Compounds > desipramine

desipramine and nadp

desipramine has been researched along with nadp in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jonsson, J1
Hansson, T; Ingelman-Sundberg, M; Lundström, J; Marklund, M; Svensson, JO; von Bahr, C1
Orrenius, S; Schenkman, JB; von Bahr, C; Wilson, BJ1
Bellward, GD; Morgan, RG; Szombathy, VH1
Illing, HP; Kunke, S; Netter, KJ1
Bickel, MH; Gigon, PL1
Bickel, MH1
Athanassopoulos, S; Hellmer, KH; Murray, RE; Reiner, O; Uehleke, H1
Oates, JA; Shand, DG1
Najbar-Kaszkiel, AT; Rand, MJ1
Murray, M; Trieu, L1
Murray, K; Murray, M1

Reviews

1 review(s) available for desipramine and nadp

ArticleYear
On the significance of drug-induced spectral changes in liver microsomes.
    Biochemical Society symposium, 1972, Volume: 34

    Topics: Alkaloids; Amphetamine; Aniline Compounds; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Hydroxylation; Microsomes, Liver; NADP; Nortriptyline; Oxidoreductases; Phenacetin; Rats; Spectrum Analysis; Testosterone; Tryptophan

1972

Other Studies

11 other study(ies) available for desipramine and nadp

ArticleYear
On the aromatic hydroxylation of amphetamine in rat liver microsomes and perfused liver preparations: effects of long-term administration.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:4

    Topics: Administration, Oral; Amphetamines; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Desipramine; Fenfluramine; Hydroxylation; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Perfusion; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Time Factors

1977
Different regiospecificity in the hydroxylation of the antidepressant desmethylimipramine between rat brain and liver.
    Pharmacology & toxicology, 1992, Volume: 71, Issue:6

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Desipramine; Hydroxylation; Male; Microsomes, Liver; NADP; Peroxides; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide

1992
The effects of pretreatment of mice with norethindrone on the metabolism of 14C-imipramine by the liver microsomal drug-metabolizing enzymes.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:1

    Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cobalt; Cytochrome c Group; Cytochrome Reductases; Dealkylation; Desipramine; Female; Hydrogen-Ion Concentration; Hydroxylation; Imipramine; Methylcholanthrene; Mice; Microsomes, Liver; NADP; Norethindrone; Oxides; Phenobarbital; Proadifen; Time Factors

1974
On the spectral intermediate at 440 nm formed during mixed function substrate oxidation.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Acetanilides; Aniline Compounds; Animals; Barbiturates; Cytochrome P-450 Enzyme System; Desipramine; Imipramine; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Proadifen; Protein Binding; Rats; Spectrophotometry, Ultraviolet

1974
Metabolic interconversions and binding of imipramine, imipramine-N-oxide, and desmethylimipramine in rat liver slices.
    Xenobiotica; the fate of foreign compounds in biological systems, 1971, Volume: 1, Issue:6

    Topics: Animals; Cytosol; Dealkylation; Desipramine; Female; Imipramine; In Vitro Techniques; Liver; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Sex Factors; Temperature; Time Factors

1971
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. I. Tricyclic tertiary amine drugs.
    Archives of biochemistry and biophysics, 1972, Volume: 148, Issue:1

    Topics: Amitriptyline; Animals; Carbon Isotopes; Carbon Monoxide; Chlorpromazine; Cyclic N-Oxides; Cytochromes; Dealkylation; Desipramine; Horses; Imipramine; Kinetics; Liver; Male; NADP; Organ Specificity; Oxidation-Reduction; Proadifen; Rats; Species Specificity; Subcellular Fractions; Swine; Tetrazolium Salts

1972
[Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].
    Archiv fur Toxikologie, 1972, Volume: 29, Issue:3

    Topics: Alcohols; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Desipramine; Disulfiram; Flavonoids; Linoleic Acids; Lipid Metabolism; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Oxygenases; Piperonyl Butoxide; Rabbits; Rats; Ultraviolet Rays

1972
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine

1971
Effects of P2-receptor agonists on sympathetic neuroeffector transmission in the rat isolated anococcygeus muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Desipramine; Electric Stimulation; Enzyme Inhibitors; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NADP; NG-Nitroarginine Methyl Ester; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Thionucleotides

1998
Metabolite-intermediate complexation and inhibition of microsomal CYP3A in rat liver by diltiazem.
    Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Desipramine; Dexamethasone; Diltiazem; Enzyme Inhibitors; Immunoblotting; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Wistar; Spectrophotometry; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Testosterone

2000
Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines.
    Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:10

    Topics: Adrenergic Uptake Inhibitors; Amines; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P450 Family 2; Desipramine; Diffusion; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Heme; Hydroxylation; Inhibitory Concentration 50; Kinetics; Liver; Male; Microsomes, Liver; Models, Chemical; NADP; Nortriptyline; Oxygen; Protein Binding; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Steroid 16-alpha-Hydroxylase; Steroids; Time Factors

2003