desipramine has been researched along with phencyclidine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Lemaire, S; Rogers, C | 1 |
| Maurice, T; Vignon, J | 1 |
| Pumphrey, E; Seecof, R; Tarver, A; Tennant, FS | 1 |
| Giannini, AJ; Giannini, MC; Loiselle, RH | 1 |
| Giannini, AJ; Giannini, MC; Loiselle, RH; Malone, DA; Price, WA | 1 |
| Hursting, MJ; Opheim, KE; Raisys, VA | 1 |
| Leonard, BE; Tonge, SR | 1 |
| Aronstam, RS | 1 |
| McCann, M; Rawson, RA; Tennant, FS | 1 |
| Nabeshima, T; Noda, Y | 1 |
| Furukawa, H; Mamiya, T; Nabeshima, T; Noda, Y | 1 |
| Bönisch, H; Brüss, M; Hara, K; Izumi, F; Kawamura, M; Minami, K; Sata, T; Shigematsu, A; Toyohira, Y; Ueno, S; Yanagihara, N | 1 |
2 review(s) available for desipramine and phencyclidine
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
3 trial(s) available for desipramine and phencyclidine
| Article | Year |
|---|---|
Double-blind comparison of desipramine and placebo for treatment of phencyclidine or amphetamine dependence.
Topics: Amphetamines; Clinical Trials as Topic; Desipramine; Double-Blind Method; Humans; Phencyclidine; Placebos; Substance-Related Disorders | 1986 |
Space-based abstinence: alleviation of withdrawal symptoms in combinative cocaine-phencyclidine abuse.
Topics: Adult; Cocaine; Desipramine; Double-Blind Method; Humans; Male; Phencyclidine; Psychotherapy, Brief; Substance Withdrawal Syndrome | 1987 |
Treatment of depression in chronic cocaine and phencyclidine abuse with desipramine.
Topics: Adult; Clinical Trials as Topic; Cocaine; Depression; Desipramine; Humans; Male; Phencyclidine; Placebos; Substance Withdrawal Syndrome; Substance-Related Disorders | 1986 |
15 other study(ies) available for desipramine and phencyclidine
| Article | Year |
|---|---|
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship | 1989 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Characterization of [3H]desmethylimipramine binding in bovine adrenal medulla: interactions with sigma- and (or) phencyclidine-receptor ligands.
Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Desipramine; Dextromethorphan; Dizocilpine Maleate; Phenazocine; Phencyclidine; Piperidines; Potassium Chloride; Receptors, Opioid, delta; Receptors, Phencyclidine; Tranquilizing Agents | 1992 |
Desipramine and the phencyclidine derivative BTCP differently inhibit [3H]TCP binding to high- and low-affinity sites.
Topics: Animals; Binding, Competitive; Brain Stem; Cerebellum; Desipramine; Dopamine Agents; In Vitro Techniques; Kinetics; Male; Mice; Phencyclidine; Rats | 1991 |
Drug-specific Fab therapy in drug overdose.
Topics: Antidotes; Desipramine; Digoxin; Humans; Immunoglobulin Fab Fragments; Phencyclidine; Poisoning | 1987 |
Interaction of phencyclidine with drugs affecting noradrenaline metabolism in the rat brain.
Topics: Anesthetics; Animals; Brain; Brain Chemistry; Desipramine; Drug Antagonism; Drug Synergism; Norepinephrine; Normetanephrine; Phencyclidine; Piperidines; Rats; Tetrabenazine | 1972 |
Interactions of tricyclic antidepressants with a synaptic ion channel.
Topics: Acetylcholine; Amitriptyline; Amphibian Venoms; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Desipramine; Electric Organ; Fishes; Imipramine; Ion Channels; Nortriptyline; Phencyclidine; Receptors, Nicotinic | 1981 |
Withdrawal from chronic phencyclidine (PCP) dependence with desipramine.
Topics: Adolescent; Adult; Desipramine; Female; Humans; Male; Phencyclidine; Substance Withdrawal Syndrome; Substance-Related Disorders | 1981 |
[Behavioral assessment of neuroleptics (3)--Schizophrenia negative symptoms-like model induced by PCP].
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clozapine; Desipramine; Disease Models, Animal; Humans; Immobilization; Mice; Phencyclidine; Risperidone; Schizophrenia; Swimming | 1996 |
Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice.
Topics: Animals; Antidepressive Agents; Depression; Desipramine; Hallucinogens; Hydroxyindoleacetic Acid; Male; Mianserin; Mice; Phencyclidine; Prefrontal Cortex; Schizophrenia; Serotonin; Stress, Physiological; Swimming | 1997 |
Ketamine interacts with the noradrenaline transporter at a site partly overlapping the desipramine binding site.
Topics: Adrenal Medulla; Adrenergic Uptake Inhibitors; Analgesics; Anesthetics, Local; Animals; Binding Sites; Biological Transport; Cattle; Cell Membrane; Cells, Cultured; Cocaine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Hallucinogens; Ketamine; Norepinephrine; Phencyclidine | 1998 |