desipramine has been researched along with nortriptyline in 273 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 185 (67.77) | 18.7374 |
| 1990's | 37 (13.55) | 18.2507 |
| 2000's | 25 (9.16) | 29.6817 |
| 2010's | 20 (7.33) | 24.3611 |
| 2020's | 6 (2.20) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM | 1 |
| Chiang, GH; Unger, SH | 1 |
| Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD | 1 |
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Goetz, RM; Karpowich, NK; Law, CJ; Reith, ME; Wang, DN; Zhen, J; Zhou, Z | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Modestin, J; Petrin, A | 1 |
| Hollister, LE | 2 |
| Richelson, E | 1 |
| Lin, HL; Marks, MJ; Medzihradsky, F | 1 |
| Levine, RM; Maickel, RP; Spaulding, JH; Zabik, JE | 1 |
| Bickel, MH | 1 |
| Dorrity, F; Jobson, K; Linnoila, M | 1 |
| Biggs, JT; Petit, JM; Spiker, DG; Ziegler, VE | 1 |
| Adams, RF; Schmidt, GJ; Vandemark, FL | 1 |
| Davis, CM; Fenimore, DC; Meyer, CJ | 1 |
| Bailey, DN; Jatlow, PI; Langou, RA; Van Dyke, C | 1 |
| Lohmann, HJ; Miles, DG; Proelss, HF | 1 |
| Cooper, TB; Friedman, MJ; Green, R; Ives, JO; Nies, A; Ravaris, CL; Robinson, DS | 1 |
| Davis, CM; Fenimore, DC; Hsu, F; Meyer, CJ; Zlatkis, A | 1 |
| Breyer, U; Villumsen, K | 1 |
| Detaevernier, MR; Dryon, L; Massart, DL | 1 |
| Henry, BW; Overall, JE; Woodward, JA | 1 |
| Huang, CL; Liu, SJ; Waters, IW | 1 |
| Oksenkrug, GF | 1 |
| Maas, JW | 1 |
| Bobkiewicz, T; Chodera, A; Drutel, B; Szpunar, K | 1 |
| Bridges, JW; Dent, JG; Johnson, P | 1 |
| Barnes, JM; Barnes, NM; Champaneria, S; Costall, B; Hornsby, CD; Naylor, RJ | 1 |
| Field, SL; Murray, M | 1 |
| Borchardt, CM; Giesler, J; Reeve, E | 1 |
| Graf, U; van Schaik, N | 1 |
| Borsini, F; Lecci, A; Meli, A; Volterra, G | 1 |
| Bienenfeld, D; Burk, J; Geier, P; Kay, J; Marvel, NT; Nadolny, G; Slomowitz, M; Zimmer, L | 1 |
| Ayesh, R; Cholerton, S; Dawling, S; Hayler, A; Idle, JR; Oates, NS; Smith, RL; Widdop, B | 1 |
| Barrow, NE; Crismon, ML; Michals, M; Stanley, DA | 1 |
| Insel, TR; Winslow, JT | 1 |
| Ackerman, SH; Banay-Schwartz, M; Russ, MJ; Shindledecker, RD; Smith, GP | 1 |
| Badia, A; Sallés, J; Vila, E | 1 |
| Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H; Yasuda, N | 1 |
| Mizukami, Y; Yasuda, K | 1 |
| Fedoroff, JP; Morris, PL; Robinson, RG | 1 |
| von Ammon Cavanaugh, S | 1 |
| Perel, JM; Somogyi, GT | 1 |
| Small, GW | 1 |
| Eckert, ED; Hatsukami, D; Mitchell, JE; Pomeroy, C; Pyle, RL; Zimmerman, R | 1 |
| Richens, A; Tedstone, JE; Tsanaclis, LM; Williams, J; Wilson, JF | 1 |
| Coble, PA; Kupfer, DJ; Perel, JM; Pollock, B; Shipley, JA; Spiker, DG | 1 |
| Fernstrom, MH; Kupfer, DJ | 1 |
| Halliday, CA; Wise, H | 1 |
| Dorey, RC; Preskorn, SH; Widener, PK | 1 |
| Balon, R; Berchou, R; Ortiz, A; Pohl, R; Rainey, JM; Yeragani, VK | 1 |
| Bowden, CL; Brunswick, D; Carl, J; Frazer, A; Hanin, I; Kocsis, JH; Koslow, SH; Robins, E | 1 |
| Aberg-Wistedt, A; Bertilsson, L; Lidén, A; Otani, K; Spina, E | 1 |
| Collins, C; Hu, M; Izutsu, A; Jaklitsch, A; Pankey, S; Pirio, M; Singh, P | 1 |
| Bertilsson, L; Sjöqvist, F | 1 |
| Bredehoeft, SJ; Chaturvedi, AK; Hidding, JT; Rao, NG; Smith, JC | 1 |
| Adan, F; Allen, D; Coccaro, EF; Cooper, TB | 1 |
| Lydiard, RB | 1 |
| Borenstein, M; Brenner, R; Cooper, TB; Kane, JM; Lieberman, JA; Steinberg, H; Suckow, RF | 1 |
| Passananti, GT; Vessell, ES | 1 |
| Frisk-Holmberg, M; van der Kleijn, E | 1 |
| Orrenius, S; Schenkman, JB; von Bahr, C; Wilson, BJ | 1 |
| al-Sarraj, S; Beckett, AH | 1 |
| Tuomisto, J | 1 |
| Chinn, C; Weber, LJ | 1 |
| Coffer, AI; McDowall, RD; Robinson, AE | 1 |
| Loew, D; Taeschler, M | 1 |
| Zingales, I | 1 |
| Hawkins, DR; Mendels, J | 1 |
| Goldstein, FJ; Malseed, RT; Rossi, GV | 1 |
| Gaut, ZN | 2 |
| Mlejnkova, M; Rysánek, K; Spánkova, H; Synek, P | 1 |
| Cater, BR; Chapman, D; Hawes, SM; Saville, J | 1 |
| Carrara, C; Garattini, S; Jori, A; Paglialunga, S | 1 |
| Garattini, S; Jori, A; Paglialunga, S | 1 |
| Randrup, A; Scheel-Krüger, J | 1 |
| Otten, U; Zetler, G | 1 |
| Saarnivaara, L | 1 |
| Nybäck, H; Schubert, J; Sedvall, G | 1 |
| Chaplin, E; Eckhardt, SB; Hite, G; Maxwell, RE; Soares, JR | 1 |
| Sturman, G | 1 |
| Schrold, J | 2 |
| Lapin, IP; Oxenkrug, GF | 1 |
| Karobath, M | 1 |
| Bareggi, SR; Bonaccorsi, A; Franco, R; Garattini, S; Morselli, PL; Mundo, AS; Riva, E | 1 |
| Imai, S; Ogura, C; Okuma, T; Uchida, Y; Yogi, H | 1 |
| Benesová, O; Rysánek, K; Spánková, H | 1 |
| Christiansen, J; Gram, LF; Overo, KF | 1 |
| Gripenberg, J | 1 |
| Bonaccorsi, A; Garattini, S; Jori, A; Samanin, R | 1 |
| Berner, P; Kryspin-Exner, K; Poeldinger, W | 1 |
| Evans, DA | 1 |
| Fung, HL; Ow, YH | 1 |
| O'Malley, K; Sawyer, PR; Stevenson, IH | 1 |
| König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P | 1 |
| Orrenius, S; Schenkman, JB; von Bahr, C | 1 |
| Sjöqvist, F | 3 |
| Gaffney, T; Gard, H; Hanenson, I; Knapp, D; Walle, T | 1 |
| Connor, JD; Crawford, IL; Pardridge, WM | 1 |
| Boulu, R; Dupeyron, JP; Rossignol, P | 1 |
| Browning, M; O'Malley, K; Stevenson, I; Turnbull, MJ | 1 |
| Dandiya, PC; Kulkarni, SK | 1 |
| Mattila, MJ; Saarnivaara, L | 1 |
| Furlong, FW; Luby, ED | 1 |
| Hills, NF; Milner, G | 1 |
| Mitchell, PH; Stewart, JA | 1 |
| Haider, I | 1 |
| Deza, PC; Marjerrison, G; Silzer, JC | 1 |
| Borg, KO; Lagerström, PO; Westerlund, D | 1 |
| Rowland, M | 1 |
| Gajda, L; Grabowska, M; Maj, J | 1 |
| Maickel, RP; Sokol, GH | 1 |
| Attree, T; Sawyer, P; Turnbull, MJ | 1 |
| Webb, WL | 1 |
| Alexanderson, B; Bertilsson, L; Borgå, O; Sjöqvist, F | 1 |
| Orrenius, S; Sjöqvist, F; von Bahr, C | 1 |
| Oates, JA; Shand, DG | 1 |
| Appel, P; Eckel, K; Harrer, G | 1 |
| Bodi, T; Dykyj, R; Mapp, Y; Nodine, JH; Siegler, PE | 1 |
| Arieff, AJ | 1 |
| Azarnoff, DL; Borgå, O; Forshell, GP; Sjöqvist, F | 1 |
| Rohte, O | 3 |
| Renyi, AL; Ross, SB | 1 |
| Dodge, GA; Logue, MA; Schildkraut, JJ | 1 |
| Scanlon, FJ | 1 |
| Gross, R; Linker, H; Reuter, H | 1 |
| Greeff, K; Wagner, J | 2 |
| Opitz, K; Schniedermann, W | 1 |
| Eckhardt, SB; Hite, G; Maxwell, RA | 1 |
| Núnek, K | 1 |
| Ose, E | 1 |
| Alexanderson, B; Azarnoff, DL; Orrenius, S; Sjoqvist, F; von Bahr, C | 1 |
| Cosmides, GJ | 1 |
| Feighner, J; Robins, E; Schuckit, M | 1 |
| Avni, J; Edelstein, EL; Khazan, N; Sulman, FG | 1 |
| Corsico, N; Martelli, EA; Segre, AD; Tóth, E | 1 |
| Borchert, U; Opitz, K | 2 |
| Teien, A | 1 |
| Andrási, F; Borsy, J | 1 |
| Milner, G | 1 |
| Beattie, RR; Freeman, JW; Mundy, GR; Ryan, C | 1 |
| Levy, S | 1 |
| Dingell, JV; Sanders, E | 1 |
| Angst, J; Poeldinger, W | 1 |
| Schmitt, H | 1 |
| Hammer, W; Sjöqvist, F | 1 |
| Ropert, R; Sivadon, P | 1 |
| Schechter, MD | 1 |
| Beckett, AH; Hutt, AJ | 1 |
| Extein, I; Gold, MS; Pottash, AL | 1 |
| Crews, FT; Smith, CB | 2 |
| Aronstam, RS | 1 |
| Kirstein, L | 1 |
| Cutler, NR; Narang, PK | 1 |
| Cooke, RG; Persad, E; Reed, KL; Stancer, HC; Warsh, JJ | 1 |
| Audus, KL; Gordon, MA | 1 |
| Phillis, JW | 1 |
| Biegon, A | 1 |
| Orsulak, PJ; Sink, M; Weed, J | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Mattes, JA | 1 |
| Beierle, FA; Hubbard, RW | 1 |
| Stern, SL; Votolato, NA | 1 |
| Henauer, SA; Hollister, LE | 1 |
| Asnis, GM; Endicott, J; Halbreich, U; Nathan, RS; Novacenko, H; Ostrow, L; Sachar, EJ | 1 |
| Vinet, B | 1 |
| Briley, MS; Langer, SZ; Sette, M | 1 |
| Bagri, S; Fawcett, J; Javaid, JI; Sabelli, HC | 1 |
| Amsterdam, J; Brunswick, D; Mendels, J | 1 |
| Alexopoulos, GS; Shamoian, CA | 1 |
| Mendlewicz, J; Razavi, D | 1 |
| Lyskowksi, J; Nasrallah, HA; Schroeder, D | 1 |
| Keller, JM; Kwong, TC; Martinez, R | 1 |
| Friedel, RO | 1 |
| Ettigi, P; Friedel, RO; Joseph, A; Narasimhachari, N; Saady, JJ | 1 |
| Kabra, PM; Mar, NA; Marton, LJ | 1 |
| Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S | 1 |
| Brumback, RA; Staton, RD; Wilson, H | 1 |
| Bowers, LD; Breutzmann, DA | 1 |
| Reed, K | 1 |
| Bazán, E; Fuentes, JA; Galindo, A; Guillamón, A; Somoza, E; Valencia, A | 1 |
| Chinn, DM; Crouch, DJ; Jennison, TA; Peat, MA; Thatcher, GW | 1 |
| Jones, S; Turner, P | 1 |
| Alderton, HR | 1 |
| Canavan, D; Graff-Radford, SB; Gratt, BM | 1 |
| Biederman, J; Mick, E; Spencer, TJ; Wilens, TE | 1 |
| Dilsaver, SC; Swann, AC | 1 |
| Arndt, S; Perry, PJ; Zeilmann, C | 1 |
| Nelson, JC | 1 |
| Coutts, RT | 1 |
| el-Yazigi, A; Raines, DA | 1 |
| Wahba, WW; Winek, CL; Zaveri, NR | 1 |
| Biederman, J; Spencer, T; Steingard, R; Wilens, T | 1 |
| Roesler, TA; Wamboldt, MZ; Yancey, AG | 1 |
| Benazzi, F; Ciucci, G | 1 |
| Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A | 1 |
| Ahn, DK; Kim, YS; Park, JS | 1 |
| Ballesta, J; de la Torre, R; González, S; Ortuño, J; Pascual, JA | 1 |
| Koenig, JW; Mitchell, ME; Stickle, D; Turk, J; Way, BA | 1 |
| Holterman, K; Ohshima, T; Pounder, DJ; Takayasu, T | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Roos, P | 1 |
| Bohlin, K; Cotgreave, IA; Dahlin, KL; Ryrfeldt, A; Strindlund, J | 1 |
| Hatsuda, S; Hayashi, T; Kimura, H; Matsubara, M; Miura, K; Mori, T; Murakami, H; Ohara, M; Ohta, T; Sugita, S; Suzuki, S; Terashima, M | 1 |
| Bönisch, H; Bruss, M; Cox, PJ; Giros, B; Hamon, M; Roubert, C | 1 |
| Baba, J; Fujishiro, J; Imanishi, T; Kosaka, K | 1 |
| Hayashida, M; Jinno, K; Kawazoe, M; Saito, Y; Takeichi, T | 1 |
| WANG, RI | 1 |
| HORDERN, A | 1 |
| POLLITT, J | 1 |
| METYS, J; METYSOVA, J; VOTAVA, Z | 1 |
| METYS, J; METYSOVA, J | 1 |
| Murray, K; Murray, M | 1 |
| Amitai, Y; Frischer, H | 2 |
| Banaschewski, T; Heise, CA; Himpel, S; Rothenberger, A | 1 |
| Alexander, B; Kurpius, MP | 1 |
| Cantú, MD; Carrilho, E; Lacerda, CA; Lanças, FM; Queiroz, ME; Toso, DR | 1 |
| Costa, DT; de Castro E Silva, E; de Oliveira, IR; Fregoneze, JB; Quarantini, LC; Ribeiro, MG; Santana, RC | 1 |
| Alves, C; Fernandes, C; Lanças, FM; Rodrigues, JC; Santos-Neto, AJ | 1 |
| Nałecz-Jawecki, G | 1 |
| Duggan, C; Ferriter, M; Huband, N; Khalifa, N; Lieb, K; Stoffers, J; Völlm, BA | 1 |
| Barone, P | 1 |
| Fulda, S; Himmerich, H; Plümäkers, B; Rink, L; Sheldrick, AJ | 1 |
| Adar, T; Adler, SN; Bar-Gil Shitrit, A; Livovsky, DM; Lysy, J | 1 |
| Breaud, AR; Clarke, WA; Crutchfield, CA | 1 |
| Ingram, M; Lau, C; Martin, GM; Milway, JS; Morrison, G; Walling, SG | 1 |
| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
| Gowda, R; Kuzu, OF; Noory, MA; Robertson, GP | 1 |
| Aree, T | 1 |
| Cheung, NH; Gibbon, S; Khalifa, NR; McCarthy, L; Völlm, BA | 1 |
| Giles, R; Girard, MFC; Hopfgartner, G; Knight, P | 1 |
| Abelson, KSP; Kanui, TI; Makau, CM; Towett, PK | 1 |
| Yamini, Y; Zamani, R | 1 |
28 review(s) available for desipramine and nortriptyline
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine | 1976 |
Tricyclic antidepressants (first of two parts).
Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; Depression; Desipramine; Doxepin; Humans; Imipramine; Kinetics; Neurotransmitter Agents; Nortriptyline; Protriptyline | 1978 |
Poisoning by tricyclic antidepressant drugs: general and pharmacokinetic considerations.
Topics: Accidents, Home; Adolescent; Adult; Aged; Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain Chemistry; Child; Child, Preschool; Desipramine; Dibenzazepines; Drug Interactions; Female; Humans; Imipramine; Infant; Intestinal Absorption; Kinetics; Liver; Lung; Male; Mice; Middle Aged; Nortriptyline; Opipramol; Poisoning; Protein Binding; Rats; Suicide | 1975 |
Depression and cerebrovascular disease.
Topics: Cerebrovascular Disorders; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Male; Nortriptyline | 1990 |
Tricyclic antidepressants for medically ill geriatric patients.
Topics: Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Doxepin; Geriatrics; Humans; Nortriptyline | 1989 |
Slow hydroxylation of tricyclic antidepressants--relationship to polymorphic drug oxidation.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Debrisoquin; Desipramine; Female; Humans; Hydroxylation; Kinetics; Male; Middle Aged; Nortriptyline; Phenotype; Polymorphism, Genetic; Smoking; Twins, Dizygotic; Twins, Monozygotic | 1986 |
Tricyclic antidepressants--blood level measurements and clinical outcome: an APA Task Force report. Task Force on the Use of Laboratory Tests in Psychiatry.
Topics: Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Clinical Trials as Topic; Depressive Disorder; Desipramine; Hospitalization; Humans; Imipramine; Laboratories; Nortriptyline; Outcome and Process Assessment, Health Care; Research Design | 1985 |
Tricyclic-resistant depression: treatment resistance or inadequate treatment?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Humans; Imipramine; Intestinal Absorption; Kinetics; Nortriptyline; Patient Compliance | 1985 |
Utility of clinical chemical determinations of drug concentrations in biological fluids.
Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays | 1971 |
On the significance of drug-induced spectral changes in liver microsomes.
Topics: Alkaloids; Amphetamine; Aniline Compounds; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Hydroxylation; Microsomes, Liver; NADP; Nortriptyline; Oxidoreductases; Phenacetin; Rats; Spectrum Analysis; Testosterone; Tryptophan | 1972 |
[Monoamines and the pharmacological effects of tricyclic antidepressive agents].
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Central Nervous System; Chemical Phenomena; Chemistry; Desipramine; Humans; Hydroxyindoleacetic Acid; Imipramine; Methyltransferases; Monoamine Oxidase; Norepinephrine; Nortriptyline; Receptors, Drug; Serotonin | 1972 |
The ecology of drug therapy.
Topics: Adrenal Cortex Hormones; Biological Evolution; Desipramine; Ethnicity; Female; Genetic Variation; Genetics, Medical; Genotype; Glaucoma; Humans; Intraocular Pressure; Nortriptyline; Pharmaceutical Preparations; Pregnancy; Twins | 1974 |
Psychopharmacologic treatment of depression.
Topics: Affective Disorders, Psychotic; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Electroconvulsive Therapy; Humans; Kinetics; Lithium; Monoamine Oxidase Inhibitors; Nortriptyline; Triiodothyronine | 1984 |
Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.
Topics: Adipose Tissue; Adult; Aged; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Gastric Mucosa; Glomerular Filtration Rate; Humans; Imipramine; Kinetics; Middle Aged; Nordazepam; Nortriptyline | 1984 |
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Imipramine; Nortriptyline; Protriptyline | 1980 |
Tricyclic medication in children and the QT interval: case report and discussion.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; Contraindications; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Imipramine; Long QT Syndrome; Nortriptyline; Practice Guidelines as Topic | 1995 |
Tricyclic antidepressant concentrations in plasma: an estimate of their sensitivity and specificity as a predictor of response.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; ROC Curve; Sensitivity and Specificity | 1994 |
Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping.
Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug Interactions; Female; Humans; Hydroxylation; Imipramine; Isoenzymes; Male; Mephenytoin; Nortriptyline; Phenotype; Polymorphism, Genetic | 1994 |
Cardiovascular effects of tricyclic antidepressants in childhood asthma: a case series and review.
Topics: Adolescent; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Asthma; Blood Pressure; Bronchodilator Agents; Cardiovascular System; Child; Depressive Disorder; Desipramine; Electrocardiography; Female; Heart Rate; Humans; Imipramine; Male; Nortriptyline; Treatment Outcome | 1997 |
THE ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Depression; Depressive Disorder; Desipramine; Drug Therapy; Epidemiology; Humans; Imipramine; Mental Disorders; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Psychopharmacology | 1965 |
The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder.
Topics: Adrenergic alpha-Agonists; Adult; Antidepressive Agents, Tricyclic; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Guanfacine; Humans; Imipramine; Nortriptyline; Propylamines | 2005 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; Bromocriptine; Desipramine; Female; Humans; Male; Nortriptyline; Phenytoin; Psychotropic Drugs; Randomized Controlled Trials as Topic | 2010 |
Treatment of depressive symptoms in Parkinson's disease.
Topics: Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Depression; Desipramine; Dopamine Agonists; Humans; Levodopa; Nortriptyline; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline | 2011 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; Bromocriptine; Desipramine; Female; Humans; Male; Middle Aged; Nortriptyline; Phenytoin; Placebos; Psychotropic Drugs; Randomized Controlled Trials as Topic | 2020 |
15 trial(s) available for desipramine and nortriptyline
| Article | Year |
|---|---|
Plasma and erythrocyte levels of tricyclic antidepressants in depressed patients.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Biopharmaceutics; Clinical Trials as Topic; Depression; Desipramine; Doxepin; Erythrocytes; Humans; Imipramine; Middle Aged; Nortriptyline | 1978 |
Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects.
Topics: Adolescent; Adult; Amino Acids; Blood-Brain Barrier; Depressive Disorder; Desipramine; Double-Blind Method; Eating; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Tryptophan | 1990 |
Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa.
Topics: Adolescent; Adult; Antidepressive Agents; Bulimia; Clinical Trials as Topic; Desipramine; Feeding Behavior; Female; Fluoxetine; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nortriptyline; Random Allocation | 1989 |
Antidepressant-induced weight gain: a comparison study of four medications.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Nortriptyline; Weight Gain; Zimeldine | 1988 |
Sodium lactate infusions after treatment with tricyclic antidepressants: behavioral and physiological findings.
Topics: Antidepressive Agents, Tricyclic; Arousal; Clinical Trials as Topic; Desipramine; Double-Blind Method; Doxepin; Fear; Humans; Imipramine; Isoproterenol; Lactates; Lactic Acid; Nortriptyline; Panic; Psychological Tests | 1988 |
Tricyclic antidepressants--blood level measurements and clinical outcome: an APA Task Force report. Task Force on the Use of Laboratory Tests in Psychiatry.
Topics: Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Clinical Trials as Topic; Depressive Disorder; Desipramine; Hospitalization; Humans; Imipramine; Laboratories; Nortriptyline; Outcome and Process Assessment, Health Care; Research Design | 1985 |
Therapy possibilities for therapy-resistant depressions.
Topics: Amitriptyline; Antidepressive Agents; Chronic Disease; Clinical Trials as Topic; Depression; Desipramine; Drug Resistance; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Imipramine; Nortriptyline; Remission, Spontaneous; Time Factors; Tranquilizing Agents | 1974 |
Lithium in the control of mania.
Topics: Adult; Amitriptyline; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Nortriptyline; Thioridazine; Tranylcypromine; Trifluoperazine | 1967 |
A double-blind assessment of antidepressants in the treatment of 212 enuretic patients.
Topics: Clinical Trials as Topic; Desipramine; Enuresis; Epilepsy; Female; Humans; Humidity; Imipramine; Male; Mental Disorders; Nortriptyline; Sex Factors; Temperature | 1968 |
A comparative trial of desipramine and nortriptyline in depression.
Topics: Adolescent; Adult; Aged; Anxiety; Clinical Trials as Topic; Depression; Desipramine; Electroconvulsive Therapy; Female; Humans; Middle Aged; Nortriptyline; Placebos; Sleep Initiation and Maintenance Disorders | 1968 |
A comparative investigation of desipramine and nortriptyline in the treatment of depression.
Topics: Adult; Aged; Anxiety; Clinical Trials as Topic; Depression; Desipramine; Female; Humans; Male; Middle Aged; Nortriptyline; Time Factors | 1968 |
Verbal behaviour changes with depression treatment.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents; Clinical Trials as Topic; Depression; Desipramine; Female; Humans; Imipramine; Interpersonal Relations; Interview, Psychological; Male; Middle Aged; Nortriptyline; Placebos; Psychiatric Status Rating Scales; Self Concept; Verbal Behavior | 1969 |
A pharmacokinetic approach to the treatment of depression.
Topics: Barbiturates; Biotransformation; Blood Pressure; Chromatography, Gas; Clinical Trials as Topic; Dealkylation; Depression; Desipramine; Diseases in Twins; Humans; Iris; Kinetics; Mass Spectrometry; Norepinephrine; Nortriptyline; Placebos; Time Factors; Tyramine | 1971 |
A variable dose phase 3, human bioassay of nortriptyline.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1965 |
Desipramine and nortriptyline in mental depression.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Desipramine; Humans; Nortriptyline | 1966 |
231 other study(ies) available for desipramine and nortriptyline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Desipramine; gamma-Aminobutyric Acid; Male; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Triazoles | 1988 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes | 1999 |
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.
Topics: Amino Acid Sequence; Animals; Antidepressive Agents, Tricyclic; Bacterial Proteins; Binding Sites; Caenorhabditis elegans Proteins; Cell Line; Conserved Sequence; Crystallography, X-Ray; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Drosophila Proteins; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Plasma Membrane Neurotransmitter Transport Proteins; Protein Binding; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Sequence Homology, Amino Acid; Serotonin | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Tricyclic antidepressants and histamine H1 receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic | 1979 |
Drug inhibitable ecta-ATPase in leukocytes.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cations, Divalent; Cations, Monovalent; Desipramine; Dinitrophenols; Enzyme Inhibitors; Kinetics; Leukocytes; Male; Nortriptyline; Oligomycins; Ouabain; Potassium; Rats; Sodium; Sulfhydryl Reagents; Thioridazine; Trifluoperazine | 1975 |
Interactions of tricyclic antidepressant drugs with deprivation-induced fluid consumption by rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Drinking Behavior; Fenclonine; Imipramine; Male; Methyltyrosines; Nortriptyline; Protriptyline; Rats; Water Deprivation | 1977 |
Tricyclic antidepressant overdose: incidence of symptoms.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Electrocardiography; Heart; Humans; Imipramine; Nortriptyline | 1977 |
Liquid-chromatographic procedure for tricyclic drugs and their metabolites in plasma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Humans; Imipramine; Nortriptyline | 1978 |
Determination of drugs in plasma by high-performance thin-layer chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1978 |
Tricyclic antidepressants: plasma levels and clinical findings in overdose.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Electrocardiography; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1978 |
High-performance liquid-chromatographic simultaneous determination of commonly used tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline | 1978 |
Relationship between age and tricyclic antidepressant plasma levels.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Body Weight; Depression; Desipramine; Female; Half-Life; Heart; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1977 |
High-performance thin-layer chromatographic determination of psychopharmacologic agents in blood serum.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1977 |
Measurement of plasma levels of tricylic psychoactive drugs and their metabolites by UV reflectance photometry of thin layer chromatograms.
Topics: Amitriptyline; Chromatography, Thin Layer; Clozapine; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Perazine; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1976 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1975 |
Interactions of tricyclic antidepressants and barbiturates in barbiturate-tolerant and nontolerant rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Barbiturates; Brain Chemistry; Desipramine; Drug Interactions; Drug Tolerance; Imipramine; Male; Microsomes, Liver; Nortriptyline; Pentobarbital; Rats; Sleep; Time Factors | 1975 |
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines | 1975 |
Biogenic amines and depression. Biochemical and pharmacological separation of two types of depression.
Topics: Amitriptyline; Biogenic Amines; Depression; Desipramine; Dextroamphetamine; Humans; Hydroxyindoleacetic Acid; Imipramine; Metanephrine; Methoxyhydroxyphenylglycol; Normetanephrine; Nortriptyline; Vanilmandelic Acid | 1975 |
[Postsynaptic attack of tricyclic antidepressive agents in the circulatory system].
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Dose-Response Relationship, Drug; Female; Heart; Hemodynamics; Imipramine; Male; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Rats; Receptors, Drug | 1975 |
The effects of some pharmacologically active amines on the rate of gastric emptying in rats.
Topics: Animals; Depression, Chemical; Desipramine; Dextroamphetamine; Imipramine; Male; Nortriptyline; Parasympatholytics; Rats; Rats, Inbred Strains; Stomach; Structure-Activity Relationship | 1976 |
Depression in elderly is common but undertreated, says expert panel.
Topics: Age Factors; Aged; Antidepressive Agents; Depression; Desipramine; Humans; Nortriptyline | 1992 |
Pharmacological comparison of the rat and guinea-pig cortical high affinity 5-hydroxytryptamine uptake system.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Citalopram; Desipramine; Female; Guinea Pigs; Kinetics; Nortriptyline; Rats; Serotonin; Synaptosomes | 1992 |
Inhibition and metabolite complexation of rat hepatic microsomal cytochrome P450 by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desipramine; Hydroxylation; Imipramine; Male; Microsomes, Liver; Nortriptyline; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Testosterone | 1992 |
Low dose tricyclic tachycardia.
Topics: Adolescent; Depressive Disorder; Desipramine; Electrocardiography, Ambulatory; Female; Humans; Nortriptyline; Tachycardia | 1991 |
Genotoxicity evaluation of five tricyclic antidepressants in the wing somatic mutation and recombination test in Drosophila melanogaster.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; DNA; Dose-Response Relationship, Drug; Drosophila melanogaster; Imipramine; Mutagenicity Tests; Nortriptyline; Protriptyline; Recombination, Genetic | 1991 |
Desipramine and nortriptyline antagonize apomorphine and reserpine hypothermia by a different mechanism.
Topics: Animals; Apomorphine; Body Temperature; Desipramine; Haloperidol; Hypothermia; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Nortriptyline; Reserpine | 1990 |
Use of tricyclic antidepressants in recipients of heart transplants.
Topics: Adaptation, Psychological; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Heart Transplantation; Humans; Middle Aged; Nortriptyline; Postoperative Complications | 1991 |
Comparative effects of the diastereoisomers, quinine and quinidine in producing phenocopy debrisoquine poor metabolisers (PMs) in healthy volunteers.
Topics: Adult; Debrisoquin; Desipramine; Female; Humans; Male; Metabolic Clearance Rate; Molecular Structure; Nortriptyline; Phenotype; Quinidine; Quinine; Reference Values; Stereoisomerism | 1991 |
Elevated tricyclic antidepressant plasma concentrations associated with fluoxetine: two case reports.
Topics: Adult; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Metabolic Clearance Rate; Nortriptyline | 1990 |
Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups.
Topics: Animals; Body Temperature; Catecholamines; Citalopram; Clomipramine; Desipramine; Flumazenil; Mazindol; Motor Activity; Naltrexone; Nortriptyline; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stress, Psychological; Ultrasonics; Vocalization, Animal | 1990 |
Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle.
Topics: Animals; Antidepressive Agents; Cocaine; Desipramine; Electric Stimulation; Male; Mianserin; Muscle Contraction; Muscles; Nomifensine; Normetanephrine; Nortriptyline; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine | 1990 |
Characterization of an internal-surface reversed-phase silica support for liquid chromatography and its application to assays of drugs in serum.
Topics: Aspirin; Blood Chemical Analysis; Chromatography, Liquid; Desipramine; Humans; Injections; Nortriptyline; Pharmaceutical Preparations; Salicylates; Silicon Dioxide | 1990 |
[Therapeutic drug monitoring of tricyclic antidepressants].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biological Availability; Chromatography, Gas; Chromatography, High Pressure Liquid; Desipramine; Humans; Immunoenzyme Techniques; Nortriptyline | 1990 |
Drug-drug interactions of fluoxetine with tricyclics.
Topics: Depressive Disorder; Desipramine; Drug Synergism; Drug Therapy, Combination; Fluoxetine; Humans; Metabolic Clearance Rate; Nortriptyline | 1990 |
Antagonism by tricyclic antidepressants of the muscarinic receptors located on the adrenergic nerve endings in rabbit heart atrium.
Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Desipramine; Electric Stimulation; Heart; Imipramine; Male; Norepinephrine; Nortriptyline; Oxotremorine; Parasympatholytics; Rabbits; Receptors, Muscarinic; Sympathetic Nervous System | 1989 |
External quality assurance of tricyclic antidepressant measurements in serum: eight years of progress?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Nortriptyline; Quality Control | 1989 |
Antidepressants and EEG sleep: search for specificity.
Topics: Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Humans; Nortriptyline; Sleep; Sleep Stages; Zimeldine | 1987 |
Why is amitriptyline much weaker than desipramine at decreasing beta-adrenoceptor numbers?
Topics: Amitriptyline; Animals; Desipramine; In Vitro Techniques; Male; Norepinephrine; Nortriptyline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Results compared for tricyclic antidepressants as assayed by liquid chromatography and enzyme immunoassay.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Immunoenzyme Techniques; Nortriptyline | 1988 |
Cerebrospinal fluid levels of amitriptyline, nortriptyline, imipramine and desmethylimipramine. Relationship to plasma levels and treatment outcome.
Topics: Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Female; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Male; Nortriptyline; Psychiatric Status Rating Scales | 1985 |
Alprazolam does not inhibit the metabolism of nortriptyline in depressed patients or inhibit the metabolism of desipramine in human liver microsomes.
Topics: Adult; Alprazolam; Depressive Disorder; Desipramine; Drug Interactions; Female; Humans; Hydroxylation; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Nortriptyline | 1988 |
Quantitative homogeneous enzyme immunoassays for amitriptyline, nortriptyline, imipramine, and desipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Cross Reactions; Desipramine; Humans; Imipramine; Immunoenzyme Techniques; Methods; Nortriptyline | 1986 |
Two tricyclic antidepressant poisonings: levels of amitriptyline, nortriptyline and desipramine in post-mortem biological samples.
Topics: Adult; Amitriptyline; Chromatography, High Pressure Liquid; Desipramine; Humans; Male; Nortriptyline; Suicide; Verapamil | 1987 |
Plasma-serum differences in the assessment of tricyclic antidepressant blood levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Nortriptyline; Plasma | 1987 |
Tricyclic antidepressant and metabolite levels in chronic renal failure.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chromatography, Liquid; Depression; Desipramine; Female; Half-Life; Humans; Imipramine; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Nortriptyline; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis | 1985 |
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1972 |
Metabolism of amitriptyline, nortriptyline, imipramine and desipramine to yield hydroxylamines.
Topics: Amitriptyline; Animals; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Guinea Pigs; Hydroxylamines; Imipramine; In Vitro Techniques; Mass Spectrometry; Microsomes, Liver; Mitochondria, Liver; Nortriptyline; Rabbits | 1973 |
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine | 1974 |
The actions of several psychoactive agents upon the muscarinic mechanisms in the superior cervical ganglion of the cat.
Topics: Alkynes; Animals; Atropine; Carbamates; Cats; Desipramine; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Ganglia, Autonomic; Ganglia, Spinal; Heart Rate; Hexamethonium Compounds; Hydrazines; Injections, Intra-Arterial; Male; Methylphenidate; Muscle Contraction; Nictitating Membrane; Nortriptyline; Parasympathetic Nervous System; Parasympathomimetics; Pargyline; Piperidines; Quaternary Ammonium Compounds | 1974 |
Toxicology of some autopsy cases involving tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents; Autopsy; Brain Chemistry; Desipramine; Dibenzazepines; Ethanol; Female; Humans; Imipramine; Kidney; Liver; Lung; Male; Middle Aged; Nortriptyline; Protein Binding; Spleen; Stomach | 1974 |
[The effect of tricyclic antidepressants on rabbit 5-hydroxytryptophan hyperthermia].
Topics: Animals; Antidepressive Agents; Desipramine; Fever; Imipramine; Nortriptyline; Rabbits; Serotonin; Tryptophan | 1966 |
Systematic identification of psychotropic drugs by thin layer chromatography. II.
Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Humans; Imipramine; Male; Meprobamate; Nortriptyline; Phenothiazines; Schizophrenia; Silicon Dioxide; Thioridazine; Tranquilizing Agents | 1968 |
Sleep and depression. IV. Longitudinal studies.
Topics: Adult; Depression; Desipramine; Electroconvulsive Therapy; Ethynodiol Diacetate; Female; Hospitalization; Humans; Male; Meprobamate; Mestranol; Middle Aged; Nortriptyline; Sleep; Sleep Wake Disorders; Sleep, REM; Wakefulness | 1971 |
Potentiation of monoaminergic activity in peripheral ganglia by tricyclic antidepressants.
Topics: Action Potentials; Animals; Antidepressive Agents; Cats; Desipramine; Dibenzocycloheptenes; Dopamine; Drug Synergism; Epinephrine; Ganglia; Norepinephrine; Nortriptyline; Propranolol; Serotonin; Synaptic Transmission; Time Factors | 1972 |
Influence of various substances which induce and inhibit aggregation on the uptake of deoxyglucose by human blood platelets.
Topics: Adenosine Diphosphate; Amitriptyline; Antidepressive Agents; Blood Glucose; Blood Platelets; Bucladesine; Carbon Radioisotopes; Chlorpromazine; Cyproheptadine; Desipramine; Epinephrine; Glucose; Humans; In Vitro Techniques; Norepinephrine; Nortriptyline; Platelet Adhesiveness; Promethazine; Serotonin; Thrombin | 1974 |
Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.
Topics: 1-Propanol; Adenosine Diphosphate; Adenosine Monophosphate; Aminophylline; Blood Platelets; Caffeine; Chlorpromazine; Cyclic AMP; Desipramine; Dibenzothiepins; Epinephrine; Imipramine; Nortriptyline; Phosphoric Diester Hydrolases; Piperazines; Platelet Adhesiveness | 1974 |
Lipid phase transitions and drug interactions.
Topics: Amitriptyline; Binding Sites; Calorimetry; Desipramine; Electron Spin Resonance Spectroscopy; Imipramine; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Morphinans; Morphine; Nortriptyline; Palmitic Acids; Phosphatidylcholines; Structure-Activity Relationship; Temperature; Thermodynamics | 1974 |
Pharmacological studies on modaline sulphate (w 3207).
Topics: Antidepressive Agents; Desipramine; Dibenzylchlorethamine; Dihydroxyphenylalanine; Fever; Hydrazines; Isoproterenol; Monoamine Oxidase Inhibitors; Nortriptyline; Phentolamine; Proadifen; Propranolol; Reserpine; Sympatholytics; Tryptamines | 1965 |
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine | 1967 |
Evidence for a cholinergic mechanism in brain involved in the tetrabenazine reversal by thymoleptic drugs.
Topics: Animals; Antidepressive Agents; Brain; Desipramine; Imipramine; Male; Motor Activity; Nortriptyline; Parasympathetic Nervous System; Rats; Reserpine; Tetrabenazine | 1969 |
[Aggressiveness of the rat following combined treatment with monomaime oxidase inhibitors and other psychotropic drugs, especially thymoleptics].
Topics: Aggression; Alkaloids; Amitriptyline; Amphetamine; Animals; Anthracenes; Body Temperature; Central Nervous System; Desipramine; Dibenzazepines; Dihydroxyphenylalanine; Humans; Hydrazines; Imipramine; Indoles; Iproniazid; Isocarboxazid; Male; Nortriptyline; Opipramol; Pargyline; Phenelzine; Rats; Stimulation, Chemical; Tranylcypromine | 1969 |
Analgesic activity of some sympathetic drugs and their effect on morphine analgesia in rabbits.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analgesia; Animals; Brain; Cocaine; Desipramine; Dopamine; Drug Synergism; Electric Stimulation; Epinephrine; Guanethidine; Isoproterenol; Male; Methoxamine; Methyltyrosines; Morphine; Norepinephrine; Nortriptyline; Pain; Phenoxybenzamine; Rabbits; Sympathomimetics | 1969 |
Effect of antidepressant drugs on accumulation and disappearance of monoamines formed in vivo from labelled precursors in mouse brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Carbon Isotopes; Desipramine; Dopamine; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Serotonin; Tritium; Tryptophan; Tyrosine | 1970 |
Conformational similarities between molecular models of phenethylamine and of potent inhibitors of the uptake of tritiated norepinephrine by adrenergic nerves in rabbit aorta.
Topics: Animals; Antidepressive Agents; Aorta; Chemical Phenomena; Chemistry; Cocaine; Desipramine; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methylphenidate; Models, Structural; Norepinephrine; Nortriptyline; Phenethylamines; Piperidines; Rabbits; Sensory Receptor Cells; Sympathetic Nervous System; Tritium; Tyramine | 1970 |
Modification by a tricyclic series of compounds of the noradrenaline effect on the cat nictitating membrane.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Desipramine; Dibenzazepines; Drug Synergism; Imipramine; Nictitating Membrane; Norepinephrine; Nortriptyline | 1971 |
Behavioural effects od d-amphetamine alone and in combination with antidepressants, antihistamines or other psychotropic drugs in young chicks.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Chickens; Chlorpheniramine; Cocaine; Desipramine; Dextroamphetamine; Diphenhydramine; Drug Antagonism; Drug Interactions; Histamine H1 Antagonists; Imipramine; Male; Nortriptyline; Promethazine | 1972 |
Effect of dimethyl and monomethyl tricyclic antidepressants on central 5-hydroxytryptamine processes in the frog.
Topics: Amitriptyline; Animals; Antidepressive Agents; Anura; Brain; Desipramine; Dibenzazepines; Imipramine; Male; Muscle Contraction; Nortriptyline; Rana temporaria; Serotonin | 1971 |
[Tricyclic anti-depressant drugs and dopamine sensitive adenylcyclase from rat caudate nuclei].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amitriptyline; Animals; Antidepressive Agents; Basal Metabolism; Caudate Nucleus; Chlorpromazine; Desipramine; Dopamine; Imipramine; Nortriptyline; Rats; Stimulation, Chemical | 1974 |
Relationships between tricyclic antidepressant concentrations, 1-3H-noradrenaline uptake and chronotropic effect in isolated rat atria.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Radioisotopes; Chromatography, Thin Layer; Clomipramine; Dealkylation; Desipramine; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Female; Heart Atria; Heart Rate; Norepinephrine; Nortriptyline; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors; Tritium | 1974 |
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood Pressure; Depression; Desipramine; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Motor Activity; Nortriptyline; Pulse; Time Factors; Triiodothyronine; Verbal Behavior | 1974 |
Comparison of the effects of tetracyclic and tricyclic antidepressants on the serotonin uptake by human thrombocytes in vitro.
Topics: Antidepressive Agents; Blood Platelets; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin | 1974 |
Pharmacokinetic interaction between neuroleptics and tricyclic antidepressants in the rat.
Topics: Animals; Brain; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Feces; Glucuronates; Heart; Imipramine; Injections, Intraperitoneal; Male; Nortriptyline; Perphenazine; Rats | 1974 |
Incorporation of imipramine into isolated rat peritoneal mast cells in vitro.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Binding Sites; Calcium; Cell Membrane Permeability; Chlorpromazine; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Female; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Leukocytes; Male; Mast Cells; Nortriptyline; Rats; Receptors, Drug; Reserpine; Serotonin; Temperature | 1974 |
Functional group contribution in ion-pair extraction of tricyclic amines.
Topics: Amitriptyline; Bromides; Chemical Phenomena; Chemistry; Chlorates; Chlorides; Desipramine; Imipramine; Iodides; Ions; Mathematics; Naphthalenes; Nitrates; Nortriptyline; Spectrophotometry, Ultraviolet; Tosyl Compounds | 1972 |
Proceedings: Effect of tricyclic antidepressants on drug metabolism.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Hexobarbital; Humans; Imipramine; Liver; Male; Nortriptyline; Rats | 1972 |
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin.
Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents | 1972 |
Effect of phenobarbital and 3,4-benzpyrene treatment of rats on the microsomal binding and hydroxylation of nortriptyline and desmethyl-imipramine: evidence for qualitative changes in cytochrome P-450-ligand interaction following phenobarbital pretreatmen
Topics: Animals; Benzopyrenes; Binding Sites; Chromatography, Gas; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Ligands; Male; Microsomes, Liver; Mixed Function Oxygenases; Nortriptyline; Phenobarbital; Protein Binding; Rats; Receptors, Drug; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1972 |
[Differences between individuals in human pharmacokinetics. Clinical significance].
Topics: Binding Sites; Desipramine; Epilepsy; Female; Humans; Male; Nortriptyline; Pharmacogenetics; Phenytoin | 1972 |
Binding of cyproheptadine-(N-methyl- 14 C) by human blood platelets: inhibition by phenothiazines and tricyclic antidepressants.
Topics: Amitriptyline; Blood Platelets; Carbon Isotopes; Centrifugation; Chlorpromazine; Cyproheptadine; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phenothiazines; Platelet Adhesiveness; Promethazine | 1973 |
Studies on the disposition of amitriptyline and other tricyclic antidepressant drugs in man as it relates to the management of the overdosed patient.
Topics: Adult; Amitriptyline; Antidepressive Agents; Charcoal; Chromatography, Gas; Desipramine; Female; Gastric Juice; Humans; Imipramine; Male; Mass Spectrometry; Nortriptyline; Poisoning | 1973 |
Permeability changes in the blood-brain barrier induced by nortriptyline and chlorpromazine.
Topics: Amitriptyline; Animals; Autoradiography; Blood-Brain Barrier; Brain; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Cerebral Cortex; Chlorpromazine; Desipramine; Diphenhydramine; Dopamine; Imipramine; In Vitro Techniques; Inulin; Male; Mannitol; Molecular Weight; Nortriptyline; Rats; Tritium | 1973 |
[Evaluation of central antireserpine effect by the use of light blink reflex (author's transl)].
Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Diethylamines; Dimethylamines; Ethylenediamines; Glycolates; Imipramine; Light; Nortriptyline; Propylamines; Rabbits; Reflex; Reserpine | 1973 |
Stimulation of drug metabolism in man by tricyclic antidepressants.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Amitriptyline; Amobarbital; Analysis of Variance; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Humans; Hydrocortisone; Hydroxycorticosteroids; Imipramine; Male; Nortriptyline; Stimulation, Chemical; Time Factors | 1973 |
Effects of antidepressant agents on open field behaviour in rats.
Topics: Animals; Behavior, Animal; Desipramine; Humans; Imipramine; Male; Nortriptyline; Pargyline; Rats; Stereotyped Behavior; Time Factors; Tranylcypromine | 1973 |
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors | 1974 |
Fluorimetric determinations by ion pair extraction. 3. Extraction constants of ion pairs between anthracene-2-sulphonate and mono- and divalent amines.
Topics: Amines; Amitriptyline; Anthracenes; Desipramine; Dibenzazepines; Emetine; Hydrocarbons, Halogenated; Imipramine; Ions; Nortriptyline; Prenylamine; Spectrometry, Fluorescence; Sulfonic Acids | 1972 |
Application of clearance concepts to some literature data on drug metabolism in the isolated perfused liver preparation and in vivo.
Topics: Analgesics; Animals; Antidepressive Agents; Antipyrine; Desipramine; Half-Life; In Vitro Techniques; Ketones; Kinetics; Liver; Models, Biological; Nortriptyline; Perfusion; Phenylbutazone; Rats; Tremorine | 1972 |
Effect of apomorphine on motility in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benzoates; Benzyl Compounds; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Esters; Fluorine; Haloperidol; Hydrazines; Male; Motor Activity; Nialamide; Nortriptyline; Phenoxybenzamine; Rats; Rats, Inbred Strains; Reserpine; Serine; Spiro Compounds; Stimulation, Chemical; Thiocarbamates; Tranquilizing Agents; Tyrosine | 1972 |
Toxic interactions of d-amphetamine and tricyclic antidepressants in mice.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Antagonism; Drug Interactions; Drug Synergism; Imipramine; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nortriptyline; Promazine; Time Factors | 1972 |
Interaction between digoxin and tricyclic antidepressants in the rat.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Heart; Heart Arrest; Imipramine; Male; Nortriptyline; Rats; Reserpine; Stress, Physiological | 1972 |
The use of psychopharmacological drugs in the aged.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Anxiety; Barbiturates; Butyrophenones; Dementia; Desipramine; Dextroamphetamine; Diazepam; Humans; Imipramine; Isocarboxazid; Mental Disorders; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Phenothiazines; Phytotherapy; Piperazines; Plants, Medicinal; Rauwolfia; Thiothixene; Tranquilizing Agents; Tranylcypromine; Xanthenes | 1971 |
Studies on the metabolism and pharamcokinetics of nortriptyline and desmethylimipramine in man.
Topics: Chromatography, Gas; Desipramine; Humans; Kinetics; Mass Spectrometry; Nortriptyline | 1971 |
Interaction of imipramine, desmethylimipramine, nortriptyline and 1-naphthol with microsomal preparations.
Topics: Animals; Desipramine; Drug Interactions; Hydroxylation; Imipramine; Microsomes, Liver; Naphthalenes; Naphthols; Nortriptyline; Rats | 1971 |
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine | 1971 |
[Changes in tonus of the bladder and its sphincter under thymoleptic treatment. Cystomanometric measurements in man].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Carbachol; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Manometry; Middle Aged; Muscle Tonus; Nortriptyline; Pressure; Urinary Bladder; Water-Electrolyte Balance | 1971 |
Plasma protein binding of tricyclic anti-depressants in man.
Topics: Amitriptyline; Antidepressive Agents; Blood Proteins; Carbon Isotopes; Desipramine; Humans; Imipramine; Nortriptyline; Phenytoin; Protein Binding; Temperature; Tritium | 1969 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology | 1969 |
Inhibition of the uptake of tritiated 5-hydroxytryptamine in brain tissue.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antimetabolites; Brain; Cocaine; Desipramine; Imipramine; In Vitro Techniques; Mice; Nortriptyline; Reserpine; Serotonin; Tritium; Tryptamines | 1969 |
Effects of tricyclic antidepressants on the uptake and mabolism of intracisternally administered norepinephrine-H3 in rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Brain Chemistry; Cell Membrane; Cerebral Ventricles; Desipramine; Imipramine; Injections; Injections, Intraperitoneal; Male; Mitochondria; Norepinephrine; Normetanephrine; Nortriptyline; Rats; Tritium | 1969 |
Use of antidepressant drugs during the first trimester.
Topics: Amitriptyline; Desipramine; Embryo, Mammalian; Female; Gestational Age; Humans; Imipramine; Nortriptyline; Pregnancy | 1969 |
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds].
Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine | 1969 |
[Cardiodepressive and local anesthetic effect of thymoleptics. Comparative studies with imipramine, desipramine, amitriptyline, nortriptyline and melitracene].
Topics: Amitriptyline; Anesthetics, Local; Animals; Anthracenes; Cornea; Depression, Chemical; Desipramine; Drug Synergism; Guinea Pigs; Heart Rate; Imipramine; In Vitro Techniques; Norepinephrine; Nortriptyline; Rabbits; Time Factors; Tyramine | 1969 |
[Thymoleptics and lipolysis].
Topics: Adipose Tissue; Amitriptyline; Animals; Antidepressive Agents; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Fatty Acids, Nonesterified; Imipramine; In Vitro Techniques; Lipid Metabolism; Male; Norepinephrine; Nortriptyline; Photometry; Rats; Stimulation, Chemical; Tranquilizing Agents | 1969 |
Kinetic and thermodynamic considerations regarding the inhibition by tricyclic antidepressants of the uptake of tritiated norepinephrine by the adrenergic nerves in rabbit aortic strips.
Topics: Animals; Antidepressive Agents; Aorta; Desipramine; Energy Transfer; Female; Imipramine; Kinetics; Male; Muscle Contraction; Muscles; Neurons; Norepinephrine; Nortriptyline; Protein Binding; Rabbits; Sympathetic Nervous System; Tritium; Tyramine | 1970 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine | 1970 |
[Clinical antidepressant drug therapy].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Nortriptyline; Prognosis | 1970 |
A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats.
Topics: Animals; Antipyrine; Desipramine; Enzyme Induction; In Vitro Techniques; Liver; Male; Nortriptyline; Perfusion; Phenobarbital; Phenylbutazone; Rats; Tremorine | 1970 |
[Clinical pharmacology: clinical pharmacokinetics in patient care].
Topics: Desipramine; Humans; Kinetics; Nortriptyline; Pharmaceutical Preparations | 1970 |
Aggressive behaviour in chicks induced by tricyclic antidepressants.
Topics: Aggression; Animals; Behavior, Animal; Chickens; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Female; Humans; Imipramine; Male; Motor Activity; Nortriptyline | 1970 |
Pharmacology-toxicology.
Topics: Antidepressive Agents; Blood Pressure; Brain; Contraceptives, Oral; Cytochromes; Desipramine; Diazepam; Endoplasmic Reticulum; Histamine; Lidocaine; Liver; Methylphenidate; Methyltyrosines; National Institutes of Health (U.S.); Norepinephrine; Norethindrone; Nortriptyline; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Placenta; Progesterone; Smoking; United States | 1970 |
Antianxiety and anti-depressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Depression; Desipramine; Dibenzoxepins; Humans; Imipramine; Nortriptyline; Tranquilizing Agents | 1970 |
Observation of the grooming behaviour of reserpinized white mice as a method for investigating reserpine antagonism and synergism.
Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Charcoal; Desipramine; Dextroamphetamine; Dibenzazepines; Drug Synergism; Female; Grooming; Imipramine; Injections, Intravenous; Iproniazid; Methods; Mice; Nortriptyline; Propylamines; Reserpine | 1970 |
[Animal experiments to study the cardiotoxic effect of thymoleptics].
Topics: Amitriptyline; Animals; Blood Pressure; Cats; Desipramine; Drug Synergism; Epinephrine; Heart; Heart Failure; Humans; Imipramine; Nortriptyline; Tranquilizing Agents | 1971 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug Synergism; Female; Fever; Humans; Hypertension; Hypotension; Imipramine; Isocarboxazid; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Seizures | 1971 |
Comparative study of imipramine, amitriptyline and their desmethyl analogues in the hypothyroid rat.
Topics: Amitriptyline; Animals; Blepharoptosis; Desipramine; Exploratory Behavior; Female; Hypothyroidism; Imipramine; Motor Activity; Nortriptyline; Posture; Propylthiouracil; Psychopharmacology; Rats; Sympathomimetics; Tetrabenazine | 1967 |
Mechanism of inhibition of experimental inflammation by antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carrageenan; Catecholamines; Desipramine; Dextrans; Drug Synergism; Edema; Female; Formaldehyde; Imipramine; Nortriptyline; Rats | 1967 |
[On the management of pain using antidepressive agents].
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Nortriptyline; Pain | 1967 |
[Nortriptyline poisoning].
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Imipramine; Nortriptyline | 1967 |
Tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Nortriptyline; Opipramol | 1968 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents | 1968 |
[On the analgesic affect of thymoleptics].
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Codeine; Desipramine; Dibenzazepines; Humans; Imipramine; Male; Mice; Nortriptyline; Phosphates; Quinones; Tranquilizing Agents | 1968 |
[Investigation of gastric ulcer inhibiting and secreto-inhibitory actions of thymoleptics in rats].
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Gastric Juice; Imipramine; Nortriptyline; Rats; Stomach Ulcer | 1968 |
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine; Diazepam; Dibenzazepines; Drug Synergism; Ethanol; Humans; Imipramine; Methylphenidate; Mice; Nortriptyline; Phenelzine; Phenobarbital; Reflex; Substance-Related Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1968 |
Cardiac abnormalities in poisoning with tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Desipramine; Electrocardiography; Female; Heart; Humans; Imipramine; Nortriptyline | 1969 |
Desipramine.
Topics: Amitriptyline; Depression; Desipramine; Humans; Nortriptyline | 1965 |
Diagnosis and treatment of depressive reactions.
Topics: Antidepressive Agents; Depression; Desipramine; Humans; Nortriptyline | 1966 |
Methylation of desmethylimipramine by rabbit lung in vitro.
Topics: Animals; Antidepressive Agents; Carbon Isotopes; Chromatography, Paper; Desipramine; In Vitro Techniques; Lung; Male; Nortriptyline; Rabbits; Transferases | 1966 |
[Comparative clinical experiences with Protriptyline in depressive conditions of various origins].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Nortriptyline; Opipramol | 1966 |
[Restraining action of antidepressive agents of the imipramine group on the cardiovascular centers].
Topics: Action Potentials; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Blood Pressure; Carotid Arteries; Cats; Desipramine; Hypertension; Hypothalamus; Imipramine; Medulla Oblongata; Mesencephalon; Nictitating Membrane; Nortriptyline; Rats; Sciatic Nerve; Splanchnic Nerves | 1967 |
Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds.
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Imipramine; Male; Nortriptyline | 1967 |
[Clinical studies of a new antidepressive agent, nortriptyline].
Topics: Adolescent; Adult; Aged; Amitriptyline; Depression; Desipramine; Humans; Imipramine; Middle Aged; Neurotic Disorders; Nortriptyline | 1967 |
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine | 1980 |
In vitro metabolism in the rabbit of desipramine and nortriptyline to yield carboxylic acids.
Topics: Animals; Biotransformation; Carboxylic Acids; Desipramine; In Vitro Techniques; Liver; Mass Spectrometry; Nortriptyline; Rabbits | 1982 |
Potentiation of responses to adrenergic nerve stimulation in isolated rat atria during chronic tricyclic antidepressant administration.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Electric Stimulation; Heart Atria; In Vitro Techniques; Iprindole; Male; Muscles; Nerve Endings; Norepinephrine; Nortriptyline; Rats; Receptors, Adrenergic, alpha; Stimulation, Chemical; Sympathetic Nervous System | 1980 |
Interactions of tricyclic antidepressants with a synaptic ion channel.
Topics: Acetylcholine; Amitriptyline; Amphibian Venoms; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Desipramine; Electric Organ; Fishes; Imipramine; Ion Channels; Nortriptyline; Phencyclidine; Receptors, Nicotinic | 1981 |
Neuroendocrine dysfunction and response to tricyclic antidepressants.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dexamethasone; Evaluation Studies as Topic; Female; Humans; Hydrocortisone; Male; Middle Aged; Nortriptyline; Probability; Psychiatric Status Rating Scales; Retrospective Studies; Thyrotropin; Thyrotropin-Releasing Hormone | 1984 |
The nonlinear kinetics of desipramine and 2-hydroxydesipramine in plasma.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Chromatography, High Pressure Liquid; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Middle Aged; Nortriptyline; Random Allocation | 1984 |
Effect of tricyclic antidepressant drugs on lymphocyte membrane structure.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Membrane; Cells, Cultured; Desipramine; Dose-Response Relationship, Drug; Fluorescent Dyes; Imipramine; Lymphocytes; Male; Mice; Nortriptyline; Protriptyline; Spleen; Temperature; Time Factors | 1984 |
Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants.
Topics: Action Potentials; Adenosine; Animals; Antidepressive Agents, Tricyclic; Caffeine; Cerebral Cortex; Clomipramine; Desipramine; Drug Synergism; Iprindole; Male; Neurons; Nortriptyline; Rats; Rats, Inbred Strains | 1984 |
The complex binding of tricyclic antidepressants to rat brain: the case of nortriptyline.
Topics: Animals; Autoradiography; Binding Sites; Brain; Desipramine; Imipramine; Nortriptyline; Rats | 1984 |
Blood collection tubes for tricyclic antidepressant drugs: a reevaluation.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Preservation; Blood Proteins; Blood Specimen Collection; Desipramine; Humans; Imipramine; Nortriptyline; Plasma | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
Disputing preliminary findings on methylphenidate-desipramine responses.
Topics: Depressive Disorder; Desipramine; Humans; Methylphenidate; Nortriptyline; Probability | 1983 |
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline | 1983 |
Nortriptyline confused with Norpramin.
Topics: Desipramine; Humans; Medication Errors; Nortriptyline | 1983 |
Cimetidine interaction with imipramine and nortriptyline.
Topics: Adult; Biological Availability; Cimetidine; Desipramine; Drug Interactions; Humans; Imipramine; Kinetics; Male; Nortriptyline | 1984 |
The dexamethasone suppression test in depressive illness: clinical correlates.
Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxepin; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Male; Mianserin; Middle Aged; Nortriptyline; Phenelzine; Psychiatric Status Rating Scales; Selegiline | 1982 |
Column deactivation in analysis for underivatized tricyclic antidepressants by gas chromatography with use of a nitrogen detector.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Humans; Imipramine; Nitrogen; Nortriptyline | 1983 |
Complex inhibition of [3H]imipramine binding by serotonin and nontricyclic serotonin uptake blockers.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1983 |
The methylphenidate test for differentiating desipramine-responsive from nortriptyline-responsive depression.
Topics: Adolescent; Adult; Amitriptyline; Depressive Disorder; Desipramine; Emotions; Humans; Imipramine; Methylphenidate; Middle Aged; Norepinephrine; Nortriptyline | 1983 |
Plasma concentrations of tricyclic antidepressants in clinical practice.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Nortriptyline | 1982 |
Tricyclic antidepressants and cardiac patients with pacemakers.
Topics: Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Heart Rate; Humans; Imipramine; Male; Nortriptyline; Pacemaker, Artificial; Sick Sinus Syndrome | 1982 |
Tricyclic antidepressant plasma levels: the state of the art and clinical prospects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Imipramine; Nortriptyline | 1982 |
TCA-induced mania: differences between switchers and nonswitchers.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Protriptyline | 1982 |
Bonded-phase extraction of plasma tricyclic antidepressant drugs for gas chromatographic analysis.
Topics: Acetates; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Desipramine; Humans; Imipramine; Methods; Nortriptyline | 1982 |
The relationship of therapeutic response to antidepressant plasma levels: an update.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive Disorder; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Patient Compliance; Protriptyline | 1982 |
Evidence for in vivo methylation of the secondary amino antidepressant desipramine to imipramine in humans.
Topics: Amitriptyline; Biotransformation; Depressive Disorder; Desipramine; Humans; Imipramine; Methylation; Nortriptyline | 1982 |
Simultaneous liquid chromatographic analysis of amitriptyline, nortriptyline, imipramine, desipramine, doxepin, and nordoxepin.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline | 1981 |
Liquid-chromatographic analysis for common tricyclic antidepressant drugs and their metabolites in serum or plasma with the technicon "FAST-LC" system.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Protriptyline | 1981 |
The effects of antidepressants on the retention and metabolism of [3H]-norepinephrine in rat brain slices.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cocaine; Deamination; Desipramine; Dose-Response Relationship, Drug; In Vitro Techniques; Iprindole; Male; Norepinephrine; Nortriptyline; Protriptyline; Rats; Reserpine; Tritium | 1981 |
Cognitive improvement associated with tricyclic antidepressant treatment of childhood major depressive illness.
Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Cognition; Depressive Disorder; Desipramine; Female; Humans; Intelligence; Male; Nortriptyline; Psychiatric Status Rating Scales | 1981 |
Reversed-phase liquid chromatography and gas chromatography/mass fragmentography compared for determination of tricyclic antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Nortriptyline | 1981 |
Tricyclic antidepressant blood levels: eight practical questions.
Topics: Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Intestinal Absorption; Nortriptyline | 1981 |
Antidepressants inhibit enkephalin binding to synaptosome-enriched fractions of rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Synaptosomes; Viloxazine | 1981 |
Quantitative analysis for tricyclic antidepressant drugs in plasma or serum by gas chromatography-chemical-ionization mass spectrometry.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Female; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1980 |
An external quality-control scheme for tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Desipramine; Humans; Imipramine; Laboratories; Nortriptyline; Quality Control; United Kingdom | 1980 |
Traumatic dysesthesia of the trigeminal nerve.
Topics: Administration, Topical; Aged; Antidepressive Agents, Tricyclic; Capsaicin; Desipramine; Drug Therapy, Combination; Facial Pain; Female; Humans; Irritants; Male; Mandible; Mandibular Fractures; Nortriptyline; Paresthesia; Postoperative Complications; Rhytidoplasty; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 1994 |
A systematic assessment of tricyclic antidepressants in the treatment of adult attention-deficit hyperactivity disorder.
Topics: Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Comorbidity; Desipramine; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Medical Records; Nortriptyline; Treatment Outcome | 1995 |
Mixed mania: apparent induction by a tricyclic antidepressant in five consecutively treated patients with bipolar depression.
Topics: Adult; Bipolar Disorder; Desipramine; Female; Humans; Male; Middle Aged; Nortriptyline | 1995 |
Initiation of tricyclic treatment at full dose.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Administration Schedule; Humans; Hypotension, Orthostatic; Nortriptyline | 1994 |
Concurrent liquid chromatographic measurement of fluoxetine, amitriptyline, imipramine, and their active metabolites norfluoxetine, nortriptyline, and desipramine in plasma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Fluoxetine; Humans; Imipramine; Indicators and Reagents; Nortriptyline; Spectrophotometry, Ultraviolet | 1993 |
The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions.
Topics: Amitriptyline; Cryopreservation; Desipramine; Drug Overdose; Drug Stability; Embalming; Evaluation Studies as Topic; Forensic Medicine; Formaldehyde; Humans; Imipramine; Liver; Methylation; Nortriptyline; Poisoning; Temperature; Time Factors | 1993 |
Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome.
Topics: Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Female; Humans; Male; Nortriptyline; Tourette Syndrome; Treatment Outcome | 1993 |
Neuropathy associated with tricyclic antidepressants.
Topics: Alprazolam; Antidepressive Agents, Tricyclic; Desipramine; Female; Humans; Middle Aged; Nortriptyline; Peripheral Nervous System Diseases; Thyroxine | 1997 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Imipramine; Lung; Maprotiline; Mianserin; Microscopy, Electron; Nortriptyline; Organ Size; Perfusion; Pulmonary Edema; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley | 1997 |
Central NO is involved in the antinociceptive action of intracisternal antidepressants in freely moving rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Desipramine; Electric Stimulation; Electromyography; Enzyme Inhibitors; Imipramine; Jaw; Locomotion; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Nortriptyline; Rats; Rats, Sprague-Dawley; Reflex | 1998 |
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity | 1998 |
Isotope dilution gas chromatographic-mass spectrometric measurement of tricyclic antidepressant drugs. Utility of the 4-carbethoxyhexafluorobutyryl derivatives of secondary amines.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Deuterium; Drug Stability; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Nortriptyline; Reference Standards; Reproducibility of Results | 1998 |
Stability of tricyclic antidepressants in formalin solutions.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Drug Stability; Forensic Medicine; Formaldehyde; Imipramine; Nortriptyline; Substance Abuse Detection; Time Factors | 1998 |
Nonaqueous capillary electrophoretic separation and thermo-optical absorbance detection of five tricyclic antidepressants and metabolism of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Molecular Structure; Nortriptyline | 1998 |
Amitriptyline-induced loss of tight junction integrity in a human endothelial--smooth muscle cell bi-layer model.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Coculture Techniques; Desipramine; Electric Impedance; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Formazans; Humans; Imipramine; Muscle, Smooth, Vascular; Nortriptyline; Spectrometry, Fluorescence; Tetrazolium Salts; Tight Junctions; Umbilical Cord | 1999 |
Electrophysiologic analysis of antidepressant drug effects on the GABA(A) receptor complex based upon antagonist-induced encephalographic power spectrum changes.
Topics: Animals; Antidepressive Agents; Desipramine; Electroencephalography; Fluoxetine; Fourier Analysis; GABA Antagonists; Hippocampus; Imipramine; Male; Nortriptyline; Pentylenetetrazole; Rats; Rats, Wistar; Trazodone | 2000 |
Determination of residues in the norepinephrine transporter that are critical for tricyclic antidepressant affinity.
Topics: Amino Acid Sequence; Antidepressive Agents, Tricyclic; Binding Sites; Carrier Proteins; Cocaine; Desipramine; Dopamine; Molecular Sequence Data; Norepinephrine Plasma Membrane Transport Proteins; Nortriptyline; Symporters; Transfection | 2001 |
Comparison of noradrenergic and serotonergic antidepressants in reducing immobility time in the tail suspension test.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Fluoxetine; Fluvoxamine; Male; Models, Animal; Nortriptyline; Rats; Rats, Inbred Strains; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission; Tail | 2001 |
Sample preparation with fiber-in-tube solid-phase microextraction for capillary electrophoretic separation of tricyclic antidepressant drugs in human urine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Imipramine; Nortriptyline; Specimen Handling | 2001 |
NEWER ANTIDEPRESSANT DRUGS: DESIPRAMINE AND NORTRIPTYLINE.
Topics: Antidepressive Agents; Desipramine; Drug Therapy; Humans; Nortriptyline | 1965 |
THE DIAGNOSIS AND MANAGEMENT OF DEPRESSION.
Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Classification; Depression; Depressive Disorder; Desipramine; Diagnosis; Drug Therapy; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nortriptyline; Tyramine | 1965 |
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlorpromazine; Chlorprothixene; Desipramine; Eyelids; Imipramine; Mice; Nortriptyline; Peptic Ulcer; Pharmacology; Rats; Research; Reserpine; Toxicology; Tranquilizing Agents | 1964 |
PHARMACOLOGICAL PROPERTIES OF THE DESMETHYL DERIVATIVES OF SOME ANTIDEPRESSANTS OF IMIPRAMINE TYPE.
Topics: Amitriptyline; Animals; Antidepressive Agents; Caffeine; Desipramine; Hypothermia; Hypothermia, Induced; Imipramine; Injections, Intraperitoneal; Mice; Nortriptyline; Pentylenetetrazole; Peptic Ulcer; Rats; Research; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin; Strychnine; Toxicology; Tranquilizing Agents | 1965 |
Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines.
Topics: Adrenergic Uptake Inhibitors; Amines; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P450 Family 2; Desipramine; Diffusion; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Heme; Hydroxylation; Inhibitory Concentration 50; Kinetics; Liver; Male; Microsomes, Liver; Models, Chemical; NADP; Nortriptyline; Oxygen; Protein Binding; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Steroid 16-alpha-Hydroxylase; Steroids; Time Factors | 2003 |
Excess fatality from desipramine and dosage recommendations.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Databases, Factual; Desipramine; Drug Overdose; Humans; Imipramine; Nortriptyline; United Kingdom; United States | 2004 |
Excess fatality from desipramine in children and adolescents.
Topics: Adolescent; Amitriptyline; Child; Desipramine; Doxepin; Humans; Imipramine; Incidence; Mortality; Nortriptyline; Prevalence; Substance-Related Disorders | 2006 |
Rates of in vivo methylation of desipramine and nortriptyline.
Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Disorder; Desipramine; DNA Methylation; Drug Monitoring; Enzyme Inhibitors; Humans; Male; Methyltransferases; Nortriptyline; Retrospective Studies | 2006 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines | 2006 |
c-Fos expression identifies brain areas activated in response to nortriptyline.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Desipramine; Dose-Response Relationship, Drug; Male; Neurons; Nortriptyline; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Statistics, Nonparametric | 2007 |
Analysis of tricyclic antidepressant drugs in plasma by means of solid-phase microextraction-liquid chromatography-mass spectrometry.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Chromatography, Liquid; Clomipramine; Desipramine; Humans; Imipramine; Nortriptyline; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2007 |
In vitro biotransformation of amitriptyline and imipramine with rat hepatic S9 fraction: evaluation of the toxicity with Spirotox and Thamnotoxkit F Tests.
Topics: Amitriptyline; Animals; Anostraca; Biotransformation; Ciliophora; Desipramine; Imipramine; Lethal Dose 50; Liver; Male; Nortriptyline; Rats; Rats, Sprague-Dawley; Toxicity Tests; Water Pollutants, Chemical | 2008 |
IFN-gamma reduction by tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Cytokines; Depressive Disorder; Desipramine; Desvenlafaxine Succinate; Female; Humans; Imipramine; In Vitro Techniques; Interferon-gamma; Male; Nortriptyline; Venlafaxine Hydrochloride | 2010 |
Tricyclic antidepressants for the treatment of tenesmus associated with rectal prolapse.
Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Defecation; Desipramine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nortriptyline; Rectal Diseases; Rectal Prolapse; Retrospective Studies; Treatment Outcome | 2015 |
Quantification of Tricyclic Antidepressants in Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS).
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Nortriptyline; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |
The effects of prolonged administration of norepinephrine reuptake inhibitors on long-term potentiation in dentate gyrus, and on tests of spatial and object recognition memory in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Dentate Gyrus; Desipramine; Long-Term Potentiation; Male; Memory, Long-Term; Memory, Short-Term; Norepinephrine; Nortriptyline; Perforant Pathway; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Spatial Memory | 2016 |
Modulating cancer cell survival by targeting intracellular cholesterol transport.
Topics: Administration, Intravenous; Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Autophagy; bcl-2-Associated X Protein; Biological Transport; Cell Survival; Cholesterol; Desipramine; Endocytosis; Endosomes; Female; Flupenthixol; Fluphenazine; Gene Expression Regulation; Gene Knockdown Techniques; HCT116 Cells; Homeostasis; Humans; Inhibitory Concentration 50; Liposomes; Lysosomes; MCF-7 Cells; Melanoma; Mice; Nortriptyline; Perphenazine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingomyelin Phosphodiesterase; STAT3 Transcription Factor | 2017 |
β-Cyclodextrin Inclusion Complexation With Tricyclic Antidepressants Desipramine and Imipramine: A Structural Chemistry Perspective.
Topics: Antidepressive Agents, Tricyclic; beta-Cyclodextrins; Desipramine; Imipramine; Nortriptyline | 2020 |
Effects of the LC mobile phase in vacuum differential mobility spectrometry-mass spectrometry for the selective analysis of antidepressant drugs in human plasma.
Topics: Acetonitriles; Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Maprotiline; Mass Spectrometry; Methanol; Nortriptyline; Reproducibility of Results; Spectrum Analysis; Vacuum; Venlafaxine Hydrochloride | 2022 |
Antinociceptive effects of nortriptyline and desipramine hydrochloride in Speke's hinge-back tortoise (Kinixys Spekii).
Topics: Analgesics; Animals; Capsaicin; Desipramine; Formaldehyde; Nortriptyline; Pain; Turtles | 2023 |
On-Chip Electromembrane Surrounded Solid Phase Microextraction for Determination of Tricyclic Antidepressants from Biological Fluids Using Poly(3,4-ethylenedioxythiophene)-Graphene Oxide Nanocomposite as a Fiber Coating.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Limit of Detection; Maprotiline; Nanocomposites; Nortriptyline; Reproducibility of Results; Sertraline; Solid Phase Microextraction | 2023 |