desipramine and lofepramine

desipramine has been researched along with lofepramine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's5 (33.33)18.2507
2000's3 (20.00)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Badawy, AA; Dacey, A; Morgan, CJ; Stoppard, T1
Carrón, R; Delpón, E; Pérez-Vizcaino, F; Tamargo, J1
Baldwin, DS; Lack, SJ; Montgomery, SA1
Henry, JA; Virgili, P1
Leonard, BE1
Leonard, BE; O'Connor, WT1
Edström, A; Ekström, P; Kanje, M1
Arlock, P1
Elm, T; Hansen, EL1
Kelly, JP; Leonard, BE1
Darcy, P; Henry, JA; Kelly, JP; Leonard, BE1

Reviews

1 review(s) available for desipramine and lofepramine

ArticleYear
A comparison of the pharmacological properties of the novel tricyclic antidepressant lofepramine with its major metabolite, desipramine: a review.
    International clinical psychopharmacology, 1987, Volume: 2, Issue:4

    Topics: Animals; Cardiovascular System; Chemical Phenomena; Chemistry; Depression; Desipramine; Dibenzazepines; Disease Models, Animal; Humans; Lofepramine; Nervous System; Neurotransmitter Agents; Parasympatholytics

1987

Other Studies

14 other study(ies) available for desipramine and lofepramine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effects of lofepramine and desmethylimipramine on tryptophan metabolism and disposition in the rat.
    Biochemical pharmacology, 1991, Jul-25, Volume: 42, Issue:4

    Topics: Animals; Desipramine; Drug Administration Schedule; Hemin; Hydrocortisone; Indoleamine-Pyrrole 2,3,-Dioxygenase; Liver; Lofepramine; Male; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase

1991
Effects of (S)-nafenodone, a new antidepressant, in isolated guinea-pig atrial and ventricular muscle fibres.
    European journal of pharmacology, 1991, Jun-18, Volume: 199, Issue:1

    Topics: Action Potentials; Animals; Antidepressive Agents; Calcium; Desipramine; Female; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Imipramine; In Vitro Techniques; Isoproterenol; Lofepramine; Male; Myocardial Contraction; Naphthalenes; Papillary Muscles; Refractory Period, Electrophysiological

1991
Lofepramine, desipramine and abnormal tests of liver function: a case report.
    International clinical psychopharmacology, 1990, Volume: 5, Issue:3

    Topics: Depression; Desipramine; Humans; Liver Function Tests; Lofepramine; Male; Middle Aged

1990
Determination of lofepramine and desipramine using high-performance liquid chromatography and electrochemical detection.
    Journal of chromatography, 1989, Nov-10, Volume: 496, Issue:1

    Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Desipramine; Dibenzazepines; Electrochemistry; Humans; Lofepramine

1989
Behavioural and neuropharmacological properties of the dibenzazepines, desipramine and lofepramine: studies on the olfactory bulbectomized rat model of depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:1

    Topics: Animals; Arousal; Avoidance Learning; Behavior, Animal; Clonidine; Depressive Disorder; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Exploratory Behavior; Lofepramine; Male; Motor Activity; Olfactory Bulb; Rats; Rats, Inbred Strains; Smell

1988
Effects of phenothiazines and dibenzazepines on axonal transport and microtubule assembly in vitro.
    Acta physiologica Scandinavica, 1982, Volume: 116, Issue:2

    Topics: Adenosine Triphosphate; Amitriptyline; Animals; Axonal Transport; Chlorpromazine; Desipramine; Dibenzazepines; Lofepramine; Microtubules; Phenothiazines; Phosphocreatine; Rana pipiens; Rana temporaria; Sciatic Nerve; Thioridazine; Trifluoperazine

1982
Actions of lofepramine, a new tricyclic antidepressant, and desipramine on electrophysiological and mechanical parameters of guinea pig atrial and papillary muscles.
    Acta pharmacologica et toxicologica, 1981, Volume: 49, Issue:4

    Topics: Action Potentials; Animals; Desipramine; Dibenzazepines; Electrophysiology; Guinea Pigs; Heart; Heart Atria; Heart Conduction System; In Vitro Techniques; Lofepramine; Myocardial Contraction; Papillary Muscles

1981
Simultaneous determination of lofepramine and desipramine by a high-performance liquid chromatographic method used for therapeutic drug monitoring.
    Journal of chromatography. B, Biomedical applications, 1995, Mar-24, Volume: 665, Issue:2

    Topics: Chromatography, High Pressure Liquid; Desipramine; Drug Monitoring; Humans; Kinetics; Lofepramine; Quality Control; Reference Values; Sensitivity and Specificity

1995
An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2

    Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Imipramine; Lofepramine; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Swimming

1999
The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis.
    Toxicology letters, 2002, Mar-10, Volume: 128, Issue:1-3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; beta-Cyclodextrins; Cell Membrane; Cyclodextrins; Desipramine; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Inhibitory Concentration 50; Lofepramine; Statistics, Nonparametric; Swimming; Tetrahymena pyriformis; Video Recording

2002