desipramine has been researched along with hexobarbital in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (73.68) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Lehmann, K; Schmidt, J | 1 |
| Daniel, W; Netter, KJ | 1 |
| Böke-Kuhn, K; Knappen, F | 1 |
| Conney, AH; Kappas, A | 1 |
| Orrenius, S; Schenkman, JB; von Bahr, C; Wilson, BJ | 1 |
| O'Malley, K; Sawyer, PR; Stevenson, IH | 1 |
| Orrenius, S; Schenkman, JB; von Bahr, C | 1 |
| Glaumann, H; Hietanen, E; von Bahr, C | 1 |
| Lal, H; Shah, HC | 1 |
| Kuntzman, R; Lemberger, L; Sernatinger, E | 1 |
| Kakemi, K; Kimura, T; Konishi, R; Sezaki, H | 1 |
| Eble, JN; Shriver, KL; Trepanier, DL | 1 |
| Bass, AD; Dingell, JV | 1 |
| Shillito, EE | 1 |
| BUECH, O; KUNZ, HA; MORPURGO, C; STENGER, EG; THEOBALD, W; WILHELMI, G | 1 |
2 review(s) available for desipramine and hexobarbital
| Article | Year |
|---|---|
Interindividual differences in the metabolism of xenobiotics.
Topics: Aflatoxin B1; Aflatoxins; Antipyrine; Benzopyrenes; Biotransformation; Carcinogens; Coumarins; Desipramine; Diet; Dihydroxydihydrobenzopyrenes; Hexobarbital; Humans; Liver; Microsomes, Liver; Pharmaceutical Preparations; Smoking; Steroids; Zoxazolamine | 1985 |
On the significance of drug-induced spectral changes in liver microsomes.
Topics: Alkaloids; Amphetamine; Aniline Compounds; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Hydroxylation; Microsomes, Liver; NADP; Nortriptyline; Oxidoreductases; Phenacetin; Rats; Spectrum Analysis; Testosterone; Tryptophan | 1972 |
17 other study(ies) available for desipramine and hexobarbital
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
[Effect of psychotropic drugs on somatosensory evoked cortical potentials].
Topics: Animals; Anti-Anxiety Agents; Desipramine; Diazepam; Evoked Potentials; Female; Haloperidol; Hexobarbital; Medazepam; Piperidines; Rats; Somatosensory Cortex | 1979 |
Alteration of cytochrome P-450 by prolonged administration of imipramine and/or lithium to rats.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Hexobarbital; Imipramine; Isoenzymes; Lithium; Liver; Male; Metyrapone; Rats; Rats, Inbred Strains | 1990 |
Interactions of brotizolam and diazepam with some psychotropic drugs on motor performance in mice.
Topics: Animals; Azepines; Desipramine; Diazepam; Drug Interactions; Ethanol; Female; Hexobarbital; Hypnotics and Sedatives; Mice; Psychomotor Performance; Psychotropic Drugs; Reflex; Time Factors | 1986 |
Proceedings: Effect of tricyclic antidepressants on drug metabolism.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Hexobarbital; Humans; Imipramine; Liver; Male; Nortriptyline; Rats | 1972 |
Effect of phenobarbital and 3,4-benzpyrene treatment of rats on the microsomal binding and hydroxylation of nortriptyline and desmethyl-imipramine: evidence for qualitative changes in cytochrome P-450-ligand interaction following phenobarbital pretreatmen
Topics: Animals; Benzopyrenes; Binding Sites; Chromatography, Gas; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Ligands; Male; Microsomes, Liver; Mixed Function Oxygenases; Nortriptyline; Phenobarbital; Protein Binding; Rats; Receptors, Drug; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1972 |
Oxidation and glucuronidation of certain drugs in various subcellular fractions of rat liver: binding of desmethylimipramine and hexobarbital to cytochrome P-450 and oxidation and glucuronidation of desmethylimipramine, aminopyrine, p-nitrophenol and 1-na
Topics: Aminopyrine; Animals; Cell Membrane; Cytochromes; Desipramine; Glucuronates; Golgi Apparatus; Hexobarbital; Hydroxylation; Liver; Male; Microsomes; Naphthalenes; Naphthols; Nitrophenols; Oxidation-Reduction; Rats; Spectrophotometry; Subcellular Fractions; Time Factors; Tritium | 1972 |
The potentiation of barbiturates by desipramine in the mouse: mechanism of action.
Topics: Animals; Barbiturates; Body Temperature; Brain Chemistry; Carbon Isotopes; Desipramine; Drug Synergism; Hexobarbital; Male; Mice; Pentobarbital; Time Factors; Urea | 1971 |
Effect of desmethylimipramine, iprindole and DL-erythro-alpha-(3,4-dichlorophenyl)-beta-(t-butyl amino) propanol HC1 on the metabolism of amphetamine.
Topics: 1-Propanol; Amines; Amino Alcohols; Amphetamine; Animals; Antidepressive Agents; Brain; Butylamines; Desipramine; Drug Synergism; Heart; Hexobarbital; Indoles; Kinetics; Male; Muscles; Myocardium; Norepinephrine; Paralysis; Rats; Sleep; Tritium; Zoxazolamine | 1970 |
Inhibitory mechanism of imipramine on barbiturate metabolism in rat liver.
Topics: Animals; Barbiturates; Depression, Chemical; Desipramine; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Rats; Secobarbital; Thiopental | 1971 |
Aryl-substituted triazines with antidepressant activity.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Synergism; Electroshock; Hexobarbital; Imipramine; Mice; Reserpine; Sleep; Triazines | 1969 |
Inhibition of the hepatic metabolism of amphetamine by desipramine.
Topics: Aminopyrine; Amphetamine; Animals; Desipramine; Hexobarbital; In Vitro Techniques; Liver; Male; Perfusion; Rats; Tritium | 1969 |
A method for recording the effect of drugs on the activity of small mammals over long periods of time.
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Desipramine; Hexobarbital; Hypnotics and Sedatives; Imipramine; Iproniazid; Meprobamate; Mice; Reserpine | 1966 |
[COMPARATIVE PHARMACOLOGICAL INVESTIGATIONS WITH TOFRANIL, PERTOFRAN AND INSIDON].
Topics: Acetylcholine; Amphetamine; Amphetamines; Anesthetics; Animals; Antidepressive Agents; Catatonia; Cats; Chlorpromazine; Cricetinae; Desipramine; Dextroamphetamine; Epinephrine; Ethanol; Guinea Pigs; Hexobarbital; Histamine; Imipramine; Mice; Neuromuscular Junction; Norepinephrine; Opipramol; Orientation; Pharmacology; Rats; Research; Reserpine; Serotonin; Tetrabenazine; Tremor; Tyramine | 1964 |