desipramine has been researched along with melatonin in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (50.00) | 18.7374 |
| 1990's | 10 (23.81) | 18.2507 |
| 2000's | 3 (7.14) | 29.6817 |
| 2010's | 8 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Klein, DC; Parfitt, A | 1 |
| Checkley, SA; Dawling, S; Palazidou, E; Papadopoulos, A; Ratcliff, H | 1 |
| Durlach-Misteli, C; Van Ree, JM | 1 |
| Brown, GM; Kennedy, SH | 1 |
| Kuchel, GA; Zigmond, RE | 1 |
| Areso, PM; Dubocovich, ML; Mogilnicka, E | 1 |
| Arendt, J; Bearn, J; Checkley, SA; Franey, C | 1 |
| Braddock, LE; Cowen, PJ; Grahame-Smith, DG; Green, AR | 1 |
| Lewy, AJ; Sack, RL | 1 |
| Arendt, J; Checkley, SA; Corn, TH; Franey, C; Glass, IB; Thompson, C | 1 |
| Cowdry, RW; Golden, RN; Markey, SP; Potter, WZ; Risby, ED; Rudorfer, MV | 1 |
| Chen, YC; Reiter, RJ; Wu, WT | 1 |
| Brown, GM; Seggie, J | 1 |
| Amsterdam, J; Brown, R; Caroff, S; Frazer, A; Kocsis, J; Stokes, P; Sweeney, J; Winokur, A | 1 |
| Cozzi, B; Li, K; Oaknin, S; Reiter, RJ; Troiani, ME; Vaughan, GM | 1 |
| Aldhous, M; Arendt, J; Burton, S; Checkley, S; Franey, C | 1 |
| Coggins, SH; Lasko, J; Mason, AD; Pruitt, BA; Vaughan, GM | 1 |
| Arendt, J; Burton, S; Checkley, SA; Franey, C; Thompson, C | 1 |
| Amsterdam, J; Brown, RP; Caroff, S; Frazer, A; Kocsis, JH; Stokes, P; Winokur, A | 1 |
| Arendt, J; Checkley, SA; Corn, T; English, J; Franey, C; Mezey, G; Thompson, C | 1 |
| Anton-Tay, F; Axelrod, J; Wurtman, RJ | 1 |
| Cowen, PJ; Fraser, S; Grahame-Smith, DG; Green, AR; Stanford, C | 1 |
| Arendt, J; Checkley, SA; Corn, T; Franey, C; Thompson, C | 1 |
| Brunswick, DJ; Frazer, A; Heydorn, WE | 1 |
| Hirschmann, N; Nir, I | 1 |
| Halbreich, U; Klein, DF; Quitkin, FM; Stewart, J; Weinberg, U; Weitzman, ED | 1 |
| Arendt, J; Bojkowski, CJ; Skene, DJ | 1 |
| Hong, SM; Ramirez, J; Rollag, MD; Stetson, MH | 1 |
| Brown, GM; Joffe, R; Singer, W | 1 |
| Daya, S; Walsh, HA | 1 |
| Dragunow, M; MacGibbon, G; Walton, M; Woodgate, A | 1 |
| Barden, N; Labbé, M; Mocaër, E; Rochford, J; Shink, E; Vacher, R | 1 |
| Chetsawang, B; Chetsawang, J; Govitrapong, P | 1 |
| Chetsawang, B; Govitrapong, P; Phansuwan-Pujito, P; Wisessmith, W | 1 |
| Coburn, KL; Doonan, SM; Lauterbach, EC; Mendez, MF; Shillcutt, SD; Victoroff, J | 1 |
| Brink, CB; Ellis, SM; Harvey, BH; Mokoena, ML; Viljoen, F | 1 |
1 review(s) available for desipramine and melatonin
| Article | Year |
|---|---|
Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipsychotic Agents; Benzodiazepines; Benzothiazoles; Brain; Clonazepam; Desipramine; Dibenzothiazepines; Dopamine Agonists; Humans; Lithium Carbonate; Maprotiline; Melatonin; Neurodegenerative Diseases; Neuroprotective Agents; Olanzapine; Parkinson Disease; Pramipexole; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2010 |
4 trial(s) available for desipramine and melatonin
| Article | Year |
|---|---|
Antidepressants reduce whole-body norepinephrine turnover while enhancing 6-hydroxymelatonin output.
Topics: Adult; Animals; Antidepressive Agents; Bupropion; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Mice; Middle Aged; Norepinephrine; Propiophenones; Tranylcypromine | 1988 |
Acute treatment with desipramine stimulates melatonin and 6-sulphatoxy melatonin production in man.
Topics: Adult; Desipramine; Female; Humans; Male; Melatonin; Radioimmunoassay; Time Factors | 1986 |
Clinical studies of the effect of (+) and (-)-oxaprotiline upon noradrenaline uptake.
Topics: Anthracenes; Antidepressive Agents; Desipramine; Humans; Male; Maprotiline; Melatonin; Norepinephrine; Pupil; Stereoisomerism | 1985 |
Comparison of the effects of acute fluvoxamine and desipramine administration on melatonin and cortisol production in humans.
Topics: Adult; Analysis of Variance; Desipramine; Fluvoxamine; Humans; Hydrocortisone; Male; Melatonin; Radioimmunoassay | 1994 |
37 other study(ies) available for desipramine and melatonin
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Increase caused by desmethylimipramine in the production of [3H]melatonin by isolated pineal glands.
Topics: Acetyltransferases; Animals; Desipramine; Drug Interactions; Epinephrine; Humans; In Vitro Techniques; Male; Melatonin; Norepinephrine; Pineal Gland; Rats; Stimulation, Chemical; Tryptophan | 1977 |
Noradrenaline uptake inhibition increases melatonin secretion, a measure of noradrenergic neurotransmission, in depressed patients.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Middle Aged; Norepinephrine; Personality Inventory; Receptors, Adrenergic; Synaptic Transmission | 1992 |
Dopamine and melatonin in the nucleus accumbens may be implicated in the mode of action of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluvoxamine; Male; Melatonin; Mianserin; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Dopamine; Sensitivity and Specificity | 1992 |
Effect of chronic antidepressant treatment with adinazolam and desipramine on melatonin output.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Depressive Disorder; Desipramine; Female; Humans; Melatonin; Middle Aged; Personality Inventory; Pineal Gland | 1992 |
Functional recovery and collateral neuronal sprouting examined in young and aged rats following a partial neural lesion.
Topics: Aging; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Desipramine; Functional Laterality; Male; Melatonin; Neuronal Plasticity; Norepinephrine; Pineal Gland; Rats; Rats, Inbred F344; Rats, Inbred Strains; Reference Values; Sympathectomy | 1991 |
Antidepressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in the mouse behavioral despair test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Calcium; Cerebral Cortex; Desipramine; Dose-Response Relationship, Drug; Male; Melatonin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Motor Activity; Norepinephrine; Receptors, Melatonin; Receptors, Neurotransmitter; Tryptamines | 1990 |
A study of the effects of desipramine treatment alone and in combination with L-triiodothyronine on 6-sulphatoxymelatonin excretion in depressed patients.
Topics: Adult; Aged; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Melatonin; Middle Aged; Time Factors; Triiodothyronine | 1989 |
Plasma melatonin during desmethylimipramine treatment: evidence for changes in noradrenergic transmission.
Topics: Adult; Desipramine; Humans; Male; Melatonin; Norepinephrine; Synaptic Transmission | 1985 |
Desmethylimipramine treatment increases melatonin production in humans.
Topics: Adult; Animals; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Middle Aged; Pineal Gland; Rats; Receptors, Adrenergic, beta | 1986 |
Neuroendocrine and other studies of the mechanism of antidepressant action of desipramine.
Topics: Animals; Blood Pressure; Clonidine; Depression; Desipramine; Growth Hormone; Humans; Melatonin; Phenylephrine; Pupil; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Secretory Rate; Synaptic Transmission; Tyramine | 1986 |
Day-night differences in the response of the pineal gland to swimming stress.
Topics: Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Conditioning, Psychological; Desipramine; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Swimming | 1988 |
Effects of antidepressants on entrainment of circadian rhythms.
Topics: Animals; Body Temperature; Circadian Rhythm; Clomipramine; Corticosterone; Desipramine; Male; Melatonin; Rats; Rats, Inbred Strains | 1988 |
Patterns of melatonin rhythms in depression.
Topics: Adult; Circadian Rhythm; Depression; Depressive Disorder; Desipramine; Female; Humans; Isoproterenol; Male; Melatonin; Norepinephrine; Pineal Gland; Reference Values | 1986 |
Norepinephrine or isoproterenol stimulation of pineal N-acetyltransferase activity and melatonin content in the Syrian hamster is restricted to the second half of the daily dark phase.
Topics: Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Cricetinae; Darkness; Desipramine; Isoproterenol; Male; Melatonin; Mesocricetus; Norepinephrine; Pineal Gland; Sympathetic Nervous System | 1987 |
Rhythmic melatonin response of the Syrian hamster pineal gland to norepinephrine in vitro and in vivo.
Topics: Animals; Cricetinae; Desipramine; In Vitro Techniques; Light; Melatonin; Mesocricetus; Norepinephrine; Periodicity; Pineal Gland; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Nocturnal serum melatonin in major depressive disorder before and after desmethylimipramine treatment.
Topics: Adult; Circadian Rhythm; Depressive Disorder; Desipramine; Humans; Male; Melatonin | 1985 |
The effect of desipramine upon melatonin and cortisol secretion in depressed and normal subjects.
Topics: Adolescent; Adult; Depressive Disorder; Desipramine; Female; Humans; Hydrocortisone; Male; Melatonin; Phenylephrine; Pupil; Time Factors; Tyramine | 1985 |
Inhibition of the metabolism of H3-melatonin by phenothiazines.
Topics: Amphetamine; Animals; Antimetabolites; Body Temperature; Brain; Chlorpromazine; Depression, Chemical; Desipramine; Female; Imipramine; Liver; Melatonin; Phenobarbital; Phenothiazines; Promazine; Promethazine; Rats; Tritium | 1968 |
The effect of chronic antidepressant administration on beta-adrenoceptor function of the rat pineal.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antidepressive Agents; Desipramine; Electroshock; Isoproterenol; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Down-regulation at pineal beta-adrenoceptors in depressed patients treated with desipramine?
Topics: Animals; Depression; Desipramine; Humans; Melatonin; Pineal Gland; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Effect of treatment of rats with antidepressants on melatonin concentrations in the pineal gland and serum.
Topics: Animals; Antidepressive Agents; Darkness; Desipramine; Isoproterenol; Male; Melatonin; Nialamide; Pineal Gland; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stimulation, Chemical | 1982 |
Effect of psychotrophic drugs on [14C]tryptophan metabolism in cultured rat pineal gland.
Topics: Animals; Cells, Cultured; Chlorpromazine; Desipramine; Haloperidol; Male; Melatonin; Norepinephrine; Phenothiazines; Pineal Gland; Psychotropic Drugs; Rats; Serotonin; Tryptophan | 1983 |
An inverse correlation between serum levels of desmethylimipramine and melatonin-like immunoreactivity in DMI-responsive depressives.
Topics: Adolescent; Adult; Aged; Depression; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Middle Aged | 1981 |
A single injection of adrenergic agonists enhances pineal melatonin production in Turkish hamsters.
Topics: Animals; Circadian Rhythm; Cricetinae; Dark Adaptation; Desipramine; Injections, Subcutaneous; Isoproterenol; Light; Melatonin; Mesocricetus; Norepinephrine; Pineal Gland; Radioimmunoassay | 1993 |
Lack of association between thyroid and pineal responses to antidepressant treatment.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Male; Melatonin; Middle Aged; Pineal Gland; Psychophysiology; Thyroid Function Tests; Thyroid Gland; Thyroid Hormones | 1996 |
Influence of the antidepressants desipramine and fluoxetine on tryptophan-2,3-dioxygenase in the presence of exogenous melatonin.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Fluoxetine; Liver; Male; Melatonin; Rats; Rats, Wistar; Tryptophan Oxygenase | 1998 |
The toxicity of 6-hydroxydopamine on PC12 and P19 cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aurintricarboxylic Acid; Biological Transport; Bisbenzimidazole; Carrier Proteins; Cell Membrane; Desipramine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Dyes; Free Radical Scavengers; In Situ Nick-End Labeling; Melatonin; Membrane Glycoproteins; Membrane Transport Proteins; Necrosis; Nerve Tissue Proteins; Neurons; NG-Nitroarginine Methyl Ester; Oxidopamine; Parkinson Disease, Secondary; PC12 Cells; Rats; Sympatholytics; Tretinoin; Tritium | 1999 |
Antidepressant action of agomelatine (S 20098) in a transgenic mouse model.
Topics: Acetamides; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Desipramine; Disease Models, Animal; In Situ Hybridization; Male; Maze Learning; Melatonin; Mice; Mice, Transgenic; Receptors, Glucocorticoid; Swimming; Telemetry; Time Factors | 2005 |
Protection against cell death and sustained tyrosine hydroxylase phosphorylation in hydrogen peroxide- and MPP-treated human neuroblastoma cells with melatonin.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Blotting, Western; Cell Death; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Desipramine; Humans; Hydrogen Peroxide; Melatonin; Neuroblastoma; Phosphorylation; Tyrosine 3-Monooxygenase | 2009 |
Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells.
Topics: bcl-2-Associated X Protein; Caspase 3; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Desipramine; Drug Interactions; Humans; Melatonin; Methamphetamine; Microscopy, Fluorescence; Mitochondria; Neuroblastoma; Neuroprotective Agents; Signal Transduction | 2009 |
Ozone exposure of Flinders Sensitive Line rats is a rodent translational model of neurobiological oxidative stress with relevance for depression and antidepressant response.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Depressive Disorder, Major; Desipramine; Disease Models, Animal; Hippocampus; Male; Melatonin; Oxidative Stress; Ozone; Rats | 2015 |