desipramine and ly2603618

desipramine has been researched along with ly2603618 in 1 studies

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chandler, J; Decker, R; Hynes, SM; Mitchell, M; Ott, J; Wickremsinhe, E; Zhang, W	1

Trials

1 trial(s) available for desipramine and ly2603618

Article	Year
Evaluation of the likelihood of a selective CHK1 inhibitor (LY2603618) to inhibit CYP2D6 with desipramine as a probe substrate in cancer patients. Biopharmaceutics & drug disposition, 2015, Volume: 36, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Area Under Curve; Checkpoint Kinase 1; Computer Simulation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Desipramine; Drug Interactions; Female; Humans; Infusions, Intravenous; Least-Squares Analysis; Male; Middle Aged; Neoplasms; Phenylurea Compounds; Protein Kinases; Pyrazines; Young Adult	2015

Article

Year

Evaluation of the likelihood of a selective CHK1 inhibitor (LY2603618) to inhibit CYP2D6 with desipramine as a probe substrate in cancer patients.

Biopharmaceutics & drug disposition, 2015, Volume: 36, Issue:1

Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Area Under Curve; Checkpoint Kinase 1; Computer Simulation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Desipramine; Drug Interactions; Female; Humans; Infusions, Intravenous; Least-Squares Analysis; Male; Middle Aged; Neoplasms; Phenylurea Compounds; Protein Kinases; Pyrazines; Young Adult

2015