desipramine and nomifensine

desipramine has been researched along with nomifensine in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-199046 (52.87)18.7374
1990's17 (19.54)18.2507
2000's10 (11.49)29.6817
2010's13 (14.94)24.3611
2020's1 (1.15)2.80

Authors

AuthorsStudies
Costanzo, MJ; Gardocki, JF; Maryanoff, BE; McComsey, DF; Nortey, SO; Schneider, CR; Setler, PE; Shank, RP1
Andrews, PR; Craik, DJ; Martin, JL1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Adkins, S; Duval, RA; Foster, JD; Hauck-Newman, A; Kulkarni, SS; Lever, JR; Parnas, ML; Sakrikar, DS; Vaughan, RA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bush, LR; Campbell, UC; Engel, SR; Hardy, LW; Hewitt, MC; Koch, P; Ma, J; Malcolm, SC; Saraswat, LD; Schreiber, R; Shao, L; Spear, KL; Spicer, NA; Varney, MA; Wang, F1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Tayo, FM1
Broch, OJ2
McEwen, J1
Fukuda, H; Hirobe, M; Nagao, T; Ohta, S; Ono, H; Satoh, M1
Männistö, PT; Törnwall, M1
Blaha, CD; Phillips, AG1
Schraven, E; Syha, K1
Badia, A; Sallés, J; Vila, E1
Campbell, IC; Ellison, DW1
Arai, Y; Kinemuchi, H; Kisara, K; Matsumura, T; Sakuma, I; Satoh, N; Tadano, T1
Hilakivi, I; Hilakivi, LA; Kiianmaa, K1
Allin, R; Reyneke, L; Russell, VA; Taljaard, JJ1
Curzon, G; Donohoe, TP; Hutson, PH1
Hilakivi, I; Hilakivi, LA; Loikas, P; Taira, T1
Lloyd, KG; Pilc, A; Thuret, F1
Altar, CA; Marshall, JF1
Borsini, F; d'Aranno, V; Lecci, A; Mancinelli, A; Meli, A1
Cubeddu, LX; Ferro, CP; Hoffmann, IS; Talmaciu, RK1
Ishida, Y; Kihara, M; Kobayashi, S; Koga, N; Nanbu, T1
Reyneke, L; Russell, VA; Taljaard, JJ1
Brochet, DM; Martin, P; Simon, P; Soubrié, P1
Roth, RH; Wolf, ME1
Cubeddu, LX; Hoffmann, IS; Talmaciu, RK1
Horn, ER; Hrdina, PD; Lapierre, YD1
Hetey, L; Zimmermann, B1
Jones, DJ; Stauderman, KA1
Cohen, O; Globus, M; Melamed, E; Rosenthal, J; Uzzan, A1
Jackson, DM; Jenkins, OF2
Fibiger, HC; Martin-Iverson, MT; Ortmann, R1
Jenner, P; Kelly, E; Marsden, CD1
Abel, D; Muscholl, E; Racké, K1
Jenner, P; Marsden, CD; Reavill, C1
Martin, S; Ortmann, R; Waldmeier, PC1
Bonanno, G; Marchi, M; Maura, G; Raiteri, M1
Fehr, B; Olpe, HR; Ortmann, R; Waldmeier, PC1
Bernasconi, S; Kostowski, W; Kozak, W; Valzelli, L1
Kametani, H; Nomura, S; Shimizu, J1
Siegfried, K; Taeuber, K1
Muscholl, E; Racké, K1
Schnieden, H; Stein, DM1
Devoize, JL; Eschalier, A; Pechadre, JC; Rigal, F1
Dupont, A; Merand, Y; Savard, P1
Lee, T; Tang, SW1
Blavet, N; DeFeudis, FV1
Waddington, JL1
Laakmann, G1
Cohen, G; Dembiec, D1
Hilakivi, I1
Bayer, BM; Berkeley, MB; Daussin, S; Hernandez, MC1
Boja, JW; Brouard, A; Carroll, FI; Kuhar, MJ; Pelaprat, D; Rostene, W; Vial, M1
Arai, Y; Kinemuchi, H; Kisara, K; Nakahata, N; Ohizumi, Y; Oshima, Y; Subarnas, A; Tadano, T1
Cohen, G; Evans, J1
Ahtee, L; Attila, LM; Hilakivi, I; Marjamaki, P; Rinne, JO; Taira, T1
Gerhardt, GA; Hebert, MA2
Dembiec-Cohen, D1
Tohda, M; Watanabe, H1
De Oliveira, K; Hennings, EC; Kiss, JP; Toth, PT; Vizi, ES1
Dongre, N; Eisenach, JC; Li, X; Pan, HL; Rose, G; Tobin, JR1
Balu, R; Davidson, C; Ellinwood, EH; Lee, TH1
Cao, J; Collins, AC; Grady, SR; Marks, MJ; McIntosh, JM; Murphy, KL1
Kirkbride, B; Mazei, MS; Pehek, EA; Pluto, CP1
Blaha, CD; Cooper, S; Harris, BT; Hitti, FL; Kim, U; Lee, KH; Leiter, JC; Roberts, DW1
Balaban, CD; Halberstadt, AL1
Nikiforuk, A; Popik, P1
Craft, RM; Kostick, ML; Rogers, JA; Tsutsui, KT; White, CL1
Buoli, M; Cahn, W; Serati, M1
Hettiarachchi, P; Johnson, MA1

Reviews

5 review(s) available for desipramine and nomifensine

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hypothesis: bromocriptine lacks intrinsic dopamine receptor stimulating properties.
    Journal of neural transmission, 1985, Volume: 62, Issue:3-4

    Topics: Adenylyl Cyclases; alpha-Methyltyrosine; Animals; Bromocriptine; Desipramine; Dextroamphetamine; Drug Interactions; Fluoxetine; Humans; Methyltyrosines; Mice; Motor Activity; Nialamide; Nomifensine; Nucleus Accumbens; Rats; Receptors, Dopamine; Reserpine; Stereotyped Behavior

1985
Pharmacodynamics of nomifensine: a review of studies in healthy subjects.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Administration, Oral; Adult; Arousal; Biological Availability; Cognition; Desipramine; Dose-Response Relationship, Drug; Electroencephalography; Emotions; Humans; Imipramine; Injections, Intravenous; Isoquinolines; Nomifensine; Prolactin; Psychomotor Performance; Sleep; Wakefulness

1984
Alternative pharmacological strategies for adult ADHD treatment: a systematic review.
    Expert review of neurotherapeutics, 2016, Volume: 16, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Amphetamines; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bupropion; Central Nervous System Stimulants; Desipramine; Dopamine Agents; Droxidopa; Drug Combinations; Duloxetine Hydrochloride; Guanfacine; Histamine Agents; Humans; Lisdexamfetamine Dimesylate; Lithium Compounds; Lobeline; Mecamylamine; Memantine; Modafinil; Morpholines; Nicotinic Agonists; Nicotinic Antagonists; Nomifensine; Paroxetine; Pyridines; Pyridoxine; Pyrrolidonecarboxylic Acid; Quinazolinones; Reboxetine; Venlafaxine Hydrochloride; Wakefulness-Promoting Agents

2016

Trials

1 trial(s) available for desipramine and nomifensine

ArticleYear
Influence of nomifensine and desipramine on tyramine pressor responses in healthy volunteers.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adult; Desipramine; Dose-Response Relationship, Drug; Humans; Isoquinolines; Male; Nomifensine; Sympathetic Nervous System; Tyramine

1977

Other Studies

81 other study(ies) available for desipramine and nomifensine

ArticleYear
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry; Dopamine; Isoquinolines; Male; Molecular Conformation; Motor Activity; Norepinephrine; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Synaptosomes; Tetrabenazine

1987
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter.
    The Journal of biological chemistry, 2007, Mar-23, Volume: 282, Issue:12

    Topics: Animals; Azides; Cocaine; Cyanogen Bromide; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epitopes; Humans; Iodine Radioisotopes; Methionine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Trypsin

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
    Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

    Topics: Animals; Antidepressive Agents; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Mice; Naphthalenes; Neurotransmitter Uptake Inhibitors; Norepinephrine; Serotonin

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effects of nomifensine on the isolated vas deferens of the rat.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 240, Issue:1

    Topics: Animals; Desipramine; Dopamine; Drug Interactions; Guanethidine; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Nomifensine; Norepinephrine; Phentolamine; Pimozide; Rats; Serotonin; Vas Deferens

1979
In vivo effects of benztropine and nomifensine on dopamine and noradrenaline terminals in rat brain.
    European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4

    Topics: Amphetamine; Animals; Benztropine; Brain; Corpus Striatum; Desipramine; Dopamine; Drug Interactions; Hydroxydopamines; Isoquinolines; Male; Nomifensine; Norepinephrine; Rats; Synaptosomes; Tropanes

1979
Amphetamine-antagonistic property of 4-phenyltetrahydroisoquinoline: effect on noradrenaline release in spinal cord slices.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:2

    Topics: Amphetamine; Animals; Desipramine; In Vitro Techniques; Isoquinolines; Male; Nomifensine; Norepinephrine; Potassium; Rats; Rats, Wistar; Spinal Cord; Synaptosomes; Tetrahydroisoquinolines

1992
Acute toxicity of three new selective COMT inhibitors in mice with special emphasis on interactions with drugs increasing catecholaminergic neurotransmission.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:1

    Topics: Amphetamine; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Clorgyline; Convulsants; Desipramine; Drug Interactions; Lethal Dose 50; Levodopa; Male; Mice; Motor Activity; Nitriles; Nomifensine; Pentanones; Selegiline; Synaptic Transmission; Yohimbine

1991
Application of in vivo electrochemistry to the measurement of changes in dopamine release during intracranial self-stimulation.
    Journal of neuroscience methods, 1990, Volume: 34, Issue:1-3

    Topics: Anesthesia; Animals; Brain; Desipramine; Dopamine; Electrochemistry; Male; Neurotransmitter Uptake Inhibitors; Nomifensine; Piperazines; Rats; Reward; Self Stimulation; Tegmentum Mesencephali

1990
Effects of a chronic administration of the new antidepressant pirlindole on biogenic amine receptors in rat prefrontal cortex and hippocampus. Comparison with desipramine, nomifensine and zimelidine.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:8

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Carbazoles; Cerebral Cortex; Desipramine; Hippocampus; Kinetics; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Neurotransmitter; Receptors, Serotonin; Thermodynamics; Zimeldine

1990
Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:3

    Topics: Animals; Antidepressive Agents; Cocaine; Desipramine; Electric Stimulation; Male; Mianserin; Muscle Contraction; Muscles; Nomifensine; Normetanephrine; Nortriptyline; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine

1990
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine

1986
Behavioral and biochemical changes following acute administration of MPTP and MPP+.
    Life sciences, 1987, Mar-30, Volume: 40, Issue:13

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Desipramine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Nomifensine; Pyridines; Pyridinium Compounds; Selegiline; Serotonin

1987
Neonatal antidepressant administration suppresses concurrent active (REM) sleep and increases adult alcohol consumption in rats.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1987, Volume: 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Animals, Newborn; Brain Chemistry; Desipramine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nomifensine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Sleep, REM; Zimeldine

1987
Lack of effect of chronic desipramine treatment on dopaminergic activity in the nucleus accumbens of the rat.
    Neurochemical research, 1989, Volume: 14, Issue:7

    Topics: Acetylcholine; Animals; Benzazepines; Desipramine; Dopamine; Dopamine Agents; Dopamine Antagonists; Electric Stimulation; Ergolines; Male; Nomifensine; Nucleus Accumbens; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Septal Nuclei; Spiperone

1989
Hypothermia induced by the putative 5-HT1A agonists LY165163 and 8-OH-DPAT is not prevented by 5-HT depletion.
    European journal of pharmacology, 1987, Nov-10, Volume: 143, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Brain; Desipramine; Fenclonine; Male; Naphthalenes; Nomifensine; Piperazines; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1987
Neonatal treatment with monoamine uptake inhibitors alters later response in behavioural 'despair' test to beta and GABA-B receptor agonists.
    Pharmacology & toxicology, 1988, Volume: 63, Issue:1

    Topics: Albuterol; Animals; Animals, Newborn; Antidepressive Agents; Baclofen; Behavior, Animal; Desipramine; gamma-Aminobutyric Acid; Male; Nomifensine; Rats; Rats, Inbred Strains; Time Factors; Zimeldine

1988
Upregulation of gamma-aminobutyric acid (GABA) B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Animals; Antidepressive Agents; Cerebral Cortex; Desipramine; Dose-Response Relationship, Drug; Electroshock; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin Antagonists; Time Factors; Viloxazine

1985
Striatal dopamine uptake and swim performance of the aged rat.
    Brain research, 1986, Jul-30, Volume: 379, Issue:1

    Topics: Aging; Animals; Bupropion; Corpus Striatum; Desipramine; Dopamine; Dopamine Antagonists; Male; Motor Activity; Nomifensine; Olfactory Bulb; Propiophenones; Rats; Rats, Inbred F344; Swimming

1986
Cholinergic drug effects on antidepressant-induced behaviour in the forced swimming test.
    European journal of pharmacology, 1988, Dec-13, Volume: 158, Issue:3

    Topics: Animals; Antidepressive Agents; Atropine; Behavior, Animal; Desipramine; Drug Synergism; Male; Motor Activity; Nomifensine; Pharmaceutical Vehicles; Physical Exertion; Physostigmine; Rats; Scopolamine; Swimming

1988
Sustained high release at rapid stimulation rates and reduced functional autoreceptors characterize prefrontal cortex dopamine terminals.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Animals; Apomorphine; Corpus Striatum; Desipramine; Dopamine; Electric Stimulation; Ergolines; Frontal Lobe; gamma-Aminobutyric Acid; In Vitro Techniques; Nomifensine; Norepinephrine; Quinpirole; Rabbits; Receptors, Dopamine; Serotonin

1988
4-Hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (PI-OH): a new potentiator of sympathomimetic amines on the rat anococcygeus muscle.
    British journal of pharmacology, 1988, Volume: 94, Issue:1

    Topics: Animals; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; In Vitro Techniques; Male; Muscles; Nomifensine; Propranolol; Rats; Rats, Inbred Strains; Sympathomimetics

1988
The modulatory effect of neurotensin on [3H]dopamine release from rat nucleus accumbens slices is enhanced after chronic desipramine treatment.
    Brain research, 1987, Nov-03, Volume: 425, Issue:1

    Topics: Animals; Apomorphine; Ascorbic Acid; Desipramine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Male; Neurotensin; Nomifensine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Time Factors; Tritium

1987
Acute effects of nomifensine on in vivo uptake and metabolism of dopamine, noradrenaline and serotonin in the rat brain.
    Pharmacology & toxicology, 1987, Volume: 60, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Desipramine; Dopamine; Imipramine; Injections, Intraventricular; Male; Nomifensine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin

1987
Triiodothyronine potentiation of antidepressant-induced reversal of learned helplessness in rats.
    Psychiatry research, 1987, Volume: 21, Issue:3

    Topics: Animals; Avoidance Learning; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Escape Reaction; Helplessness, Learned; Imipramine; Male; Nomifensine; Rats; Rats, Inbred Strains; Triiodothyronine

1987
Dopamine neurons projecting to the medial prefrontal cortex possess release-modulating autoreceptors.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: Animals; Cerebral Cortex; Desipramine; Dose-Response Relationship, Drug; Indoles; Male; Neurons; Nomifensine; Potassium; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Sulpiride

1987
Dopamine autoreceptors modulate dopamine release from the prefrontal cortex.
    Journal of neurochemistry, 1986, Volume: 47, Issue:3

    Topics: Animals; Apomorphine; Calcium; Desipramine; Dopamine; Electric Stimulation; Ergolines; Female; Frontal Lobe; Haloperidol; Male; Nomifensine; Quinpirole; Rabbits; Receptors, Dopamine

1986
Nomifensine overdose with TCAs and MAOIs.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:5

    Topics: Adult; Desipramine; Drug Interactions; Humans; Male; Nomifensine; Phenelzine

1986
Characterization of the synaptosomal high-affinity uptake of noradrenaline in the nucleus accumbens of rats.
    Biomedica biochimica acta, 1986, Volume: 45, Issue:9

    Topics: Animals; Biological Transport, Active; Desipramine; Dopamine; Kinetics; Male; Nomifensine; Norepinephrine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Synaptosomes

1986
Characterization of sodium-dependent, high-affinity serotonin uptake in rat spinal cord synaptosomes.
    Brain research, 1985, Mar-18, Volume: 330, Issue:1

    Topics: Animals; Desipramine; Fluoxetine; Kinetics; Male; Nomifensine; Rats; Rats, Inbred Strains; Serotonin; Sodium; Spinal Cord; Synaptosomes; Temperature

1985
Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP.
    European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Nomifensine; Norepinephrine; Pyridines; Serotonin Antagonists

1985
Bromocriptine potentiates the behavioural effects of directly and indirectly acting dopamine receptor agonists in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:1

    Topics: alpha-Methyltyrosine; Animals; Bromocriptine; Desipramine; Drug Synergism; Fluoxetine; Haloperidol; Levodopa; Male; Methyltyrosines; Mice; Motor Activity; Nomifensine; Receptors, Dopamine; Reserpine

1985
Place preference conditioning with methylphenidate and nomifensine.
    Brain research, 1985, Apr-15, Volume: 332, Issue:1

    Topics: Animals; Catecholamines; Central Nervous System; Desipramine; Dopamine; Drug Interactions; Haloperidol; Hydroxydopamines; Isoquinolines; Male; Methylphenidate; Motor Activity; Nomifensine; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Spatial Behavior

1985
Evidence that [3H]dopamine is taken up and released from nondopaminergic nerve terminals in the rat substantia nigra in vitro.
    Journal of neurochemistry, 1985, Volume: 45, Issue:1

    Topics: Amphetamine; Animals; Catecholamines; Corpus Striatum; Desipramine; Dopamine; Female; Fluoxetine; Hydroxydopamines; Medial Forebrain Bundle; Nerve Endings; Nomifensine; Oxidopamine; Potassium Chloride; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra; Synaptosomes

1985
Release and metabolism of [3H]dopamine in the neurointermediate lobe of the rat pituitary gland.
    Neuroscience, 1985, Volume: 16, Issue:3

    Topics: Animals; Deamination; Desipramine; Dopamine; Electric Stimulation; Hypothalamo-Hypophyseal System; Male; Methylation; Nomifensine; Oxidation-Reduction; Pargyline; Pituitary Gland, Posterior; Rats; Tetrodotoxin

1985
Metabolite involvement in bromocriptine-induced circling behaviour in rodents.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:4

    Topics: Amphetamine; Animals; Apomorphine; Biotransformation; Bromocriptine; Desipramine; Female; Hydroxydopamines; Male; Medial Forebrain Bundle; Methyltyrosines; Mice; Motor Activity; Nomifensine; Paralysis; Proadifen; Rats; Receptors, Dopamine; Receptors, Neurotransmitter; Reserpine; Sleep; Zoxazolamine

1980
Supersensitivity to L-5-hydroxytryptophan after 5,7-dihydroxytryptamine injections in desmethylimipramine- and nomifensine-pretreated rats: behavioral evidence for postsynaptic supersensitivity.
    Psychopharmacology, 1981, Volume: 74, Issue:2

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Brain Chemistry; Desipramine; Dihydroxytryptamines; Isoquinolines; Male; Methoxydimethyltryptamines; Neurotransmitter Agents; Nomifensine; Rats; Synapses

1981
Is there a functional linkage between neurotransmitter uptake mechanisms and presynaptic receptors?
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: Acetylcholine; Animals; Clomipramine; Clonidine; Cocaine; Desipramine; Dopamine; Hemicholinium 3; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Nomifensine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Synaptosomes

1984
Experimentally induced supersensitivity of neocortical neurons to microiontophoretically administered serotonin.
    Brain research, 1981, Nov-16, Volume: 224, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Animals; Cerebral Cortex; Desipramine; Hydroxyindoleacetic Acid; Iontophoresis; Microinjections; Neurons; Nomifensine; Rats; Serotonin

1981
Activity of desipramine, fluoxetine and nomifensine on spontaneous and p-CPA-induced muricidal aggression.
    Pharmacological research communications, 1984, Volume: 16, Issue:3

    Topics: Aggression; Animals; Antidepressive Agents; Desipramine; Fenclonine; Fluoxetine; Humans; Male; Nomifensine; Rats; Rats, Inbred Strains; Time Factors

1984
The reversal effect of antidepressants on the escape deficit induced by inescapable shock in rats.
    Psychopharmacology, 1983, Volume: 80, Issue:3

    Topics: Animals; Desipramine; Escape Reaction; Helplessness, Learned; Humans; Imipramine; Isoquinolines; Male; Nomifensine; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Adrenergic; Receptors, Dopamine

1983
Uptake of [3H]dopamine into dopaminergic and noradrenergic neurones of the isolated neurointermediate lobe of the rat hypophysis. Effects of desipramine and nomifensine.
    Journal of neurochemistry, 1983, Volume: 41, Issue:5

    Topics: Animals; Desipramine; Dopamine; Isoquinolines; Male; Neurons; Nomifensine; Norepinephrine; Pituitary Gland, Posterior; Rats

1983
Effect of antidepressant drugs on the in-vitro egg-penetrating ability of golden hamster epididymal spermatozoa.
    Journal of reproduction and fertility, 1983, Volume: 68, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Cricetinae; Desipramine; Female; Fertilization; Fertilization in Vitro; Male; Maleates; Mesocricetus; Mianserin; Nomifensine; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Viloxazine

1983
Activities of five antidepressants in a behavioral pain test in rats.
    Life sciences, 1983, Jun-27, Volume: 32, Issue:26

    Topics: Analgesia; Animals; Antidepressive Agents; Clomipramine; Desipramine; Electroshock; Male; Maprotiline; Nociceptors; Nomifensine; Rats; Rats, Inbred Strains; Viloxazine

1983
3H-mepyramine binding in various regions of rat brain following chronic treatment with different classes of antidepressant drugs.
    Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:4-6

    Topics: Aminopyridines; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Female; Iprindole; Nomifensine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1

1982
Reduced presynaptic dopamine receptor density after chronic antidepressant treatment in rats.
    Psychiatry research, 1982, Volume: 7, Issue:1

    Topics: Animals; Corpus Striatum; Desipramine; Dopamine; Isoquinolines; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Synapses

1982
Inhibition of foot intake in the rat.
    Neurochemical research, 1982, Volume: 7, Issue:3

    Topics: Animals; Antidepressive Agents; Appetite Depressants; Desipramine; Diazepam; Eating; Haloperidol; Imipramine; Male; Nomifensine; Rats; Rats, Inbred Strains

1982
Effects of nomifensine and desipramine on the sequelae of intracerebrally-injected 6-OHDA and 5,6-DHT.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:6

    Topics: 5,6-Dihydroxytryptamine; Animals; Apomorphine; Brain Chemistry; Desipramine; Dopamine; Humans; Hydroxydopamines; Isoquinolines; Male; Nomifensine; Rats; Serotonin; Stereotyped Behavior

1980
[Effect of antidepressants on the secretion of pituitary hormones in healthy subjects, neurotic depressive patients and endogenous depressive patients (author's transl)].
    Der Nervenarzt, 1980, Volume: 51, Issue:12

    Topics: Adult; Anthracenes; Clomipramine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Isoquinolines; Luteinizing Hormone; Male; Maprotiline; Middle Aged; Nomifensine; Pituitary Hormones, Anterior; Prolactin; Thyrotropin

1980
Potassium-induced release of [3H]catecholamine from brain: effects of pre-exposure to catecholamine uptake inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Acetophenones; Animals; Brain Chemistry; Catecholamines; Cocaine; Corpus Striatum; Desipramine; Dopamine; Drug Interactions; Imidazoles; In Vitro Techniques; Male; Mazindol; Nomifensine; Norepinephrine; Occipital Lobe; Potassium; Rats

1981
Early postnatal antidepressant treatment and juvenile stereotyped behaviour in rats.
    European journal of pharmacology, 1994, Dec-12, Volume: 271, Issue:1

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Apomorphine; Desipramine; Male; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Wistar; Stereotyped Behavior; Zimeldine

1994
In vitro effects of cocaine, lidocaine and monoamine uptake inhibitors on lymphocyte proliferative responses.
    Immunopharmacology and immunotoxicology, 1994, Volume: 16, Issue:2

    Topics: Animals; B-Lymphocytes; Cells, Cultured; Cocaine; Desipramine; Fluoxetine; Lidocaine; Lymphocyte Activation; Male; Mitogens; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes

1994
Potent cocaine analogs inhibit [3H]dopamine uptake in rat mesencephalic cells in primary cultures: pharmacological selectivity of embryonic cocaine sites.
    Brain research. Developmental brain research, 1993, Sep-17, Volume: 75, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport; Cell Membrane; Cells, Cultured; Cocaine; Desipramine; Dopamine; Embryo, Mammalian; Fluoxetine; Iodine Radioisotopes; Kinetics; Mesencephalon; Neurons; Nomifensine; Rats; Rats, Wistar; Stereoisomerism; Tritium

1993
A possible mechanism of antidepressant activity of beta-amyrin palmitate isolated from Lobelia inflata leaves in the forced swimming test.
    Life sciences, 1993, Volume: 52, Issue:3

    Topics: Animals; Antidepressive Agents; Desipramine; Immobilization; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Nomifensine; Norepinephrine; Oleanolic Acid; Oxidopamine; Plant Extracts; Swimming; Synaptosomes; Tetrabenazine; Triterpenes; Tritium

1993
Catecholamine uptake inhibitors elevate 6-hydroxydopamine in brain after administration of 6-hydroxydopa.
    European journal of pharmacology, 1993, Mar-02, Volume: 232, Issue:2-3

    Topics: Animals; Axons; Brain; Catecholamines; Cerebral Cortex; Chromatography, High Pressure Liquid; Desipramine; Dihydroxyphenylalanine; Membranes; Mice; Nerve Endings; Neurons; Nomifensine; Oxidopamine

1993
Effects of monoamine uptake inhibitors given early postnatally on monoamines in the brain stem, caudate/putamen and cortex, and on dopamine D1 and D2 receptors in the caudate/putamen.
    Journal of neural transmission. General section, 1995, Volume: 102, Issue:2

    Topics: Animals; Animals, Newborn; Binding, Competitive; Biogenic Monoamines; Brain Stem; Caudate Nucleus; Desipramine; Male; Monoamine Oxidase Inhibitors; Nomifensine; Putamen; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine; Zimeldine

1995
Normal and drug-induced locomotor behavior in aging: comparison to evoked DA release and tissue content in fischer 344 rats.
    Brain research, 1998, Jun-22, Volume: 797, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Aging; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Citalopram; Corpus Striatum; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Habituation, Psychophysiologic; Limbic System; Locomotion; Male; Nomifensine; Nucleus Accumbens; Potassium; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Substantia Nigra

1998
Mazindol, nomifensine and desmethylimipramine inhibit potassium-induced release of dopamine: effect of stimulus strength.
    Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:6-7

    Topics: Adrenergic Uptake Inhibitors; Animals; Corpus Striatum; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mazindol; Nomifensine; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley

1998
Age-related changes in the capacity, rate, and modulation of dopamine uptake within the striatum and nucleus accumbens of Fischer 344 rats: an in vivo electrochemical study.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Aging; Animals; Citalopram; Corpus Striatum; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Electrophysiology; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors

1999
Enhancement of serotonin 2C receptor mRNA expression by antidepressants possessing the receptor-blocking activity in the rat brain.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:4

    Topics: Animals; Antidepressive Agents; Brain; Desipramine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Imipramine; In Situ Hybridization; Male; Mianserin; Nomifensine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists

1998
Nicotinic acetylcholine receptor antagonistic activity of monoamine uptake blockers in rat hippocampal slices.
    Journal of neurochemistry, 1999, Volume: 73, Issue:3

    Topics: Animals; Culture Techniques; Desipramine; Electric Stimulation; Electrophysiology; Fluoxetine; Hippocampus; Male; Neurons; Neurotransmitter Uptake Inhibitors; Nicotinic Antagonists; Nomifensine; Norepinephrine; Rats; Rats, Wistar; Receptors, Nicotinic; Sodium Channels; Superior Cervical Ganglion; Tetrodotoxin

1999
S-nitroso-l-cysteine releases norepinephrine in rat spinal synaptosomes.
    Brain research, 2000, Jul-28, Volume: 872, Issue:1-2

    Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Calcium; Calmodulin; Cysteine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Egtazic Acid; Leucine; Magnesium; Male; Nickel; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Nomifensine; Norepinephrine; omega-Conotoxins; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Sodium; Spinal Cord; Synaptosomes

2000
Differential time-course profiles of dopamine release and uptake changes induced by three dopamine uptake inhibitors.
    Synapse (New York, N.Y.), 2001, Sep-15, Volume: 41, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Benzazepines; Brain Chemistry; Clomipramine; Cocaine; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sulpiride

2001
Characterization of nicotinic agonist-induced [(3)H]dopamine release from synaptosomes prepared from four mouse brain regions.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2

    Topics: Animals; Brain; Desipramine; Dopamine; Female; Mice; Mice, Inbred C57BL; Nicotinic Agonists; Nomifensine; Piperazines; Synaptosomes; Tritium

2002
Effects of catecholamine uptake blockers in the caudate-putamen and subregions of the medial prefrontal cortex of the rat.
    Brain research, 2002, May-17, Volume: 936, Issue:1-2

    Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Desipramine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Neostriatum; Nerve Tissue Proteins; Nomifensine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Symporters; Synaptic Transmission; Up-Regulation

2002
Dopamine efflux in the rat striatum evoked by electrical stimulation of the subthalamic nucleus: potential mechanism of action in Parkinson's disease.
    The European journal of neuroscience, 2006, Volume: 23, Issue:4

    Topics: Action Potentials; Animals; Behavior, Animal; Corpus Striatum; Desipramine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Female; Fluoxetine; Immunohistochemistry; In Vitro Techniques; Male; Nomifensine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Subthalamic Nucleus; Tyrosine 3-Monooxygenase

2006
Selective anterograde tracing of nonserotonergic projections from dorsal raphe nucleus to the basal forebrain and extended amygdala.
    Journal of chemical neuroanatomy, 2008, Volume: 35, Issue:4

    Topics: 5,7-Dihydroxytryptamine; Adrenergic Uptake Inhibitors; Amygdala; Animals; Axons; Biotin; Brain Mapping; Desipramine; Dextrans; Dopamine Uptake Inhibitors; Efferent Pathways; Male; Medial Forebrain Bundle; Mesencephalon; Neurotoxins; Neurotransmitter Agents; Nomifensine; Raphe Nuclei; Rats; Rats, Long-Evans; Septal Nuclei; Staining and Labeling; Substantia Innominata

2008
Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants.
    Psychoneuroendocrinology, 2011, Volume: 36, Issue:1

    Topics: Animals; Antidepressive Agents; Attention; Behavior, Animal; Citalopram; Cognition Disorders; Desipramine; Drug Administration Schedule; Fluoxetine; Male; Nomifensine; Rats; Rats, Sprague-Dawley; Stress, Psychological; Time Factors

2011
Forced swim test behavior in postpartum rats.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:4

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Desipramine; Female; Neurotransmitter Uptake Inhibitors; Nomifensine; Ovariectomy; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Sertraline; Stress, Physiological; Swimming

2010
Characterization of D3 Autoreceptor Function in Whole Zebrafish Brain with Fast-Scan Cyclic Voltammetry.
    ACS chemical neuroscience, 2022, 10-05, Volume: 13, Issue:19

    Topics: Animals; Autoreceptors; Brain; Carbon Fiber; Desipramine; Dopamine; Electric Stimulation; Mammals; Nomifensine; Norepinephrine Plasma Membrane Transport Proteins; Pramipexole; Receptors, Dopamine D2; Tetrahydronaphthalenes; Zebrafish

2022