desipramine has been researched along with fluvoxamine in 76 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (7.89) | 18.7374 |
1990's | 30 (39.47) | 18.2507 |
2000's | 22 (28.95) | 29.6817 |
2010's | 18 (23.68) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Topliss, JG; Yoshida, F | 1 |
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
Camp, VM; Chen, P; Ely, TD; Galt, J; Goodman, MM; Howell, L; Kilts, CD; Malveaux, G; Martarello, L; McConathy, J; Nemeroff, CB; Plisson, C; Shi, B; Votaw, JR | 1 |
Dansette, PM; Fontana, E; Poli, SM | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Mos, J; Olivier, B; Tilders, FJ; Van Dijken, HH | 1 |
Durlach-Misteli, C; Van Ree, JM | 1 |
Avenoso, A; Campo, GM; Caputi, AP; Pollicino, MA; Spina, E | 1 |
Kapur, S; Mann, JJ | 1 |
Coquoz, D; Dayer, P; Porchet, HC | 2 |
Grochocinski, VJ; Kupfer, DJ; McEachran, AB; Nathan, RS; Perel, JM; Pollock, BG; Wilson, MJ | 1 |
Bradshaw, CM; Shah, K; Szabadi, E | 1 |
Charney, DS; Delgado, PL; Goodman, WK; Heninger, GR; Krystal, JH; Nagy, LM; Palumbo, J; Price, LH; Rasmussen, SA | 1 |
Kupfer, DJ; Nathan, RS; Perel, JM; Pollock, BG | 1 |
Schneider, L; Tynes, LL; White, K; Wykoff, W; Zemansky, M | 1 |
Mattes, J; Roth, D; Sheehan, DV; Sheehan, KH | 1 |
Anderson, GM; Charney, DS; Delgado, PL; Heninger, GR; Price, LH | 1 |
Bovier, P; Gaillard, JM; Tissot, R; Widmer, J | 1 |
Durcan, MJ; Eckardt, MJ; Linnoila, M; Lister, RG | 2 |
Harms, HH | 1 |
Bradford, D; Krijzer, F; Snelder, M | 1 |
Egawa, T; Ichimaru, Y; Imanishi, T; Sawa, A | 1 |
Court, MH; Duan, SX; Greenblatt, DJ; Harmatz, JS; Shader, RI; von Moltke, LL | 1 |
Benjamin, J; Kaplan, Z; Zohar, J | 1 |
Arendt, J; Bojkowski, CJ; Skene, DJ | 1 |
Avenoso, A; Campo, GM; Caputi, AP; Pollicino, AM; Spina, E | 1 |
Avenoso, A; Campo, GM; Caputi, AP; Perucca, E; Pollicino, AM; Spina, E | 1 |
Joffe, RT; Schuller, DR | 1 |
Goodman, WK; McDougle, CJ; Price, LH | 1 |
Alhaider, AA; Mustafa, AA | 1 |
al-Zahrani, SS; Bradshaw, CM; Ho, MY; Lopez Cabrera, M; Szabadi, E; Velazquez Martinez, DN | 1 |
Artigas, F; Bel, N | 1 |
Chover, AJ; Gibert-Rahola, J; Mellado-Fernández, ML; Micó, JA; Ortega-Alvaro, A | 1 |
Bergeron, R; Blier, P; de Montigny, C | 1 |
Bourin, M; Redrobe, JP | 1 |
Ahern, D; Ball, SE; Kao, J; Scatina, J | 1 |
Anand, A; Barr, LC; Goodman, WK; McDougle, CJ; Price, LH | 1 |
Huang, SL; Xu, ZH; Zhou, HH | 1 |
Benmansour, S; Cecchi, M; Frazer, A; Gerhardt, GA; Gould, GG; Javors, MA; Morilak, DA | 1 |
Silver, H; Youdim, MB | 1 |
Gavish, M; Leschiner, S; Shoukrun, R; Veenman, L; Weizman, R | 1 |
Norrholm, SD; Ouimet, CC | 1 |
Baba, J; Fujishiro, J; Imanishi, T; Kosaka, K | 1 |
Daws, LC; Gould, GG; Montañez, S; Murphy, DL; Owens, WA | 1 |
Kamei, J; Miyata, S; Morita, K; Saitoh, A; Takeda, H | 1 |
Ben-Amir, E; Doljansky, J; Flaisher, S; Joel, D | 1 |
Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO | 1 |
Avissar, S; Matuzany-Ruban, A; Schreiber, G; Tzukert, K | 1 |
Ginsburg, BC; Lamb, RJ | 3 |
Gibert-Rahola, J; Mico, JA; Rojas-Corrales, MO | 1 |
Hirano, K; Hotta, Y; Kajiwara, Y; Kobayashi, Y; Sugimoto, Y; Tagawa, N; Yamada, J; Yamada, S | 1 |
Bachis, A; Cruz, MI; Mallei, A; Mocchetti, I; Wellstein, A | 1 |
Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S | 1 |
Aburakawa, Y; Aizawa, H; Hasebe, N; Kwak, S; Sawada, J; Yamashita, T | 1 |
Balci, F; Campbell, U; Hanania, T; Olivier, BE; Paterson, NE | 1 |
Hara, H; Hayashi, E; Kinoshita, M; Kuratani, K; Shimamura, M | 1 |
Barak, Y; Baratz-Goldstein, R; Hostovsky, A; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I | 1 |
Bergqvist, F; Demirbugen, M; Dunnett, SB; Lane, EL; Lindgren, HS | 1 |
Preskorn, SH | 1 |
Ago, Y; Hasebe, S; Hashimoto, H; Matsuda, T; Nishiyama, S; Oka, S; Takuma, K | 1 |
Dallé, E; Daniels, WM; Mabandla, MV | 1 |
Daws, LC; Koek, W; Sandoval, TL | 1 |
Matsumoto, M; Niwa, T; Shizuku, M; Yanai, M | 1 |
Chierrito, D; Fernandez-Llimos, F; Sanches, ACC; Tonin, FS; Villas-Boas, CB | 1 |
6 review(s) available for desipramine and fluvoxamine
Article | Year |
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Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The emergence of suicidal ideation and behavior during antidepressant pharmacotherapy.
Topics: Antidepressive Agents; Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Fluvoxamine; Humans; Imipramine; Mianserin; Suicide | 1991 |
The pharmacotherapy of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Buspirone; Clomipramine; Desipramine; Fluoxetine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Sertraline | 1993 |
Clinical psychopharmacology and medical malpractice: the four Ds.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Depressive Disorder; Desipramine; Fatal Outcome; Female; Fluvoxamine; Forensic Psychiatry; Humans; Imipramine; Male; Malpractice; Mental Disorders; Psychopharmacology; Schizophrenia; Thioridazine | 2014 |
Pharmacological treatment of attention-deficit hyperactivity disorder comorbid with an anxiety disorder: a systematic review.
Topics: Adolescent; Adult; Anxiety Disorders; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Central Nervous System Agents; Child; Comorbidity; Desipramine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Methylphenidate; Randomized Controlled Trials as Topic; Treatment Outcome | 2019 |
11 trial(s) available for desipramine and fluvoxamine
Article | Year |
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[Central analgesic effects of antidepressant drugs with various mechanisms of action: desipramine, fluvoxamine and moclobemide].
Topics: Analgesics; Antidepressive Agents; Benzamides; Desipramine; Double-Blind Method; Electric Stimulation; Fluvoxamine; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Pain; Sural Nerve | 1991 |
Fluvoxamine versus desipramine: comparative polysomnographic effects.
Topics: Adult; Antidepressive Agents; Arousal; Delta Rhythm; Depressive Disorder; Desipramine; Double-Blind Method; Electroencephalography; Female; Fluvoxamine; Humans; Male; Middle Aged; Oximes; Signal Processing, Computer-Assisted; Sleep, REM | 1991 |
Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine.
Topics: Adult; Anxiety Disorders; Basal Ganglia; Depressive Disorder; Desipramine; Dopamine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Oximes; Panic; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1990 |
The role of neuropharmacologic selectivity in antidepressant action: fluvoxamine versus desipramine.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Norepinephrine; Oximes; Personality Inventory; Psychiatric Status Rating Scales; Serotonin; Serotonin Antagonists | 1990 |
Fluvoxamine in the treatment of tricyclic-resistant depression.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Middle Aged; Oximes; Psychiatric Status Rating Scales; Serotonin Antagonists | 1990 |
A double-blind comparison of fluvoxamine, desipramine and placebo in outpatients with depression.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Fluvoxamine; Humans; Outpatients; Oximes; Placebos; Psychiatric Status Rating Scales; Random Allocation | 1990 |
Effects of desipramine and fluvoxamine treatment on the prolactin response to tryptophan. Serotonergic function and the mechanism of antidepressant action.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Fluvoxamine; Humans; Oximes; Prolactin; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan | 1989 |
Comparison of the effects of acute fluvoxamine and desipramine administration on melatonin and cortisol production in humans.
Topics: Adult; Analysis of Variance; Desipramine; Fluvoxamine; Humans; Hydrocortisone; Male; Melatonin; Radioimmunoassay | 1994 |
An open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression.
Topics: Adult; Ambulatory Care; Buspirone; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors | 1993 |
Central analgesic effects of desipramine, fluvoxamine, and moclobemide after single oral dosing: a study in healthy volunteers.
Topics: Administration, Oral; Adult; Analgesics; Analysis of Variance; Benzamides; Desipramine; Double-Blind Method; Fluvoxamine; Humans; Male; Moclobemide; Reference Values | 1993 |
Addition of desipramine to serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Adult; Clomipramine; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome | 1997 |
59 other study(ies) available for desipramine and fluvoxamine
Article | Year |
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QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Female; HeLa Cells; Humans; Iodine Radioisotopes; Isotope Labeling; Ligands; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2003 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Effects of anxiolytic and antidepressant drugs on long-lasting behavioural deficits resulting from one short stress experience in male rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Desipramine; Diazepam; Electroshock; Fluvoxamine; Male; Motor Activity; Noise; Piperazines; Rats; Rats, Wistar; Serotonin Receptor Agonists; Stress, Psychological | 1992 |
Dopamine and melatonin in the nucleus accumbens may be implicated in the mode of action of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluvoxamine; Male; Melatonin; Mianserin; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Dopamine; Sensitivity and Specificity | 1992 |
Interaction between fluvoxamine and imipramine/desipramine in four patients.
Topics: Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged | 1992 |
Interaction between antidepressants and d-amphetamine on variable-interval performance.
Topics: Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Fluvoxamine; Imipramine; Oximes; Psychomotor Performance; Rats; Rats, Inbred Strains; Reinforcement Schedule; Serotonin Antagonists; Trazodone | 1990 |
Evolution of red blood cell membrane transport and plasma level of L-tyrosine and L-tryptophan in depressed treated patients according to clinical improvement.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocyte Membrane; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Psychological Tests; Tryptophan; Tyrosine | 1988 |
Interactions of 5HT reuptake inhibitors and ethanol in tests of exploration and anxiety.
Topics: Animals; Anxiety; Citalopram; Desipramine; Drug Interactions; Ethanol; Exploratory Behavior; Fluoxetine; Fluvoxamine; Mice; Mice, Inbred Strains; Motor Activity; Oximes; Serotonin Antagonists | 1988 |
Behavioral interactions of fluoxetine and other 5-hydroxytryptamine uptake inhibitors with ethanol in tests of anxiety, locomotion and exploration.
Topics: Animals; Anxiety; Citalopram; Desipramine; Ethanol; Exploratory Behavior; Fluoxetine; Fluvoxamine; Male; Mice; Motor Activity; Oximes; Serotonin Antagonists | 1988 |
The antidepressant agents desipramine, fluoxetine, fluvoxamine and norzimelidine inhibit uptake of [3H]noradrenaline and [3H]5-hydroxytryptamine in slices of human and rat cortical brain tissue.
Topics: Absorption; Animals; Antidepressive Agents; Cerebral Cortex; Desipramine; Fluoxetine; Fluvoxamine; Humans; In Vitro Techniques; Male; Norepinephrine; Oximes; Rats; Serotonin; Zimeldine | 1983 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fluvoxamine; Imipramine; Male; Maprotiline; Mianserin; Oximes; Rats; Rats, Inbred Strains; Seizures; Viloxazine | 1984 |
Neither the 5-HT1A- nor the 5-HT2-receptor subtype mediates the effect of fluvoxamine, a selective serotonin reuptake inhibitor, on forced-swimming-induced immobility in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Desipramine; Disease Models, Animal; Drug Interactions; Fluvoxamine; Male; Mice; Mice, Inbred ICR; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin Antagonists | 1995 |
Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants.
Topics: Alprazolam; Biotransformation; Culture Techniques; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Dose-Response Relationship, Drug; Fluvoxamine; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors | 1995 |
Compulsive exhibitionism successfully treated with fluvoxamine: a controlled case study.
Topics: Adult; Desipramine; Exhibitionism; Fluvoxamine; Humans; Male; Masturbation; Obsessive-Compulsive Disorder; Placebos; Psychiatric Status Rating Scales; Single-Blind Method; Treatment Outcome | 1994 |
Fluvoxamine-induced alterations in plasma concentrations of imipramine and desipramine in depressed patients.
Topics: Adult; Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged | 1993 |
Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects.
Topics: Adult; Desipramine; Drug Interactions; Fluvoxamine; Humans; Imipramine; Male | 1993 |
Differential effects of fluoxetine on isoprenaline-stimulated water intake in ethanol-treated rats: a role for beta-adrenoceptors.
Topics: Analysis of Variance; Animals; Desipramine; Drinking; Drug Interactions; Ethanol; Fluoxetine; Fluvoxamine; Injections, Intraperitoneal; Isoproterenol; Male; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Zimeldine | 1993 |
Effects of desipramine and fluvoxamine on timing behavior investigated with the fixed-interval peak procedure and the interval bisection task.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Conditioning, Operant; Desipramine; Female; Fluvoxamine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Time Factors | 1996 |
In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies.
Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cerebral Cortex; Citalopram; Clonidine; Desipramine; Fluoxetine; Fluvoxamine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1996 |
The effects of different monoaminergic antidepressants on the analgesia induced by spinal cord adrenal medullary transplants in the formalin test in rats.
Topics: Adrenal Medulla; Amitriptyline; Analgesia; Animals; Antidepressive Agents; Desipramine; Fluvoxamine; Formaldehyde; Male; Rats; Rats, Wistar; Spinal Cord | 1997 |
Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Buspirone; Depressive Disorder; Desipramine; Drug Synergism; Female; Fluvoxamine; Humans; Male; Pindolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Trimipramine | 1997 |
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 1997 |
Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclohexanols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Fluoxetine; Fluvoxamine; Frozen Sections; Humans; Hydroxylation; Imipramine; In Vitro Techniques; Lethal Dose 50; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Venlafaxine Hydrochloride | 1997 |
Inhibition of imipramine N-demethylation by fluvoxamine in Chinese young men.
Topics: Adult; Antidepressive Agents, Tricyclic; Area Under Curve; Desipramine; Drug Interactions; Fluvoxamine; Humans; Imipramine; Male; Selective Serotonin Reuptake Inhibitors | 1996 |
Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Carrier Proteins; Desipramine; Fluvoxamine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Paroxetine; Phenelzine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sertraline; Time Factors | 1999 |
MAO-A and MAO-B activities in rat striatum, frontal cortex and liver are unaltered after long-term treatment with fluvoxamine and desipramine.
Topics: Animals; Blood Platelets; Corpus Striatum; Desipramine; Fluvoxamine; Frontal Lobe; Humans; Isoenzymes; Liver; Male; Monoamine Oxidase; Rats; Rats, Sprague-Dawley | 2000 |
Tissue-specific regulation of the peripheral benzodiazepine receptor by antidepressants and lithium.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Cerebral Cortex; Desipramine; Fluvoxamine; Lithium Carbonate; Male; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2000 |
Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine proliferation in hippocampus.
Topics: Adrenergic Uptake Inhibitors; Animals; Cell Count; Dendrites; Desipramine; Fluoxetine; Fluvoxamine; Hippocampus; Male; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 2000 |
Comparison of noradrenergic and serotonergic antidepressants in reducing immobility time in the tail suspension test.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Fluoxetine; Fluvoxamine; Male; Models, Animal; Nortriptyline; Rats; Rats, Inbred Strains; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission; Tail | 2001 |
Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Carrier Proteins; Desipramine; Dose-Response Relationship, Drug; Drug Administration Routes; Fluvoxamine; Heterozygote; Hippocampus; Homozygote; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 2003 |
Effects of selective serotonin reuptake inhibitors on immobility time in the tail suspension test in streptozotocin-induced diabetic mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Desipramine; Diabetes Mellitus, Experimental; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Hindlimb Suspension; Male; Mice; Mice, Inbred ICR; Motor Activity; Selective Serotonin Reuptake Inhibitors | 2003 |
'Compulsive' lever-pressing in rats is attenuated by the serotonin re-uptake inhibitors paroxetine and fluvoxamine but not by the tricyclic antidepressant desipramine or the anxiolytic diazepam.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Compulsive Behavior; Conditioning, Operant; Desipramine; Diazepam; Dose-Response Relationship, Drug; Extinction, Psychological; Fluvoxamine; Male; Paroxetine; Rats; Rats, Wistar; Reward; Selective Serotonin Reuptake Inhibitors | 2004 |
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; Desipramine; Fluvoxamine; Levorphanol; Male; Methadone; Mice; Morphine; Narcotics; Reserpine; Stereoisomerism; Time Factors; Tramadol; Venlafaxine Hydrochloride | 2004 |
Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain.
Topics: Adult; Aged; Animals; Antidepressive Agents; Arrestins; beta-Arrestin 1; beta-Arrestins; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Depressive Disorder; Desipramine; Down-Regulation; Female; Fluvoxamine; Hippocampus; Humans; Imipramine; Leukocytes, Mononuclear; Male; Middle Aged; Psychiatric Status Rating Scales; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Severity of Illness Index | 2004 |
Fluvoxamine and desipramine on fixed-ratio responding: effects of reinforcement magnitude.
Topics: Adrenergic Uptake Inhibitors; Animals; Columbidae; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Fluvoxamine; Food; Reinforcement Schedule; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors | 2005 |
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Indophenol; Levorphanol; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Stereotyped Behavior; Tics; Tourette Syndrome; Tramadol; Triazoles | 2007 |
Reinforcement magnitude modulates the rate-dependent effects of fluvoxamine and desipramine on fixed-interval responding in the pigeon.
Topics: Adrenergic Uptake Inhibitors; Animals; Columbidae; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Fluvoxamine; Food; Male; Reinforcement Schedule; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors | 2008 |
Mouse strain differences in immobility and sensitivity to fluvoxamine and desipramine in the forced swimming test: analysis of serotonin and noradrenaline transporter binding.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Swimming | 2008 |
Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Blotting, Western; Cell Nucleus; Cytosol; Desipramine; Fibroblast Growth Factor 2; Fluvoxamine; Immunohistochemistry; Isomerism; Male; Neurons; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; Selective Serotonin Reuptake Inhibitors | 2008 |
Reinforcement magnitude modulation of rate-dependent effects of fluvoxamine and desipramine in the rat.
Topics: Animals; Antidepressive Agents; Conditioning, Operant; Desipramine; Feeding Behavior; Fluvoxamine; Male; Rats; Rats, Inbred Lew; Regression Analysis; Reinforcement Schedule; Reinforcement, Psychology | 2008 |
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Ischemia; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluvoxamine; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Milnacipran; Motor Activity; Rats; Rats, Wistar | 2009 |
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2009 |
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.
Topics: Animals; Antidepressive Agents; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bupropion; Desipramine; Diazepam; Dopamine Uptake Inhibitors; Fluvoxamine; Haloperidol; Imipramine; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology | 2011 |
Automated experimental system capturing three behavioral components during murine forced swim test.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Bupropion; Desipramine; Equipment Design; Fluvoxamine; Image Interpretation, Computer-Assisted; Imipramine; Male; Mice; Mice, Inbred Strains; Pattern Recognition, Automated; Psychomotor Performance; Swimming; Video Recording | 2011 |
Interaction of different antidepressants with acute and chronic methadone in mice, and possible clinical implications.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Citalopram; Clomipramine; Cyclohexanols; Desipramine; Drug Interactions; Fluvoxamine; Male; Methadone; Mice; Mice, Inbred ICR; Morpholines; Nociception; Pain Threshold; Reboxetine; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride | 2014 |
The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions.
Topics: Adrenergic Uptake Inhibitors; Animals; Brain Injuries; Cell Count; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Female; Fluvoxamine; Functional Laterality; Movement; Nerve Fibers; Norepinephrine; Oxidopamine; Rats; Reaction Time; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 2014 |
Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice.
Topics: Animals; Animals, Outbred Strains; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Desipramine; Duloxetine Hydrochloride; Fluvoxamine; Hydroxycorticosteroids; Idazoxan; Indoles; Male; Mice; Motor Activity; Neuropsychological Tests; Oxazines; Paroxetine; Piperazines; Psychotropic Drugs; Pyridines; Risperidone; Ritanserin; Social Behavior; Social Isolation; Sulfonamides; Venlafaxine Hydrochloride | 2015 |
Fluvoxamine maleate normalizes striatal neuronal inflammatory cytokine activity in a Parkinsonian rat model associated with depression.
Topics: Age Factors; Animals; Animals, Newborn; Anti-Anxiety Agents; Corpus Striatum; Cytokines; Depression; Desipramine; Disease Models, Animal; Fluvoxamine; Functional Laterality; Lipid Peroxidation; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Psychomotor Performance; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sucrose | 2017 |
Effects of the antidepressants desipramine and fluvoxamine on latency to immobility and duration of immobility in the forced swim test in adult male C57BL/6J mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Desipramine; Disease Models, Animal; Fluoxetine; Fluvoxamine; Immobilization; Male; Mice; Mice, Inbred C57BL; Motor Activity; Swimming | 2018 |
Effect of Cytochrome P450 (CYP) 2D6 Genetic Polymorphism on the Inhibitory Action of Antidepressants on CYP2D6-Mediated Dopamine Formation from p-Tyramine.
Topics: Antidepressive Agents; Brain; Cytochrome P-450 CYP2D6; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluvoxamine; Humans; Imipramine; Polymorphism, Genetic; Structure-Activity Relationship; Tyramine | 2018 |