Compounds > desipramine

desipramine and metyrapone

desipramine has been researched along with metyrapone in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (20.00)	18.7374
1990's	2 (20.00)	18.2507
2000's	2 (20.00)	29.6817
2010's	4 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Daniel, W; Netter, KJ	1
Illing, HP; Kunke, S; Netter, KJ	1
Athanassopoulos, S; Hellmer, KH; Murray, RE; Reiner, O; Uehleke, H	1
Cryan, JF; Harkin, A; Healy, DG; Kelly, JP; Leonard, BE	1
Cao, L; Filipov, NM; Lawrence, DA	1
Feinstein, DL; Garcia-Bueno, B; Hinojosa, AE; Leza, JC; Madrigal, JL; Polak, P	1

Reviews

1 review(s) available for desipramine and metyrapone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

9 other study(ies) available for desipramine and metyrapone

Article	Year
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Alteration of cytochrome P-450 by prolonged administration of imipramine and/or lithium to rats. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:2 Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Hexobarbital; Imipramine; Isoenzymes; Lithium; Liver; Male; Metyrapone; Rats; Rats, Inbred Strains	1990
On the spectral intermediate at 440 nm formed during mixed function substrate oxidation. Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18 Topics: Acetanilides; Aniline Compounds; Animals; Barbiturates; Cytochrome P-450 Enzyme System; Desipramine; Imipramine; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Proadifen; Protein Binding; Rats; Spectrophotometry, Ultraviolet	1974
[Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450]. Archiv fur Toxikologie, 1972, Volume: 29, Issue:3 Topics: Alcohols; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Desipramine; Disulfiram; Flavonoids; Linoleic Acids; Lipid Metabolism; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Oxygenases; Piperonyl Butoxide; Rabbits; Rats; Ultraviolet Rays	1972
Metyrapone displays antidepressant-like properties in preclinical paradigms. Psychopharmacology, 1999, Volume: 145, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Desipramine; Hyperkinesis; Hypothermia, Induced; Male; Metyrapone; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Swimming	1999
Sympathetic nervous system plays a major role in acute cold/restraint stress inhibition of host resistance to Listeria monocytogenes. Journal of neuroimmunology, 2002, Volume: 125, Issue:1-2 Topics: Acute Disease; Animals; Cold Temperature; Corticosterone; Desipramine; Enzyme Inhibitors; Immunity, Innate; Listeriosis; Male; Metyrapone; Mice; Mice, Inbred BALB C; Neuroimmunomodulation; Oxidopamine; Restraint, Physical; Stress, Physiological; Sympathectomy, Chemical; Sympathetic Nervous System; Sympatholytics	2002
Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs. Journal of neurochemistry, 2010, Volume: 113, Issue:2 Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Aldehyde-Lyases; Animals; Astrocytes; Benserazide; Brain; Chemokine CCL2; Corticosterone; Desipramine; Drug Administration Routes; Enzyme Inhibitors; Female; Gene Expression Regulation; Male; Metyrapone; Mice; Mice, Inbred C57BL; Norepinephrine; Propranolol; Rats; Rats, Wistar; Restraint, Physical; RNA, Messenger; Stress, Physiological	2010