desipramine and fluphenazine

desipramine has been researched along with fluphenazine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199013 (54.17)18.7374
1990's2 (8.33)18.2507
2000's4 (16.67)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Strassburg, CP; Tukey, RH1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Bleich, S; Kornhuber, J; Rupprecht, R; Terfloth, L; Wiltfang, J1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Modestin, J; Petrin, A1
Andrée, G; Meiser, H; Schmitt, W1
Klimek, V; Maj, J; Rawlów, A; Sarnek, J1
Henry, BW; Overall, JE; Woodward, JA1
Cervo, L; Grignaschi, G; Samanin, R1
Adan, F; Casey, E; Cooper, TB; Lee, A; Mandeli, J; Siris, SG1
Frisk-Holmberg, M; van der Kleijn, E1
Blacker, KH; Donlon, PT1
Garriott, JC; Stolman, A1
Núnek, K1
Burchinsky, SG1
Schechter, MD1
Jones, RS; Olpe, HR1
Bartone, P; Carter, M; Cooley, S; DiBarry, AL; Hammill, K; Hogarty, GE; McEvoy, JP; Munetz, MR; Perel, J; Ulrich, RF1
Gowda, R; Kuzu, OF; Noory, MA; Robertson, GP1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Reviews

4 review(s) available for desipramine and fluphenazine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine

1976
Neurotransmitter receptors in the central nervous system and aging: pharmacological aspect (review).
    Experimental gerontology, 1984, Volume: 19, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Brain; Desipramine; Dopamine; Dopamine Antagonists; Female; Fluphenazine; Haloperidol; Humans; Male; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Reserpine; Scopolamine; Spiperone; Tetrahydronaphthalenes; Tissue Distribution; Tritium

1984

Trials

1 trial(s) available for desipramine and fluphenazine

ArticleYear
Pharmacotherapy of impaired affect in recovering schizophrenic patients.
    Archives of general psychiatry, 1995, Volume: 52, Issue:1

    Topics: Adolescent; Adult; Ambulatory Care; Antipsychotic Agents; Anxiety Disorders; Basal Ganglia Diseases; Benztropine; Depressive Disorder; Desipramine; Diagnosis, Differential; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fluphenazine; Glycopyrrolate; Humans; Lithium Carbonate; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Sex Factors

1995

Other Studies

19 other study(ies) available for desipramine and fluphenazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Binding Sites; Computer Simulation; Databases, Factual; Models, Chemical; Models, Molecular; Molecular Structure; Molecular Weight; Psychotropic Drugs; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Psychotropic drugs and glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1976, Volume: 168, Issue:05

    Topics: Adult; Aged; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Female; Fluphenazine; Glaucoma; Humans; Imipramine; Intraocular Pressure; Male; Middle Aged; Opipramol; Perazine; Psychotropic Drugs; Thiothixene; Tonometry, Ocular

1976
On the anticataleptic action of cyproheptadine.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone

1976
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
    Diseases of the nervous system, 1975, Volume: 36, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine

1975
The role of the mesolimbic dopaminergic system in the desipramine effect in the forced swimming test.
    European journal of pharmacology, 1990, Mar-13, Volume: 178, Issue:1

    Topics: Animals; Depression; Desipramine; Dopamine; Fluphenazine; Hydroxydopamines; Injections; Limbic System; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Swimming; Synapses; Synaptic Transmission

1990
Patterns of plasma imipramine-desipramine concentrations in patients receiving concomitant fluphenazine decanoate.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:2

    Topics: Adult; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Fluphenazine; Humans; Hydroxylation; Imipramine; Male; Middle Aged; Psychotic Disorders; Schizophrenia

1988
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
Stages of schizophrenic decompensation and reintegration.
    The Journal of nervous and mental disease, 1973, Volume: 157, Issue:3

    Topics: Adult; Affect; Aggression; Antipsychotic Agents; Anxiety; Depression; Desipramine; Fear; Female; Fluphenazine; Hostility; Humans; Male; Middle Aged; Schizophrenia; Thioridazine; Trifluoperazine

1973
Detection of some psychotherapeutic drugs and their metabolites in urine.
    Clinical toxicology, 1971, Volume: 4, Issue:2

    Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine

1971
[Current problems of endogenous depression].
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine

1970
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine

1980
An increase in sensitivity of rat cingulate cortical neurones to substance P occurs following withdrawal of chronic administration of antidepressant drugs.
    British journal of pharmacology, 1984, Volume: 81, Issue:4

    Topics: Action Potentials; Animals; Antidepressive Agents; Clomipramine; Desipramine; Diazepam; Drug Resistance; Fluphenazine; Gyrus Cinguli; Male; Neurons; Rats; Substance P; Time Factors; Trimipramine; Zimeldine

1984
Modulating cancer cell survival by targeting intracellular cholesterol transport.
    British journal of cancer, 2017, Aug-08, Volume: 117, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Autophagy; bcl-2-Associated X Protein; Biological Transport; Cell Survival; Cholesterol; Desipramine; Endocytosis; Endosomes; Female; Flupenthixol; Fluphenazine; Gene Expression Regulation; Gene Knockdown Techniques; HCT116 Cells; Homeostasis; Humans; Inhibitory Concentration 50; Liposomes; Lysosomes; MCF-7 Cells; Melanoma; Mice; Nortriptyline; Perphenazine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingomyelin Phosphodiesterase; STAT3 Transcription Factor

2017
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013