desipramine has been researched along with corticosterone in 112 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (13.39) | 18.7374 |
| 1990's | 30 (26.79) | 18.2507 |
| 2000's | 39 (34.82) | 29.6817 |
| 2010's | 26 (23.21) | 24.3611 |
| 2020's | 2 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Gambaryan, S; Gorboulev, V; Gründemann, D; Koepsell, H; Veyhl, M | 1 |
| Giacomini, KM; Schaner, ME; Zhang, L | 1 |
| Chen, J; Conway, SJ; Fei, YJ; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wu, X | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Akhoundova, A; Arndt, P; Bamberg, E; Budiman, T; Gorboulev, V; Koepsell, H; Koppatz, S; Nagel, G; Popp, C; Ulzheimer-Teuber, I; Volk, C | 1 |
| Caron, G; Ermondi, G | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
| Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Akamatsu, M | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E | 1 |
| Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW | 1 |
| Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E | 1 |
| Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E | 1 |
| Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW | 1 |
| Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Alcaro, S; Bagetta, D; Borges, F; Cagide, F; Oliveira, PJ; Ortuso, F; Pérez, C; Reis, J; Rodríguez-Franco, MI; Teixeira, J; Uriarte, E; Valencia, ME | 1 |
| Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Keim, KL; Sigg, EB | 1 |
| Orrego, F; Sánchez-Armáss, S | 1 |
| Goshima, Y; Kuwahara, M; Matsushita, N; Misu, Y | 1 |
| Grealy, M; O'Donnell, JM | 2 |
| Malinowska, B; Molderings, G; Schlicker, E; Schneider, D | 1 |
| Marshall, IG; Prior, C; Wannan, G | 1 |
| Akiyoshi, J; Ito, Y; Kojima, K; Miyamoto, T; Nagayama, H; Oba, A; Okada, K; Tsuchiyama, K; Yamada, K; Yamauchi, C | 1 |
| Blöchl, A; Dominiak, P | 1 |
| Austin, CE; Chess-Williams, R; O'Brien, HL | 1 |
| Carton, EG; Cook, DJ; Housmans, PR | 1 |
| Carr, KD; Herrera, AS; McEwen, BS; Stone, EA | 1 |
| Göthert, M; Hentrich, F; Likungu, J; Molderings, GJ | 1 |
| Ohi, K; Shimoda, K; Takahashi, K; Takahashi, S; Tsujimoto, T; Yamada, N | 1 |
| Buder, M; Fuder, H; Riers, HD; Rothacher, G | 1 |
| Fukuda, S; Lee, TJ; Su, C | 1 |
| Brooks, WH; Cross, RJ; Jackson, JC; Markesbery, WR; Roszman, TL; Walker, RF | 1 |
| Brown, GM; Seggie, J | 1 |
| Gisler, RH | 1 |
| Rosecrans, JA | 1 |
| Agnati, LF; Andersson, K; Eneroth, P; Fuxe, K; Ogren, SO | 1 |
| Platt, JE; Stone, EA; Trullas, R | 1 |
| Chan, MY; Hung, F | 1 |
| Acosta, S; Au, D; Edelstein, M; Lutchmansingh, P; McCracken, JT; McGeoy, S; Poland, RE; Que, M | 1 |
| Muneoka, K; Nankai, M; Toru, M; Yamada, S | 1 |
| Dygalo, NN; Iushkova, AA; Shishkina, GT; Surnina, NIu | 1 |
| Dombrowski, MP; Hurd, WW; Leach, KC; Saraf, HA | 1 |
| Azevedo, I; Martel, F; Osswald, W | 1 |
| Kengatharan, M; Mackay, D | 1 |
| de la Lande, IS; Ivar, PM; Marino, V; Parker, DA; Parker, I; Proctor, CH | 1 |
| Kuroda, Y; Mikuni, M; Ogawa, T; Takahashi, K | 1 |
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Nedergaard, OA | 1 |
| Dunn, AJ; Stone, EA; Swiergiel, AH | 1 |
| Centeno, VA; Volosin, M | 1 |
| Martel, F | 1 |
| Connor, TJ; Kelly, JP; Leonard, BE | 1 |
| Armario, A; Gómez, F; Graugés, P; Martín, M | 1 |
| de la Lande, IS; Ivar, PM; Marino, V; Parker, DA | 1 |
| Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Brock, JA; Dunn, WR; Hardy, TA | 1 |
| Connor, TJ; Harkin, A; Kelly, JP; Leonard, BE | 1 |
| Connor, TJ; Harkin, A; Kelliher, P; Kelly, JP; Leonard, BE; Shen, Y | 1 |
| Baker, RA; Gold, PW; Makino, S; Smith, MA | 1 |
| Lomholt, M; Nedergaard, OA | 1 |
| Li, YF; Luo, ZP | 1 |
| Blendy, JA; Conti, AC; Cryan, JF; Dalvi, A; Lucki, I | 1 |
| Cao, L; Filipov, NM; Lawrence, DA | 1 |
| Gong, ZH; Li, YF; Luo, ZP; Yang, M; Zhao, YM | 1 |
| Hillard, CJ; Kalyanaraman, B; Shang, T; Uihlein, AV; Van Asten, J | 1 |
| Huang, WC; Li, YF; Liu, YQ; Luo, ZP | 1 |
| Kim, J; Lopez-Rodriguez, F; Poland, RE | 1 |
| Blendy, JA; Conti, AC; Kuo, YC; Valentino, RJ | 1 |
| Huang, WC; Li, YF; Liu, YQ; Luo, ZP; Wang, HL; Yang, M; Zhao, YM | 1 |
| Barden, N; Labbé, M; Mocaër, E; Rochford, J; Shink, E; Vacher, R | 1 |
| Dwivedi, Y; Pandey, GN; Rizavi, HS | 1 |
| Chen, H; Dwivedi, Y; Pandey, GN | 1 |
| Calil, CM; Marcondes, FK | 1 |
| Kerwin, R; Lightman, S; Morgan, PE; Noble, J; Pariante, CM; Seckl, JR; Thomas, S; Yau, JL | 1 |
| Bächli, H; Habersetzer, U; Steiner, MA; Wotjak, CT | 1 |
| Holsboer, F; Lutz, B; Marsicano, G; Nestler, EJ; Steiner, MA; Wotjak, CT | 1 |
| Lin, Y; Stone, EA | 1 |
| Lolait, SJ; O'Carroll, AM; Roper, JA; Stewart, LQ; Young, WS | 1 |
| Akil, H; Calvo, N; Cecchi, M; Jama, A; Watson, SJ | 1 |
| Bachis, A; Cruz, MI; Mocchetti, I; Nosheny, RL | 1 |
| Dow, A; Duman, RS; Hajszan, T; Leranth, C; Parducz, A; Sallam, NL; Szigeti-Buck, K; Warner-Schmidt, JL | 1 |
| Bayer, M; Bruchelt, G; Dittmann, H; Gründemann, D; Handgretinger, R; Kuçi, Z; Schömig, E | 1 |
| Besedovsky, HO; del Rey, A; Doenlen, R; Engler, A; Engler, H; Feldon, J; Niemi, MB; Pacheco-López, G; Riether, C; Schedlowski, M | 1 |
| Breese, G; Fredericks, K; Knapp, D; McMichael, J; Overstreet, DH | 1 |
| Feinstein, DL; Garcia-Bueno, B; Hinojosa, AE; Leza, JC; Madrigal, JL; Polak, P | 1 |
| Andrews, AM; Earnheart, JC; Lal, R; Luellen, BA; Luscher, B; Shen, Q | 1 |
| Lightman, SL; Mason, BL; Pariante, CM; Thomas, SA | 1 |
| Hetzenauer, A; Sartori, SB; Singewald, N; Whittle, N | 1 |
| Altimus, CM; Hattar, S; Kirkwood, A; Lee, HK; LeGates, TA; Wang, H; Weber, ET; Yang, S; Zhao, H | 1 |
| Glac, W; Grembecka, B; Kubera, M; Listowska, M; Majkutewicz, I; Plucińska, K; Podlacha, M; Wojtyła-Kuchta, B; Wrona, D | 1 |
| Chen, F; Liebenberg, N; Nava, N; Nyengaard, JR; Popoli, M; Treccani, G; Wegener, G | 1 |
| Bambico, FR; Comai, S; Dominguez-Lopez, S; Gobbi, G; Ochoa-Sanchez, R | 1 |
| Glac, W; Grembecka, B; Grzybowska, M; Listowska, M; Wrona, D | 1 |
| Alabsi, A; Elfving, B; Kaastrup Mueller, H; Nava, N; Nyengaard, JR; Popoli, M; Treccani, G; Wegener, G | 1 |
| Elfving, B; Müller, HK; Nava, N; Popoli, M; Treccani, G; Wegener, G | 1 |
| Liu, J; Peng, X; Qiu, M; Yan, H; Zhang, L; Zhang, R | 1 |
1 review(s) available for desipramine and corticosterone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
111 other study(ies) available for desipramine and corticosterone
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Drug excretion mediated by a new prototype of polyspecific transporter.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cations; Cells, Cultured; DNA, Complementary; Intestinal Mucosa; Kidney Tubules, Proximal; Liver; Membrane Proteins; Molecular Sequence Data; Organic Cation Transporter 1; Pharmacokinetics; Recombinant Proteins; RNA, Messenger; Xenopus | 1994 |
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection | 1998 |
Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biogenic Monoamines; Brain; Carrier Proteins; Cell Line; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Neurotoxins; Neurotransmitter Agents; Oocytes; Rats; Xenopus laevis | 1998 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
Topics: Animals; Anions; Carrier Proteins; Cations; Cell Line; Cell Membrane; Choline; Cloning, Molecular; Female; Guanidine; Histamine; Humans; In Vitro Techniques; Kidney; Kinetics; Membrane Potentials; Membrane Proteins; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Transfection; Xenopus laevis | 2001 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding | 2009 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding | 2014 |
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies | 2014 |
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins | 2014 |
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship | 2014 |
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi | 2015 |
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship | 2016 |
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2016 |
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species | 2017 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.
Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Chromones; Drug Design; Hep G2 Cells; Humans; Ligands; Molecular Docking Simulation; Molecular Targeted Therapy; Monoamine Oxidase; Monoamine Oxidase Inhibitors | 2018 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine | 2019 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
Plasma corticosterone and brain catecholamines in stress: effect of psychotropic drugs.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Corticosterone; Desipramine; Diazepam; Dopamine; Haloperidol; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Pargyline; Phenobarbital; Prohibitins; Psychotropic Drugs; Rats; Stress, Physiological; Telencephalon | 1977 |
Noradrenaline transport by rat heart sympathetic nerves: a re-examination of the role of sodium ions.
Topics: Animals; Biological Transport, Active; Chlorides; Corticosterone; Desipramine; Heart; In Vitro Techniques; Kinetics; Norepinephrine; Rats; Sodium; Sympathetic Nervous System | 1978 |
Effects of nanomolar to submillimolar carteolol on noradrenaline release in the absence and presence of uptake1 and uptake2 blockers in guinea pig pulmonary arteries.
Topics: Animals; Carteolol; Cocaine; Corticosterone; Desipramine; Drug Interactions; Guinea Pigs; In Vitro Techniques; Male; Microelectrodes; Norepinephrine; Normetanephrine; Pulmonary Artery | 1992 |
Neuroendocrine response to clonidine and 8-OH-DPAT in rats following chronic administration of desipramine or sertraline.
Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cerebral Cortex; Clonidine; Corticosterone; Desipramine; Dihydroalprenolol; Male; Neurosecretory Systems; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sertraline; Tetrahydronaphthalenes | 1992 |
Noradrenaline release in the rat vena cava is inhibited by gamma-aminobutyric acid via GABAB receptors but not affected by histamine.
Topics: Animals; Baclofen; Bicuculline; Corticosterone; Desipramine; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; In Vitro Techniques; Male; Muscimol; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vena Cava, Inferior; Yohimbine | 1991 |
Alpha-adrenoceptor blocking properties of vesamicol.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Vas Deferens | 1991 |
Corticosterone response to 8-OH-DPAT after chronic administration of antidepressants.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Corticosterone; Desipramine; Dose-Response Relationship, Drug; Doxepin; Male; Mianserin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1991 |
Does converting enzyme inhibition change the neuronal and extraneuronal uptake of catecholamines?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bridged Bicyclo Compounds; Catecholamines; Corticosterone; Desipramine; Epinephrine; Heart; Myocardium; Norepinephrine; Ramipril; Rats; Rats, Inbred SHR; Tubocurarine; Vagotomy | 1991 |
Secretion of growth hormone elicited by intravenous desipramine in the conscious, unrestrained rat.
Topics: Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Growth Hormone; Hypothalamo-Hypophyseal System; Idazoxan; Injections, Intravenous; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Alpha-adrenoceptors do not contribute to the chronotropic or inotropic responses of the avian heart to noradrenaline.
Topics: Animals; Chickens; Cocaine; Corticosterone; Desipramine; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Methoxamine; Myocardial Contraction; Norepinephrine; Phentolamine; Propranolol; Receptors, Adrenergic, alpha | 1991 |
Mechanism of the positive inotropic effect of ketamine in isolated ferret ventricular papillary muscle.
Topics: Animals; Bupranolol; Corticosterone; Desipramine; Ferrets; In Vitro Techniques; Ketamine; Myocardial Contraction; Papillary Muscles; Phentolamine; Reserpine; Stimulation, Chemical | 1991 |
Regulation of alpha and beta components of noradrenergic cyclic AMP response in cortical slices.
Topics: Adrenalectomy; Animals; Brain; Catecholamines; Cerebral Cortex; Corticosterone; Cosyntropin; Cyclic AMP; Desipramine; Hypophysectomy; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1987 |
Facilitatory presynaptic angiotensin receptors on the sympathetic nerves of the human saphenous vein and pulmonary artery. Potential involvement in beta-adrenoceptor-mediated facilitation of noradrenaline release.
Topics: Adrenergic Fibers; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin III; Cocaine; Corticosterone; Desipramine; Electric Stimulation; Female; Humans; Male; Norepinephrine; Pulmonary Artery; Receptors, Adrenergic, beta; Receptors, Angiotensin; Saphenous Vein; Saralasin | 1988 |
Chronic administration of tricyclic antidepressants suppresses hypothalamo-pituitary-adrenocortical activity in male rats.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Corticosterone; Desipramine; Dexamethasone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Imipramine; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains | 1988 |
On the opioid receptor subtype inhibiting the evoked release of 3H-noradrenaline from guinea-pig atria in vitro.
Topics: Animals; Atropine; Benzomorphans; Binding, Competitive; Corticosterone; Cyclazocine; Desipramine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Heart Atria; In Vitro Techniques; Morphine; Myocardium; Naloxone; Norepinephrine; Peptide Fragments; Phentolamine; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1986 |
Mechanisms of extraneuronal serotonin uptake in the rat aorta.
Topics: Animals; Aorta; Cocaine; Cold Temperature; Corticosterone; Desipramine; Hydroxydopamines; Imipramine; Kinetics; Male; Neurons; Norepinephrine; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Influence of serotonin on the immune response.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Antibody Formation; Corticosterone; Desipramine; Erythrocytes; Fenclonine; Hemolytic Plaque Technique; Immunoglobulin G; Immunoglobulin M; Mice; Mice, Inbred CBA; Serotonin | 1985 |
Effects of antidepressants on entrainment of circadian rhythms.
Topics: Animals; Body Temperature; Circadian Rhythm; Clomipramine; Corticosterone; Desipramine; Male; Melatonin; Rats; Rats, Inbred Strains | 1988 |
Stress and the hormonal regulation of the immune response in mice.
Topics: Acceleration; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Anesthesia; Animals; Antibody Formation; Antibody-Producing Cells; B-Lymphocytes; Cells, Cultured; Chromium Radioisotopes; Corticosterone; Crowding; Desipramine; Diazepam; Ethyl Ethers; Growth Hormone; Hemolytic Plaque Technique; Hypophysectomy; Immunosuppression Therapy; Macrophages; Mice; Pituitary Gland; Stress, Physiological; T-Lymphocytes | 1974 |
Brain amine changes in stressed and normal rats pretreated with various drugs.
Topics: Animals; Brain Chemistry; Corticosterone; Desipramine; Drug Antagonism; Male; Mesencephalon; Norepinephrine; Pargyline; Probenecid; Rats; Serotonin; Stress, Physiological; Telencephalon; Tyrosine | 1969 |
The effects of subchronic antidepressant drug treatment on the secretion of adenohypophyseal hormones and of corticosterone in the male rat.
Topics: Animals; Antidepressive Agents; Brompheniramine; Corticosterone; Desipramine; Male; Norepinephrine; Pituitary Hormones, Anterior; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission; Time Factors; Zimeldine | 1982 |
The effect of acute and chronic administration of desmethylimipramine on responses to stress in rats.
Topics: Acute Disease; Animals; Anorexia; Chronic Disease; Corticosterone; Depression; Desipramine; Electroshock; Feeding and Eating Disorders; Humans; Male; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological | 1984 |
A study on the effects of chlorpromazine and desipramine on rat adrenal steroidogenesis and cholesterol esterase activity.
Topics: Adrenal Glands; Animals; Carboxylic Ester Hydrolases; Chlorpromazine; Corticosterone; Desipramine; Male; Rats; Rats, Inbred Strains; Sterol Esterase | 1983 |
Prenatal stress prevents the desensitization of the corticosterone response to TFMPP by desmethylimipramine, but not by phenelzine, in adult male offspring.
Topics: Adaptation, Physiological; Animals; Antidepressive Agents; Corticosterone; Desipramine; Female; Male; Phenelzine; Piperazines; Pregnancy; Prolactin; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists; Stress, Physiological | 1995 |
Increased 5-HT2 receptor-mediated behavior 11 days after shock in learned helplessness rats.
Topics: Animals; Behavior, Animal; Corticosterone; Desipramine; Electroshock; Helplessness, Learned; Male; Rats; Rats, Wistar; Receptors, Serotonin; Time Factors | 1995 |
[Differences in the effects of glucocorticoids on beta-adrenergic receptor density in lung and cerebral cortex].
Topics: Animals; Cerebral Cortex; Corticosterone; Desipramine; Dihydroalprenolol; Lung; Male; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Tritium | 1995 |
Characterization of the effect of cocaine on catecholamine uptake by pregnant myometrium.
Topics: Analysis of Variance; Cocaine; Corticosterone; Desipramine; Ethylmaleimide; Female; Humans; In Vitro Techniques; Myometrium; Neurons; Norepinephrine; Pregnancy; Time Factors | 1995 |
Uptake of 3H-catecholamines by rat liver cells occurs mainly through a system which is distinct from uptake1 or uptake2.
Topics: Animals; Bilirubin; Catecholamines; Corticosterone; Desipramine; In Vitro Techniques; Liver; Male; Potassium; Probenecid; Quinolinium Compounds; Rats; Rats, Wistar; Sodium | 1994 |
pKI values of prazosin and idazoxan for receptors stimulated by neuronally released transmitter in the epididymal portion of rat isolated vas deferens.
Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Corticosterone; Desipramine; Dioxanes; Epididymis; Idazoxan; In Vitro Techniques; Male; Mathematics; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vas Deferens | 1994 |
Metabolism of [3H]-noradrenaline in human dental pulp in vitro.
Topics: Animals; Corticosterone; Dental Pulp; Desipramine; Humans; Norepinephrine; Rabbits; Receptors, Presynaptic | 1994 |
Effect of some neonatal treatments on the hypothalamic-pituitary-adrenocortical function.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Arousal; Cerebral Cortex; Clomipramine; Corticosterone; Desipramine; Dexamethasone; Emotions; Female; Hippocampus; Hypothalamo-Hypophyseal System; Male; Maternal Deprivation; Pituitary-Adrenal System; Rats; Restraint, Physical; Serotonin; Stress, Psychological | 1993 |
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Effect of dopexamine hydrochloride on sympathetic neuroeffector transmission in rabbit isolated pulmonary artery.
Topics: Animals; Catecholamines; Cocaine; Corticosterone; Desipramine; Dopamine; Dopamine Agonists; In Vitro Techniques; Pulmonary Artery; Rabbits; Vasoconstriction | 1996 |
The role of cerebral noradrenergic systems in the Fos response to interleukin-1.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Brain Chemistry; Cerebral Cortex; Corticosterone; Desipramine; Immunohistochemistry; Injections, Intraperitoneal; Injections, Intraventricular; Interleukin-1; Male; Mice; Mice, Inbred Strains; Neurons; Norepinephrine; Oxidopamine; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos | 1996 |
Chronic treatment with desipramine: effect on endocrine and behavioral responses induced by inescapable stress.
Topics: Animals; Behavior, Animal; Corticosterone; Desipramine; Disease Models, Animal; Escape Reaction; Male; Rats; Rats, Wistar; Stress, Physiological; Time Factors | 1997 |
Catecholamine uptake and metabolism in the liver.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Corticosterone; Desipramine; Epinephrine; In Vitro Techniques; Liver; Norepinephrine; Rats | 1998 |
Forced swim test-induced endocrine and immune changes in the rat: effect of subacute desipramine treatment.
Topics: Adrenal Glands; Animals; Antidepressive Agents, Tricyclic; Ascorbic Acid; Corticosterone; Depression; Desipramine; Disease Models, Animal; Drug Evaluation, Preclinical; Endocrine System; Immune System; Leukocytes; Male; Organ Size; Rats; Rats, Sprague-Dawley; Swimming | 1998 |
The effect of chronic administration of antidepressants on the circadian pattern of corticosterone in the rat.
Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clomipramine; Corticosterone; Desipramine; Hypothalamo-Hypophyseal System; Imipramine; Male; Phenelzine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley | 1998 |
Modulation by presynaptic beta-adrenoceptors of noradrenaline release from sympathetic nerves in human dental pulp.
Topics: Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Albuterol; Anti-Inflammatory Agents; Corticosterone; Dental Pulp; Desipramine; Electric Stimulation; Ethanolamines; Female; Humans; Isoproterenol; Male; Norepinephrine; Propranolol; Radiopharmaceuticals; Receptors, Adrenergic, beta; Receptors, Presynaptic; Sympathetic Nervous System; Sympatholytics; Sympathomimetics; Tritium; Yohimbine | 1998 |
Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship.
Topics: Adrenergic Uptake Inhibitors; Arachidonic Acids; Atrial Function; Corticosterone; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Electrophysiology; Endocannabinoids; Excitatory Amino Acid Agonists; Female; Guanidine; Humans; Imidazoles; Imidazoline Receptors; Ligands; Male; Norepinephrine; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Receptors, Presynaptic; Sympathetic Nervous System; Sympathomimetics | 1999 |
Electrochemical and electrophysiological characterization of neurotransmitter release from sympathetic nerves supplying rat mesenteric arteries.
Topics: Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Cadmium; Corticosterone; Desipramine; Electric Conductivity; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Female; Idazoxan; In Vitro Techniques; Kinetics; Membrane Potentials; Mesenteric Arteries; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Tetrodotoxin | 1999 |
Olfactory bulbectomy provokes a suppression of interleukin-1beta and tumour necrosis factor-alpha production in response to an in vivo challenge with lipopolysaccharide: effect of chronic desipramine treatment.
Topics: Adrenal Cortex; Animals; Antidepressive Agents, Tricyclic; Ascorbic Acid; Behavior, Animal; Corticosterone; Depression; Desipramine; Disease Models, Animal; Hypothalamo-Hypophyseal System; Interleukin-1; Lipopolysaccharides; Male; Neuroimmunomodulation; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2000 |
Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test.
Topics: Amygdala; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Biogenic Amines; Brain Chemistry; Cerebral Cortex; Corticosterone; Cyclohexanols; Depressive Disorder; Desipramine; Hormones; Hypothalamo-Hypophyseal System; Male; Motor Activity; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Swimming; Venlafaxine Hydrochloride | 2000 |
Differential regulation of neuropeptide Y mRNA expression in the arcuate nucleus and locus coeruleus by stress and antidepressants.
Topics: Adrenalectomy; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arcuate Nucleus of Hypothalamus; Corticosterone; Desipramine; Gene Expression Regulation; In Situ Hybridization; Insulin; Locus Coeruleus; Male; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Stress, Physiological | 2000 |
Prejunctional muscarinic receptor modulation of noradrenaline release from sympathetic neurones in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Carbachol; Cocaine; Corticosterone; Desipramine; Drug Interactions; Electric Stimulation; Female; In Vitro Techniques; Male; Neurons; Norepinephrine; Rabbits; Receptors, Muscarinic; Receptors, Presynaptic; Sympathetic Nervous System | 2000 |
Desipramine antagonized corticosterone-induced apoptosis in cultured PC12 cells.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Apoptosis; Corticosterone; Desipramine; DNA Fragmentation; Electrophoresis, Agar Gel; PC12 Cells; Rats | 2002 |
cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Crosses, Genetic; Cyclic AMP Response Element-Binding Protein; Desipramine; Endocrine System; Exercise Test; Fluoxetine; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Motor Activity; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Transcription, Genetic; Up-Regulation | 2002 |
Sympathetic nervous system plays a major role in acute cold/restraint stress inhibition of host resistance to Listeria monocytogenes.
Topics: Acute Disease; Animals; Cold Temperature; Corticosterone; Desipramine; Enzyme Inhibitors; Immunity, Innate; Listeriosis; Male; Metyrapone; Mice; Mice, Inbred BALB C; Neuroimmunomodulation; Oxidopamine; Restraint, Physical; Stress, Physiological; Sympathectomy, Chemical; Sympathetic Nervous System; Sympatholytics | 2002 |
Inhibition of the oligosaccharides extracted from Morinda officinalis, a Chinese traditional herbal medicine, on the corticosterone induced apoptosis in PC12 cells.
Topics: Animals; Antidepressive Agents; Cell Count; Corticosterone; Desipramine; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Antagonism; Drugs, Chinese Herbal; Flow Cytometry; Morinda; Oligosaccharides; PC12 Cells; Rats | 2003 |
1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3.
Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents; Biological Transport; Cell Survival; Cells, Cultured; Cerebellum; Corticosterone; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Female; Male; Neurons; Neuroprotective Agents; Organic Cation Transport Proteins; Piperazines; Quinolines; Rats; RNA, Messenger; Rotenone; Temperature | 2003 |
Cytoprotective effect is one of common action pathways for antidepressants.
Topics: Animals; Anticonvulsants; Calcium; Cell Survival; Corticosterone; Desipramine; Fluoxetine; Moclobemide; Nerve Growth Factor; Neuroprotective Agents; PC12 Cells; Rats; RNA, Messenger | 2003 |
Total sleep deprivation decreases immobility in the forced-swim test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Desipramine; Disease Models, Animal; Electroencephalography; Electromyography; Immobilization; Motor Activity; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sleep Deprivation; Sleep Stages; Swimming; Time Factors; Wakefulness | 2004 |
Inducible cAMP early repressor regulates corticosterone suppression after tricyclic antidepressant treatment.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Cyclic AMP Response Element Modulator; Desipramine; DNA-Binding Proteins; Gene Expression; Hypothalamo-Hypophyseal System; Mice; Mice, Knockout; Mice, Mutant Strains; Neurons; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological | 2004 |
The cytoprotective effect of inulin-type hexasaccharide extracted from Morinda officinalis on PC12 cells against the lesion induced by corticosterone.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Calcium; Cell Survival; Corticosterone; Cytoprotection; Desipramine; DNA Primers; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fluorometry; Fura-2; Gene Expression Regulation; Morinda; Nerve Growth Factor; Neuroprotective Agents; Oligosaccharides; PC12 Cells; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Antidepressant action of agomelatine (S 20098) in a transgenic mouse model.
Topics: Acetamides; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Desipramine; Disease Models, Animal; In Situ Hybridization; Male; Maze Learning; Melatonin; Mice; Mice, Transgenic; Receptors, Glucocorticoid; Swimming; Telemetry; Time Factors | 2005 |
Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: differential regulation of specific exons by antidepressants and corticosterone.
Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Desipramine; Drug Implants; Exons; Fluoxetine; Gene Expression; Male; Phenelzine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 2006 |
Hippocampal cell proliferation regulation by repeated stress and antidepressants.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Proliferation; Corticosterone; Desipramine; Electroshock; Fluoxetine; Helplessness, Learned; Hippocampus; Immunohistochemistry; Male; Neurons; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2006 |
The comparison of immobility time in experimental rat swimming models.
Topics: Animals; Blood Glucose; Corticosterone; Desipramine; Diazepam; Glycogen; Immobilization; Liver; Male; Models, Biological; Rats; Rats, Wistar; Stress, Psychological; Swimming; Time Factors | 2006 |
The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Corticosterone; Desipramine; Hippocampus; In Situ Hybridization; Male; Mice; Mice, Knockout; Receptors, Glucocorticoid; RNA, Messenger; Up-Regulation | 2007 |
Increased water temperature renders single-housed C57BL/6J mice susceptible to antidepressant treatment in the forced swim test.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Corticosterone; Data Interpretation, Statistical; Depression; Desipramine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Motor Activity; Social Isolation; Species Specificity; Swimming; Temperature | 2008 |
Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice.
Topics: Adaptation, Psychological; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Desipramine; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction; Statistics, Nonparametric; Stress, Psychological; Swimming; Time Factors | 2008 |
An anti-immobility effect of exogenous corticosterone in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Immobility Response, Tonic; Male; Mice; Proto-Oncogene Proteins c-fos; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Swimming | 2008 |
The role of the arginine vasopressin Avp1b receptor in the acute neuroendocrine action of antidepressants.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arginine Vasopressin; Corticosterone; Corticotropin-Releasing Hormone; Desipramine; Female; Fluoxetine; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Knockout; Oxytocin; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Receptors, Vasopressin; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Sex Factors | 2008 |
Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain Chemistry; Corticosterone; Depressive Disorder; Desipramine; Exploratory Behavior; Fluoxetine; Genes, fos; Image Processing, Computer-Assisted; In Situ Hybridization; Individuality; Male; Motor Activity; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming | 2008 |
Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex.
Topics: Animals; Antidepressive Agents, Tricyclic; Apoptosis; Caspase 3; Cerebral Cortex; Chronic Disease; Corticosterone; Desipramine; Disease Models, Animal; Male; Neurons; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2008 |
Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Biomarkers, Pharmacological; Corticosterone; Depression; Desipramine; Disease Models, Animal; Escape Reaction; Helplessness, Learned; Hippocampus; Male; Motor Cortex; Rats; Rats, Sprague-Dawley; Stress, Physiological; Synapses | 2009 |
Uptake of mIBG and catecholamines in noradrenaline- and organic cation transporter-expressing cells: potential use of corticosterone for a preferred uptake in neuroblastoma- and pheochromocytoma cells.
Topics: 3-Iodobenzylguanidine; Animals; Biological Transport; Catecholamines; Cell Line, Tumor; Corticosterone; Desipramine; Dopamine; Gene Expression Regulation, Neoplastic; Humans; Ion Pumps; Neuroblastoma; Norepinephrine Plasma Membrane Transport Proteins; Organic Cation Transport Proteins; Pheochromocytoma | 2009 |
Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in a rat model of Parkinson's disease.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Cell Count; Corpus Striatum; Corticosterone; Cytokines; Desipramine; Disease Models, Animal; Dopamine; Flow Cytometry; Immunohistochemistry; Leukocytes; Lipopolysaccharides; Male; Oxidopamine; Parkinson Disease; Prolactin; Rats; Rats, Inbred F344; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2009 |
Nerve growth factor (NGF) has novel antidepressant-like properties in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain; Corticosterone; Desipramine; Disease Models, Animal; Drug Interactions; Fluoxetine; Hypothermia; Motor Activity; Nerve Growth Factor; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serotonin Agents; Social Behavior; Swimming | 2010 |
Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs.
Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Aldehyde-Lyases; Animals; Astrocytes; Benserazide; Brain; Chemokine CCL2; Corticosterone; Desipramine; Drug Administration Routes; Enzyme Inhibitors; Female; Gene Expression Regulation; Male; Metyrapone; Mice; Mice, Inbred C57BL; Norepinephrine; Propranolol; Rats; Rats, Wistar; Restraint, Physical; RNA, Messenger; Stress, Physiological | 2010 |
gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depressive Disorder; Desipramine; Disease Models, Animal; Female; Fluoxetine; Hypothalamo-Hypophyseal System; Mice; Mice, Knockout; Pituitary-Adrenal System; Receptors, GABA-A; Selective Serotonin Reuptake Inhibitors | 2010 |
Desipramine treatment has minimal effects on the brain accumulation of glucocorticoids in P-gp-deficient and wild-type mice.
Topics: Animals; Antidepressive Agents, Tricyclic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Choroid Plexus; Corticosterone; Desipramine; Dexamethasone; Glucocorticoids; Male; Mice; Mice, Knockout; Pituitary Gland | 2011 |
Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Dark Adaptation; Desipramine; Disease Models, Animal; Exploratory Behavior; Fever; Food Deprivation; Hypothalamo-Hypophyseal System; Magnesium; Magnesium Deficiency; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Paroxetine; Pituitary-Adrenal System; Protein Precursors; Proto-Oncogene Proteins c-fos; Radioimmunoassay; Reaction Time; RNA, Messenger; Stress, Psychological | 2012 |
Aberrant light directly impairs mood and learning through melanopsin-expressing neurons.
Topics: Affect; Animals; Antidepressive Agents; Body Temperature Regulation; Circadian Rhythm; Cognition; Corticosterone; Depression; Desipramine; Fluoxetine; Learning; Light; Long-Term Potentiation; Male; Memory; Mice; Photoperiod; Retinal Ganglion Cells; Rod Opsins; Sleep; Wakefulness | 2012 |
Chronic antidepressant desipramine treatment increases open field-induced brain expression and spleen production of interleukin 10 in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Corticosterone; Desipramine; Exploratory Behavior; Interferon-gamma; Interleukin-10; Interpersonal Relations; Killer Cells, Natural; Leukocytes, Mononuclear; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spleen; Statistics, Nonparametric; Time Factors | 2013 |
Chronic desipramine prevents acute stress-induced reorganization of medial prefrontal cortex architecture by blocking glutamate vesicle accumulation and excitatory synapse increase.
Topics: Animals; Antidepressive Agents, Tricyclic; Corticosterone; Desipramine; Disease Models, Animal; Electroshock; Glutamic Acid; Male; Microscopy, Electron, Transmission; Models, Neurological; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Psychological; Synapses; Synaptic Vesicles; Time Factors; Vesicular Glutamate Transport Protein 1 | 2014 |
Melancholic-Like behaviors and circadian neurobiological abnormalities in melatonin MT1 receptor knockout mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Chronobiology Disorders; Circadian Rhythm; Corticosterone; Depressive Disorder; Desipramine; Disease Models, Animal; Exploratory Behavior; Feeding Behavior; Food Preferences; Hindlimb Suspension; Male; Maze Learning; Mice; Mice, Knockout; Receptor, Melatonin, MT1; Swimming | 2015 |
Changes in blood CD4+T and CD8+T lymphocytes in stressed rats pretreated chronically with desipramine are more pronounced after chronic open field stress challenge.
Topics: Animals; Antidepressive Agents, Tricyclic; Apoptosis; Body Weight; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chronic Disease; Corticosterone; Desipramine; Disease Models, Animal; Drug Administration Schedule; Exploratory Behavior; Flow Cytometry; Interferon-gamma; Interleukin-10; Leukocytes; Male; Rats; Rats, Wistar; Stress, Psychological | 2015 |
Temporal Dynamics of Acute Stress-Induced Dendritic Remodeling in Medial Prefrontal Cortex and the Protective Effect of Desipramine.
Topics: Actin Depolymerizing Factors; Animals; Antidepressive Agents, Tricyclic; Atrophy; Body Weight; Corticosterone; Dendrites; Desipramine; Electroshock; Foot; Male; Neuronal Plasticity; Prefrontal Cortex; Pyramidal Cells; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Time Factors | 2017 |
The expression of plasticity-related genes in an acute model of stress is modulated by chronic desipramine in a time-dependent manner within medial prefrontal cortex.
Topics: Actin Depolymerizing Factors; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Desipramine; Disease Models, Animal; Electroshock; Gene Expression Regulation; Male; Microfilament Proteins; Nerve Tissue Proteins; Neuronal Plasticity; Prefrontal Cortex; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Stress, Psychological; Time Factors | 2017 |
Macathiohydantoin
Topics: Animals; Cell Survival; Corticosterone; Desipramine; Humans; Lepidium; Neuroprotective Agents; PC12 Cells; Plant Extracts; Pyridines; Rats; Thiohydantoins | 2021 |