desipramine and iprindole

desipramine has been researched along with iprindole in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199035 (87.50)18.7374
1990's3 (7.50)18.2507
2000's1 (2.50)29.6817
2010's1 (2.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Cohen, D; Weinstock, M1
Sulser, F; Vetulani, J1
Dingell, JV; Stawarz, RJ; Sulser, F; Vetulani, J1
Banerjee, SP; Chanda, SK; Kung, LS; Riggi, SJ1
Harden, TK; Molinoff, PB; Sporn, JR; Wolfe, BB1
Freeman, JJ; Sulser, F1
Daivis, JM; Rosloff, BN1
Kjellberg, B; Randrup, A1
Davis, JM; Rosloff, BN2
Bevan, P; Bradshaw, CM; Szabadi, E1
Erez, M; Manoach, M; Varon, D; Wozner, D1
Bönisch, H; Coppeneur, D; Lingen, B; Martiny-Baron, G; Paulus, G1
Cooper, MM; Day, JS; Sethy, VH1
Hancock, AA; Marsh, CL1
Moyer, JA; Sigg, EB; Silver, PJ1
Handley, SL; Singh, L1
Chuang, DM; Costa, E; Nakaki, T; Roth, BL1
Barth, N1
Barth, N; Muscholl, E1
Brezinova, V; Dunleavy, DL; Maclean, AW; Oswald, I; Tinker, M1
Mattila, MJ; Saarnivaara, L1
Huang, Y; Maas, JW1
Reilly, MA; Sigg, EB1
Crews, FT; Smith, CB2
García-Sevilla, JA; Hollingsworth, PJ; Smnith, CB1
Gillespie, DD; Janowsky, A; Steranka, LR; Sulser, F1
Scuvée-Moreau, JJ; Svensson, TH1
Aghajanian, GK; Gallager, DW; Menkes, DB1
Aghajanian, GK; Davis, M; Gallager, DW; Kehne, JH; Menkes, DB1
Phillis, JW1
Montgomery, T; Towell, A; Willner, P1
Carter, RB; Leander, JD1
Dupont, A; Merand, Y; Savard, P1
Sugrue, MF1
Aspeslet, LJ; Baker, GB; Coutts, RT; Torok-Both, GA1

Reviews

1 review(s) available for desipramine and iprindole

ArticleYear
Noradrenergic function and depression, too much or too little?
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1980, Volume: 7, Issue:3

    Topics: Amphetamine; Bipolar Disorder; Brain; Brain Chemistry; Desipramine; Electroconvulsive Therapy; Humans; Imipramine; Iprindole; Methoxyhydroxyphenylglycol; Norepinephrine; S-Adenosylmethionine; Tyrosine 3-Monooxygenase

1980

Trials

1 trial(s) available for desipramine and iprindole

ArticleYear
Changes during weeks in effects of tricyclic drugs on the human sleeping brain.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 120, Issue:559

    Topics: Adult; Antidepressive Agents; Brain Chemistry; Desipramine; Dibenzazepines; Dibenzoxepins; Electroencephalography; Humans; Imipramine; Iprindole; Male; Motor Activity; Placebos; Sleep; Sleep, REM; Time Factors

1972

Other Studies

38 other study(ies) available for desipramine and iprindole

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Tricyclic antidepressant drugs as antagonists of muscarinic receptors in sympathetic ganglia.
    European journal of pharmacology, 1976, Volume: 40, Issue:2

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Antidepressive Agents, Tricyclic; Cats; Clomipramine; Desipramine; Dimethylphenylpiperazinium Iodide; Ganglia, Autonomic; Ganglia, Spinal; Imipramine; Iprindole; Nictitating Membrane; Norepinephrine; Receptors, Cholinergic; Receptors, Muscarinic; Serotonin; Viloxazine

1976
Action of various antidepressant treatments reduces reactivity of noradrenergic cyclic AMP-generating system in limbic forebrain.
    Nature, 1975, Oct-09, Volume: 257, Issue:5526

    Topics: Animals; Cyclic AMP; Depression, Chemical; Desipramine; Electroconvulsive Therapy; Indoles; Iprindole; Limbic System; Male; Norepinephrine; Rats; Receptors, Adrenergic; Reserpine; Time Factors

1975
A possible common mechanism of action of antidepressant treatments: reduction in the sensitivity of the noradrenergic cyclic AMP gererating system in the rat limbic forebrain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 293, Issue:2

    Topics: Animals; Antidepressive Agents, Tricyclic; Cyclic AMP; Desipramine; Electroshock; Iprindole; Limbic System; Male; Norepinephrine; Rats

1976
Development of beta-adrenergic receptor subsensitivity by antidepressants.
    Nature, 1977, Aug-04, Volume: 268, Issue:5619

    Topics: Alprenolol; Animals; Antidepressive Agents, Tricyclic; Brain; Desipramine; Doxepin; Iprindole; Kinetics; Male; Microsomes; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta

1977
Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Desipramine; Guanosine Triphosphate; Iprindole; Male; Pargyline; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta

1978
The role of p-hydroxylation of amphetamine in its peripheral mode of action.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:1

    Topics: Amphetamine; Animals; Blood Pressure; Depression, Chemical; Desipramine; Dextroamphetamine; Heart; Humans; Hydroxylation; Iprindole; Male; Myocardium; Norepinephrine; Rats; Time Factors

1975
Decrease in brain NE turnover after chronic DMI treatment; no effect with iprindole.
    Psychopharmacology, 1978, Apr-11, Volume: 56, Issue:3

    Topics: Animals; Brain; Desipramine; Dopamine; Indoles; Iprindole; Norepinephrine; Rats; Time Factors; Tyrosine

1978
Behavioral effects of thymoleptics in vervet monkeys (Cercopithecus aethiops).
    Psychopharmacologia, 1975, Sep-17, Volume: 43, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chlorocebus aethiops; Clomipramine; Desipramine; Female; Haplorhini; Iprindole; Male; Motor Activity; Posture

1975
Lack of effect of acute and chronic treatment with tricyclic antidepressants on rat brain choline acetyltransferase.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:4

    Topics: Acetyltransferases; Animals; Antidepressive Agents, Tricyclic; Brain; Choline O-Acetyltransferase; Desipramine; Iprindole; Male; Rats; Time Factors

1976
Tricyclic antidepressants and monoamines: the relationship between uptake blockade and potentiation of neuronal responses.
    British journal of pharmacology, 1975, Volume: 53, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Biogenic Amines; Depression, Chemical; Desipramine; In Vitro Techniques; Iprindole; Mescaline; Neurons; Rats

1975
Ventricular defibrillating properties of catecholamine uptake inhibitors.
    Life sciences, 1992, Volume: 51, Issue:17

    Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Cats; Cocaine; Desipramine; Electrocardiography; Female; Iprindole; Male; Maprotiline; Mianserin; Ventricular Fibrillation

1992
Molecular aspects of the neuronal noradrenaline transporter.
    Journal of neural transmission. Supplementum, 1991, Volume: 34

    Topics: Adrenal Medulla; Animals; Carrier Proteins; Cattle; Cell Membrane; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Desipramine; Iprindole; Maprotiline; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Oocytes; PC12 Cells; Poly A; RNA; RNA, Messenger; Symporters; Xenopus laevis

1991
Dose-dependent down-regulation of beta-adrenergic receptors after chronic intravenous infusion of antidepressants.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:5

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cerebral Cortex; Cyclopentanes; Desipramine; Dose-Response Relationship, Drug; Female; Imipramine; Infusions, Intravenous; Iprindole; Kinetics; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values; Zimeldine

1988
Agonist interactions with beta-adrenergic receptors following chronic administration of desipramine or the atypical antidepressants, iprindole and mianserin.
    Journal of receptor research, 1985, Volume: 5, Issue:5-6

    Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Cerebral Cortex; Desipramine; Dibenzazepines; Indoles; Iprindole; Kinetics; Male; Mianserin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Subcellular Fractions

1985
Antidepressants and protein kinases: desipramine treatment affects pineal gland cAMP-dependent protein kinase activity.
    European journal of pharmacology, 1986, Feb-11, Volume: 121, Issue:1

    Topics: Animals; Antidepressive Agents; Desipramine; Fluoxetine; Iprindole; Isoproterenol; Male; Pineal Gland; Protein Kinases; Rats; Rats, Inbred Strains; Zimeldine

1986
Chronic antidepressant treatment reduces central beta-adrenoceptor sensitivity in a behavioural test.
    European journal of pharmacology, 1986, Aug-07, Volume: 127, Issue:1-2

    Topics: 5-Hydroxytryptophan; Albuterol; Animals; Antidepressive Agents; Behavior, Animal; Desipramine; Dobutamine; Drug Resistance; Drug Synergism; Iprindole; Male; Mice; Prenalterol; Receptors, Adrenergic, beta

1986
5-Hydroxytryptamine uptake and imipramine binding sites in neurotumor NCB-20 cells.
    Journal of neurochemistry, 1985, Volume: 45, Issue:3

    Topics: Animals; Binding Sites; Brain; Clomipramine; Cricetinae; Cricetulus; Desipramine; Fluoxetine; Hybrid Cells; Imipramine; Iprindole; Kinetics; Mianserin; Neuroblastoma; Opipramol; Rats; Serotonin

1985
Proceedings: Arrhythmias evoked by infusion of tricyclic antidepressants and noradrenaline on isolated rabbit hearts.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Antidepressive Agents; Arrhythmias, Cardiac; Desipramine; Dose-Response Relationship, Drug; Doxepin; Heart Conduction System; In Vitro Techniques; Iprindole; Norepinephrine; Propranolol; Rabbits; Time Factors

1974
The effects of the tricyclic antidepressants desipramine, doxepin and iprindole on the isolated perfused rabbit heart.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 284, Issue:3

    Topics: Animals; Antidepressive Agents; Arrhythmias, Cardiac; Atropine; Autonomic Fibers, Postganglionic; Cocaine; Desipramine; Doxepin; Drug Antagonism; Electric Stimulation; Female; Heart; Heart Rate; Iprindole; Male; Perfusion; Propranolol; Quinidine; Rabbits; Sympathetic Nervous System; Time Factors

1974
Effect of iprindole on norepinephrine turnover and transport.
    Psychopharmacologia, 1974, Volume: 40, Issue:1

    Topics: Animals; Biogenic Amines; Biological Transport; Brain; Depression, Chemical; Desipramine; In Vitro Techniques; Indoles; Iprindole; Male; Methyltyrosines; Norepinephrine; Rats; Synaptosomes; Time Factors

1974
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
    Psychopharmacologia, 1974, Feb-27, Volume: 35, Issue:3

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors

1974
Suppression of histamine-induced adrenocorticotropic hormone release by antihistamines and antidepressants.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3

    Topics: Adrenocorticotropic Hormone; Amitriptyline; Animals; Antidepressive Agents; Desipramine; Diazepam; Doxepin; Histamine; Histamine H1 Antagonists; Imipramine; Iprindole; Male; Mianserin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Histamine; Stimulation, Chemical

1982
Potentiation of responses to adrenergic nerve stimulation in isolated rat atria during chronic tricyclic antidepressant administration.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Electric Stimulation; Heart Atria; In Vitro Techniques; Iprindole; Male; Muscles; Nerve Endings; Norepinephrine; Nortriptyline; Rats; Receptors, Adrenergic, alpha; Stimulation, Chemical; Sympathetic Nervous System

1980
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
    European journal of pharmacology, 1981, Sep-24, Volume: 74, Issue:4

    Topics: Adult; Amitriptyline; Antidepressive Agents; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Desipramine; Humans; In Vitro Techniques; Iprindole; Kinetics; Male; Mianserin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine

1981
Role of neuronal signal input in the down-regulation of central noradrenergic receptor function by antidepressant drugs.
    Journal of neurochemistry, 1982, Volume: 39, Issue:1

    Topics: Animals; Cyclic AMP; Desipramine; Frontal Lobe; Indoles; Iprindole; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic

1982
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
    Journal of neural transmission, 1982, Volume: 54, Issue:1-2

    Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine

1982
Chronic antidepressant treatment enhances agonist affinity of brain alpha 1-adrenoceptors.
    European journal of pharmacology, 1983, Jan-28, Volume: 87, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Binding, Competitive; Brain; Desipramine; Iprindole; Kinetics; Male; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thalamus

1983
Functional supersensitivity of CNS alpha 1-adrenoceptors following chronic antidepressant treatment.
    Life sciences, 1983, Jul-11, Volume: 33, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Binding Sites; Desipramine; Hydroxydopamines; Iprindole; Male; Norepinephrine; Oxidopamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex, Acoustic

1983
Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants.
    British journal of pharmacology, 1984, Volume: 83, Issue:2

    Topics: Action Potentials; Adenosine; Animals; Antidepressive Agents, Tricyclic; Caffeine; Cerebral Cortex; Clomipramine; Desipramine; Drug Synergism; Iprindole; Male; Neurons; Nortriptyline; Rats; Rats, Inbred Strains

1984
Changes in amphetamine-induced anorexia and stereotypy during chronic treatment with antidepressant drugs.
    European journal of pharmacology, 1984, Mar-02, Volume: 98, Issue:3-4

    Topics: Animals; Anorexia; Antidepressive Agents, Tricyclic; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Humans; Iprindole; Male; Mianserin; Rats; Stereotyped Behavior; Structure-Activity Relationship; Time Factors

1984
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists

1984
3H-mepyramine binding in various regions of rat brain following chronic treatment with different classes of antidepressant drugs.
    Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:4-6

    Topics: Aminopyridines; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Female; Iprindole; Nomifensine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1

1982
Effects of acutely and chronically administered antidepressants on the clonidine-induced decrease in rat brain 3-methoxy-4-hydroxyphenylethylene-glycol sulphate content.
    Life sciences, 1981, Jan-26, Volume: 28, Issue:4

    Topics: Animals; Antidepressive Agents; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Desipramine; Fluoxetine; Glycols; Iprindole; Male; Methoxyhydroxyphenylglycol; Mianserin; Rats

1981
The effects of antidepressants on the retention and metabolism of [3H]-norepinephrine in rat brain slices.
    Neuropharmacology, 1981, Volume: 20, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cocaine; Deamination; Desipramine; Dose-Response Relationship, Drug; In Vitro Techniques; Iprindole; Male; Norepinephrine; Nortriptyline; Protriptyline; Rats; Reserpine; Tritium

1981
The effects of desipramine and iprindole on levels of enantiomers of fluoxetine in rat brain and urine.
    Chirality, 1994, Volume: 6, Issue:2

    Topics: Animals; Brain; Chromatography, Gas; Desipramine; Fluoxetine; Iprindole; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism

1994