desipramine and dsp 4

desipramine has been researched along with dsp 4 in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199022 (55.00)18.7374
1990's11 (27.50)18.2507
2000's5 (12.50)29.6817
2010's2 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blohm, M; Bönisch, H; Fink, K; Göthert, M; Molderings, G1
de Boer, T; Hagan, JJ; Jansen, JH; Nefkens, FE1
Campbell, IC; Ellison, DW1
Iuvone, PM; Johnson, RD; Minneman, KP1
Arbilla, S; Benkirane, S; Langer, SZ1
De Herdt, P; Jones, RS; Laszlo, J; Olpe, HR; Pozza, MF; Waldmeier, PC1
Jacobson, W; Wilkinson, DA; Wilkinson, M1
Swann, AC2
Archer, T; Fredriksson, A; Jonsson, G; Lewander, T; Mohammed, AK; Ross, SB; Söderberg, U1
Esposito, E; Mennini, T; Merlo-Pich, E; Romandini, S; Samanin, R1
Esposito, E; Ossowska, G; Samanin, R1
Hallman, H; Jonsson, G1
Archer, T; Cotic, T; Järbe, TU1
Hall, H; Ross, SB; Sällemark, M1
Anisman, H; Beauchamp, C; Bruto, V; Zacharko, RM1
Berge, OG; Ogren, SO1
Archer, T; Johansson, C; Ogren, SO1
Archer, T; Jonsson, G; Ross, SB1
Archer, T; Johansson, G; Ogren, SO; Ross, SB1
Archer, T1
Hallman, H; Jonsson, G; Sundström, E1
Jaim-Etcheverry, G; Zieher, LM1
Archer, T; Ogren, SO; Ross, SB1
Burt, AM; Gillespie, DD; Huang, M; Nalepa, I; Perrin, C; Rossby, SP; Schmidt, DE; Sulser, F1
Matsumoto, K; Ojima, K; Watanabe, H1
Boulton, AA; Davis, BA; Fang, J; Yu, PH1
Cooper, RL; Goldman, JM; McElroy, WK; Parrish, MB; Stoker, TE1
Hughes, ZA; Stanford, SC3
Commissaris, RL; Fontana, DJ; McMiller, LV1
Allikmets, L; Matto, V; Skrebuhhova, T1
Harkin, A; Nowak, G; Paul, IA1
Harkin, A; Kelly, JP; Leonard, BE; Morris, K; O'Donnell, JM1
Fujiwara, M; Hatip-Al-Khatib, I; Iwasaki, K; Mishima, K1
Pericić, D; Svob, D1
Bechtholt, AJ; Crowley, JJ; Lucki, I; O'Leary, OF; Valentino, RJ1
Kompagne, H; Kuki, Z; Lévay, G; Markó, B; Nagy, KM; Sziray, N1
Berrocoso, E; Bravo, L; Camarena-Delgado, C; Mico, JA; Rey-Brea, R1

Other Studies

40 other study(ies) available for desipramine and dsp 4

ArticleYear
Preferential location of N-methyl-D-aspartate (NMDA) receptors on postsynaptic membranes and on non-noradrenergic nerve terminals of the rat brain cortex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:6

    Topics: Animals; Benzylamines; Brain; Cell Membrane; Desipramine; Male; Nerve Endings; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Sympathomimetics

1992
Therapeutic effect of THA on hemicholinium-3-induced learning impairment is independent of serotonergic and noradrenergic systems.
    Psychopharmacology, 1990, Volume: 101, Issue:3

    Topics: 5,7-Dihydroxytryptamine; Aminoacridines; Animals; Benzylamines; Desipramine; Discrimination, Psychological; Hemicholinium 3; Injections, Intraventricular; Learning Disabilities; Male; Norepinephrine; Rats; Serotonin; Space Perception; Tacrine

1990
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine

1986
Regulation of alpha-1 adrenergic receptor density and functional responsiveness in rat brain.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Animals; Benzylamines; Brain Chemistry; Cyclic AMP; Desipramine; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine; Yohimbine

1987
Supersensitivity of alpha 2-adrenoceptors modulating [3H]5-HT release after noradrenergic denervation with DSP4.
    European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Amines; Animals; Benzylamines; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Hippocampus; Idazoxan; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Serotonin; Sympathectomy, Chemical

1985
Glutamate-induced activation of rat locus coeruleus increases CA1 pyramidal cell excitability.
    Neuroscience letters, 1986, Mar-28, Volume: 65, Issue:1

    Topics: Animals; Benzylamines; Brain Mapping; Desipramine; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Locus Coeruleus; Male; Neural Pathways; Norepinephrine; Rats; Synaptic Transmission

1986
The noradrenergic neurotoxins DSP4 and xylamine bind to opiate receptors.
    Brain research bulletin, 1985, Volume: 14, Issue:5

    Topics: Amines; Animals; Benzylamines; Binding, Competitive; Cerebral Cortex; Cocaine; Desipramine; Female; In Vitro Techniques; Male; Naloxone; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid

1985
(Na+,K+)-ATPase and noradrenergic regulation: effects of cardiac glycoside treatment and noradrenergic manipulations.
    European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2

    Topics: Animals; Benzylamines; Brain; Cardiac Glycosides; Clonidine; Desipramine; Digitoxin; Dihydroalprenolol; Kidney; Male; Methoxyhydroxyphenylglycol; Myocardium; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase; Yohimbine

1985
(Na+,K+)-ATPase and noradrenergic function: effects of chronic ethanol.
    European journal of pharmacology, 1987, Feb-10, Volume: 134, Issue:2

    Topics: Animals; Benzylamines; Desipramine; Ethanol; Heart; Male; Neurotoxins; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Yohimbine

1987
Central noradrenaline depletion antagonizes aspects of d-amphetamine-induced hyperactivity in the rat.
    Psychopharmacology, 1986, Volume: 88, Issue:2

    Topics: Animals; Benzylamines; Central Nervous System; Desipramine; Dextroamphetamine; Drug Interactions; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains

1986
Evidence of the involvement of dopamine in the analgesic effect of nefopam.
    European journal of pharmacology, 1986, Sep-09, Volume: 128, Issue:3

    Topics: 5,7-Dihydroxytryptamine; Analgesics; Animals; Benzylamines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Desipramine; Dopamine; Hydroxydopamines; Injections, Intraventricular; Male; Nefopam; Oxazocines; Oxidopamine; Rats; Reserpine

1986
Further evidence that noradrenaline is not involved in the anti-immobility activity of chronic desipramine in the rat.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Benzylamines; Brain Chemistry; Desipramine; Hydroxydopamines; Immobilization; Injections; Locus Coeruleus; Male; Motor Activity; Norepinephrine; Oxidopamine; Rats; Sympathectomy, Chemical

1987
Pharmacological modifications of the neurotoxic action of the noradrenaline neurotoxin DSP4 on central noradrenaline neurons.
    European journal of pharmacology, 1984, Aug-17, Volume: 103, Issue:3-4

    Topics: Amines; Animals; Benzylamines; Catecholamines; Central Nervous System; Desipramine; Female; In Vitro Techniques; Levodopa; Male; Neurons; Neurotransmitter Uptake Inhibitors; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Synaptosomes

1984
Attenuation of the context effect and lack of unconditioned stimulus-preexposure effect in taste-aversion learning following treatment with DSP4, the selective noradrenaline neurotoxin.
    Behavioral and neural biology, 1982, Volume: 35, Issue:2

    Topics: Amines; Animals; Association Learning; Avoidance Learning; Benzylamines; Chlorides; Conditioning, Classical; Cues; Desipramine; Dopamine beta-Hydroxylase; Frontal Lobe; Hippocampus; Lithium; Lithium Chloride; Male; Muscle Contraction; Neurotoxins; Norepinephrine; Rats; Rats, Inbred Strains; Reflex; Taste

1982
Effect of destruction of central noradrenergic and serotonergic nerve terminals by systemic neurotoxins on the long-term effects of antidepressants on beta-adrenoceptors and 5-HT2 binding sites in the rat cerebral cortex.
    Journal of neural transmission, 1984, Volume: 59, Issue:1

    Topics: Alanine; Amines; Animals; Antidepressive Agents; Benzylamines; Binding Sites; Cerebral Cortex; Clenbuterol; Desipramine; Dihydroalprenolol; Male; Mianserin; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Spiperone; Zimeldine

1984
Amphetamine-induced perseverative behavior in a radial arm maze following DSP4 or 6-OHDA pretreatment.
    Psychopharmacology, 1984, Volume: 83, Issue:1

    Topics: Amines; Animals; Behavior, Animal; Benzylamines; Brain Chemistry; Desipramine; Dextroamphetamine; Dopamine; Hydroxydopamines; Male; Mice; Norepinephrine; Oxidopamine

1984
Limited involvement of central noradrenergic pathways in morphine-induced antinociception.
    Neuropharmacology, 1984, Volume: 23, Issue:10

    Topics: Animals; Benzylamines; Desipramine; Drug Interactions; Male; Morphine; Nervous System; Norepinephrine; Pain; Rats; Rats, Inbred Strains

1984
Evidence for a selective brain noradrenergic involvement in the locomotor stimulant effects of amphetamine in the rat.
    Neuroscience letters, 1983, Dec-30, Volume: 43, Issue:2-3

    Topics: Animals; Benzylamines; Brain; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Humans; Male; Motor Activity; Norepinephrine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Stimulation, Chemical

1983
A parametric study of the effects of the noradrenaline neurotoxin DSP4 on avoidance acquisition and noradrenaline neurones in the CNS of the rat.
    British journal of pharmacology, 1984, Volume: 82, Issue:1

    Topics: Amines; Animals; Avoidance Learning; Benzylamines; Brain; Brain Chemistry; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Time Factors

1984
DSP4-induced two-way active avoidance impairment in rats: involvement of central and not peripheral noradrenaline depletion.
    Psychopharmacology, 1982, Volume: 76, Issue:4

    Topics: Amines; Animals; Avoidance Learning; Benzylamines; Brain; Cerebellum; Cerebral Cortex; Desipramine; Escape Reaction; Hippocampus; Imipramine; Limbic System; Male; Motor Activity; Neurons; Neurotoxins; Norepinephrine; Peripheral Nerves; Rats; Rats, Inbred Strains

1982
DSP4 (N-2-chloroethyl-N-ethyl-2-bromobenzylamine), a new noradrenaline neurotoxin, and stimulus conditions affecting acquisition of two-way active avoidance.
    Journal of comparative and physiological psychology, 1982, Volume: 96, Issue:3

    Topics: Amines; Animals; Attention; Avoidance Learning; Benzylamines; Brain; Conditioning, Classical; Desipramine; Dopamine; Electroshock; Fear; Male; Neurotoxins; Norepinephrine; Rats; Rats, Inbred Strains; Retention, Psychology; Serotonin

1982
Effects of the noradrenaline neurotoxin DSP4 on the postnatal development of central noradrenaline neurons in the rat.
    Neuroscience, 1982, Volume: 7, Issue:11

    Topics: Amines; Animals; Benzylamines; Central Nervous System; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Neurotoxins; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Serotonin

1982
Neurotoxicity of N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride (DSP 4) on noradrenergic neurons is mimicked by its cyclic aziridinium derivative.
    European journal of pharmacology, 1980, Jul-25, Volume: 65, Issue:2-3

    Topics: Amines; Animals; Benzylamines; Brain Chemistry; Desipramine; Female; Injections, Intraventricular; Mice; Myocardium; Nervous System Diseases; Neurons; Norepinephrine; Sympathetic Nervous System; Time Factors

1980
Evidence for a role of the locus coeruleus noradrenaline system in learning.
    Neuroscience letters, 1980, Volume: 20, Issue:3

    Topics: Amines; Animals; Avoidance Learning; Benzylamines; Brain Chemistry; Desipramine; Dopamine; Locus Coeruleus; Male; Norepinephrine; Rats; Serotonin; Spinal Cord

1980
Norepinephrine-independent regulation of GRII mRNA in vivo by a tricyclic antidepressant.
    Brain research, 1995, Jul-31, Volume: 687, Issue:1-2

    Topics: Animals; Antidepressive Agents, Tricyclic; Benzylamines; Biogenic Monoamines; Desipramine; Fluoxetine; Hippocampus; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Sympathomimetics

1995
Noradrenergic denervation attenuates desipramine enhancement of aggressive behavior in isolated mice.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:3

    Topics: Aggression; Animals; Benzylamines; Brain; Denervation; Desipramine; Male; Mice; Mice, Inbred Strains; Neurotoxins; Norepinephrine; Social Isolation

1995
Neuroprotective effects of some monoamine oxidase-B inhibitors against DSP-4-induced noradrenaline depletion in the mouse hippocampus.
    Journal of neurochemistry, 1994, Volume: 63, Issue:5

    Topics: Animals; Benzylamines; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Male; Mice; Monoamine Oxidase Inhibitors; Neurons; Neurotransmitter Uptake Inhibitors; Norepinephrine; Pargyline; Phenelzine; Propylamines; Selegiline; Time Factors

1994
Suppression of oocyte release in rats by local administration of the noradrenergic neurotoxin DSP4.
    Journal of reproduction and fertility, 1996, Volume: 106, Issue:2

    Topics: Adrenergic Agents; Animals; Benzylamines; Desipramine; Dose-Response Relationship, Drug; Female; Naloxone; Narcotic Antagonists; Neurotoxins; Norepinephrine; Ovary; Ovulation; Rats; Rats, Inbred Strains

1996
Increased noradrenaline efflux induced by local infusion of fluoxetine in the rat frontal cortex.
    European journal of pharmacology, 1996, Dec-12, Volume: 317, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Benzylamines; Citalopram; Desipramine; Fluoxetine; Frontal Lobe; In Vitro Techniques; Injections; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Synaptosomes

1996
A partial noradrenergic lesion induced by DSP-4 increases extracellular noradrenaline concentration in rat frontal cortex: a microdialysis study in vivo.
    Psychopharmacology, 1998, Volume: 136, Issue:3

    Topics: Animals; Benzylamines; Biogenic Monoamines; Calcium; Desipramine; Extracellular Space; Male; Microdialysis; Neurotransmitter Uptake Inhibitors; Norepinephrine; Potassium; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Sympathomimetics

1998
Evidence from microdialysis and synaptosomal studies of rat cortex for noradrenaline uptake sites with different sensitivities to SSRIs.
    British journal of pharmacology, 1998, Volume: 124, Issue:6

    Topics: 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents, Tricyclic; Benzylamines; Citalopram; Desipramine; Fluoxetine; Frontal Lobe; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Synaptosomes

1998
Depletion of brain norepinephrine: differential influence on anxiolyic treatment effects.
    Psychopharmacology, 1999, Volume: 143, Issue:2

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzylamines; Biogenic Monoamines; Brain Chemistry; Conflict, Psychological; Desipramine; Dose-Response Relationship, Drug; Female; Hypnotics and Sedatives; Monoamine Oxidase Inhibitors; Norepinephrine; Phenelzine; Phenobarbital; Rats; Rats, Sprague-Dawley; Sympathomimetics

1999
[3H]-ketanserin binding and elevated plus-maze behavior after chronic antidepressant treatment in DSP-4 and P-CPA pretreated rats: evidence for partial involvement of 5-HT2A receptors.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:7

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzylamines; Binding Sites; Citalopram; Desipramine; Fenclonine; Ketanserin; Kinetics; Male; Maze Learning; Neurotransmitter Uptake Inhibitors; Protein Binding; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Tritium

1999
Noradrenergic lesion antagonizes desipramine-induced adaptation of NMDA receptors.
    European journal of pharmacology, 2000, Feb-18, Volume: 389, Issue:2-3

    Topics: Adaptation, Physiological; Animals; Antidepressive Agents, Tricyclic; Benzylamines; Cerebral Cortex; Desipramine; Fluoxetine; Glycine; Kynurenic Acid; Male; Mice; Norepinephrine; Receptors, N-Methyl-D-Aspartate

2000
Modulation of MK-801-induced behaviour by noradrenergic agents in mice.
    Psychopharmacology, 2001, Mar-01, Volume: 154, Issue:2

    Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Ataxia; Benzylamines; Clonidine; Desipramine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Frontal Lobe; Male; Mesencephalon; Mice; Morpholines; Motor Activity; Norepinephrine; Prazosin; Reboxetine; Stereotyped Behavior

2001
Microdialysates of amines and metabolites from core nucleus accumbens of freely moving rats are altered by dizocilpine.
    Brain research, 2001, May-25, Volume: 902, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Chromatography, High Pressure Liquid; Desipramine; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Reserpine; Serotonin

2001
Interaction of stress and noradrenergic drugs in the control of picrotoxin-induced seizures.
    Epilepsy research, 2002, Volume: 51, Issue:1-2

    Topics: Adrenergic Agents; Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Analysis of Variance; Animals; Benzylamines; Desipramine; Drug Interactions; Enzyme Inhibitors; GABA Antagonists; Male; Mice; Mice, Inbred CBA; Picrotoxin; Seizures; Stress, Physiological; Swimming

2002
The role of noradrenergic tone in the dorsal raphe nucleus of the mouse in the acute behavioral effects of antidepressant drugs.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Benzylamines; Cerebral Cortex; Citalopram; Desipramine; Dopamine beta-Hydroxylase; Fluoxetine; Hindlimb Suspension; Immunohistochemistry; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Norepinephrine; Oxidopamine; Presynaptic Terminals; Raphe Nuclei; Selective Serotonin Reuptake Inhibitors

2007
Effects of single and simultaneous lesions of serotonergic and noradrenergic pathways on open-space and bright-space anxiety-like behavior in two animal models.
    Behavioural brain research, 2010, May-01, Volume: 209, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Adaptation, Physiological; Adrenergic Agents; Adrenergic Uptake Inhibitors; Animals; Anxiety; Benzylamines; Chromatography, High Pressure Liquid; Desipramine; Disease Models, Animal; Exploratory Behavior; Fluoxetine; Injections, Intraventricular; Male; Maze Learning; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Spatial Behavior

2010
Effect of DSP4 and desipramine in the sensorial and affective component of neuropathic pain in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 10-03, Volume: 70

    Topics: Adrenergic Agents; Adrenergic Uptake Inhibitors; Analgesics; Animals; Antidepressive Agents; Avoidance Learning; Axons; Benzylamines; Desipramine; Disease Models, Animal; Escape Reaction; Extracellular Signal-Regulated MAP Kinases; Gyrus Cinguli; Male; Neuralgia; Neurotransmitter Agents; Pain Threshold; Phosphorylation; Random Allocation; Rats, Sprague-Dawley

2016