desipramine and methamphetamine

desipramine has been researched along with methamphetamine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199013 (39.39)18.7374
1990's6 (18.18)18.2507
2000's10 (30.30)29.6817
2010's3 (9.09)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Chen, J; Conway, SJ; Fei, YJ; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wu, X1
Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X1
Caron, G; Ermondi, G1
Lombardo, F; Obach, RS; Waters, NJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carruba, MO; Mantegazza, P; Parenti, M; Picotti, GB; Ricciardi, S1
Prough, RA; Ziegler, DM1
Boura, AL; King, RG; Lau, WA1
Mandell, AJ; Spooner, CE; Wallach, MB; Winters, WD2
Ellaway, PH; Pascoe, JE1
Sofia, RD1
Christie, JE; Crow, TJ2
Dubnick, B; Rucki, EW; Salama, AI1
Grollman, A; Krishnamurty, VS1
Babbini, M; Cestari, A; De Marchi, F; Graziani, G1
Dénes, B; Greeff, K1
Glavin, GB; Hoaki, Y; Kohno, Y; Nagasaki, N; Tanaka, M; Tsuda, A1
McCann, MJ; Obert, JL; Rawson, RA; Shoptaw, S1
Hori, T; Nakane, H; Shimizu, N1
Misawa, M; Mori, T; Onodera, K; Suzuki, T; Tsuji, M1
Chou, J; Jeng, CH; Morales, M; Wang, JY; Wang, Y1
Kimura, H; Matsumoto, K; Mukaida, M; Wang, G; Yuan, J1
Gomita, Y; Nakagawa, T; Ohyama, T; Okamura, H; Ukai, K1
Glick, SD; Maisonneuve, IM; Shoblock, JR1
Matuszewich, L; Yamamoto, BK1
Crabbe, JC; Kliethermes, CL1
Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM1
Chetsawang, B; Govitrapong, P; Phansuwan-Pujito, P; Wisessmith, W1
Ago, Y; Hasebe, S; Hashimoto, H; Imoto, E; Matsuda, T; Takuma, K; Tanaka, T; Umehara, C1
Biagioni, F; Busceti, CL; Fabrizi, C; Ferrucci, M; Fornai, F; Giorgi, FS; Lazzeri, G; Lenzi, P; Morucci, G; Puglisi-Allegra, S1

Reviews

1 review(s) available for desipramine and methamphetamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for desipramine and methamphetamine

ArticleYear
The Matrix model of outpatient stimulant abuse treatment: evidence of efficacy.
    Journal of addictive diseases, 1994, Volume: 13, Issue:4

    Topics: Adult; Ambulatory Care; Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Methamphetamine; Neurologic Examination; Patient Care Team; Socioenvironmental Therapy; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome

1994

Other Studies

31 other study(ies) available for desipramine and methamphetamine

ArticleYear
Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.
    The Journal of biological chemistry, 1998, Dec-04, Volume: 273, Issue:49

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biogenic Monoamines; Brain; Carrier Proteins; Cell Line; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Neurotoxins; Neurotransmitter Agents; Oocytes; Rats; Xenopus laevis

1998
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium

1999
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effect of etoperidone on the depletion of brain 5-hydroxytryptamine and catecholamines induced respectively by p-chloromethamphetamine and 6-hydroxydopamine in rats.
    Pharmacological research communications, 1979, Volume: 11, Issue:2

    Topics: Animals; Antidepressive Agents; Brain; Catecholamines; Clomipramine; Desipramine; Dopamine; Hydroxydopamines; Male; Methamphetamine; Norepinephrine; Piperazines; Rats; Serotonin; Time Factors; Trazodone

1979
The relative participation of liver microsomal amine oxidase and cytochrome P-450 in N-demethylation reactions.
    Archives of biochemistry and biophysics, 1977, Apr-30, Volume: 180, Issue:2

    Topics: Amines; Aminopyrine; Aniline Compounds; Animals; Antibodies; Benzphetamine; Brompheniramine; Cricetinae; Cytochrome P-450 Enzyme System; Desipramine; Ephedrine; Male; Mesocricetus; Methamphetamine; Methimazole; Methylamines; Microsomes, Liver; Morphine Derivatives; NADPH-Ferrihemoprotein Reductase; Oxidoreductases Acting on CH-NH Group Donors; Rats; Swine

1977
Methoxyphenamine inhibits basal and histamine-induced nasal congestion in anaesthetized rats.
    British journal of pharmacology, 1990, Volume: 101, Issue:2

    Topics: Airway Resistance; Animals; Desipramine; Ephedrine; Epinephrine; Histamine Antagonists; Male; Methamphetamine; Methoxamine; Nasal Decongestants; Pentobarbital; Prazosin; Rats; Rats, Inbred Strains; Tyramine

1990
A correlation of EEG, reticular multiple unit activity and gross behavior following various antidepressant agents in the cat. IV.
    Electroencephalography and clinical neurophysiology, 1969, Volume: 27, Issue:6

    Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Cats; Chlorpromazine; Desipramine; Electroencephalography; Electromyography; Evoked Potentials; Female; Imipramine; Male; Mesencephalon; Methamphetamine; Pargyline; Perphenazine; Reticular Formation; Seizures; Sleep; Wakefulness

1969
Effects of antidepressant drugs on wakefulness and sleep in the cat.
    Electroencephalography and clinical neurophysiology, 1969, Volume: 27, Issue:6

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Chlorpromazine; Circadian Rhythm; Desipramine; Electromyography; Evoked Potentials; Female; Imipramine; Male; Mesencephalon; Methamphetamine; Pargyline; Perphenazine; Reticular Formation; Sleep; Sleep Stages; Time Factors; Wakefulness

1969
Noradrenaline as a transmitter in the spinal cord.
    The Journal of physiology, 1968, Volume: 197, Issue:1

    Topics: Animals; Catechols; Chlorpromazine; Cocaine; Desipramine; Electric Stimulation; Electrophysiology; Ergotamine; Methamphetamine; Norepinephrine; Phenoxybenzamine; Rabbits; Spinal Cord; Synaptic Transmission

1968
Structural relationship and potency of agents which selectively block mouse killing (muricide) behavior in rats.
    Life sciences, 1969, Nov-01, Volume: 8, Issue:21

    Topics: Aggression; Animals; Antidepressive Agents; Behavior, Animal; Central Nervous System Stimulants; Chlorpheniramine; Desipramine; Dextroamphetamine; Histamine H1 Antagonists; Humans; Imipramine; Methamphetamine; Mice; Pargyline; Rats; Tranylcypromine

1969
Behavioural studies of the actions of cocaine, monoamine oxidase inhibitors and iminodibenzyl compounds on central dopamine neurones.
    British journal of pharmacology, 1973, Volume: 47, Issue:1

    Topics: Amphetamine; Animals; Behavior, Animal; Catecholamines; Cocaine; Corpus Striatum; Desipramine; Dopamine; Drug Interactions; Male; Methamphetamine; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurons; Nialamide; Pargyline; Rats; Reserpine; Stereotaxic Techniques; Substantia Nigra; Time Factors

1973
A comparison of 1-p-acetyldeoxyephedrine and 4-methyl- -ethyl-m-tyramine as to lowering of brain serotonin, and their antagonism by antidepressants.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Acetates; Animals; Antidepressive Agents; Brain Chemistry; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Ephedrine; Female; Fluorometry; Imipramine; In Vitro Techniques; Methamphetamine; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Serotonin; Time Factors; Tritium

1973
Contractile response of rat aorta to norepinephrine and tyramine.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:2

    Topics: Amphetamine; Animals; Aorta, Thoracic; Cocaine; Desipramine; Dopamine; Drug Synergism; Electric Stimulation; Ephedrine; In Vitro Techniques; Methamphetamine; Muscle Contraction; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Time Factors; Tyramine

1972
Possible role of dopamine-containing neurones in the behavioural effects of cocaine.
    British journal of pharmacology, 1971, Volume: 42, Issue:4

    Topics: Animals; Cocaine; Desipramine; Dopamine; Drug Synergism; Ganglia, Autonomic; Methamphetamine; Motor Activity; Neurons; Nialamide; Norepinephrine; Rats

1971
Central nervous system activity of 1-(3-methoxypropylamino)-2-hydroxy-2-(1,4-benzodioxan-2-yl)-ethane hydrochloride.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:1

    Topics: Animals; Anxiety; Behavior, Animal; Caffeine; Central Nervous System; Chlorpromazine; Desipramine; Drug Synergism; Electroencephalography; Humans; Methamphetamine; Phenelzine; Rats; Reserpine; Reticular Formation; Sympatholytics; Thiopental

1967
Investigations on the mechanism of positive inotropic action of (+)-tranylcypromine in isolated guinea-pig atria.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:3

    Topics: Animals; Bupranolol; Desipramine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Myocardial Contraction; Nerve Endings; Reserpine; Stimulation, Chemical; Sympathetic Nervous System; Tranylcypromine; Tyramine

1984
Effects of altered brain noradrenaline level on acute stress pathology in rats.
    The Kurume medical journal, 1983, Volume: 30, Issue:2

    Topics: Animals; Brain; Desipramine; Male; Methamphetamine; Norepinephrine; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological

1983
Stress-induced norepinephrine release in the rat prefrontal cortex measured by microdialysis.
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2

    Topics: alpha-Methyltyrosine; Animals; Calcium; Carbolines; Desipramine; Diazepam; Electric Stimulation; Isotonic Solutions; Locus Coeruleus; Male; Methamphetamine; Methyltyrosines; Microdialysis; Norepinephrine; Potassium; Prefrontal Cortex; Rats; Rats, Wistar; Restraint, Physical; Ringer's Solution; Stress, Physiological; Tetrodotoxin

1994
Generalization of D-, L- and DL-chlorpheniramine and zolantidine to the discriminative stimulus effects of cocaine and methamphetamine.
    Behavioural pharmacology, 1997, Volume: 8, Issue:8

    Topics: Animals; Antidepressive Agents, Tricyclic; Benzothiazoles; Chlorpheniramine; Clomipramine; Cocaine; Desipramine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Methamphetamine; Middle Aged; Phenoxypropanolamines; Piperazines; Piperidines; Rats; Rats, Inbred F344; Thiazoles

1997
Chronic methamphetamine exposure decreases high affinity uptake function in norepinephrine afferents in the cerebellar cortex: an electrophysiological and electrochemical study.
    Neuropharmacology, 2000, Aug-23, Volume: 39, Issue:11

    Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; Animals; Cerebellar Cortex; Desipramine; gamma-Aminobutyric Acid; Isoproterenol; Male; Methamphetamine; Norepinephrine; Purkinje Cells; Rats; Rats, Sprague-Dawley

2000
Dual-label time-resolved fluoroimmunoassay of psychopharmaceuticals and stimulants in serum.
    Forensic science international, 2000, Sep-11, Volume: 113, Issue:1-3

    Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Calibration; Central Nervous System Stimulants; Chlorpromazine; Desipramine; Fluoroimmunoassay; Methamphetamine; Rabbits; Sensitivity and Specificity; Substance Abuse Detection; Toxicology

2000
Effect of dopaminergic drugs on the reserpine-induced lowering of hippocampal theta wave frequency in rats.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2000, Volume: 20, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Atropine; Bupropion; Cyclobutanes; Desipramine; Dopamine Agents; Dopamine Agonists; Hippocampus; Male; Methamphetamine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Reserpine; Theta Rhythm

2000
Differential interactions of desipramine with amphetamine and methamphetamine: evidence that amphetamine releases dopamine from noradrenergic neurons in the medial prefrontal cortex.
    Neurochemical research, 2004, Volume: 29, Issue:7

    Topics: Amphetamine; Animals; Desipramine; Dopamine; Female; Kinetics; Methamphetamine; Neurons; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin

2004
Effects of chronic stress on methamphetamine-induced dopamine depletions in the striatum.
    Annals of the New York Academy of Sciences, 2004, Volume: 1032

    Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Disease; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Male; Methamphetamine; Neostriatum; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Stress, Psychological

2004
Pharmacological and genetic influences on hole-board behaviors in mice.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 85, Issue:1

    Topics: Animals; Desipramine; Diazepam; Exploratory Behavior; Female; Fluoxetine; Male; Methamphetamine; Mice; Mice, Inbred Strains; Pentylenetetrazole; Piperazines; Selective Serotonin Reuptake Inhibitors

2006
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.
    Psychopharmacology, 2007, Volume: 195, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine

2007
Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells.
    Journal of pineal research, 2009, Volume: 46, Issue:4

    Topics: bcl-2-Associated X Protein; Caspase 3; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Desipramine; Drug Interactions; Humans; Melatonin; Methamphetamine; Microscopy, Fluorescence; Mitochondria; Neuroblastoma; Neuroprotective Agents; Signal Transduction

2009
Role of Prefrontal Serotonergic and Dopaminergic Systems in Encounter-Induced Hyperactivity in Methamphetamine-Sensitized Mice.
    The international journal of neuropsychopharmacology, 2017, 05-01, Volume: 20, Issue:5

    Topics: 5,7-Dihydroxytryptamine; Animals; Central Nervous System Stimulants; Desipramine; Dopamine; Dopamine Agents; Enzyme Inhibitors; Hyperkinesis; Locomotion; Male; Methamphetamine; Mice; Microdialysis; Oxidopamine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Serotonin; Serotonin Agents; Social Behavior; Time Factors

2017
Norepinephrine Protects against Methamphetamine Toxicity through β2-Adrenergic Receptors Promoting LC3 Compartmentalization.
    International journal of molecular sciences, 2021, Jul-05, Volume: 22, Issue:13

    Topics: Adrenergic Agents; Animals; Autophagy; Cell Compartmentation; Central Nervous System Stimulants; Desipramine; Dose-Response Relationship, Drug; Methamphetamine; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Models, Neurological; Neurons; Neuroprotective Agents; Norepinephrine; PC12 Cells; Rats; Receptors, Adrenergic, beta-2; Vacuoles

2021