desipramine and mazindol

desipramine has been researched along with mazindol in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.67)18.7374
1990's15 (50.00)18.2507
2000's6 (20.00)29.6817
2010's4 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goodman, MM; Kabalka, GW; Kung, HF; Kung, MP; Switzer, R1
Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD1
Adkins, S; Duval, RA; Foster, JD; Hauck-Newman, A; Kulkarni, SS; Lever, JR; Parnas, ML; Sakrikar, DS; Vaughan, RA1
Belardi, JK; Bray, JA; Burroughs, KD; Cohn, ST; Cosmi, SA; Deecher, DC; Gavrin, LK; Ho, DM; Johnston, GH; Koury, EJ; Leiter, J; Leventhal, L; Mahaney, PE; Mugford, CA; Platt, B; Rosenzweig-Lipson, SJ; Sabatucci, JP; Santilli, AA; Smith, VA; Stack, GP; Trybulski, EJ; Vu, TA; Ye, F; Zhang, Y1
Bray, J; Deecher, D; Johnston, G; Koury, E; Mahaney, PE; McComas, CC; Terefenko, EA; Trybulski, E; Vu, A; Zhang, P1
Bray, JA; Cohn, ST; Deecher, DC; Dooley, R; Goljer, I; Johnston, GH; Leiter, J; Mahaney, PE; Moore, WJ; Terefenko, EA; Trybulski, EJ; Vu, AT; Zhang, P1
Deecher, DC; Ho, DM; Kim, CY; Mahaney, PE; Manas, E; McConnell, O; Trybulski, EJ; Zhang, Y1
Bray, J; Deecher, D; Fensome, A; Harrison, J; Kim, C; Koury, E; Mahaney, PE; Mark, L; McComas, CC; Mugford, CA; Terefenko, EA; Trybulski, EJ; Vu, AT; Whiteside, GT; Zhang, P1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Burroughs, K; Cosmi, S; Deecher, DC; Ho, D; Johnston, G; Leiter, J; Mahaney, PE; Sabatucci, JP; Trybulski, E; Zhang, Y1
Adedoyin, A; Alfinito, PD; Bray, JA; Cosmi, S; Deecher, DC; Fensome, A; Harrison, J; Leventhal, L; Mann, C; McComas, CC; O'Neill, DJ; Spangler, TB; Sullivan, NR; Trybulski, EJ; Uveges, AJ; Whiteside, GT; Zhang, P1
Adedoyin, A; Bray, JA; Deecher, DC; Fensome, A; Goldberg, JA; Harrison, J; Leventhal, L; Mann, C; Mark, L; Nogle, L; O'Neill, DJ; Spangler, TB; Sullivan, NR; Terefenko, EA; Trybulski, EJ; Uveges, AJ; Vu, A; Whiteside, GT; Zhang, P1
De Souza, EB; Mitchell, WM; Pilotte, NS; Sharpe, LG1
Bienvenu, OJ; De Souza, EB; Goeders, NE1
Chilco, PJ; Donnan, GA; Kaczmarczyk, SJ; Kalnins, RM; Mendelsohn, FA; Paxinos, G; Woodhouse, DG1
Insel, TR; Winslow, JT1
Berger, P; Elsworth, JD; Reith, ME; Roth, RH; Tanen, D1
Sieber-Blum, M1
Chilco, PJ; Donnan, GA; Kaczmarczyk, SJ; Kalnins, RM; McKenzie, JS; Mendelsohn, FA1
Coyle, JT; Saltarelli, MD; Yamada, K1
Javitch, JA; Snyder, SH; Strittmatter, SM1
Cohen, G; Dembiec, D1
Dunn-Meynell, AA; Levin, BE1
Aoyama, T; Iga, T; Kotaki, H; Sawada, Y1
Patel, A1
Arregui, A; Hollingsworth, Z; Penney, JB; Young, AB1
Bentson, K; Figlewicz, DP; Ocrant, I1
Berman, R; Charney, DS; Delgado, PL; Heninger, GR; Krystal, JH; Miller, HL; Salomon, RM1
Dembiec-Cohen, D1
Levi, R; Smith, NC1

Trials

1 trial(s) available for desipramine and mazindol

ArticleYear
Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression.
    Archives of general psychiatry, 1996, Volume: 53, Issue:2

    Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Antidepressive Agents; Brain; Brain Chemistry; Depressive Disorder; Desipramine; Diphenhydramine; Dopamine; Fluoxetine; Humans; Mazindol; Methyltyrosines; Norepinephrine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sertraline

1996

Other Studies

29 other study(ies) available for desipramine and mazindol

ArticleYear
Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents.
    Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10

    Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tropanes

1994
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes

1999
Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter.
    The Journal of biological chemistry, 2007, Mar-23, Volume: 282, Issue:12

    Topics: Animals; Azides; Cocaine; Cyanogen Bromide; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epitopes; Humans; Iodine Radioisotopes; Methionine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Trypsin

2007
Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Animals; Cell Line; Cyclohexanols; Ethylamines; Female; Humans; Male; Mice; Models, Molecular; Molecular Structure; Norepinephrine; Pain; Rats; Structure-Activity Relationship; Symporters

2008
Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors.
    Bioorganic & medicinal chemistry letters, 2008, Dec-01, Volume: 18, Issue:23

    Topics: Benzimidazoles; Combinatorial Chemistry Techniques; Drug Design; Humans; Molecular Structure; Neurotransmitter Uptake Inhibitors; Norepinephrine; Stereoisomerism

2008
3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors.
    Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9

    Topics: Adrenergic Uptake Inhibitors; Animals; Chemistry, Pharmaceutical; Dogs; Dopamine Plasma Membrane Transport Proteins; Drug Design; Humans; Inhibitory Concentration 50; Ligands; Models, Chemical; Norepinephrine; Propanolamines; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship

2009
Discovery of a new series of monoamine reuptake inhibitors, the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ols.
    Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Cell Line; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Dogs; Dopamine Plasma Membrane Transport Proteins; Drug Discovery; Humans; Molecular Conformation; Norepinephrine; Propanols; Recombinant Proteins; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship

2009
1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors.
    Journal of medicinal chemistry, 2009, Sep-24, Volume: 52, Issue:18

    Topics: Administration, Oral; Animals; Behavior, Animal; Benzimidazoles; Biological Transport; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Hyperalgesia; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propanolamines; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Spinal Nerves; Structure-Activity Relationship; Substrate Specificity

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, May-01, Volume: 20, Issue:9

    Topics: Animals; Crystallography, X-Ray; Ethylamines; Humans; Molecular Conformation; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Structure-Activity Relationship; Thiophenes

2010
Discovery of novel selective norepinephrine reuptake inhibitors: 4-[3-aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231).
    Journal of medicinal chemistry, 2010, Jun-10, Volume: 53, Issue:11

    Topics: Animals; Cell Line; Cyclic S-Oxides; Drug Discovery; Female; Humans; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Structure-Activity Relationship; Thiadiazoles

2010
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
    Journal of medicinal chemistry, 2011, Oct-13, Volume: 54, Issue:19

    Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Benzothiazoles; Biological Availability; Cell Line; Chronic Pain; Cricetinae; Cyclic S-Oxides; Dogs; Humans; Inflammation; Injections, Intravenous; Male; Morpholines; Neuralgia; Norepinephrine Plasma Membrane Transport Proteins; Rats; Stereoisomerism; Thiadiazoles

2011
Withdrawal of repeated cocaine decreases autoradiographic [3H]mazindol-labelling of dopamine transporter in rat nucleus accumbens.
    European journal of pharmacology, 1991, Oct-02, Volume: 203, Issue:1

    Topics: Animals; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Densitometry; Desipramine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Substance Withdrawal Syndrome

1991
Chronic cocaine administration alters corticotropin-releasing factor receptors in the rat brain.
    Brain research, 1990, Oct-29, Volume: 531, Issue:1-2

    Topics: Animals; Autoradiography; Brain; Cerebral Ventricles; Cocaine; Corticotropin-Releasing Hormone; Desipramine; Hydroxydopamines; Male; Mazindol; Organ Specificity; Oxidopamine; Rats; Rats, Inbred F344; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurotransmitter; Reference Values; Substance-Related Disorders; Tritium

1990
Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography.
    The Journal of comparative neurology, 1991, Feb-15, Volume: 304, Issue:3

    Topics: Aged; Benztropine; Binding, Competitive; Biological Transport; Brain Chemistry; Brain Mapping; Caudate Nucleus; Citalopram; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Humans; Locus Coeruleus; Mazindol; Medulla Oblongata; Mianserin; Middle Aged; Norepinephrine; Piperazines; Pons; Substantia Nigra

1991
Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:1

    Topics: Animals; Body Temperature; Catecholamines; Citalopram; Clomipramine; Desipramine; Flumazenil; Mazindol; Motor Activity; Naltrexone; Nortriptyline; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stress, Psychological; Ultrasonics; Vocalization, Animal

1990
Complex interaction of cocaine with the dopamine uptake carrier.
    European journal of pharmacology, 1990, Feb-06, Volume: 176, Issue:2

    Topics: Animals; Cocaine; Corpus Striatum; Desipramine; In Vitro Techniques; Kinetics; Male; Mazindol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Vas Deferens

1990
Inhibition of the adrenergic phenotype in cultured neural crest cells by norepinephrine uptake inhibitors.
    Developmental biology, 1989, Volume: 136, Issue:2

    Topics: Adrenergic Fibers; Animals; Biological Transport; Chlorpromazine; Citalopram; Coturnix; Desipramine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Mazindol; Neural Crest; Neurotransmitter Uptake Inhibitors; Norepinephrine; Tyrosine 3-Monooxygenase

1989
Catecholamine uptake sites in mouse brain: distribution determined by quantitative [3H]mazindol autoradiography.
    Brain research, 1989, Dec-11, Volume: 504, Issue:1

    Topics: Animals; Binding, Competitive; Brain; Corpus Striatum; Desipramine; Indoles; Locus Coeruleus; Mazindol; Mice; Mice, Inbred C57BL; Neurotoxins; Receptors, Adrenergic; Receptors, Dopamine

1989
Specificity of the activation of [3H]hemicholinium-3 binding by phospholipase A2.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3

    Topics: Animals; Brain; Choline; Desipramine; Hemicholinium 3; Male; Mazindol; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Rats; Rats, Inbred Strains; Synaptic Membranes; Tritium

1989
Differential visualization of dopamine and norepinephrine uptake sites in rat brain using [3H]mazindol autoradiography.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:6

    Topics: Animals; Autoradiography; Brain; Corpus Striatum; Desipramine; Dopamine; Indoles; Male; Mazindol; Norepinephrine; Rats; Rats, Inbred Strains; Tritium

1985
Potassium-induced release of [3H]catecholamine from brain: effects of pre-exposure to catecholamine uptake inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Acetophenones; Animals; Brain Chemistry; Catecholamines; Cocaine; Corpus Striatum; Desipramine; Dopamine; Drug Interactions; Imidazoles; In Vitro Techniques; Male; Mazindol; Nomifensine; Norepinephrine; Occipital Lobe; Potassium; Rats

1981
Selective sprouting of injured dopaminergic neurons induced by embryonic brain grafts.
    Experimental neurology, 1993, Volume: 124, Issue:2

    Topics: Animals; Autoradiography; Brain Tissue Transplantation; Carrier Proteins; Cerebral Cortex; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Dopamine Plasma Membrane Transport Proteins; Fetal Tissue Transplantation; Immunohistochemistry; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Fibers; Nerve Tissue Proteins; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Symporters; Tritium; Tyrosine 3-Monooxygenase

1993
Stereospecific distribution of methylphenidate enantiomers in rat brain: specific binding to dopamine reuptake sites.
    Pharmaceutical research, 1994, Volume: 11, Issue:3

    Topics: Animals; Brain; Desipramine; Injections, Intravenous; Male; Mazindol; Methylphenidate; Neurotransmitter Uptake Inhibitors; Rats; Rats, Wistar; Receptors, Dopamine; Stereoisomerism

1994
Characterization of [125I]RTI-55 binding to dog caudate dopamine transporter.
    Neuroreport, 1993, Nov-18, Volume: 5, Issue:2

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cell Membrane; Cholic Acids; Citalopram; Cocaine; Desipramine; Dogs; Dopamine Plasma Membrane Transport Proteins; Filtration; Iodine Radioisotopes; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Solubility

1993
Autoradiographic evidence for increased dopamine uptake sites in striatum of hypoxic mice.
    Neuroscience letters, 1994, Feb-14, Volume: 167, Issue:1-2

    Topics: Animals; Autoradiography; Benzamides; Benzazepines; Binding Sites; Corpus Striatum; Desipramine; Dopamine; Dopamine D2 Receptor Antagonists; Hypoxia; Male; Mazindol; Mice; Mice, Inbred BALB C; Receptors, Dopamine D1; Receptors, Dopamine D2; Time Factors

1994
The effect of insulin on norepinephrine uptake by PC12 cells.
    Brain research bulletin, 1993, Volume: 32, Issue:4

    Topics: Animals; Binding Sites; Biological Transport; Cell Membrane; Desipramine; Dose-Response Relationship, Drug; Hippocampus; Hypothalamus; In Vitro Techniques; Insulin; Insulin-Like Growth Factor I; Kinetics; Male; Mazindol; Norepinephrine; PC12 Cells; Rats; Rats, Wistar

1993
Mazindol, nomifensine and desmethylimipramine inhibit potassium-induced release of dopamine: effect of stimulus strength.
    Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:6-7

    Topics: Adrenergic Uptake Inhibitors; Animals; Corpus Striatum; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mazindol; Nomifensine; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley

1998
LLC-PK(1) cells stably expressing the human norepinephrine transporter: A functional model of carrier-mediated norepinephrine release in protracted myocardial ischemia.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Biological Transport, Active; Desipramine; Drug Interactions; Gramicidin; Humans; Imidazoline Receptors; LLC-PK1 Cells; Mazindol; Models, Biological; Myocardial Ischemia; Nigericin; Norepinephrine; Receptors, Drug; Sodium; Swine; Time Factors

1999