desipramine and ketamine

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate

Topics: Animals; Anti-Inflammatory Agents; Chlorpromazine; Desipramine; Diazepam; Female; In Vitro Techniques; Ketamine; Muscle, Smooth; Papaverine; Pregnancy; Pregnancy, Animal; Rats; Uterine Contraction

Topics: Action Potentials; Animals; Anticonvulsants; Cerebral Cortex; Convulsants; Corpus Callosum; Desipramine; Epilepsy; Female; Ion Channels; Ketamine; Magnesium; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Stimulation, Chemical

Topics: Animals; Bupranolol; Corticosterone; Desipramine; Ferrets; In Vitro Techniques; Ketamine; Myocardial Contraction; Papillary Muscles; Phentolamine; Reserpine; Stimulation, Chemical

Topics: Animals; Desipramine; Drug Synergism; Ketamine; Rats

Topics: Animals; Anticonvulsants; Aspartic Acid; Brain; Calcium; Desipramine; Dibenzocycloheptenes; Dizocilpine Maleate; gamma-Aminobutyric Acid; Ketamine; Kynurenine; Membranes; N-Methylaspartate; Piperazines; Pyrrolidinones; Radioligand Assay; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine

Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Aspartic Acid; Cerebral Ventricles; Desipramine; Electrocardiography; European Union; Female; Glutamic Acid; Injections, Intraventricular; Ketamine; Male; Ouabain; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, N-Methyl-D-Aspartate

Topics: Adrenal Medulla; Adrenergic Uptake Inhibitors; Analgesics; Anesthetics, Local; Animals; Binding Sites; Biological Transport; Cattle; Cell Membrane; Cells, Cultured; Cocaine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Hallucinogens; Ketamine; Norepinephrine; Phencyclidine

Topics: Adrenal Medulla; Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cattle; Cell Membrane; Cells, Cultured; Desipramine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Indoles; Ketamine; Maleimides; Neuromuscular Blocking Agents; Neuromuscular Nondepolarizing Agents; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Pancuronium; Protein Kinase C; Symporters

Topics: Adrenal Medulla; Adrenergic Uptake Inhibitors; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Carrier Proteins; Cattle; Cell Membrane; Cells, Cultured; Desipramine; Diazepam; Drug Administration Schedule; Ketamine; Kinetics; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propofol; RNA, Messenger; Symporters; Thiamylal; Tritium

Topics: Adrenergic Uptake Inhibitors; Animals; Calcium Channel Blockers; Catecholamines; Cats; Coronary Artery Disease; Desipramine; Epinephrine; Excitatory Amino Acid Antagonists; Female; Heart; Ketamine; Male; Myocardial Ischemia; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; omega-Conotoxin GVIA; Presynaptic Terminals; Sympathetic Fibers, Postganglionic; Symporters; Synaptic Transmission

Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Apomorphine; Cerebral Cortex; Depression; Desipramine; Dopamine Agonists; Drug Tolerance; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hindlimb Suspension; Ketamine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, beta; Swimming

Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hindlimb Suspension; Ketamine; Male; Mice; Motor Activity; Psychomotor Performance; Solvents; Swimming; Toluene

Topics: Anesthetics, Dissociative; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Intensive Care Units; Ketamine

Topics: Animals; Antidepressive Agents, Tricyclic; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Desipramine; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Ketamine; Male; Munc18 Proteins; Nerve Tissue Proteins; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; SNARE Proteins; Swimming; Synaptosomal-Associated Protein 25; Synaptosomes; Synaptotagmin I; Time Factors

Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Apoptosis; Autoreceptors; Blotting, Western; Brain; CASP8 and FADD-Like Apoptosis Regulating Protein; Cerebral Cortex; Clorgyline; Desipramine; Electroshock; Excitatory Amino Acid Antagonists; Fas-Associated Death Domain Protein; Fluoxetine; Idazoxan; Indans; Ketamine; Male; Mianserin; Mirtazapine; Monoamine Oxidase Inhibitors; Norepinephrine Plasma Membrane Transport Proteins; Phenelzine; Phosphoproteins; Phosphorylation; Rats; RNA-Binding Proteins; Thiazoles

Topics: Animals; Antidepressive Agents; Anxiety; Depression; Desipramine; Dopamine; Elevated Plus Maze Test; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Genes, fos; Ketamine; Long-Term Potentiation; Male; Motivation; Open Field Test; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Psychological; Swimming; Tyrosine 3-Monooxygenase; Ventral Tegmental Area