desipramine and nicotine

desipramine has been researched along with nicotine in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (39.68)	18.7374
1990's	10 (15.87)	18.2507
2000's	21 (33.33)	29.6817
2010's	7 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM	1
Fei, YJ; Ganapathy, V; Kekuda, R; Leibach, FH; Prasad, PD; Wang, H; Wu, X	1
Giacomini, KM; Schaner, ME; Zhang, L	1
Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X	1
Conway, SJ; Ganapathy, V; George, RL; Huang, W; Leibach, FH; Wang, H; Wu, X	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Keserü, GM	1
Caron, G; Ermondi, G	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Dansette, PM; Fontana, E; Poli, SM	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Giordanetto, F; Leach, AG; Zachariae, U	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chiou, CY; Trzeciakowski, J	1
Chiba, S	3
Keatinge, WR; Torrie, C	1
Barron, KW; Chien, CY; Diana, JN; Heesch, CM; Qian, SF	1
McKay, DB	1
Daniels, AJ; Diliberto, EJ; Reinhard, JF; Viveros, OH	1
Davidson, RK; Dilsauer, SC; Hariharen, M	1
Goodman, FR; Weiss, GB	1
von Euler, US	1
Creech, BJ; Smith, KR	1
Bhagat, B; Friedman, E	1
Barker, JL; Crayton, JW; Nicoll, RA	1
Goodman, FR	1
Kuchii, M; Mori, J; Shibata, S	1
Ross, G	1
Bevan, JA; Su, C	2
Bhattacharya, IC; Goldstein, L; Pfeiffer, CC	1
Persson, NA; von Euler, US	1
Zetler, G	1
Oliverio, A	1
Jones, RS; Olpe, HR; Steinmann, MW	1
Andersson, A; Olsson, S; Tjälve, H	1
Schottenfeld, RS	1
Acosta, S; Au, D; Lutchmansingh, P; McCracken, JT; McGeoy, S; Poland, RE; Que, M	1
Ceña, V; Fernández-Fernández, JM; González-García, C; Izaguirre, V	1
Bizot, JC	1
Boyle, M; Cunningham, C; Jadad, AR; Kim, M; Schachar, R	1
Caboche, J; Girault, JA; Hervé, D; Pagès, C; Valjent, E	1
Bronius, PF; Brueggeman, RJ; Schoffelmeer, AN; van Gaalen, MM; Vanderschuren, LJ	1
Markou, A; Paterson, NE; Semenova, S	1

Reviews

3 review(s) available for desipramine and nicotine

Article	Year
The role of receptor binding in drug discovery. Journal of natural products, 1993, Volume: 56, Issue:4 Topics: Animals; Drug Design; Humans; Receptors, Drug	1993
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005
Treatment of attention-deficit/hyperactivity disorder. Evidence report/technology assessment (Summary), 1999, Issue:11 Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child Behavior; Combined Modality Therapy; Desipramine; Dextroamphetamine; Evidence-Based Medicine; Follow-Up Studies; Humans; Imipramine; Methylphenidate; Nicotine; Nicotinic Agonists; Pemoline; Phenylalanine; Placebos; Randomized Controlled Trials as Topic; Safety; Treatment Outcome	1999

Other Studies

60 other study(ies) available for desipramine and nicotine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. The Journal of biological chemistry, 1998, Jun-26, Volume: 273, Issue:26 Topics: Amino Acid Sequence; Animals; Cloning, Molecular; DNA-Binding Proteins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Octamer Transcription Factor-3; Oocytes; Placenta; Protein Conformation; Rats; Transcription Factors; Xenopus laevis	1998
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection	1998
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3 Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium	1999
Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochimica et biophysica acta, 2000, Jun-01, Volume: 1466, Issue:1-2 Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Proteins; Structure-Activity Relationship; Symporters; Tetraethylammonium; Tissue Distribution	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14 Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Histamine mediation of nicotine effects on postganglionic sympathetic neuroeffector junctions. Neuropharmacology, 1976, Volume: 15, Issue:11 Topics: Acetyl-CoA C-Acetyltransferase; Animals; Autonomic Fibers, Postganglionic; Chlorpheniramine; Desipramine; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuroeffector Junction; Nicotine; Pineal Gland; Pulmonary Artery; Rabbits; Rats; Sympathetic Nervous System; Tyramine	1976
Pharmacologic analysis of positive chronotropic and inotropic responses to octopamine. The Tohoku journal of experimental medicine, 1976, Volume: 118, Issue:3 Topics: Alprenolol; Animals; Desipramine; Dogs; Dopamine; Dose-Response Relationship, Drug; Female; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nicotine; Norepinephrine; Octopamine; Stimulation, Chemical; Tetrodotoxin	1976
Procaine-induced positive chronotropic and inotropic responses of the isolated, blood-perfused dog atrium. Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 225, Issue:1 Topics: Acetylcholine; Animals; Atropine; Desipramine; Dogs; Drug Interactions; Female; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Nicotine; Norepinephrine; Procaine; Propranolol; Stimulation, Chemical; Tetrodotoxin; Tyramine	1977
Action of sympathetic nerves of inner and outer muscle of sheep carotid artery, and effect of pressure on nerve distribution. The Journal of physiology, 1976, Volume: 257, Issue:3 Topics: Action Potentials; Animals; Carotid Arteries; Cyanides; Desipramine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Pressure; Sheep; Stimulation, Chemical; Vasomotor System	1976
Pharmacological analysis of dopamine action on the isolated dog atrium. The Tohoku journal of experimental medicine, 1975, Volume: 115, Issue:4 Topics: Alprenolol; Animals; Desipramine; Dogs; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Heart Atria; Heart Rate; In Vitro Techniques; Nicotine; Norepinephrine; Tetrodotoxin; Tyramine	1975
Nicotine-induced skeletal muscle vasodilation is mediated by release of epinephrine from nerve terminals. The American journal of physiology, 1990, Volume: 259, Issue:6 Pt 2 Topics: Adrenalectomy; Adrenergic Antagonists; Animals; Blood Vessels; Desipramine; Dogs; Epinephrine; Female; Ganglionic Blockers; Hemodynamics; Hindlimb; Male; Muscles; Nerve Endings; Nicotine; Norepinephrine; Parasympatholytics; Vasodilation	1990
[3H]noradrenaline accumulation in cultured bovine adrenal medullary cells: modulation of accumulation by nicotine. Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:6 Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Desipramine; Hexamethonium Compounds; Nicotine; Norepinephrine; Reserpine; Sympathetic Nervous System	1989
Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:22 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Cell Compartmentation; Cells, Cultured; Desipramine; Digitonin; Drug Interactions; Nicotine; Pyridines; Pyridinium Compounds; Subcellular Fractions; Tetrabenazine; Tyrosine 3-Monooxygenase	1987
Desipramine subsensitizes nicotinic mechanism involved in regulating core temperature. Psychiatry research, 1988, Volume: 25, Issue:1 Topics: Amitriptyline; Animals; Body Temperature Regulation; Brain; Desipramine; Fluoxetine; Light; Lithium; Male; Nicotine; Phenelzine; Rats; Rats, Inbred Strains; Receptors, Nicotinic	1988
Alteration of 5-hydroxytryptamine-14C efflux by nicotine in rat brain area slices. Neuropharmacology, 1973, Volume: 12, Issue:10 Topics: Animals; Bicarbonates; Brain; Calcium; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Corpus Striatum; Desipramine; Hydrazines; Hydroxyindoleacetic Acid; Hypothalamus; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Nicotine; Potassium; Procaine; Rats; Serotonin; Sodium; Sodium Isotopes; Temperature; Time Factors	1973
Effect of drugs on adrenergic nerve terminals. Advances in cytopharmacology, 1971, Volume: 1 Topics: Amines; Animals; Antidepressive Agents; Axons; Bretylium Compounds; Desipramine; Guanethidine; In Vitro Techniques; Membranes; Monoamine Oxidase Inhibitors; Nerve Endings; Neurotransmitter Agents; Nicotine; Norepinephrine; Reflex; Reserpine; Sulfhydryl Reagents; Sympathetic Nervous System; Sympatholytics; Synaptic Transmission; Tyramine	1971
Effects of pharmacological agents on the physiological responses of hair discs. Experimental neurology, 1967, Volume: 19, Issue:4 Topics: Acetylcholine; Action Potentials; Alkaloids; Amitriptyline; Animals; Anticonvulsants; Calcium; Catecholamines; Desipramine; Electric Stimulation; Hair; Imipramine; Lobeline; Magnesium; Monoamine Oxidase Inhibitors; Nicotine; Parasympathomimetics; Plants, Medicinal; Plants, Toxic; Potassium; Rats; Reserpine; Sensory Receptor Cells; Serotonin; Skin Physiological Phenomena; Synaptic Transmission; Touch; Veratrum	1967
Uptake of (3H)noradrenaline in the rat heart during increased sympathetic nervous activity associated with cold. The Journal of pharmacy and pharmacology, 1968, Volume: 20, Issue:12 Topics: Angiotensin II; Animals; Cocaine; Cold Temperature; Desipramine; Male; Myocardium; Nicotine; Norepinephrine; Rats; Tritium; Tyramine	1968
Noradrenaline and acetylcholine responses of supraoptic neurosecretory cells. The Journal of physiology, 1971, Volume: 218, Issue:1 Topics: Acetylcholine; Adrenergic beta-Antagonists; Alkaloids; Amino Alcohols; Anilides; Animals; Atropine; Carbachol; Cats; Depression, Chemical; Desipramine; Dopamine; Drug Synergism; Hypothalamo-Hypophyseal System; Hypothalamus; Methacholine Compounds; Nerve Endings; Neurosecretion; Nicotine; Norepinephrine; Physostigmine; Serotonin; Sulfonamides	1971
Effects of nicotine on distribution and release of 14C-norepinephrine and 14C-dopamine in rat brain striatum and hypothalamus slices. Neuropharmacology, 1974, Volume: 13, Issue:10-11 Topics: Animals; Calcium; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Corpus Striatum; Desipramine; Dopamine; Dopamine Antagonists; Hypothalamus; In Vitro Techniques; Kinetics; Male; Nicotine; Norepinephrine; Rats; Sodium	1974
Pharmacological nature of adrenergic innervation in rat aorta. Comparative and general pharmacology, 1973, Volume: 4, Issue:14 Topics: Animals; Aorta; Aorta, Thoracic; Autoradiography; Cocaine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Fluorescence; Histocytochemistry; Hydroxydopamines; In Vitro Techniques; Muscle Contraction; Nicotine; Norepinephrine; Rats; Sympathetic Nervous System; Time Factors; Tritium; Tyramine	1973
Effects of intracoronary infusions of acetylcholine and nicotine on the dog heart in vivo. British journal of pharmacology, 1973, Volume: 48, Issue:4 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Coronary Vessels; Desipramine; Dogs; Electric Stimulation; Heart; Heart Rate; Injections, Intra-Arterial; Nicotine; Phenoxybenzamine; Sympathetic Nervous System	1973
Uptake of nicotine by the sympathetic nerve terminals in the blood vessel. The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:3 Topics: Animals; Aorta; Autonomic Fibers, Postganglionic; Blood Vessels; Cocaine; Desipramine; Extracellular Space; Guanethidine; In Vitro Techniques; Muscle Contraction; Nerve Endings; Nicotine; Norepinephrine; Pulmonary Artery; Rabbits; Sympathetic Nervous System; Time Factors; Tritium	1972
Influence of acute and chronic nicotine administration on EEG reactivity to drugs in rabbits. 2. Psychoactive agents. Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Cerebral Cortex; Chlordiazepoxide; Deanol; Depression, Chemical; Desipramine; Electroencephalography; Injections, Subcutaneous; Male; Nicotine; Rabbits; Stimulation, Chemical; Time Factors	1970
Potentiation of adrenergic cardiovascular effects of two quaternary nicotine analogues by reserpine. Acta physiologica Scandinavica, 1970, Volume: 78, Issue:4 Topics: Animals; Blood Pressure; Cardiovascular System; Cats; Cell Membrane Permeability; Desipramine; Drug Antagonism; Drug Synergism; Heart Rate; Hexamethonium Compounds; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Prenylamine; Pyridinium Compounds; Reserpine	1970
Blockade of the nicotine-induced norepinephrine release by cocaine, phenoxybenzamine and desipramine. The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2 Topics: Action Potentials; Animals; Axons; Bretylium Compounds; Cocaine; Desipramine; Electric Stimulation; Guanethidine; Muscle Contraction; Nicotine; Norepinephrine; Phenoxybenzamine; Pulmonary Artery; Rabbits; Reserpine; Tetrodotoxin; Tritium	1970
Cataleptic state and hypothermia in mice, caused by central cholinergic stimulation and antagonized by anticholinergic and antidepressant drugs. International journal of neuropharmacology, 1968, Volume: 7, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Catalepsy; Desipramine; Hexamethonium Compounds; Humans; Hypothermia; Imipramine; Male; Mice; Nicotine; Nicotinic Acids; Nitrophenols; Parasympatholytics; Parasympathomimetics; Phosphoric Acids; Pilocarpine; Pralidoxime Compounds; Scopolamine; Tremorine	1968
Analysis of the "anti-fatigue" activity of amphetamine. Role of central adrenergic mechanisms. Il Farmaco; edizione scientifica, 1967, Volume: 22, Issue:6 Topics: Amphetamine; Animals; Avoidance Learning; Desipramine; Drug Antagonism; Escape Reaction; Fatigue; Methyltyrosines; Mice; Nicotine; Pargyline	1967
The locus coeruleus: actions of psychoactive drugs. Experientia, 1983, Mar-15, Volume: 39, Issue:3 Topics: Action Potentials; Animals; Atropine; Caffeine; Chlorpromazine; Desipramine; Haloperidol; Locus Coeruleus; Male; Neurons; Nicotine; Norepinephrine; Physostigmine; Psychotropic Drugs; Rats; Scopolamine	1983
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro. Acta pharmacologica et toxicologica, 1980, Volume: 47, Issue:1 Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature	1980
Clinical trials of pharmacologic treatments in pregnant women--methodologic considerations. NIDA research monograph, 1995, Volume: 149 Topics: Bromocriptine; Buprenorphine; Clinical Trials as Topic; Desipramine; Dopamine Agonists; Female; Humans; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Pregnancy; Pregnancy Complications; Research Design; Substance-Related Disorders	1995
Exposure to threshold doses of nicotine in utero: III. Augmentation of the prolactin and ACTH response to 8-OH DPAT by desipramine treatment is compromised in adult male offspring. Neurotoxicology, 1996,Summer, Volume: 17, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adrenocorticotropic Hormone; Animals; Desipramine; Drug Synergism; Female; Male; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Prolactin; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists	1996
Tricyclic antidepressants block cholinergic nicotinic receptors and ATP secretion in bovine chromaffin cells. FEBS letters, 1997, Nov-24, Volume: 418, Issue:1-2 Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Cattle; Cells, Cultured; Chromaffin Cells; Desipramine; Imipramine; Membrane Potentials; Nicotine; Nicotinic Antagonists; Potassium; Receptors, Nicotinic	1997
Effects of psychoactive drugs on temporal discrimination in rats. Behavioural pharmacology, 1997, Volume: 8, Issue:4 Topics: Animals; Atropine; Clomipramine; Desipramine; Diazepam; Discrimination Learning; Discrimination, Psychological; Haloperidol; Male; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar; Scopolamine	1997
Effectiveness of attention-deficit/hyperactivity treatment and diagnosis methods tested. Report on medical guidelines & outcomes research, 2000, Feb-17, Volume: 11, Issue:4 Topics: Adult; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Preschool; Comorbidity; Desipramine; Dextroamphetamine; Drug Therapy, Combination; Female; Humans; Lithium; Male; Methylphenidate; Nicotine; Pemoline; Phenylalanine	2000
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain. The European journal of neuroscience, 2004, Volume: 19, Issue:7 Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzazepines; Brain; Caffeine; Central Nervous System Stimulants; Cocaine; Desipramine; Dopamine Antagonists; Dronabinol; Enzyme Activation; Fluoxetine; Immunohistochemistry; Male; Mice; Mitogen-Activated Protein Kinases; Morphine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Scopolamine; Selective Serotonin Reuptake Inhibitors	2004
Behavioral disinhibition requires dopamine receptor activation. Psychopharmacology, 2006, Volume: 187, Issue:1 Topics: Amphetamine; Animals; Behavior, Animal; Benzazepines; Cocaine; Desipramine; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Nicotine; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine; Serotonin	2006
The effects of chronic versus acute desipramine on nicotine withdrawal and nicotine self-administration in the rat. Psychopharmacology, 2008, Volume: 198, Issue:3 Topics: Animals; Antidepressive Agents, Tricyclic; Conditioning, Operant; Depression; Desipramine; Food; Infusion Pumps, Implantable; Injections, Intravenous; Nicotine; Nicotinic Agonists; Rats; Reward; Self Administration; Self Stimulation; Substance Withdrawal Syndrome; Tobacco Use Disorder	2008