desipramine and methadone

desipramine has been researched along with methadone in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (39.53)	18.7374
1990's	12 (27.91)	18.2507
2000's	8 (18.60)	29.6817
2010's	6 (13.95)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Mason, MF	1
Lin, HL; Medzihradsky, F	1
Evans, DB; Liu, SJ; Wang, RI	2
Chen, KZ; Liu, SJ; Wang, RI	1
Liu, SJ; Wang, RI	2
Brown, BS; Haertzen, CC; Jaffe, JH; Kolar, AF; Michaelson, BS; Weddington, WW	1
Brooke, D; Fudala, PJ; Johnson, RE	1
Arndt, IO; Dorozynsky, L; McLellan, AT; O'Brien, CP; Woody, GE	2
Falcione, J; Kosten, TR; Morgan, CM; Schottenfeld, RS	1
Meyer, RE	1
Kosten, TR; Morgan, CH; Schottenfeld, RS	1
Gawin, FH; Jatlow, P; Kosten, TR; Morgan, C; Nelson, JC	2
Arndt, IO; Burke, W; Dhopesh, V; Maany, I; O'Brien, CP; Woody, G	1
Arndt, I; Dorozynsky, L; McLellan, AT; O'Brien, CP; Woody, G	1
Alterman, A; Childress, AR; McLellan, AT; O'Brien, CP; Walter, D	1
Gawin, F; Kosten, T; Schumann, B	1
Baumann, P; Cuendet, C; Eap, CB	1
Carney, MK; Gawin, FH; Kosten, TR; Schumann, B; Wright, D	1
Affrime, M; Reidenberg, MM	1
Carmichael, FJ; Israel, Y	1
Garriott, JC; Stolman, A	1
Cleary, J; Kovera, CA; Overmier, JB; Schaal, DW; Thompson, T	1
Kosten, T; Leal, J; Ziedonis, D	1
Feingold, A; Kosten, TR; Oliveto, A; Schottenfeld, R	1
Feingold, A; Jatlow, P; Kosten, TR; Oliveto, AH; Schottenfeld, R	1
Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO	1
Gibert-Rahola, J; Mico, JA; Rojas-Corrales, MO	1
Patel, TA; Rastogi, R; Swarm, RA	1
Barak, Y; Baratz-Goldstein, R; Hostovsky, A; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I	1

Reviews

4 review(s) available for desipramine and methadone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug impairment reviews: opiates, minor tranquilizers. NIDA research monograph, 1977, Volume: Series 11 Topics: Amitriptyline; Anti-Anxiety Agents; Automobile Driving; Behavior; Desipramine; Dextropropoxyphene; Diazepam; Ethanol; Humans; Imipramine; Lithium; Methadone; Motor Skills; Narcotics; Task Performance and Analysis	1977
New pharmacotherapies for cocaine dependence ... revisited. Archives of general psychiatry, 1992, Volume: 49, Issue:11 Topics: Alcoholism; Cocaine; Desipramine; Disease Models, Animal; Double-Blind Method; Heroin Dependence; Humans; Methadone; Randomized Controlled Trials as Topic; Substance-Related Disorders	1992
Case scenario: opioid association with serotonin syndrome: implications to the practitioners. Anesthesiology, 2011, Volume: 115, Issue:6 Topics: Analgesics, Opioid; Antidepressive Agents, Tricyclic; Celecoxib; Chronic Pain; Cyclooxygenase 2 Inhibitors; Depressive Disorder; Desipramine; Drug Interactions; Duloxetine Hydrochloride; Fentanyl; Humans; Male; Methadone; Middle Aged; Oxycodone; Polypharmacy; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Sulfonamides; Thiophenes; Transdermal Patch	2011

Trials

11 trial(s) available for desipramine and methadone

Article	Year
Treatment of cocaine dependence in methadone maintenance clients: a pilot study comparing the efficacy of desipramine and amantadine. The International journal of the addictions, 1992, Volume: 27, Issue:7 Topics: Adolescent; Adult; Amantadine; Baltimore; Cocaine; Desipramine; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Pilot Projects; Placebos; Research Design; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Substance-Related Disorders; United States	1992
Weighing up the pros and cons: help-seeking by drug misusers in Baltimore, USA. Drug and alcohol dependence, 1992, Volume: 31, Issue:1 Topics: Adult; Bromocriptine; Buprenorphine; Cocaine; Desipramine; Fear; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Motivation; Opioid-Related Disorders; Patient Acceptance of Health Care; Phencyclidine Abuse; Substance Abuse Treatment Centers; Substance-Related Disorders; Urban Population	1992
Desipramine treatment of cocaine dependence in methadone-maintained patients. Archives of general psychiatry, 1992, Volume: 49, Issue:11 Topics: Adult; Cocaine; Comorbidity; Desipramine; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Patient Dropouts; Placebos; Severity of Illness Index; Substance Abuse Detection; Substance-Related Disorders; Treatment Outcome	1992
Pharmacotherapy for cocaine-abusing methadone-maintained patients using amantadine or desipramine. Archives of general psychiatry, 1992, Volume: 49, Issue:11 Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioid-Related Disorders; Placebos; Substance Abuse Detection; Substance-Related Disorders; Treatment Outcome	1992
Amantadine and desipramine in the treatment of cocaine abusing methadone maintained patients. NIDA research monograph, 1990, Volume: 105 Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioid-Related Disorders; Substance-Related Disorders	1990
Desipramine treatment of cocaine abuse in methadone maintenance patients. NIDA research monograph, 1989, Volume: 95 Topics: Clinical Trials as Topic; Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Humans; Male; Methadone; Opioid-Related Disorders; Substance-Related Disorders	1989
Evaluation of treatment for cocaine dependence. NIDA research monograph, 1989, Volume: 95 Topics: Adult; Behavior Therapy; Cocaine; Combined Modality Therapy; Desipramine; Double-Blind Method; Humans; Male; Methadone; Randomized Controlled Trials as Topic; Substance-Related Disorders; Veterans	1989
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. Drug and alcohol dependence, 1994, Volume: 35, Issue:1 Topics: Adult; Amantadine; Antisocial Personality Disorder; Cocaine; Combined Modality Therapy; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Method; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; Patient Dropouts; Substance Abuse Detection; Substance-Related Disorders	1994
Desipramine treatment for cocaine dependence. Role of antisocial personality disorder. The Journal of nervous and mental disease, 1994, Volume: 182, Issue:3 Topics: Adult; Antisocial Personality Disorder; Cocaine; Comorbidity; Desipramine; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Personality Inventory; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Substance-Related Disorders; Treatment Outcome	1994
Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers. The American journal on addictions, 2002,Spring, Volume: 11, Issue:2 Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Buprenorphine; Clinical Trials as Topic; Cocaine-Related Disorders; Cross-Over Studies; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Placebos; Time Factors; Treatment Outcome	2002
Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. Archives of general psychiatry, 1999, Volume: 56, Issue:9 Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Buprenorphine; Cocaine-Related Disorders; Comorbidity; Desipramine; Drug Administration Schedule; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Sex Factors; Treatment Outcome	1999

Other Studies

28 other study(ies) available for desipramine and methadone

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Inhibition of cellular atp-hydrolyzing activity by tricyclic antidepressants and phenothiazine tranquilizers. Life sciences, 1975, May-01, Volume: 16, Issue:9 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amphetamine; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Blood Platelets; Brain; Cattle; Desipramine; Kidney Cortex; Leukocytes; Male; Methadone; Microsomes; Neurons; Phenothiazines; Rats; Structure-Activity Relationship	1975
Correlation of urinary excretion of methadone metabolites with methadone metabolism and analgesia in the rat. The Journal of pharmacology and experimental therapeutics, 1978, Volume: 204, Issue:1 Topics: Analgesics; Animals; Biotransformation; Desipramine; Diazepam; Drug Interactions; Male; Methadone; Phenobarbital; Rats; Reaction Time; Time Factors; Tissue Distribution	1978
Determination of urinary excretion of a methadone metabolite as an indirect measurement of methadone metabolism in the rat. Toxicology and applied pharmacology, 1978, Volume: 44, Issue:3 Topics: Animals; Desipramine; Liver; Male; Methadone; Phenobarbital; Rats; Time Factors	1978
Effects of desipramine treatment on the biliary, fecal and urinary excretion of methadone in the rat. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:2 Topics: Animals; Bile; Desipramine; Feces; Male; Methadone; Rats; Time Factors	1976
Increased analgesia and alterations in distribution and metabolism of methadone by desipramine in the rat. The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:1 Topics: Analgesia; Animals; Brain; Desipramine; Drug Synergism; In Vitro Techniques; Kidney; Lethal Dose 50; Liver; Lung; Male; Methadone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Reaction Time; Time Factors	1975
Evidence for altered desipramine disposition in methadone-maintained patients treated for cocaine abuse. The American journal of drug and alcohol abuse, 1990, Volume: 16, Issue:3-4 Topics: Adult; Cocaine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Middle Aged; Substance-Related Disorders	1990
Desipramine and its 2-hydroxy metabolite in patients taking or not taking methadone. The American journal of psychiatry, 1990, Volume: 147, Issue:10 Topics: Desipramine; Drug Interactions; Humans; Hydroxylation; Methadone; Opioid-Related Disorders	1990
Increase in desipramine serum levels associated with methadone treatment. The American journal of psychiatry, 1989, Volume: 146, Issue:12 Topics: Adult; Cocaine; Desipramine; Drug Interactions; Drug Therapy, Combination; Humans; Male; Methadone; Opioid-Related Disorders; Substance-Related Disorders	1989
Treating cocaine abusing methadone maintenance patients with desipramine. NIDA research monograph, 1988, Volume: 81 Topics: Acquired Immunodeficiency Syndrome; Adult; Cocaine; Desipramine; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Substance-Related Disorders	1988
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2 Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine	1988
A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients. The Journal of clinical psychiatry, 1987, Volume: 48, Issue:11 Topics: Adult; Antisocial Personality Disorder; Black or African American; Cocaine; Desipramine; Female; Humans; Male; Methadone; Opioid-Related Disorders; Substance-Related Disorders	1987
Enhanced development of dispositional tolerance to methadone by desipramine given together with methadone. Life sciences, 1985, Feb-25, Volume: 36, Issue:8 Topics: Analgesia; Animals; Desipramine; Drug Interactions; Humans; Male; Methadone; Rats; Rats, Inbred Strains; Substance-Related Disorders; Time Factors	1985
Influence of disease on binding of drugs to plasma proteins. Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226 Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Proteins; Blood Urea Nitrogen; Carbon Radioisotopes; Creatinine; Dapsone; Desipramine; Dialysis; Fluoresceins; Heart Failure; Humans; Hypoproteinemia; Liver Cirrhosis; Male; Methadone; Pharmaceutical Preparations; Phenytoin; Protein Binding; Quinidine; Triamterene; Ultrafiltration; Uremia	1973
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2 Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium	1973
Detection of some psychotherapeutic drugs and their metabolites in urine. Clinical toxicology, 1971, Volume: 4, Issue:2 Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine	1971
Behavioral and neurochemical mechanisms of opioid-antidepressant interactions. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:1 Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Columbidae; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Endorphins; Female; Imipramine; Methadone; Norepinephrine; Reinforcement Schedule	1994
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates. Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3 Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; Desipramine; Fluvoxamine; Levorphanol; Male; Methadone; Mice; Morphine; Narcotics; Reserpine; Stereoisomerism; Time Factors; Tramadol; Venlafaxine Hydrochloride	2004
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior. Psychopharmacology, 2007, Volume: 190, Issue:2 Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Indophenol; Levorphanol; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Stereotyped Behavior; Tics; Tourette Syndrome; Tramadol; Triazoles	2007
Interaction of different antidepressants with acute and chronic methadone in mice, and possible clinical implications. Journal of molecular neuroscience : MN, 2014, Volume: 52, Issue:4 Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Citalopram; Clomipramine; Cyclohexanols; Desipramine; Drug Interactions; Fluvoxamine; Male; Methadone; Mice; Mice, Inbred ICR; Morpholines; Nociception; Pain Threshold; Reboxetine; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride	2014