desipramine and orphenadrine

desipramine has been researched along with orphenadrine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Sen, S; Sinha, N1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ambrogi, F; Cassano, GB; Marazziti, D; Rotondo, A1
Chandra, O; Dhawan, KN; Gupta, GP; Saxena, RC1
Andersen, PR; Gibbs, P; Kubinski, H1
Hespe, W; van der Zee, P1
Bhargava, KP; Dixit, KS; Sinha, JN; Srimal, RC1
Garattini, S; Morselli, PL; Rizzo, M; Zaccala, M1
Balster, RL; Harvey, SA; Nicholson, KL; Wiley, JL1
TAIT, AC; TODRICK, A; YATES, CM1

Reviews

1 review(s) available for desipramine and orphenadrine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

13 other study(ies) available for desipramine and orphenadrine

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Analgesia by nefopam: does it act through serotonin?
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:5

    Topics: Analgesia; Blood Platelets; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Morphine; Nefopam; Orphenadrine; Serotonin Antagonists

1991
Assessment of anti-reserpine and anti-apomorphine activities of some psychic energizers in pigeons.
    Psychopharmacologia, 1969, Volume: 15, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Columbidae; Deanol; Desipramine; Female; Hydrazines; Imipramine; Male; Opipramol; Orphenadrine; Reserpine; Vomiting

1969
Effects of neuropharmacological agents on in vitro formation of complexes between nucleic acids and proteins.
    Neuropharmacology, 1974, Volume: 13, Issue:2

    Topics: Animals; Benztropine; Cattle; Chlorpromazine; Codeine; Desipramine; DNA, Bacterial; Escherichia coli; Histones; Lysergic Acid Diethylamide; Morphine; Neostigmine; Nucleic Acids; Orphenadrine; Phenytoin; Protein Binding; Proteins; RNA, Bacterial; RNA, Ribosomal; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Trihexyphenidyl

1974
Influence of orphenadrine HC1 and its N-demethylated derivatives on the in vitro uptake of noradrenaline and 5-hydroxytryptamine by rat brain slices.
    Neuropharmacology, 1973, Volume: 12, Issue:9

    Topics: Animals; Brain; Carbon Radioisotopes; Desipramine; Germ-Free Life; Imipramine; In Vitro Techniques; Kinetics; Male; Norepinephrine; Orphenadrine; Rats; Serotonin

1973
Central muscle relaxant activity of a dozen CNS active agents and a correlation with their psychotropic activity.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:1

    Topics: Amphetamine; Animals; Antidepressive Agents; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Desipramine; Dibenzothiazepines; Ephedrine; Female; Imipramine; Iproniazid; Male; Mephenesin; Monoamine Oxidase Inhibitors; Muscles; Orphenadrine; Phenelzine; Reflex; Thioridazine; Tranquilizing Agents

1968
Haloperidol-desipramine interaction in mice, rats and man.
    Chemico-biological interactions, 1970, Volume: 2, Issue:2

    Topics: Animals; Basal Ganglia Diseases; Benperidol; Butyrophenones; Chronic Disease; Desipramine; Drug Antagonism; Female; Haloperidol; Humans; Kinetics; Male; Mice; Middle Aged; Motor Activity; Muscles; Orphenadrine; Psychotic Disorders; Rats; Tremor

1970
Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats.
    Psychopharmacology, 2003, Volume: 165, Issue:4

    Topics: Acoustic Stimulation; Adrenergic Uptake Inhibitors; Alanine; Amantadine; Animals; Binding Sites; Desipramine; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ibogaine; Loudness Perception; Male; Memantine; Muscarinic Antagonists; Neural Inhibition; Orphenadrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Selective Serotonin Reuptake Inhibitors

2003
EFFECT OF IMIPRAMINE AND SOME ANALOGUES ON THE UPTAKE OF 5-HYDROXYTRYPTAMINE BY HUMAN BLOOD PLATELETS IN VITRO.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Amitriptyline; Antidepressive Agents; Blood Platelets; Chlorpromazine; Desipramine; Humans; Imipramine; In Vitro Techniques; Metabolism; Orphenadrine; Pharmacology; Research; Serotonin

1964