal mucosa: adrenoceptor mechanisms in blood flow and volume control.
    British journal of pharmacology, 1989, Volume: 97, Issue:4

    Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Desipramine; Dioxanes; Electric Stimulation; Female; Idazoxan; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Phenylephrine; Prazosin; Quinoxalines; Receptors, Adrenergic; Regional Blood Flow; Rheology; Swine; Sympathetic Nervous System

1989
Factors determining alpha-adrenoceptor-mediated responses of human digital arteries and metacarpal veins.
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: Desipramine; Dose-Response Relationship, Drug; Fingers; Humans; Hydrocortisone; Metacarpus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic, alpha; Yohimbine

1985
Neuroendocrine and other studies of the mechanism of antidepressant action of desipramine.
    Ciba Foundation symposium, 1986, Volume: 123

    Topics: Animals; Blood Pressure; Clonidine; Depression; Desipramine; Growth Hormone; Humans; Melatonin; Phenylephrine; Pupil; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Secretory Rate; Synaptic Transmission; Tyramine

1986
The effect of desipramine upon melatonin and cortisol secretion in depressed and normal subjects.
    The British journal of psychiatry : the journal of mental science, 1985, Volume: 147

    Topics: Adolescent; Adult; Depressive Disorder; Desipramine; Female; Humans; Hydrocortisone; Male; Melatonin; Phenylephrine; Pupil; Time Factors; Tyramine

1985
Mechanism of action of norepinephrine in eliciting an eating response on injection into the rat hypothalamus.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 160, Issue:2

    Topics: Amphetamine; Angiotensin II; Animals; Behavior, Animal; Brain Chemistry; Desipramine; Drinking; Eating; Ephedrine; Epinephrine; Histamine; Hypothalamus; Injections; Isoproterenol; Male; Methods; Norepinephrine; Normetanephrine; Octopamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Propranolol; Rats; Stimulation, Chemical; Tritium; Tyramine

1968
Angiotensin, cocaine and desipramine: comparison of effects on blood pressure responses to norepinephrine, tyramine and phenylephrine in the pithed rat.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 162, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Cocaine; Desipramine; Drug Synergism; Heart; Myocardium; Norepinephrine; Phenylephrine; Rats; Spleen; Stimulation, Chemical; Tritium; Tyramine

1968
Effect of bretylium tosylate on angiotensin pressor responses in the pithed rat.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 173, Issue:2

    Topics: Angiotensin II; Animals; Blood Pressure; Bretylium Compounds; Desipramine; Norepinephrine; Phenylephrine; Rats

1968
[Role of the phenomenon of uptake on the sensitizing action of metabolic inhibitors on the response of isolated intestines of rats to the effects of sympathomimetics].
    Biochemical pharmacology, 1972, Jul-01, Volume: 21, Issue:13

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium; Cyanides; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Duodenum; In Vitro Techniques; Intestinal Mucosa; Isoproterenol; Malonates; Monoamine Oxidase Inhibitors; Nialamide; Norepinephrine; Phenylephrine; Rats; Receptors, Cholinergic; Receptors, Drug; Reserpine; Sodium; Sympathomimetics; Tranylcypromine

1972
Chronic antidepressant treatment enhances agonist affinity of brain alpha 1-adrenoceptors.
    European journal of pharmacology, 1983, Jan-28, Volume: 87, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Binding, Competitive; Brain; Desipramine; Iprindole; Kinetics; Male; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thalamus

1983
Functional supersensitivity of CNS alpha 1-adrenoceptors following chronic antidepressant treatment.
    Life sciences, 1983, Jul-11, Volume: 33, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Binding Sites; Desipramine; Hydroxydopamines; Iprindole; Male; Norepinephrine; Oxidopamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex, Acoustic

1983
Involvement of alpha- and beta 1-adrenergic mechanisms in the immobility-reducing action of desipramine in the forced swimming test.
    Neuropharmacology, 1983, Volume: 22, Issue:9

    Topics: Animals; Atenolol; Brain; Desipramine; Drug Interactions; Helplessness, Learned; Humans; Isoproterenol; Male; Motor Activity; Phenoxybenzamine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Swimming

1983
Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:9

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Desipramine; Dogs; Drug Interactions; Epinephrine; Female; Halothane; Heart Rate; Imipramine; Norepinephrine; Phenylephrine

1984
Further studies on the suppressing effect of isoproterenol on the immobility-reducing action of desipramine in the forced swimming test.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:4

    Topics: Animals; Atenolol; Clonidine; Desipramine; Isoproterenol; Male; Motor Activity; Phenylephrine; Rats; Rats, Inbred Strains; Swimming; Yohimbine

1983
Cardiovascular effects of copper in pithed rats.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:1

    Topics: Animals; Blood Pressure; Copper; Desipramine; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Hemolysis; Male; Phentolamine; Phenylephrine; Rats; Rats, Inbred Strains; Spinal Cord

1984
Pupil studies in depressed patients: an investigation of the mechanism of action of desipramine.
    The British journal of psychiatry : the journal of mental science, 1982, Volume: 140

    Topics: Adult; Aged; Depressive Disorder; Desipramine; Drug Synergism; Female; Humans; Male; Middle Aged; Phenylephrine; Pilocarpine; Pupil; Tyramine

1982
Effect of desipramine-induced blockade of neuronal uptake mechanisms on adrenoceptor-mediated responses in the guinea-pig colon.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:5

    Topics: Acetylcholine; Adrenergic Agonists; Animals; Clonidine; Colon; Desipramine; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Neurons; Norepinephrine; Peristalsis; Phenylephrine; Receptors, Adrenergic; Xylazine

1994
Antidepressant treatment and chemical sympathectomy fail to modulate alpha 1-adrenoceptor sensitivity in mouse eye.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Administration, Topical; Amitriptyline; Animals; Antidepressive Agents; Benzamides; Desipramine; Down-Regulation; Fluoxetine; Injections, Intraperitoneal; Male; Methoxamine; Mice; Moclobemide; Oxidopamine; Phentolamine; Phenylephrine; Prazosin; Pupil; Receptors, Adrenergic, alpha-1; Sympathectomy, Chemical; Time Factors

1993
Clinical evaluation of carbon-11-phenylephrine: MAO-sensitive marker of cardiac sympathetic neurons.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:12

    Topics: Adult; Carbon Radioisotopes; Desipramine; Ephedrine; Female; Heart; Humans; Male; Middle Aged; Monoamine Oxidase; Phenylephrine; Sympathetic Nervous System; Tomography, Emission-Computed

1996
Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study.
    Brain research, 1998, Jan-12, Volume: 780, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Desipramine; Drug Interactions; Epilepsy; Female; Fluoxetine; Idazoxan; Methoxamine; Microinjections; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Superior Colliculi; Synaptic Transmission

1998
Low temperature prevents potentiation of norepinephrine release by phenylephrine.
    Neurochemistry international, 2001, Volume: 38, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Calcium; Cell Membrane; Cold Temperature; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Exocytosis; Extracellular Space; Guinea Pigs; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Prazosin; Vas Deferens

2001
Noradrenergic modulation of serotonin release in rat dorsal and median raphé nuclei via alpha(1) and alpha(2A) adrenoceptors.
    Neuropharmacology, 2001, Volume: 41, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Desipramine; Dexmedetomidine; Electric Stimulation; Electrophysiology; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Male; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin

2001
Phenylephrine induces endogenous noradrenaline release in the rat vas deferens through nitric oxide synthase pathway.
    Pharmacology & toxicology, 2003, Volume: 93, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Desipramine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vas Deferens; Vasoconstrictor Agents

2003
Critical involvement of dopaminergic neurotransmission in impulsive decision making.
    Biological psychiatry, 2006, Jul-01, Volume: 60, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Choice Behavior; Clonidine; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Impulsive Behavior; Male; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Reward

2006
In vivo PET imaging of cardiac presynaptic sympathoneuronal mechanisms in the rat.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:7

    Topics: Animals; Carbon Radioisotopes; Desipramine; Ephedrine; Epinephrine; Male; Myocardium; Neurons; Phenylephrine; Radiopharmaceuticals; Rats; Rats, Wistar; Sympathetic Nervous System

2008
On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists.
    Psychopharmacology, 2012, Volume: 219, Issue:2

    Topics: Adrenergic Agonists; Animals; Attention; Choice Behavior; Clenbuterol; Clonidine; Desipramine; Dobutamine; Dose-Response Relationship, Drug; Inhibition, Psychological; Isoproterenol; Male; Methylphenidate; Phenylephrine; Rats; Rats, Wistar; Reaction Time; Serial Learning

2012
Removal of half the sympathetic innervation does not reduce vasoconstrictor responses in rat tail artery.
    The Journal of physiology, 2013, Jun-01, Volume: 591, Issue:11

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Desipramine; Idazoxan; Isometric Contraction; Muscle Denervation; Myocytes, Smooth Muscle; Neuromuscular Junction; Norepinephrine; Phenylephrine; Rats; Sympathetic Nervous System; Synaptic Potentials; Tail; Vasoconstriction

2013