desipramine and fluvoxamine

desipramine has been researched along with fluvoxamine in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19906 (7.89)18.7374
1990's30 (39.47)18.2507
2000's22 (28.95)29.6817
2010's18 (23.68)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Camp, VM; Chen, P; Ely, TD; Galt, J; Goodman, MM; Howell, L; Kilts, CD; Malveaux, G; Martarello, L; McConathy, J; Nemeroff, CB; Plisson, C; Shi, B; Votaw, JR1
Dansette, PM; Fontana, E; Poli, SM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mos, J; Olivier, B; Tilders, FJ; Van Dijken, HH1
Durlach-Misteli, C; Van Ree, JM1
Avenoso, A; Campo, GM; Caputi, AP; Pollicino, MA; Spina, E1
Kapur, S; Mann, JJ1
Coquoz, D; Dayer, P; Porchet, HC2
Grochocinski, VJ; Kupfer, DJ; McEachran, AB; Nathan, RS; Perel, JM; Pollock, BG; Wilson, MJ1
Bradshaw, CM; Shah, K; Szabadi, E1
Charney, DS; Delgado, PL; Goodman, WK; Heninger, GR; Krystal, JH; Nagy, LM; Palumbo, J; Price, LH; Rasmussen, SA1
Kupfer, DJ; Nathan, RS; Perel, JM; Pollock, BG1
Schneider, L; Tynes, LL; White, K; Wykoff, W; Zemansky, M1
Mattes, J; Roth, D; Sheehan, DV; Sheehan, KH1
Anderson, GM; Charney, DS; Delgado, PL; Heninger, GR; Price, LH1
Bovier, P; Gaillard, JM; Tissot, R; Widmer, J1
Durcan, MJ; Eckardt, MJ; Linnoila, M; Lister, RG2
Harms, HH1
Bradford, D; Krijzer, F; Snelder, M1
Egawa, T; Ichimaru, Y; Imanishi, T; Sawa, A1
Court, MH; Duan, SX; Greenblatt, DJ; Harmatz, JS; Shader, RI; von Moltke, LL1
Benjamin, J; Kaplan, Z; Zohar, J1
Arendt, J; Bojkowski, CJ; Skene, DJ1
Avenoso, A; Campo, GM; Caputi, AP; Pollicino, AM; Spina, E1
Avenoso, A; Campo, GM; Caputi, AP; Perucca, E; Pollicino, AM; Spina, E1
Joffe, RT; Schuller, DR1
Goodman, WK; McDougle, CJ; Price, LH1
Alhaider, AA; Mustafa, AA1
al-Zahrani, SS; Bradshaw, CM; Ho, MY; Lopez Cabrera, M; Szabadi, E; Velazquez Martinez, DN1
Artigas, F; Bel, N1
Chover, AJ; Gibert-Rahola, J; Mellado-Fernández, ML; Micó, JA; Ortega-Alvaro, A1
Bergeron, R; Blier, P; de Montigny, C1
Bourin, M; Redrobe, JP1
Ahern, D; Ball, SE; Kao, J; Scatina, J1
Anand, A; Barr, LC; Goodman, WK; McDougle, CJ; Price, LH1
Huang, SL; Xu, ZH; Zhou, HH1
Benmansour, S; Cecchi, M; Frazer, A; Gerhardt, GA; Gould, GG; Javors, MA; Morilak, DA1
Silver, H; Youdim, MB1
Gavish, M; Leschiner, S; Shoukrun, R; Veenman, L; Weizman, R1
Norrholm, SD; Ouimet, CC1
Baba, J; Fujishiro, J; Imanishi, T; Kosaka, K1
Daws, LC; Gould, GG; Montañez, S; Murphy, DL; Owens, WA1
Kamei, J; Miyata, S; Morita, K; Saitoh, A; Takeda, H1
Ben-Amir, E; Doljansky, J; Flaisher, S; Joel, D1
Berrocoso, E; Gibert-Rahola, J; Micó, JA; Rojas-Corrales, MO1
Avissar, S; Matuzany-Ruban, A; Schreiber, G; Tzukert, K1
Ginsburg, BC; Lamb, RJ3
Gibert-Rahola, J; Mico, JA; Rojas-Corrales, MO1
Hirano, K; Hotta, Y; Kajiwara, Y; Kobayashi, Y; Sugimoto, Y; Tagawa, N; Yamada, J; Yamada, S1
Bachis, A; Cruz, MI; Mallei, A; Mocchetti, I; Wellstein, A1
Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S1
Aburakawa, Y; Aizawa, H; Hasebe, N; Kwak, S; Sawada, J; Yamashita, T1
Balci, F; Campbell, U; Hanania, T; Olivier, BE; Paterson, NE1
Hara, H; Hayashi, E; Kinoshita, M; Kuratani, K; Shimamura, M1
Barak, Y; Baratz-Goldstein, R; Hostovsky, A; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I1
Bergqvist, F; Demirbugen, M; Dunnett, SB; Lane, EL; Lindgren, HS1
Preskorn, SH1
Ago, Y; Hasebe, S; Hashimoto, H; Matsuda, T; Nishiyama, S; Oka, S; Takuma, K1
Dallé, E; Daniels, WM; Mabandla, MV1
Daws, LC; Koek, W; Sandoval, TL1
Matsumoto, M; Niwa, T; Shizuku, M; Yanai, M1
Chierrito, D; Fernandez-Llimos, F; Sanches, ACC; Tonin, FS; Villas-Boas, CB1

Reviews

6 review(s) available for desipramine and fluvoxamine

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The emergence of suicidal ideation and behavior during antidepressant pharmacotherapy.
    Archives of general psychiatry, 1991, Volume: 48, Issue:11

    Topics: Antidepressive Agents; Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Fluvoxamine; Humans; Imipramine; Mianserin; Suicide

1991
The pharmacotherapy of obsessive-compulsive disorder.
    Pharmacopsychiatry, 1993, Volume: 26 Suppl 1

    Topics: 1-Naphthylamine; Buspirone; Clomipramine; Desipramine; Fluoxetine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Sertraline

1993
Clinical psychopharmacology and medical malpractice: the four Ds.
    Journal of psychiatric practice, 2014, Volume: 20, Issue:5

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Depressive Disorder; Desipramine; Fatal Outcome; Female; Fluvoxamine; Forensic Psychiatry; Humans; Imipramine; Male; Malpractice; Mental Disorders; Psychopharmacology; Schizophrenia; Thioridazine

2014
Pharmacological treatment of attention-deficit hyperactivity disorder comorbid with an anxiety disorder: a systematic review.
    International clinical psychopharmacology, 2019, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Anxiety Disorders; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Central Nervous System Agents; Child; Comorbidity; Desipramine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Methylphenidate; Randomized Controlled Trials as Topic; Treatment Outcome

2019

Trials

11 trial(s) available for desipramine and fluvoxamine

ArticleYear
[Central analgesic effects of antidepressant drugs with various mechanisms of action: desipramine, fluvoxamine and moclobemide].
    Schweizerische medizinische Wochenschrift, 1991, Dec-07, Volume: 121, Issue:49

    Topics: Analgesics; Antidepressive Agents; Benzamides; Desipramine; Double-Blind Method; Electric Stimulation; Fluvoxamine; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Pain; Sural Nerve

1991
Fluvoxamine versus desipramine: comparative polysomnographic effects.
    Biological psychiatry, 1991, Jan-01, Volume: 29, Issue:1

    Topics: Adult; Antidepressive Agents; Arousal; Delta Rhythm; Depressive Disorder; Desipramine; Double-Blind Method; Electroencephalography; Female; Fluvoxamine; Humans; Male; Middle Aged; Oximes; Signal Processing, Computer-Assisted; Sleep, REM

1991
Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine.
    Archives of general psychiatry, 1990, Volume: 47, Issue:6

    Topics: Adult; Anxiety Disorders; Basal Ganglia; Depressive Disorder; Desipramine; Dopamine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Oximes; Panic; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1990
The role of neuropharmacologic selectivity in antidepressant action: fluvoxamine versus desipramine.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:9

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Norepinephrine; Oximes; Personality Inventory; Psychiatric Status Rating Scales; Serotonin; Serotonin Antagonists

1990
Fluvoxamine in the treatment of tricyclic-resistant depression.
    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa, 1990, Volume: 15, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Middle Aged; Oximes; Psychiatric Status Rating Scales; Serotonin Antagonists

1990
A double-blind comparison of fluvoxamine, desipramine and placebo in outpatients with depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:6

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Desipramine; Double-Blind Method; Fluvoxamine; Humans; Outpatients; Oximes; Placebos; Psychiatric Status Rating Scales; Random Allocation

1990
Effects of desipramine and fluvoxamine treatment on the prolactin response to tryptophan. Serotonergic function and the mechanism of antidepressant action.
    Archives of general psychiatry, 1989, Volume: 46, Issue:7

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Fluvoxamine; Humans; Oximes; Prolactin; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan

1989
Comparison of the effects of acute fluvoxamine and desipramine administration on melatonin and cortisol production in humans.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:2

    Topics: Adult; Analysis of Variance; Desipramine; Fluvoxamine; Humans; Hydrocortisone; Male; Melatonin; Radioimmunoassay

1994
An open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:7

    Topics: Adult; Ambulatory Care; Buspirone; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors

1993
Central analgesic effects of desipramine, fluvoxamine, and moclobemide after single oral dosing: a study in healthy volunteers.
    Clinical pharmacology and therapeutics, 1993, Volume: 54, Issue:3

    Topics: Administration, Oral; Adult; Analgesics; Analysis of Variance; Benzamides; Desipramine; Double-Blind Method; Fluvoxamine; Humans; Male; Moclobemide; Reference Values

1993
Addition of desipramine to serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder.
    The American journal of psychiatry, 1997, Volume: 154, Issue:9

    Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Adult; Clomipramine; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

1997

Other Studies

59 other study(ies) available for desipramine and fluvoxamine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography.
    Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6

    Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Female; HeLa Cells; Humans; Iodine Radioisotopes; Isotope Labeling; Ligands; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2003
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Effects of anxiolytic and antidepressant drugs on long-lasting behavioural deficits resulting from one short stress experience in male rats.
    Psychopharmacology, 1992, Volume: 109, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Desipramine; Diazepam; Electroshock; Fluvoxamine; Male; Motor Activity; Noise; Piperazines; Rats; Rats, Wistar; Serotonin Receptor Agonists; Stress, Psychological

1992
Dopamine and melatonin in the nucleus accumbens may be implicated in the mode of action of antidepressant drugs.
    European journal of pharmacology, 1992, Jun-24, Volume: 217, Issue:1

    Topics: Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluvoxamine; Male; Melatonin; Mianserin; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Dopamine; Sensitivity and Specificity

1992
Interaction between fluvoxamine and imipramine/desipramine in four patients.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:3

    Topics: Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged

1992
Interaction between antidepressants and d-amphetamine on variable-interval performance.
    Psychopharmacology, 1990, Volume: 100, Issue:4

    Topics: Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Fluvoxamine; Imipramine; Oximes; Psychomotor Performance; Rats; Rats, Inbred Strains; Reinforcement Schedule; Serotonin Antagonists; Trazodone

1990
Evolution of red blood cell membrane transport and plasma level of L-tyrosine and L-tryptophan in depressed treated patients according to clinical improvement.
    Neuropsychobiology, 1988, Volume: 19, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocyte Membrane; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Psychological Tests; Tryptophan; Tyrosine

1988
Interactions of 5HT reuptake inhibitors and ethanol in tests of exploration and anxiety.
    Advances in alcohol & substance abuse, 1988, Volume: 7, Issue:3-4

    Topics: Animals; Anxiety; Citalopram; Desipramine; Drug Interactions; Ethanol; Exploratory Behavior; Fluoxetine; Fluvoxamine; Mice; Mice, Inbred Strains; Motor Activity; Oximes; Serotonin Antagonists

1988
Behavioral interactions of fluoxetine and other 5-hydroxytryptamine uptake inhibitors with ethanol in tests of anxiety, locomotion and exploration.
    Psychopharmacology, 1988, Volume: 96, Issue:4

    Topics: Animals; Anxiety; Citalopram; Desipramine; Ethanol; Exploratory Behavior; Fluoxetine; Fluvoxamine; Male; Mice; Motor Activity; Oximes; Serotonin Antagonists

1988
The antidepressant agents desipramine, fluoxetine, fluvoxamine and norzimelidine inhibit uptake of [3H]noradrenaline and [3H]5-hydroxytryptamine in slices of human and rat cortical brain tissue.
    Brain research, 1983, Sep-19, Volume: 275, Issue:1

    Topics: Absorption; Animals; Antidepressive Agents; Cerebral Cortex; Desipramine; Fluoxetine; Fluvoxamine; Humans; In Vitro Techniques; Male; Norepinephrine; Oximes; Rats; Serotonin; Zimeldine

1983
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
    Neuropsychobiology, 1984, Volume: 12, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fluvoxamine; Imipramine; Male; Maprotiline; Mianserin; Oximes; Rats; Rats, Inbred Strains; Seizures; Viloxazine

1984
Neither the 5-HT1A- nor the 5-HT2-receptor subtype mediates the effect of fluvoxamine, a selective serotonin reuptake inhibitor, on forced-swimming-induced immobility in mice.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Desipramine; Disease Models, Animal; Drug Interactions; Fluvoxamine; Male; Mice; Mice, Inbred ICR; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin Antagonists

1995
Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:2

    Topics: Alprazolam; Biotransformation; Culture Techniques; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Dose-Response Relationship, Drug; Fluvoxamine; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors

1995
Compulsive exhibitionism successfully treated with fluvoxamine: a controlled case study.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:3

    Topics: Adult; Desipramine; Exhibitionism; Fluvoxamine; Humans; Male; Masturbation; Obsessive-Compulsive Disorder; Placebos; Psychiatric Status Rating Scales; Single-Blind Method; Treatment Outcome

1994
Fluvoxamine-induced alterations in plasma concentrations of imipramine and desipramine in depressed patients.
    International journal of clinical pharmacology research, 1993, Volume: 13, Issue:3

    Topics: Adult; Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged

1993
Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:3

    Topics: Adult; Desipramine; Drug Interactions; Fluvoxamine; Humans; Imipramine; Male

1993
Differential effects of fluoxetine on isoprenaline-stimulated water intake in ethanol-treated rats: a role for beta-adrenoceptors.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: Analysis of Variance; Animals; Desipramine; Drinking; Drug Interactions; Ethanol; Fluoxetine; Fluvoxamine; Injections, Intraperitoneal; Isoproterenol; Male; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Zimeldine

1993
Effects of desipramine and fluvoxamine on timing behavior investigated with the fixed-interval peak procedure and the interval bisection task.
    Psychopharmacology, 1996, Volume: 125, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Conditioning, Operant; Desipramine; Female; Fluvoxamine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Time Factors

1996
In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cerebral Cortex; Citalopram; Clonidine; Desipramine; Fluoxetine; Fluvoxamine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters

1996
The effects of different monoaminergic antidepressants on the analgesia induced by spinal cord adrenal medullary transplants in the formalin test in rats.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Adrenal Medulla; Amitriptyline; Analgesia; Animals; Antidepressive Agents; Desipramine; Fluvoxamine; Formaldehyde; Male; Rats; Rats, Wistar; Spinal Cord

1997
Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 16, Issue:5

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Buspirone; Depressive Disorder; Desipramine; Drug Synergism; Female; Fluvoxamine; Humans; Male; Pindolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Trimipramine

1997
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
    European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3

    Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

1997
Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:6

    Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclohexanols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Fluoxetine; Fluvoxamine; Frozen Sections; Humans; Hydroxylation; Imipramine; In Vitro Techniques; Lethal Dose 50; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Venlafaxine Hydrochloride

1997
Inhibition of imipramine N-demethylation by fluvoxamine in Chinese young men.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:5

    Topics: Adult; Antidepressive Agents, Tricyclic; Area Under Curve; Desipramine; Drug Interactions; Fluvoxamine; Humans; Imipramine; Male; Selective Serotonin Reuptake Inhibitors

1996
Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-01, Volume: 19, Issue:23

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Carrier Proteins; Desipramine; Fluvoxamine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Paroxetine; Phenelzine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sertraline; Time Factors

1999
MAO-A and MAO-B activities in rat striatum, frontal cortex and liver are unaltered after long-term treatment with fluvoxamine and desipramine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:2

    Topics: Animals; Blood Platelets; Corpus Striatum; Desipramine; Fluvoxamine; Frontal Lobe; Humans; Isoenzymes; Liver; Male; Monoamine Oxidase; Rats; Rats, Sprague-Dawley

2000
Tissue-specific regulation of the peripheral benzodiazepine receptor by antidepressants and lithium.
    Neuropsychobiology, 2000, Volume: 42, Issue:3

    Topics: Animals; Antidepressive Agents; Antimanic Agents; Cerebral Cortex; Desipramine; Fluvoxamine; Lithium Carbonate; Male; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2000
Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine proliferation in hippocampus.
    Brain research, 2000, Nov-17, Volume: 883, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Cell Count; Dendrites; Desipramine; Fluoxetine; Fluvoxamine; Hippocampus; Male; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors

2000
Comparison of noradrenergic and serotonergic antidepressants in reducing immobility time in the tail suspension test.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Fluoxetine; Fluvoxamine; Male; Models, Animal; Nortriptyline; Rats; Rats, Inbred Strains; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission; Tail

2001
Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice.
    Journal of neurochemistry, 2003, Volume: 86, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Carrier Proteins; Desipramine; Dose-Response Relationship, Drug; Drug Administration Routes; Fluvoxamine; Heterozygote; Hippocampus; Homozygote; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters

2003
Effects of selective serotonin reuptake inhibitors on immobility time in the tail suspension test in streptozotocin-induced diabetic mice.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Desipramine; Diabetes Mellitus, Experimental; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Hindlimb Suspension; Male; Mice; Mice, Inbred ICR; Motor Activity; Selective Serotonin Reuptake Inhibitors

2003
'Compulsive' lever-pressing in rats is attenuated by the serotonin re-uptake inhibitors paroxetine and fluvoxamine but not by the tricyclic antidepressant desipramine or the anxiolytic diazepam.
    Behavioural pharmacology, 2004, Volume: 15, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Compulsive Behavior; Conditioning, Operant; Desipramine; Diazepam; Dose-Response Relationship, Drug; Extinction, Psychological; Fluvoxamine; Male; Paroxetine; Rats; Rats, Wistar; Reward; Selective Serotonin Reuptake Inhibitors

2004
Antidepressant-like effect of tramadol and its enantiomers in reserpinized mice: comparative study with desipramine, fluvoxamine, venlafaxine and opiates.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:3

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Blepharoptosis; Body Temperature; Cyclohexanols; Desipramine; Fluvoxamine; Levorphanol; Male; Methadone; Mice; Morphine; Narcotics; Reserpine; Stereoisomerism; Time Factors; Tramadol; Venlafaxine Hydrochloride

2004
Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain.
    The American journal of psychiatry, 2004, Volume: 161, Issue:11

    Topics: Adult; Aged; Animals; Antidepressive Agents; Arrestins; beta-Arrestin 1; beta-Arrestins; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Depressive Disorder; Desipramine; Down-Regulation; Female; Fluvoxamine; Hippocampus; Humans; Imipramine; Leukocytes, Mononuclear; Male; Middle Aged; Psychiatric Status Rating Scales; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Severity of Illness Index

2004
Fluvoxamine and desipramine on fixed-ratio responding: effects of reinforcement magnitude.
    Behavioural pharmacology, 2005, Volume: 16, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Animals; Columbidae; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Fluvoxamine; Food; Reinforcement Schedule; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors

2005
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
    Psychopharmacology, 2007, Volume: 190, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Indophenol; Levorphanol; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Stereotyped Behavior; Tics; Tourette Syndrome; Tramadol; Triazoles

2007
Reinforcement magnitude modulates the rate-dependent effects of fluvoxamine and desipramine on fixed-interval responding in the pigeon.
    Behavioural pharmacology, 2008, Volume: 19, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Columbidae; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Fluvoxamine; Food; Male; Reinforcement Schedule; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors

2008
Mouse strain differences in immobility and sensitivity to fluvoxamine and desipramine in the forced swimming test: analysis of serotonin and noradrenaline transporter binding.
    European journal of pharmacology, 2008, Sep-11, Volume: 592, Issue:1-3

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Swimming

2008
Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons.
    Neuropharmacology, 2008, Volume: 55, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Blotting, Western; Cell Nucleus; Cytosol; Desipramine; Fibroblast Growth Factor 2; Fluvoxamine; Immunohistochemistry; Isomerism; Male; Neurons; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; Selective Serotonin Reuptake Inhibitors

2008
Reinforcement magnitude modulation of rate-dependent effects of fluvoxamine and desipramine in the rat.
    Behavioural pharmacology, 2008, Volume: 19, Issue:8

    Topics: Animals; Antidepressive Agents; Conditioning, Operant; Desipramine; Feeding Behavior; Fluvoxamine; Male; Rats; Rats, Inbred Lew; Regression Analysis; Reinforcement Schedule; Reinforcement, Psychology

2008
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
    Behavioural brain research, 2009, Aug-12, Volume: 201, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Ischemia; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluvoxamine; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Milnacipran; Motor Activity; Rats; Rats, Wistar

2009
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
    Neuroscience research, 2009, Volume: 64, Issue:3

    Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger

2009
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:10

    Topics: Animals; Antidepressive Agents; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bupropion; Desipramine; Diazepam; Dopamine Uptake Inhibitors; Fluvoxamine; Haloperidol; Imipramine; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology

2011
Automated experimental system capturing three behavioral components during murine forced swim test.
    Life sciences, 2011, Feb-28, Volume: 88, Issue:9-10

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Bupropion; Desipramine; Equipment Design; Fluvoxamine; Image Interpretation, Computer-Assisted; Imipramine; Male; Mice; Mice, Inbred Strains; Pattern Recognition, Automated; Psychomotor Performance; Swimming; Video Recording

2011
Interaction of different antidepressants with acute and chronic methadone in mice, and possible clinical implications.
    Journal of molecular neuroscience : MN, 2014, Volume: 52, Issue:4

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Citalopram; Clomipramine; Cyclohexanols; Desipramine; Drug Interactions; Fluvoxamine; Male; Methadone; Mice; Mice, Inbred ICR; Morpholines; Nociception; Pain Threshold; Reboxetine; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride

2014
The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions.
    Experimental neurology, 2014, Volume: 253

    Topics: Adrenergic Uptake Inhibitors; Animals; Brain Injuries; Cell Count; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Female; Fluvoxamine; Functional Laterality; Movement; Nerve Fibers; Norepinephrine; Oxidopamine; Rats; Reaction Time; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase

2014
Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice.
    Behavioural pharmacology, 2015, Volume: 26, Issue:7 Spec No

    Topics: Animals; Animals, Outbred Strains; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Desipramine; Duloxetine Hydrochloride; Fluvoxamine; Hydroxycorticosteroids; Idazoxan; Indoles; Male; Mice; Motor Activity; Neuropsychological Tests; Oxazines; Paroxetine; Piperazines; Psychotropic Drugs; Pyridines; Risperidone; Ritanserin; Social Behavior; Social Isolation; Sulfonamides; Venlafaxine Hydrochloride

2015
Fluvoxamine maleate normalizes striatal neuronal inflammatory cytokine activity in a Parkinsonian rat model associated with depression.
    Behavioural brain research, 2017, 01-01, Volume: 316

    Topics: Age Factors; Animals; Animals, Newborn; Anti-Anxiety Agents; Corpus Striatum; Cytokines; Depression; Desipramine; Disease Models, Animal; Fluvoxamine; Functional Laterality; Lipid Peroxidation; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Psychomotor Performance; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sucrose

2017
Effects of the antidepressants desipramine and fluvoxamine on latency to immobility and duration of immobility in the forced swim test in adult male C57BL/6J mice.
    Behavioural pharmacology, 2018, Volume: 29, Issue:5

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Desipramine; Disease Models, Animal; Fluoxetine; Fluvoxamine; Immobilization; Male; Mice; Mice, Inbred C57BL; Motor Activity; Swimming

2018
Effect of Cytochrome P450 (CYP) 2D6 Genetic Polymorphism on the Inhibitory Action of Antidepressants on CYP2D6-Mediated Dopamine Formation from p-Tyramine.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2018, Volume: 21, Issue:1

    Topics: Antidepressive Agents; Brain; Cytochrome P-450 CYP2D6; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluvoxamine; Humans; Imipramine; Polymorphism, Genetic; Structure-Activity Relationship; Tyramine

2018