desipramine and guanethidine

desipramine has been researched along with guanethidine in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199067 (84.81)18.7374
1990's3 (3.80)18.2507
2000's3 (3.80)29.6817
2010's6 (7.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Petersen, EN1
Angus, JA; Bobik, A; Korner, PI; Stoneham, MT1
Jonsson, CE; Jurell, G1
Burgess, CD; Turner, P; Wadsworth, J1
Tayo, FM1
Key, BJ; Krzywosinski, L1
Chen, CS; Ozawa, H; Uematsu, T; Watanabe, H1
Golko, DS; Huston, LJ; Paton, DM1
Domenech, JS; Garcia, RC; Loyola, AQ; Oroz, JS; Sastain, JM1
Badia, A; Garcia-Sevilla, JA; Laporte, J1
Bevan, JA; Lee, TJ; Su, C1
Cheng, JT; Hsieh-Chen, SC1
Cheng, JT; Shen, CL1
Brock, JA; Cunnane, TC1
Cheng, JT; Shen, CL; Tuan, YH1
DeGraaf, GL; Pals, DT1
von Euler, US1
Antonaccio, MJ1
Miele, E1
Schmitt, H1
Nelson, SR; Walaszek, EJ1
Gascon, AL; Vaillancourt, M1
Buckley, JP; Cavero, I; Clarke, DE; Dixit, BN; Jandhyala, BS1
Renyi, AL; Ross, SB1
Obianwu, HO1
Day, MD; Owen, DA; Warren, PR1
Vapaatalo, HI1
Fozard, JR; Leach, GD1
Fozard, JR1
Clarke, DE1
Saarnivaara, L1
Bouquet, J; Noach, EL1
Chang, CC; Wang, WH1
Antonaccio, MJ; Robson, RD1
Gripenberg, J1
Boullin, DJ; O'Brien, RA1
Juul, P; Sand, O1
Constantine, JW; Koe, BK1
Atkinson, R; Watkinson, B; Weetman, DF1
Bevan, JA; Su, C2
Costa, M; Furness, JB1
Bein, HJ; Maître, L; Staehelin, M1
Feagin, OT; Kaufmann, JS; Mitchell, JR; Oates, JA; Shand, DG1
Burghardt, C; Sheppard, H; Tsien, WH1
Lorez, HP1
Hanahoe, TH; Ireson, JD; Large, BJ1
Mitchell, JR; Oates, JA1
Vohra, MM1
Arias, L; Cavanaugh, JH; Mitchell, JR; Oates, JA1
Bralet, J; Cohen, Y; Jacquot, C; Valette, G1
Arias, L; Mitchell, JR; Oates, JA1
Foster, RW3
Maître, L; Staehelin, M1
Chang, CC; Chiueh, CC1
Hedler, L; Majewski, H; Starke, K1
Clausing, R; Göthert, M; Schlicker, E1
Bell, C1
Cheah, LS; Gwee, MC; Shoon, ML1
Gong, JP; Gopalakrishnakone, P; Gwee, MC1
Fabiani, ME; Story, DF1
BORSY, J; FEKETE, M1
BOFF, E; SCHECKEL, CL1
LUDDEN, CT; PORTER, CC; STAVORSKI, JM; STONE, CA; TOTARO, JA1
ARAMENDIA, P; BASSO, N; KAUMANN, A1
IVERSEN, LL1
CARLSSON, A; WALDECK, B1
CUENCA, E; SALVA, JA; VALDECASAS, FG1
Giraldo, J; Jimenez-Altayo, F; McGrath, JC; Vila, E1
Cao, N; Haynes, JM; Ventura, S1
Fujii, H; Hashikawa-Hobara, N; Kawasaki, H; Mio, M; Miyake, N; Takatori, S; Tangsucharit, P; Zamami, Y1

Reviews

2 review(s) available for desipramine and guanethidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacology of the central nervous system.
    Progress in neurology and psychiatry, 1968, Volume: 23

    Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiotensin II; Animals; Avoidance Learning; Behavior, Animal; Cats; Central Nervous System; Central Nervous System Diseases; Chick Embryo; Desipramine; Dogs; Guanethidine; Guinea Pigs; Humans; Hypnotics and Sedatives; Imipramine; Memory; Mice; Norepinephrine; Parkinson Disease; Phenacetin; Phenothiazines; Phenoxybenzamine; Rabbits; Rats; Reserpine; Serotonin; Sleep; Sleep, REM; Synapses; Synaptic Transmission; Tetrodotoxin; Theophylline

1968

Trials

1 trial(s) available for desipramine and guanethidine

ArticleYear
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
    British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Clomipramine; Depression; Desipramine; Dibenzazepines; Double-Blind Method; Drug Interactions; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mianserin; Propranolol

1978

Other Studies

76 other study(ies) available for desipramine and guanethidine

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
The interaction of desipramine and the 5-HT uptake inhibitors femoxetine and paroxetine with the acute hypotensive effect of guanethidine in conscious spontaneously hypertensive rats.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:9

    Topics: Animals; Anisoles; Blood Pressure; Desipramine; Dioxolanes; Guanethidine; Heart Rate; Hypertension; Piperidines; Rats; Serotonin Antagonists; Time Factors

1979
Guanethidine-induced vasodilatation in the rabbit, mediated by endogenous histamine.
    British journal of pharmacology, 1978, Volume: 62, Issue:1

    Topics: Animals; Desipramine; Drug Interactions; Guanethidine; Hemodynamics; Hindlimb; Histamine; Histamine Antagonists; Histamine Release; In Vitro Techniques; Indomethacin; Male; Mast Cells; Nitroglycerin; p-Methoxy-N-methylphenethylamine; Rabbits; Rats; Regional Blood Flow; Reserpine; Vasodilation

1978
Increased survival of experimental skin flaps in rats following treatment with antiadrenergic drugs.
    Scandinavian journal of plastic and reconstructive surgery, 1976, Volume: 10, Issue:3

    Topics: Adrenergic Agents; Animals; Bretylium Compounds; Desipramine; Female; Graft Survival; Guanethidine; Hydrazines; Hydroxydopamines; Methyltyrosines; Rats; Rats, Inbred Strains; Reserpine; Skin Transplantation; Surgical Flaps

1976
Effects of nomifensine on the isolated vas deferens of the rat.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 240, Issue:1

    Topics: Animals; Desipramine; Dopamine; Drug Interactions; Guanethidine; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Nomifensine; Norepinephrine; Phentolamine; Pimozide; Rats; Serotonin; Vas Deferens

1979
Comparison of the electrocortical changes induced by (+)-amphetamine and chlorpromazine when perfused directly into the dorsal raphé nucleus of the cat.
    British journal of pharmacology, 1978, Volume: 63, Issue:4

    Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Desipramine; Dextroamphetamine; Drug Interactions; Electroencephalography; Guanethidine; Norepinephrine; Perfusion; Raphe Nuclei

1978
Effect of clonidine on blood pressure, heart rate and body temperature in conscious rats.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:1

    Topics: Anesthesia; Animals; Atropine; Blood Pressure; Body Temperature; Chlorpromazine; Clonidine; Desipramine; Drug Synergism; Guanethidine; Heart Rate; Hexamethonium Compounds; Injections, Intravenous; Injections, Subcutaneous; Male; Phentolamine; Rats; Reserpine

1977
Effect of neuronal uptake inhibitors on the adrenergic-neuron blockade produced by guanethidine in rabbit vas deferens.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3

    Topics: Animals; Cocaine; Desipramine; Drug Interactions; Electric Stimulation; Guanethidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Propylamines; Rabbits; Serotonin; Sympathetic Nervous System; Vas Deferens

1977
Pancuronium bromide: an indirect sympathomimetic agent.
    British journal of anaesthesia, 1976, Volume: 48, Issue:12

    Topics: Animals; Blood Pressure; Central Venous Pressure; Desipramine; Dogs; Guanethidine; Heart Ventricles; Norepinephrine; Pancuronium; Reserpine; Sympathomimetics; Tachyphylaxis

1976
Nature of neuronal uptake and noradrenaline--adrenaline effects in the isolated rat vas deferens.
    European journal of pharmacology, 1975, Volume: 31, Issue:2

    Topics: Amantadine; Animals; Cocaine; Computers; Depression, Chemical; Desipramine; Epinephrine; Guanethidine; In Vitro Techniques; Male; Neurons; Norepinephrine; Rats; Vas Deferens

1975
Neurogenic sympathetic vasoconstriction of the rabbit basilar artery.
    Circulation research, 1976, Volume: 39, Issue:1

    Topics: Animals; Basilar Artery; Bretylium Tosylate; Cerebrovascular Circulation; Cocaine; Desipramine; Female; Guanethidine; Male; Microscopy, Fluorescence; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Rabbits; Reserpine; Tetrodotoxin; Vasomotor System

1976
Octopamine relaxes rabbit jejunal smooth muscle by selective activation of dopamine D1 receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:4

    Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Desipramine; Female; Gastrointestinal Motility; Guanethidine; In Vitro Techniques; Jejunum; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Octopamine; Rabbits; Receptors, Adrenergic; Receptors, Dopamine; Tetrodotoxin

1988
Release of neuropeptide Y (NPY) induced by tyramine in the isolated vas deferens of rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:3

    Topics: Animals; Desipramine; Guanethidine; Hydroxydopamines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuropeptide Y; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Synaptosomes; Tyramine; Vas Deferens

1987
Studies on the mode of action of bretylium and guanethidine in post-ganglionic sympathetic nerve fibres.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5

    Topics: Amphetamine; Animals; Autonomic Fibers, Postganglionic; Bretylium Compounds; Bretylium Tosylate; Desipramine; Electrophysiology; Guanethidine; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Tetrodotoxin; Vas Deferens

1988
Characterization of the release of neuropeptide Y (NPY) induced by tyramine from synaptosomal preparations of rabbit jejunum.
    European journal of pharmacology, 1987, Apr-07, Volume: 136, Issue:1

    Topics: Animals; Desipramine; Guanethidine; In Vitro Techniques; Jejunum; L-Lactate Dehydrogenase; Microscopy, Electron; Muscle Proteins; Neuropeptide Y; Norepinephrine; Rabbits; Synaptosomes; Tetrodotoxin; Tyramine

1987
Cardiovascular effects of losulazine hydrochloride, a peripheral norepinephrine-depleting agent, in nonhuman primates.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Chlorisondamine; Desipramine; Dose-Response Relationship, Drug; Guanethidine; Heart Rate; Hemodynamics; Hypotension, Orthostatic; Macaca fascicularis; Male; Nitroprusside; Norepinephrine; Piperazines; Reserpine; Vascular Resistance

1985
Effect of drugs on adrenergic nerve terminals.
    Advances in cytopharmacology, 1971, Volume: 1

    Topics: Amines; Animals; Antidepressive Agents; Axons; Bretylium Compounds; Desipramine; Guanethidine; In Vitro Techniques; Membranes; Monoamine Oxidase Inhibitors; Nerve Endings; Neurotransmitter Agents; Nicotine; Norepinephrine; Reflex; Reserpine; Sulfhydryl Reagents; Sympathetic Nervous System; Sympatholytics; Synaptic Transmission; Tyramine

1971
Paradoxical vagal tachycardia in ganglion-blocked anesthetized dogs.
    European journal of pharmacology, 1974, Volume: 28, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atropine; Blood Pressure; Bretylium Compounds; Chlorisondamine; Debrisoquin; Desipramine; Dogs; Drug Interactions; Electric Stimulation; Female; Ganglionic Blockers; Guanethidine; Heart Rate; Hexamethonium Compounds; Male; Mecamylamine; Methylphenidate; Oxprenolol; Reserpine; Vagus Nerve

1974
On the mechanism of the potentiating of the angiotensin pressor effect by guanethidine and desmethylimipramine.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 15, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Cats; Desipramine; Drug Synergism; Guanethidine; Norepinephrine; Phentolamine; Sympatholytics

1966
[Changes in the hypertensive effects of angiotensin by adrenergic and anti-adrenergic agents].
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 171, Issue:1

    Topics: Amphetamine; Angiotensin II; Animals; Blood Pressure; Bretylium Compounds; Cocaine; Desipramine; Dibenzylchlorethamine; Epinephrine; Female; Guanethidine; Hypertension; Isoproterenol; Male; Metaraminol; Norepinephrine; Normetanephrine; Phenethylamines; Phenoxybenzamine; Phentolamine; Rats; Reserpine; Sympatholytics

1968
Further studies on the mechanism of the musculotropic activity of angiotensin and tyramine on the isolated guinea-pig seminal vesicle.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 180, Issue:1

    Topics: Angiotensin II; Animals; Catecholamines; Cocaine; Desipramine; Epinephrine; Guanethidine; Guinea Pigs; Male; Muscle, Smooth; Norepinephrine; Seminal Vesicles; Tyramine

1969
A differential effect of chronically administered guanethidine on sympathetic neurotransmission to the dog heart and mesenteric arterial blood vessels.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Bretylium Compounds; Chlorisondamine; Cocaine; Desipramine; Dogs; Drug Synergism; Electrodes, Implanted; Guanethidine; Heart; Heart Rate; Hexamethonium Compounds; In Vitro Techniques; Mesenteric Arteries; Monoamine Oxidase; Myocardium; Norepinephrine; Phentolamine; Sympathetic Nervous System; Synaptic Transmission; Vasomotor System

1974
Uptake of some tritiated sympathomimetic amines by mouse brain cortex slices in vitro.
    Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:4

    Topics: Amphetamine; Animals; Brain; Cerebral Cortex; Cocaine; Desipramine; Dopamine; Guanethidine; Hydrazines; In Vitro Techniques; Isoproterenol; Mice; Norepinephrine; Ouabain; Reserpine; Tetrabenazine; Tritium; Tyramine

1966
Inhibition of the dual amine uptake-concentration mechanisms of the adrenergic neurons by epsilon-aminocaproic acid.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:1

    Topics: Amines; Aminocaproates; Animals; Cell Membrane; Desipramine; Guanethidine; Male; Metaraminol; Myocardium; Neurons; Prenylamine; Rats; Reserpine; Tritium

1967
An adrenergic neuron blocking action of propranolol in isolated tissues.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20

    Topics: Amphetamine; Animals; Arteries; Desipramine; Ear; Guanethidine; Ileum; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rabbits; Rats; Vas Deferens

1968
Influence of some drugs on chlorpromazine-induced adrenaline release.
    Annales medicinae experimentalis et biologiae Fenniae, 1968, Volume: 46, Issue:2

    Topics: Adrenal Medulla; Anesthetics, Local; Animals; Atropa belladonna; Cattle; Cell Membrane; Chlorpromazine; Curare; Desipramine; Epinephrine; Female; Guanethidine; Heparin; Hexamethonium Compounds; Histamine H1 Antagonists; In Vitro Techniques; Ouabain; Phenelzine; Plants, Medicinal; Plants, Toxic; Pyrogallol; Spectrophotometry; Sympatholytics; Time Factors

1968
5-HT autopotentiation and drug induced changes in the 5-HT vasomotor response in the pithed rat.
    European journal of pharmacology, 1969, Volume: 7, Issue:1

    Topics: Amphetamine; Animals; Blood Pressure; Bretylium Compounds; Cocaine; Cordotomy; Desipramine; Drug Synergism; Guanethidine; Hydrazines; Male; Methysergide; Norepinephrine; Rats; Reserpine; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Time Factors

1969
Drug induced changes in the distribution of 14C5-HT in the pithed reserpinized rat.
    European journal of pharmacology, 1969, Volume: 7, Issue:3

    Topics: Amphetamine; Animals; Blood Pressure; Bretylium Compounds; Carbon Isotopes; Central Nervous System; Cocaine; Desipramine; Guanethidine; Hydrazines; Kidney; Myocardium; Rats; Reserpine; Serotonin

1969
The effect of bretylium on the cardiovascular response to tyramine in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:1

    Topics: Amphetamine; Animals; Blood Pressure; Bretylium Compounds; Catecholamines; Cordotomy; Desipramine; Drug Synergism; Female; Guanethidine; Heart; Heart Rate; Hydrazines; Myocardium; Nialamide; Norepinephrine; Pentobarbital; Phentolamine; Propranolol; Pyrogallol; Rats; Reserpine; Thiocarbamates; Tyramine; Urethane

1969
Analgesic activity of some sympathetic drugs and their effect on morphine analgesia in rabbits.
    Annales medicinae experimentalis et biologiae Fenniae, 1969, Volume: 47, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analgesia; Animals; Brain; Cocaine; Desipramine; Dopamine; Drug Synergism; Electric Stimulation; Epinephrine; Guanethidine; Isoproterenol; Male; Methoxamine; Methyltyrosines; Morphine; Norepinephrine; Nortriptyline; Pain; Phenoxybenzamine; Rabbits; Sympathomimetics

1969
Some aspects of the adrenergic system of the isolated rat seminal vesicle.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:2

    Topics: Animals; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; Epinephrine; Ethanolamines; Guanethidine; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers, Myelinated; Norepinephrine; Rats; Seminal Vesicles; Tyramine

1971
Antagonism by propranolol of the inhibitory effect of phenoxybenzamine on noradrenaline uptake in vivo.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:12

    Topics: Animals; Binding Sites; Cocaine; Cold Temperature; Desipramine; Drug Antagonism; Female; Guanethidine; Injections, Subcutaneous; Male; Mice; Myocardium; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Time Factors; Tritium

1971
Pharmacological alterations of vagally induced tachycardia in anesthetized dogs.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Animals; Atropine; Blood Pressure; Chlorisondamine; Desipramine; Dogs; Electric Stimulation; Female; Guanethidine; Heart Rate; Hexamethonium Compounds; Male; Norepinephrine; Oxprenolol; Reserpine; Sympathetic Nervous System; Time Factors; Vagus Nerve

1974
Incorporation of imipramine into isolated rat peritoneal mast cells in vitro.
    Acta physiologica Scandinavica, 1974, Volume: 92, Issue:1

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Binding Sites; Calcium; Cell Membrane Permeability; Chlorpromazine; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Female; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Leukocytes; Male; Mast Cells; Nortriptyline; Rats; Receptors, Drug; Reserpine; Serotonin; Temperature

1974
Accumulation, storage and release of adrenergic neuron blocking agents and related drugs by human platelets.
    Biochemical pharmacology, 1972, Jul-01, Volume: 21, Issue:13

    Topics: Amiloride; Binding Sites; Blood Platelets; Carbon Isotopes; Cocaine; Desipramine; Dextroamphetamine; Ethylmaleimide; Guanethidine; Guanidines; Humans; Iodoacetates; Isoquinolines; Ouabain; Parasympatholytics; Quinidine; Reserpine; Serotonin; Tritium

1972
Determination of guanethidine in sympathetic ganglia.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:6

    Topics: Animals; Autoradiography; Cell Survival; Depression, Chemical; Desipramine; Fluorometry; Ganglia, Autonomic; Guanethidine; Half-Life; Male; Neurons; Proadifen; Rats; Reserpine; Stimulation, Chemical; Time Factors

1973
Blocking H 3 -Norepinephrine uptake and some guanethidine-induced effects with tricyclic psychotherapeutic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 195, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Autonomic Fibers, Postganglionic; Benzofurans; Blood Pressure; Cats; Chlorpromazine; Desipramine; Dibenzoxepins; Electric Stimulation; Guanethidine; Heart; Imipramine; Male; Methylamines; Myocardium; Nictitating Membrane; Norepinephrine; Rats; Rats, Inbred Strains; Thioridazine; Tranquilizing Agents; Tritium

1972
The interaction between desmethylimipramine and guanethidine on the rabbit ileum. The importance of the noradrenaline uptake process in the reversal of guanethidine-induced adrenergic neurone blockade.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 198, Issue:2

    Topics: Animals; Biological Transport, Active; Cocaine; Desipramine; Dextroamphetamine; Drug Interactions; Electric Stimulation; Guanethidine; Ileum; In Vitro Techniques; Muscle Contraction; Neuromuscular Junction; Norepinephrine; Rabbits; Receptors, Adrenergic; Tyramine

1972
Uptake of nicotine by the sympathetic nerve terminals in the blood vessel.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:3

    Topics: Animals; Aorta; Autonomic Fibers, Postganglionic; Blood Vessels; Cocaine; Desipramine; Extracellular Space; Guanethidine; In Vitro Techniques; Muscle Contraction; Nerve Endings; Nicotine; Norepinephrine; Pulmonary Artery; Rabbits; Sympathetic Nervous System; Time Factors; Tritium

1972
Storage, uptake and synthesis of catecholamines in the intrinsic adrenergic neurones in the proximal colon of the guinea-pig.
    Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948), 1971, Volume: 120, Issue:3

    Topics: Animals; Catecholamines; Colon; Decarboxylation; Desipramine; Dihydroxyphenylalanine; Female; Fluorescence; Guanethidine; Guinea Pigs; Histocytochemistry; Injections; Male; Microscopy, Fluorescence; Myenteric Plexus; Nerve Tissue; Neurons; Nialamide; Norepinephrine; Normetanephrine; Pargyline; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System; Time Factors

1971
Blockade of noradrenaline uptake by 34276-Ba, a new antidepressant drug.
    Biochemical pharmacology, 1971, Volume: 20, Issue:9

    Topics: Amines; Animals; Anthracenes; Antidepressive Agents; Brain; Cats; Chick Embryo; Desipramine; Dose-Response Relationship, Drug; Guanethidine; Imipramine; In Vitro Techniques; Male; Metaraminol; Myocardium; Neurons; Norepinephrine; Propylamines; Rats; Salivary Glands; Spleen; Time Factors; Tritium; Vas Deferens

1971
Distribution of guanidinium antihypertensives--mechanism of their selective action.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Animals; Antihypertensive Agents; Benzyl Compounds; Biological Transport; Blood Pressure; Desipramine; Drug Antagonism; Guanethidine; Guanidines; Guinea Pigs; Heart; Humans; Hypertension; Kinetics; Myocardium; Neurons; Norepinephrine; Rats; Time Factors; Tyramine

1971
Effect of drugs on the hemolysis of rat erythrocytes.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Desoxycorticosterone; Digitalis Glycosides; Diuretics; Erythrocytes; Glucose; Guanethidine; Hemolysis; Hydrocortisone; Hypotonic Solutions; Indomethacin; Levorphanol; Male; Neostigmine; Rats; Tripelennamine

1969
[Histochemical study of the effect of drugs on the uptake of alpha-methylnoradrenaline by noradrenaline and dopamine containing neurones in rats treated with reserpine].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1969, Volume: 151, Issue:3

    Topics: Animals; Antidepressive Agents; Axons; Cocaine; Desipramine; Dopamine; Dopamine Antagonists; Guanethidine; Histocytochemistry; Hypothalamus; Iris; Male; Mesenteric Veins; Methylphenidate; Microscopy, Fluorescence; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Normetanephrine; Rats; Reserpine; Tripelennamine; Vas Deferens

1969
Interactions between guanethidine and inhibitors of noradrenaline uptake.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: Animals; Desipramine; Drug Antagonism; Electric Stimulation; Guanethidine; Guinea Pigs; Imipramine; Male; Norepinephrine; Phenoxybenzamine; Vas Deferens

1969
Guanethidine and related agents. I. Mechanism of the selective blockade of adrenergic neurons and its antagonism by drugs.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 172, Issue:1

    Topics: Amidines; Animals; Antihypertensive Agents; Bretylium Compounds; Desipramine; Drug Antagonism; Energy Transfer; Guanethidine; Guanidines; Heart; In Vitro Techniques; Isoquinolines; Kinetics; Metaraminol; Myocardium; Neurons; Norepinephrine; Protein Binding; Rats; Sympathetic Nervous System; Tritium; Tyramine

1970
Factors affecting the contractile responses of the rat vas deferens to cocaine and tetracaine.
    Canadian journal of physiology and pharmacology, 1970, Volume: 48, Issue:7

    Topics: Animals; Cocaine; Desipramine; Electric Stimulation; Glucose; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxygen; Rats; Reserpine; Temperature; Tetracaine; Tyramine; Vas Deferens

1970
Guanethidine and related agents. 3. Antagonism by drugs which inhibit the norepinephrine pump in man.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:8

    Topics: Antidepressive Agents; Antihypertensive Agents; Blood Pressure; Desipramine; Drug Antagonism; Guanethidine; Humans; Hypertension; Methyldopa; Norepinephrine; Phentolamine; Pulse; Tyramine

1970
[Effect of stimulation of the sympathetic trunk on liberation of noradrenaline 3H into the rat blood stream: influence of guanethidine, phenoxybenzamine, cocaine and desipramine in vivo].
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 187, Issue:2

    Topics: Adrenalectomy; Animals; Cocaine; Desipramine; Electric Stimulation; Guanethidine; Hexamethonium Compounds; Hypertension; Male; Norepinephrine; Phenoxybenzamine; Rats; Spinal Cord; Stimulation, Chemical; Sympathetic Nervous System; Tritium

1970
Blockade of the nicotine-induced norepinephrine release by cocaine, phenoxybenzamine and desipramine.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: Action Potentials; Animals; Axons; Bretylium Compounds; Cocaine; Desipramine; Electric Stimulation; Guanethidine; Muscle Contraction; Nicotine; Norepinephrine; Phenoxybenzamine; Pulmonary Artery; Rabbits; Reserpine; Tetrodotoxin; Tritium

1970
Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride.
    JAMA, 1967, Dec-04, Volume: 202, Issue:10

    Topics: Antidepressive Agents; Antihypertensive Agents; Blood Pressure; Desipramine; Drug Antagonism; Guanethidine; Humans; Hypertension

1967
A correlation between inhibition of the uptake of 3H from (+)-3H-noradrenaline and potentiation of the responses to (-)-noradrenaline in the guinea-pig isolated trachea.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Animals; Carbon Isotopes; Cocaine; Desipramine; Drug Synergism; Guanethidine; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Sorbitol; Temperature; Trachea; Tritium

1968
Enhancement of H3-norepinephrine accumulation in rat vas deferens by cocaine, imipramine, and desmethylimipramine.
    Experientia, 1968, Jul-15, Volume: 24, Issue:7

    Topics: Animals; Cocaine; Desipramine; Guanethidine; Imipramine; Male; Metaraminol; Myocardium; Norepinephrine; Rats; Reserpine; Stimulation, Chemical; Tritium; Vas Deferens

1968
An uptake of radioactivity from (plus or minus)-3H-isoprenaline and its inhibition by drugs which potentiate the responses to (minus)-isoprenaline in the guinea-pig isolated trachea.
    British journal of pharmacology, 1969, Volume: 35, Issue:3

    Topics: Animals; Cocaine; Cold Temperature; Desipramine; Drug Synergism; Epinephrine; Guanethidine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Phenoxybenzamine; Phentolamine; Trachea; Tritium

1969
Modulation of noradrenaline incorporation by nerve activities in the rat submaxillary gland.
    The Journal of physiology, 1969, Volume: 203, Issue:1

    Topics: Animals; Desipramine; Dopamine; Electric Stimulation; Epinephrine; Female; Guanethidine; Male; Norepinephrine; Normetanephrine; Phenoxybenzamine; Rats; Reserpine; Submandibular Gland; Sympathetic Nervous System; Tritium

1969
The potentiation of the responses to noradrenaline and isoprenaline of the guinea-pig isolated tracheal chain preparation by desipramine, cocaine, phentolamine, phenoxybenzamine, guanethidine, metanephrine and cooling.
    British journal of pharmacology and chemotherapy, 1967, Volume: 31, Issue:3

    Topics: Animals; Cocaine; Culture Techniques; Desipramine; Drug Synergism; Epinephrine; Female; Guanethidine; Guinea Pigs; Hormones; Indoles; Isocarboxazid; Isoproterenol; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Pyridines; Pyrogallol; Temperature; Thiosulfates; Time Factors; Trachea; Tyramine

1967
Evidence for a physiological role of presynaptic alpha-adrenoceptors: modulation of noradrenaline release in the pithed rabbit.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Electric Stimulation; Epinephrine; Female; Guanethidine; Heart Rate; Male; Nordefrin; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spinal Nerves; Yohimbine

1983
Acute or chronic changes of noradrenergic transmission do not affect the alpha-adrenoceptor-mediated inhibition of 3H-serotonin release in the cerebral cortex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 320, Issue:1

    Topics: Animals; Cerebral Cortex; Desipramine; Drug Interactions; Guanethidine; Hydroxydopamines; Male; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synaptic Transmission

1982
Benztropine-induced prolongation of responses to vasodilator nerve stimulation in the canine paw pad.
    British journal of pharmacology, 1982, Volume: 76, Issue:2

    Topics: Animals; Benztropine; Desipramine; Dogs; Electric Stimulation; Foot; Guanethidine; Regional Blood Flow; Time Factors; Tropanes; Vasodilation; Vasomotor System

1982
Prejunctional and postjunctional inhibition of adrenergic transmission in the rat-isolated anococcygeus muscle by cimetidine.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:3

    Topics: Animals; Cimetidine; Desipramine; Electric Stimulation; Guanethidine; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neuromuscular Junction; Ranitidine; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Tyramine

1995
Buthus martensi karsch venom: prejunctional adrenergic activity in the rat isolated anococcygeus muscle.
    Toxicon : official journal of the International Society on Toxinology, 1995, Volume: 33, Issue:9

    Topics: Animals; Desipramine; Electric Stimulation; Guanethidine; In Vitro Techniques; Injections, Subcutaneous; Male; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Norepinephrine; Phentolamine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Reserpine; Scorpion Venoms; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin; Tyramine

1995
Inhibition of sympathetic noradrenergic transmission by guanabenz and guanethidine in rat isolated mesenteric artery: involvement of neuronal potassium channels.
    Pharmacological research, 1996, Volume: 33, Issue:3

    Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Apamin; Desipramine; Drug Interactions; Female; Guanabenz; Guanethidine; Idazoxan; In Vitro Techniques; Male; Mesenteric Arteries; Neurons, Efferent; Norepinephrine; Pargyline; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Synaptic Transmission; Tritium

1996
ON THE ANTIARRHYTHMIC EFFECT OF SOME THYMOLEPTICS (AMITRIPTYLINE, IMIPRAMINE, TRIMEPROPIMINE AND DESMETHYLIMIPRAMINE).
    Medicina experimentalis : International journal of experimental medicine, 1964, Volume: 10

    Topics: Aconitum; Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Bradycardia; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Chlorides; Desipramine; Electrocardiography; Guanethidine; Imipramine; Pharmacology; Quinidine; Rats; Research; Reserpine; Tachycardia; Ventricular Fibrillation

1964
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
    Psychopharmacologia, 1964, Feb-12, Volume: 5

    Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine

1964
ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 144

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Electrophysiology; Guanethidine; Imipramine; Metaraminol; Methylphenidate; Mice; Myocardium; Nictitating Membrane; Norepinephrine; Pharmacology; Piperidines; Promazine; Research; Reserpine; Tripelennamine; Tyrosine

1964
THE CARDIOVASCULAR EFFECTS OF N-(GAMMA-METHYLAMINOPROPYL-IMINO-DIBENZYL)-HCL (DESMETHYLIMIPRAMINE) AND GUANETHIDINE.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 147

    Topics: Antidepressive Agents; Blood Pressure; Cardiovascular System; Desipramine; Dogs; Epinephrine; Guanethidine; Heart; Heart Rate; Isoproterenol; Norepinephrine; Pharmacology; Research; Reserpine; Tyramine; Vagotomy

1965
INHIBITION OF NORADRENALINE UPTAKE BY DRUGS.
    The Journal of pharmacy and pharmacology, 1965, Volume: 17

    Topics: Bretylium Compounds; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Guanethidine; Heart; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Pharmacology; Rats; Research; Reserpine; Sympatholytics

1965
MECHANISM OF AMINE TRANSPORT IN THE CELL MEMBRANES OF THE ADRENERGIC NERVES.
    Acta pharmacologica et toxicologica, 1965, Volume: 22

    Topics: Adrenergic Agents; Amines; Animals; Biological Transport; Cell Membrane; Desipramine; Guanethidine; Metabolism; Metaraminol; Mice; Muscles; Myocardium; Norepinephrine; Octopamine; Pharmacology; Prenylamine; Research; Reserpine; Sympathetic Nervous System; Tritium

1965
SOME PHARMACOLOGICAL EFFECTS OF DESMETHYLIMIPRAMINE (DMI).
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Acetylcholine; Amphetamine; Amphetamines; Blood Pressure; Bretylium Compounds; Cats; Desipramine; Guanethidine; Nerve Endings; Norepinephrine; Pharmacology; Reflex; Research; Sympathetic Nervous System; Tyramine

1964
Enhanced noradrenergic transmission in the spontaneously hypertensive rat anococcygeus muscle.
    British journal of pharmacology, 2003, Volume: 140, Issue:4

    Topics: Animals; Blotting, Western; Carbachol; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; Male; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Phentolamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sacrococcygeal Region; Synaptic Transmission; Tyrosine 3-Monooxygenase; Yohimbine

2003
Saw palmetto is an indirectly acting sympathomimetic in the rat-isolated prostate gland.
    The Prostate, 2006, Feb-01, Volume: 66, Issue:2

    Topics: Amphetamine; Animals; Cocaine; Desipramine; Electric Stimulation; Guanethidine; Male; Nifedipine; Phentolamine; Plant Extracts; Prazosin; Prostate; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Serenoa; Sympathomimetics; Tyramine; Urinary Bladder; Vas Deferens

2006
Adrenergic stimulation-released 5-HT stored in adrenergic nerves inhibits CGRPergic nerve-mediated vasodilatation in rat mesenteric resistance arteries.
    British journal of pharmacology, 2012, Volume: 166, Issue:7

    Topics: Adrenergic Agents; Adrenergic Neurons; Adrenergic Uptake Inhibitors; Animals; Calcitonin Gene-Related Peptide; Desipramine; Fluoxetine; Guanethidine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Vasoconstriction; Vasodilation

2012