desipramine has been researched along with clonidine in 231 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 119 (51.52) | 18.7374 |
| 1990's | 41 (17.75) | 18.2507 |
| 2000's | 35 (15.15) | 29.6817 |
| 2010's | 33 (14.29) | 24.3611 |
| 2020's | 3 (1.30) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Giacomini, KM; Schaner, ME; Zhang, L | 1 |
| Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Conway, SJ; Ganapathy, ME; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wang, H; Wu, X | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Akamatsu, M | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, ZF; Huang, SL; Huang, ZS; Liang, H; Qin, JK; Tang, H; Zhao, HT; Zhao, LZ; Zhong, SM | 1 |
| Chen, ZF; Liang, H; Tang, H; Wang, ZY; Zhao, HT; Zhong, SM | 1 |
| Chen, J; Chen, X; Huang, L; Li, X; Sun, Y | 1 |
| Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E | 1 |
| Huang, L; Li, X; Meng, F; Miao, H; Sun, Y | 1 |
| Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW | 1 |
| Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW | 1 |
| Chen, W; Huangli, Y; Qin, J; Shen, Y; Tang, H; Wang, L; Wei, S | 1 |
| Chen, EC; Chien, HC; Giacomini, KM; Huang, Y; Khuri, N; Liang, X; Sali, A; Stecula, A; Yee, SW | 1 |
| Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| An, B; Hu, J; Huang, L; Li, X; Li, Z; Pan, T | 1 |
| Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Chen, L; Chen, Y; Duan, Y; Feng, F; Huang, J; Jiang, X; Liu, C; Liu, W; Qu, W; Sun, H; Wang, Y; Zhou, J | 1 |
| Chen, T; Chen, Y; Feng, F; Jiang, X; Li, Q; Liu, C; Liu, W; Lyu, W; Sun, H; Wang, S; Wang, Y; Xing, C | 1 |
| Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Clineschmidt, BV; Scriabine, A; Sweet, CS | 1 |
| Draper, AJ; Grimes, D; Redfern, PH | 1 |
| Doxey, JC | 1 |
| Bohidar, NR; Ludden, CT; Scriabine, A; Stavorski, JM; Sweet, CS; Wenger, HC | 1 |
| Endoh, M; Shimizu, T; Yanagisawa, T | 1 |
| Doxey, JC; Everitt, J; Metcalf, G | 1 |
| de Champlain, J; Nadeau, RA; Yamaguchi, N | 1 |
| Dubocovich, ML; Langer, SZ; Pelayo, F | 2 |
| Helmeste, DM; Stancer, HC; Tang, SW | 1 |
| Scriabine, A; Stavorski, JM | 1 |
| Chen, CS; Ozawa, H; Uematsu, T; Watanabe, H | 1 |
| Zwieten, PA | 1 |
| Ozawa, H; Uematsu, T | 1 |
| van Zwieten, PA | 1 |
| Monti, JM; Ruiz, M | 1 |
| Grewal, RS; Kaul, CL | 1 |
| Cancela, LM; Molina, VA; Volosin, M | 1 |
| Charles, G; Machowski, R; Nefve, C; Schittecatte, M; Valentin, JG; Wilmotte, J | 1 |
| Coupland, N; Glue, P | 1 |
| Greenhill, LL | 1 |
| Barturen, F; Garcia-Sevilla, JA | 1 |
| Andrioli, GC; Bonanno, G; Maura, G; Pende, M; Raiteri, M; Ruelle, A | 1 |
| Grealy, M; O'Donnell, JM | 2 |
| Blier, P; Curet, O; de Montigny, C; Lacroix, D | 1 |
| Buckett, WR; Heal, DJ; Prow, MR | 1 |
| Kunimi, Y; Naitoh, H; Nomura, S; Sekiya, Y; Sugita, R | 1 |
| Cervo, L; Samanin, R | 1 |
| Halaris, A; Marler, MR; Piletz, JE; Saran, A | 1 |
| Chotani, M; Halaris, A; Piletz, JE; Saran, A; Sarasua, M | 1 |
| Marshall, IG; Prior, C; Wannan, G | 1 |
| Cai, B; Matsumoto, K; Ohta, H; Satoh, T; Watanabe, H | 1 |
| Keller, EA; Molina, VA; Orsingher, OA | 1 |
| Ferraino, R; Fritz, PM; Hamel, LT; Haubrich, DR; Luttinger, D; Perrone, MH | 1 |
| Cox, HS; Eisenhofer, G; Esler, MD | 1 |
| Gerlich, M; Graefe, KH; Halbrügge, T; Ludwig, J | 1 |
| Becker, CA; Commissaris, RL; Ellis, DM; Fontana, DJ; Hill, TJ; Schefke, DM | 1 |
| Buckett, WR; Heal, DJ; Hurst, EM; Prow, MR | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Campbell, IC; Ellison, DW | 1 |
| Luscombe, DK; Mustafa, MR; Stolz, JF | 1 |
| Brunello, N; Galimberti, R; Racagni, G; Riva, M; Rovescalli, AC | 1 |
| Bristow, LM; Buckett, WR; Elliott, JM; Heal, DJ; Hurst, EM | 1 |
| Davis, JM; Janicak, PG; Javaid, JI; Pandey, GN | 1 |
| Balfagón, G; Marín, J | 1 |
| Angus, JA; Dyke, AC; Korner, PI | 1 |
| Limberger, N; Mayer, A; Singer, EA; Starke, K; Valenta, B; Zier, G | 1 |
| Bill, DJ; Hughes, IE; Stephens, RJ | 1 |
| de Jong, W; van den Buuse, M | 1 |
| Carvalho, F; Gonçalves, J; Guimarães, S | 1 |
| Archer, T; Danysz, W; Jonsson, G; Minor, BG; Mohammed, AK; Post, C | 1 |
| Atterwill, CK; Bloomfield, JG; Bristow, LJ; Catto, LC; Elliott, JM; Heal, DJ | 1 |
| Drobny, H; Singer, EA; Valenta, B | 1 |
| Bloomfield, JG; Bristow, LJ; De Souza, RJ; Elliott, JM; Heal, DJ; Hurst, EM | 1 |
| Arbilla, S; Benkirane, S; Langer, SZ | 1 |
| Asakura, M; Tsukamoto, T | 1 |
| Curet, O; Dennis, T; L'Heureux, R; Scatton, B | 1 |
| Hedler, L; Starke, K; Szabo, B | 1 |
| Green, AR | 1 |
| Halaris, A; Piletz, JE | 1 |
| Cichini, G; Lassmann, H; Placheta, P; Singer, EA | 1 |
| Brambilla, F; Candolfi, C; Cavagnini, F; Invitti, C; Lampertico, M; Maggioni, M; Müller, EE; Panerai, AE; Sali, L | 1 |
| Ensinger, H; Hedler, L; Majewski, H; Starke, K | 1 |
| Swann, AC | 1 |
| Campbell, IC; McKernan, RM | 1 |
| Convery, ME; Domino, EF; Selden, EM; Stites, MM | 1 |
| Arendt, J; Checkley, SA; Corn, TH; Franey, C; Glass, IB; Thompson, C | 1 |
| Campbell, IC; McWilliam, JR | 2 |
| Brambilla, F; Cavagnini, F; Ferrari, E; Massironi, R; Müller, EE; Panerai, AE | 1 |
| Jaffer, A; Russell, VA; Taljaard, JJ | 1 |
| Marwah, J; Pitts, DK | 1 |
| Abercrombie, ED; Keller, RW; Zigmond, MJ | 1 |
| Abrahamsson, T; Carlsson, L | 1 |
| Eisenhofer, G; Folio, CJ; Goldstein, DS; Keiser, HR; Kopin, IJ; Stull, R | 1 |
| Leonard, BE; O'Connor, WT | 1 |
| Ferron, A; Lacroix, D | 1 |
| Cohen, BS; Dillon, D; Fyer, AJ; Gorman, JM; Klein, DF; Liebowitz, MR | 1 |
| Insel, TR; Lane, EA; Linnoila, M; Sheinin, M | 1 |
| Baiguerra, G; Kostowski, W; Valzelli, L | 1 |
| Hoffman, LJ; Weiss, JM | 1 |
| Duman, R; Hewitt, L; Swann, AC | 1 |
| Blask, DE; Stockmeier, CA | 1 |
| Abrahamsen, J; Nedergaard, OA | 1 |
| Aulakh, CS; Cohen, RM; Murphy, DL; Pradhan, SN | 1 |
| Nurse, B; Russell, VA; Taljaard, JJ | 1 |
| Farnebo, LO; Hamberger, B | 3 |
| Finch, L | 1 |
| Briant, RH; Dollery, CT; Reid, JL | 2 |
| Briant, RH; Reid, JL | 1 |
| van Spanning, HW; van Zwieten, PA | 1 |
| Matussek, N | 2 |
| Checkley, SA; Corn, TH; Thompson, C | 1 |
| Danysz, W; Kostowski, W; Płaznik, A | 1 |
| Garver, DL; Greenblum, DN; Kanter, DR; Mavroidis, ML | 1 |
| German, DC; McMillen, BA; Shore, PA; Warnack, W | 1 |
| Bergstrom, DA; Walters, JR | 1 |
| Liebowitz, MR | 1 |
| Hedler, L; Majewski, H; Starke, K | 1 |
| Borsini, F; Nowakowska, E; Samanin, R | 1 |
| Collett, AR; Story, DF | 1 |
| Bonanno, G; Marchi, M; Maura, G; Raiteri, M | 1 |
| Lane, EA; Potter, WZ; Rudorfer, MV | 1 |
| Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG | 1 |
| Baumann, PA; Koella, WP | 1 |
| Johnson, RW; Reisine, T; Spotnitz, S; Ursillo, R; Wiech, N; Yamamura, HI | 1 |
| Robie, NW | 1 |
| Fibiger, HC; Spyraki, C | 1 |
| Checkley, SA; Dawling, S; Shur, E; Slade, AP | 1 |
| García-Sevilla, JA; Hollingsworth, PJ; Smnith, CB | 1 |
| Charney, DS; Heninger, GR; Leckman, JF; Maas, JW; Redmond, DE; Roth, RH; Sternberg, DE | 1 |
| Andréjak, M; Dabiré, H; Lucet, B; Mouillé, P; Pommier, Y; Schmitt, H | 1 |
| Sugrue, MF | 3 |
| Scuvée-Moreau, JJ; Svensson, TH | 1 |
| Davis, M; Menkes, DB | 1 |
| Checkley, SA; Dawling, S; Glass, IB; Shur, E | 1 |
| Kalkman, HO; Timmermans, PB; van Gelderen, EM; van Zwieten, PA | 1 |
| Checkley, SA; McWilliam, JR; Meldrum, BS | 1 |
| Gaillard, JM; Justafre, JC; Kafi, S | 1 |
| Davies, CL; Green, AR; Heal, DJ; Lister, S; Molyneux, SG; Smith, SL | 1 |
| Cloutier, G; Cubeddu, LX; Grippo, R; Gross, K; Harden, TK; Knowlton, G; Lerea, L; Shakarjian, M; Stat, M; Tanner, L | 1 |
| Dyr, W; Kostowski, W; Zacharski, B | 1 |
| Maura, G; Pittaluga, A; Raiteri, M; Ricchetti, A | 1 |
| Buda, M; De Simoni, G; Gonon, F; Pujol, JF | 1 |
| Kitada, Y; Kosasa, T; Miyauchi, T; Satoh, S | 1 |
| Anderson, S; Appleby, IL; Davies, SO; Dillon, D; Fyer, AJ; Gorman, JM; Levitt, M; Levy, G; Liebowitz, MR; Palij, M | 1 |
| Kwan, S; Seeman, P; Tang, SW | 1 |
| Charney, DS; Heninger, GR; Sternberg, DE | 1 |
| Mogilnicka, E | 1 |
| Oguma, M; Ohkubo, K; Otorii, T; Suzuki, K | 1 |
| Cheal, M | 1 |
| Bobik, A; Jackman, G; Skews, H; Snell, J | 1 |
| Aghajanian, GK | 1 |
| Strömbom, U; Svensson, TH | 1 |
| Brown, J; Denckla, MB; Mellits, ED; Quaskey, S; Rosenberg, LA; Singer, HS | 1 |
| Finlay, JM; Gresch, PJ; Sved, AF; Zigmond, MJ | 1 |
| Klemfuss, H; Kripke, DF | 1 |
| Cosentino, M; De Ponti, F; Frigo, GM; Lecchini, S; Marcoli, M; Marino, F | 1 |
| Shores, MM; Szot, P; Veith, RC | 1 |
| Brun, P; Buda, M; Gonon, F; Suaud-Chagny, MF | 1 |
| Blier, P; de Montigny, C; Mongeau, R | 1 |
| Fujita, K; Iijima, N; Nakazawa, K; Suzuki, S | 1 |
| Biederman, J; Spencer, T; Steingard, R; Wilens, T | 1 |
| Nomura, S; Sawa, Y; Sekiya, Y; Sugita, R; Terada, K | 1 |
| Artigas, F; Bel, N | 1 |
| Badia, A; Giraldo, J; Sallés, J; Vila, E | 1 |
| Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL | 1 |
| Baranyi, M; Bencsics, A; Hashim, A; Lajtha, A; Sershen, H; Vizi, ES | 1 |
| Coote, M; Steiner, M; Werstiuk, ES; Wilkins, A | 1 |
| Blier, P; de Montigny, C; Mongeau, R; Weiss, M | 1 |
| Shannon, HE; Womer, DE | 1 |
| Nath, C; Srivastava, SK | 1 |
| Bernini, M; Gobbi, M; Mennini, T; Parini, S; Pirona, L; Sacchetti, G; Samanin, R | 1 |
| Harkin, A; Kelly, JP; Leonard, BE; Morris, K; O'Donnell, JM | 1 |
| Fernández-Pastor, B; Mateo, Y; Meana, JJ | 1 |
| Cuadra, GR; Nasif, FJ; Orsingher, OA; Ramírez, OA | 1 |
| Nott, MW; Rand, MJ; Thaina, P | 1 |
| Carrey, NJ; Clements, R; Dursun, S; MacMaster, FP; Renton, K; Waschbusch, D | 1 |
| Bouvard, M; Rénéric, JP; Stinus, L | 1 |
| Eckhardt, K; Feuerstein, TJ; Günter, T; Roth, P; Schmidt, S | 1 |
| Devoto, P; Flore, G; Gessa, GL; Longu, G; Pira, L | 1 |
| Barrera, G; Burke, TF; Garcia, AS; Hensler, JG; Ma, S; Morilak, DA | 1 |
| Banaschewski, T; Heise, CA; Himpel, S; Rothenberger, A | 1 |
| Ignatowski, TA; Reynolds, JL; Spengler, RN; Sud, R | 1 |
| Schoffelmeer, AN; van Gaalen, MM; van Koten, R; Vanderschuren, LJ | 1 |
| Hamrin, V; Rains, A; Scahill, L | 1 |
| Inazu, M; Matsumiya, T; Tajima, H; Takeda, H; Uchida, Y; Yamada, T | 1 |
| Esler, MD; Lambert, G; Mitchell, DA; Raven, PB; Secher, NH; van Lieshout, J | 1 |
| Pattij, T; Schetters, D; Schoffelmeer, AN; van Gaalen, MM | 1 |
| García-Bueno, B; Hinojosa, AE; Leza, JC; Madrigal, JL | 1 |
| Alba-Delgado, C; Berrocoso, E; Borges, G; Horrillo, I; Meana, JJ; Mico, JA; Neto, F; Ortega, JE; Sánchez-Blázquez, P | 1 |
| Drugan, RC; Warner, TA | 1 |
| Brock, JA; McLachlan, EM; Tripovic, D | 1 |
| Castells, X; Ehimare, UP; Otasowie, J; Smith, CH | 1 |
| Angus, JA; Rajasekaran, P; Wright, CE | 1 |
| Osland, ST; Pringsheim, T; Steeves, TD | 1 |
10 review(s) available for desipramine and clonidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacologic treatment of attention deficit hyperactivity disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Preschool; Clonidine; Desipramine; Female; Humans; Male; Methylphenidate | 1992 |
[Antidepressant drugs and central monoaminergic receptors].
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Antipsychotic Agents; Binding Sites; Blood Platelets; Brain; Brain Chemistry; Cats; Clonidine; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Mianserin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Yohimbine | 1985 |
Evolving concepts on the interactions between antidepressant treatments and monoamine neurotransmitters.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Body Temperature Regulation; Brain Chemistry; Cerebral Cortex; Clonidine; Desipramine; Drug Interactions; Electroshock; Neurons; Neurotransmitter Agents; Receptors, Adrenergic, beta; Receptors, GABA-A; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Zimeldine | 1987 |
Drugs as tools for exploring neuroendocrine functions.
Topics: Alcoholism; Clonidine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Insulin; Male; Menopause; Menstruation; Pituitary Gland, Anterior; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1984 |
Newer uses for older psychotropic medications.
Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive Disorder; Desipramine; Humans; Imipramine; Lithium; Monoamine Oxidase Inhibitors; Personality Disorders; Phenelzine; Propranolol; Psychotropic Drugs; Schizophrenia | 1982 |
[Neurobiologic aspects of depression].
Topics: Amphetamine; Animals; Blood Platelets; Cholinergic Fibers; Clonidine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Hydrocortisone; Male; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Neurotransmitter | 1983 |
The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder.
Topics: Adrenergic alpha-Agonists; Adult; Antidepressive Agents, Tricyclic; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Guanfacine; Humans; Imipramine; Nortriptyline; Propylamines | 2005 |
Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Clonidine; Desipramine; Humans; Methylphenidate; Randomized Controlled Trials as Topic; Tic Disorders; Tourette Syndrome | 2014 |
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Preschool; Clonidine; Desipramine; Dextroamphetamine; Female; Guanfacine; Humans; Male; Methylphenidate; Randomized Controlled Trials as Topic; Selegiline; Tic Disorders | 2018 |
4 trial(s) available for desipramine and clonidine
| Article | Year |
|---|---|
Interaction between clonidine and desipramine in man.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Desipramine; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Posture | 1973 |
Bupropion does not antagonize cardiovascular actions of clonidine in normal subjects and spontaneously hypertensive rats.
Topics: Adult; Animals; Blood Platelets; Blood Pressure; Bupropion; Clonidine; Desipramine; Heart Rate; Humans; Imipramine; In Vitro Techniques; Male; Propiophenones; Rats; Rats, Inbred Strains; Tritium; Yohimbine | 1984 |
The treatment of attention-deficit hyperactivity disorder in Tourette's syndrome: a double-blind placebo-controlled study with clonidine and desipramine.
Topics: Adolescent; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Desipramine; Double-Blind Method; Female; Humans; Male; Tourette Syndrome; Treatment Outcome | 1995 |
Effects of electroconvulsive therapy and desipramine on neuroendocrine responses to the clonidine challenge test.
Topics: Adrenergic alpha-Agonists; Aged; Antidepressive Agents, Tricyclic; Clonidine; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales | 1998 |
217 other study(ies) available for desipramine and clonidine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection | 1998 |
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium | 1999 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Binding, Competitive; Carbon Radioisotopes; Cations; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Dopamine Agents; Exons; Gene Expression Regulation; HeLa Cells; Herbicides; Humans; In Situ Hybridization; Introns; Kidney; Mice; Niacinamide; Octamer Transcription Factor-3; Oocytes; Pigment Epithelium of Eye; RNA, Messenger; Tetraethylammonium; Transcription Factors; Tritium; Xenopus laevis | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Aporphines; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Horses; Humans; Models, Biological; Tacrine | 2011 |
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Membranes, Artificial; Models, Molecular; Molecular Structure; Permeability; Protein Binding | 2012 |
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electrophorus; Humans; Isoflavones; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Swine; Tacrine | 2013 |
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding | 2014 |
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies | 2014 |
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins | 2014 |
Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Indans; Inhibitory Concentration 50; Ligands; Peptide Fragments; Permeability; Protein Aggregates | 2014 |
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship | 2014 |
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi | 2015 |
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship | 2016 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2016 |
Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Autophagy; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Protein Aggregates; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).
Topics: Drug Discovery; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Organic Cation Transporter 1; Small Molecule Libraries | 2017 |
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species | 2017 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Drug Design; Humans; Ligands; Mice; Rats; Rolipram | 2019 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine | 2019 |
Rational design and biological evaluation of a new class of thiazolopyridyl tetrahydroacridines as cholinesterase and GSK-3 dual inhibitors for Alzheimer's disease.
Topics: Acetylcholinesterase; Acridines; Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Glycogen Synthase Kinase 3; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Morris Water Maze Test; Phosphorylation; Protein Conformation; tau Proteins; Thiazoles | 2020 |
Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Glycogen Synthase Kinase 3 beta; Humans; Molecular Structure; Neuroprotective Agents; Protein Kinase Inhibitors; Pyridines; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured | 2021 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
Central noradrenergic control of blood pressure.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dogs; Drug Interactions; Hemodynamics; Hypertension; Methyldopa; Neurons; Norepinephrine; Rabbits; Rats; Receptors, Drug | 1976 |
The interaction between clonidine and desmethylimipramine: effects on blood pressure and central catecholamine metabolism [proceedings].
Topics: Animals; Blood Pressure; Brain; Clonidine; Desipramine; Drug Interactions; Hypothalamus; Medulla Oblongata; Norepinephrine; Rats | 1976 |
Effect of clonidine on cardiac acceleration in pithed rats.
Topics: Adrenal Glands; Animals; Blood Pressure; Clonidine; Desipramine; Electric Stimulation; Heart; Heart Rate; Male; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1977 |
Some cardiovascular effects of ST-91 and clonidine.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Desipramine; Dogs; Electric Stimulation; Female; Heart Rate; Hemodynamics; Hypertension; Imidazoles; Injections, Intraventricular; Male; Phenoxybenzamine; Phentolamine; Rats; Time Factors; Vagotomy | 1977 |
Characterization of adrenoceptors mediating positive inotropic responses in the ventricular myocardium of the dog.
Topics: Adrenergic beta-Antagonists; Animals; Clonidine; Desipramine; Dogs; Female; Heart Ventricles; Male; Methoxamine; Myocardial Contraction; Papaverine; Papillary Muscles; Phenylephrine; Phosphodiesterase Inhibitors; Receptors, Adrenergic; Reserpine; Sinoatrial Node; Stimulation, Chemical; Temperature | 1978 |
Mianserin--an analysis of its peripheral autonomic actions.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Dibenzazepines; Electric Stimulation; Male; Mianserin; Norepinephrine; Phenoxybenzamine; Phentolamine; Rats; Tyramine; Yohimbine | 1978 |
Regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors.
Topics: Adrenergic Fibers; Animals; Catecholamines; Clonidine; Desipramine; Dogs; Electric Stimulation; Heart; Hemodynamics; Isoproterenol; Norepinephrine; Phenoxybenzamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sotalol | 1977 |
Cocaine and desipramine antagonize the clonidine-induced inhibition of [3H]-noradrenaline release from the rat cerebral cortex [proceedings].
Topics: Animals; Cerebral Cortex; Clonidine; Cocaine; Desipramine; In Vitro Techniques; Male; Norepinephrine; Rats | 1979 |
The effect of acute and chronic desipramine and amitriptyline treatment on rat brain total 3methoxy-4-hydroxyphenylglycol.
Topics: Amitriptyline; Animals; Brain Chemistry; Clonidine; Desipramine; Drug Interactions; Glycols; Male; Methoxyhydroxyphenylglycol; Rats; Time Factors | 1978 |
Effects of phentolamine, phenoxybenzamine and desipramine on clonidine-induced blockade of cardiac acceleration in the dog.
Topics: Animals; Clonidine; Desipramine; Dogs; Drug Interactions; Electric Stimulation; Female; Heart; Heart Rate; Male; Phenoxybenzamine; Phentolamine; Time Factors | 1977 |
Effect of clonidine on blood pressure, heart rate and body temperature in conscious rats.
Topics: Anesthesia; Animals; Atropine; Blood Pressure; Body Temperature; Chlorpromazine; Clonidine; Desipramine; Drug Synergism; Guanethidine; Heart Rate; Hexamethonium Compounds; Injections, Intravenous; Injections, Subcutaneous; Male; Phentolamine; Rats; Reserpine | 1977 |
The reversal of clonidine-induced hypotension by protriptyline and desipramine.
Topics: Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dibenzocycloheptenes; Female; Male; Protriptyline | 1976 |
Peripherally and centrally mediated bradycardiac effects of clonidine in anesthetized or spinal rats.
Topics: Animals; Blood Pressure; Clonidine; Desipramine; Electric Stimulation; Heart Rate; Male; Parasympatholytics; Rats; Sympathetic Nervous System; Sympatholytics; Sympathomimetics | 1976 |
Interaction between centrally acting hypotensive drugs and tricyclic antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Cats; Clonidine; Cocaine; Desipramine; Dioxanes; Drug Interactions; Ephedrine; Female; Male; Methyldopa; Piperidines; Reserpine | 1975 |
Reversal of the 6-hydroxydopamine-induced suppression of a CAR by drugs facilitating central catecholaminergic mechanisms.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Catecholamines; Clonidine; Desipramine; Hydroxydopamines; Injections, Intraventricular; Levodopa; Male; Norepinephrine; Phenelzine; Rats | 1975 |
Antagonism of antihypertensive effect of clonidine by imipramine & desmethylimipramine in renal hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Desipramine; Hypertension, Renal; Imipramine; Rats | 1975 |
ACTH accelerates the attenuation of alpha 2-adrenoceptors response in nucleus accumbens following chronic desipramine.
Topics: Adrenocorticotropic Hormone; Animals; Clonidine; Desipramine; Dopamine; Drug Interactions; Male; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tritium | 1992 |
Long-term downregulation of central adrenoceptor function by desipramine treatment: a clonidine study in normal subjects.
Topics: Adult; Clonidine; Depressive Disorder; Desipramine; Down-Regulation; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Male; Receptors, Adrenergic, alpha | 1992 |
Blunting growth hormone release in mania.
Topics: Bipolar Disorder; Clonidine; Desipramine; Growth Hormone; Humans; Receptors, Adrenergic, alpha | 1992 |
Long term treatment with desipramine increases the turnover of alpha 2-adrenoceptors in the rat brain.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Desipramine; Male; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1992 |
Subclassification of release-regulating alpha 2-autoreceptors in human brain cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Aged; Calcium; Cerebral Cortex; Clonidine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Oxymetazoline; Receptors, Adrenergic, alpha; Tetrodotoxin | 1992 |
Neuroendocrine response to clonidine and 8-OH-DPAT in rats following chronic administration of desipramine or sertraline.
Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cerebral Cortex; Clonidine; Corticosterone; Desipramine; Dihydroalprenolol; Male; Neurosecretory Systems; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sertraline; Tetrahydronaphthalenes | 1992 |
Effects of long-term desipramine administration on noradrenergic neurotransmission: electrophysiological studies in the rat brain.
Topics: Animals; Brain; Clonidine; Desipramine; Drug Administration Schedule; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Locus Coeruleus; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Synaptic Transmission | 1991 |
Determination of the role of noradrenergic and 5-hydroxytryptaminergic neurones in postsynaptic alpha 2-adrenoceptor desensitization by desipramine and ECS.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Clonidine; Desipramine; Down-Regulation; Electroshock; Male; Mice; Mice, Inbred Strains; Neurons; Norepinephrine; Pupil; Receptors, Adrenergic, alpha; Serotonin | 1991 |
[Effect of chronic desipramine treatment on rat brain adrenergic alpha 2-receptor].
Topics: Animals; Biogenic Monoamines; Brain; Brain Chemistry; Clonidine; Desipramine; Male; Methoxyhydroxyphenylglycol; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Clonidine causes antidepressant-like effects in rats by activating alpha 2-adrenoceptors outside the locus coeruleus.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Clonidine; Desipramine; Dioxanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydroxydopamines; Idazoxan; Locus Coeruleus; Male; Neurons; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Desipramine lowers tritiated para-aminoclonidine binding in platelets of depressed patients.
Topics: Adrenergic alpha-Agonists; Biomarkers; Blood Platelets; Cell Membrane; Clonidine; Depressive Disorder; Desipramine; Down-Regulation; Humans; Ligands; Receptors, Adrenergic, alpha; Tritium; Up-Regulation | 1991 |
Relationship between membrane fluidity and adrenoceptor binding in depression.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Diphenylhexatriene; Female; Fluorescence Polarization; Humans; Male; Membrane Fluidity; Middle Aged; Psychiatric Status Rating Scales; Radioligand Assay; Receptors, Adrenergic, alpha | 1991 |
Alpha-adrenoceptor blocking properties of vesamicol.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Electric Stimulation; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stereoisomerism; Vas Deferens | 1991 |
Secretion of growth hormone elicited by intravenous desipramine in the conscious, unrestrained rat.
Topics: Animals; Clonidine; Corticosterone; Desipramine; Dioxanes; Growth Hormone; Hypothalamo-Hypophyseal System; Idazoxan; Injections, Intravenous; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Desipramine enhances isolation-induced aggressive behavior in mice.
Topics: Aggression; Animals; Clonidine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Phentolamine; Prazosin; Social Isolation; Yohimbine | 1991 |
Lack of neuronal adaptive changes following chronic treatments in perinatally undernourished rats.
Topics: Adaptation, Physiological; Animals; Apomorphine; Clonidine; Desipramine; Female; Motor Activity; Neurons; Nutrition Disorders; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Restraint, Physical; Stress, Psychological | 1990 |
In vivo assessment of napamezole, an alpha-2 adrenoceptor antagonist and monoamine re-uptake inhibitor.
Topics: Adrenergic alpha-Antagonists; Animals; Blepharoptosis; Brain; Clonidine; Conditioning, Operant; Desipramine; Drug Interactions; Imidazoles; Imipramine; Male; Mice; Norepinephrine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Tetrabenazine | 1990 |
Noradrenaline reuptake and plasma dihydroxyphenylglycol during sustained changes in sympathetic activity in rabbits.
Topics: Animals; Blood Pressure; Brain; Clonidine; Desipramine; Heart Rate; Injections; Injections, Intravenous; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rabbits; Sympathetic Nervous System; Time Factors; Yohimbine | 1991 |
The importance of plasma 3,4-dihydroxyphenylglycol (DOPEG) in analyses of the sympathetic nervous system in vivo.
Topics: Adolescent; Adult; Aged; Animals; Clonidine; Desipramine; Female; Humans; Hypertension; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Rabbits; Sympathetic Nervous System; Synapses; Yohimbine | 1990 |
Chronic antidepressant and clonidine treatment effects on conflict behavior in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Clonidine; Conflict, Psychological; Desipramine; Female; Mianserin; Panic; Propiophenones; Rats; Rats, Inbred Strains; Time Factors; Trazodone | 1990 |
An investigation of the role of 5-hydroxytryptamine in the attenuation of presynaptic alpha 2-adrenoceptor-mediated responses by antidepressant treatments.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents; Biogenic Monoamines; Brain Chemistry; Clonidine; Desipramine; Electroshock; Fenclonine; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Adrenergic, alpha | 1990 |
In vivo measurement of noradrenaline and 3,4-dihydroxyphenylethyleneglycol in the rat hypothalamus by microdialysis: effects of various drugs affecting noradrenaline metabolism.
Topics: Animals; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Dialysis; Electrochemistry; Extracellular Space; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Mianserin; Microchemistry; Norepinephrine; Rats; Rats, Inbred Strains; Tetrodotoxin; Yohimbine | 1990 |
Studies on the role of alpha 2-adrenoceptors in the control of synaptosomal [3H]5-hydroxytryptamine release: effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzylamines; Cerebral Cortex; Citalopram; Clonidine; Clorgyline; Desipramine; Hydroxyindoleacetic Acid; Male; Maprotiline; Nomifensine; Potassium; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Synaptosomes; Yohimbine | 1986 |
Effect of long-term rolipram administration on the sensitivity of alpha 2-adrenoceptors in rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Clonidine; Desipramine; Drug Administration Schedule; Locomotion; Male; Phosphodiesterase Inhibitors; Pyrimidines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Rolipram | 1988 |
Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment.
Topics: Aging; Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Hydroxyindoleacetic Acid; Imipramine; Ketanserin; Kinetics; Male; Paroxetine; Piperidines; Prazosin; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Time Factors | 1988 |
Sex-related differences in central adrenergic function and responsiveness to repeated administration of desipramine or electroconvulsive shock.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Electroshock; Estrus; Female; Male; Motor Activity; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sex Factors; Sympathetic Nervous System | 1989 |
Increased 3H-clonidine binding in the platelets of patients with depressive and schizophrenic disorders.
Topics: Bipolar Disorder; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Humans; Imidazoline Receptors; Lithium; Psychiatric Status Rating Scales; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Schizophrenia; Trifluoperazine | 1989 |
Modulation of noradrenaline release from cat cerebral arteries by presynaptic alpha 2-adrenoceptors. Effect of chronic treatment with desipramine and cocaine.
Topics: Animals; Azepines; Cerebral Arteries; Clonidine; Cocaine; Desipramine; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Receptors, Adrenergic, alpha; Tetrodotoxin | 1989 |
A functional study of the development of the cardiac sympathetic neuroeffector junction in the SHR.
Topics: Aging; Animals; Blood Pressure; Clonidine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Neuroeffector Junction; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathetic Nervous System | 1989 |
Estimation of pA2 values at presynaptic alpha 2-autoreceptors in rabbit and rat brain cortex in the absence of autoinhibition.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Female; Idazoxan; In Vitro Techniques; Kinetics; Male; Nordefrin; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synapses; Yohimbine | 1989 |
The effects of acute and chronic desipramine on the thermogenic and hypoactivity responses to alpha 2-agonists in reserpinized and normal mice.
Topics: Adrenergic alpha-Agonists; Animals; Body Temperature Regulation; Brimonidine Tartrate; Clonidine; Desipramine; Female; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Quinoxalines; Reserpine | 1989 |
Differential effects of dopaminergic drugs on open-field behavior of spontaneously hypertensive rats and normotensive Wistar-Kyoto rats.
Topics: Amphetamine; Animals; Apomorphine; Benzazepines; Clonidine; Desipramine; Dopamine; Dopamine Agents; Haloperidol; Hypertension; Male; Motor Activity; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
Uptake inhibitors do not change the effect of imidazoline alpha 2-adrenoceptor agonists on transmitter release evoked by single pulse stimulation in mouse vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Cocaine; Desipramine; Imidazoles; In Vitro Techniques; Male; Mice; Muscle, Smooth; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Normetanephrine; Phenethylamines; Vas Deferens; Yohimbine | 1989 |
Adaptive changes in alpha-2 adrenoceptor mediated responses: analgesia, hypothermia and hypoactivity.
Topics: Adaptation, Physiological; Adrenergic alpha-Agonists; Analgesia; Animals; Body Temperature; Brain Chemistry; Clonidine; Desipramine; Dose-Response Relationship, Drug; Guanfacine; Guanidines; Hypnotics and Sedatives; Hypothermia, Induced; Male; Motor Activity; Phenylacetates; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1989 |
The influence of L-triiodothyronine (T3) on the effects of repeated administration of desipramine or electroconvulsive shock on alpha 2- and beta-adrenoceptor function in the brain of the rat: implications for the potentiation of antidepressant therapy by
Topics: Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Dioxanes; Electroshock; Idazoxan; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Triiodothyronine | 1987 |
Presynaptic autoinhibition of central noradrenaline release in vitro: operational characteristics and effects of drugs acting at alpha-2 adrenoceptors in the presence of uptake inhibition.
Topics: Animals; Brain; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Tritium | 1988 |
The influence of injection of oestradiol to female rats on changes in alpha 2- and beta-adrenoceptor function induced by repeated administration of desipramine or electroconvulsive shock.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Clonidine; Desipramine; Electroconvulsive Therapy; Estradiol; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1988 |
Supersensitivity of alpha 2-adrenoceptors modulating [3H]5-HT release after noradrenergic denervation with DSP4.
Topics: Adrenergic alpha-Antagonists; Amines; Animals; Benzylamines; Clonidine; Desipramine; Dioxanes; Electric Stimulation; Hippocampus; Idazoxan; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Serotonin; Sympathectomy, Chemical | 1985 |
Measurement of endogenous noradrenaline release in the rat cerebral cortex in vivo by transcortical dialysis: effects of drugs affecting noradrenergic transmission.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Calcium; Cerebral Cortex; Clonidine; Desipramine; Dialysis; Dioxanes; Edetic Acid; Idazoxan; Male; Microchemistry; Norepinephrine; Rats; Rats, Inbred Strains | 1986 |
Dopamine1 receptor agonist and alpha-2 adrenoceptor antagonist effects of fenoldopam in rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Clonidine; Decerebrate State; Desipramine; Domperidone; Drug Interactions; Electric Stimulation; Electrophysiology; Female; Fenoldopam; Male; Norepinephrine; Pulmonary Artery; Rabbits; Receptors, Dopamine; Sympathetic Nervous System | 1986 |
Super high affinity 3H-para-aminoclonidine binding to platelet adrenoceptors in depression.
Topics: Adrenergic alpha-Agonists; Adult; Blood Platelets; Clonidine; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Radioligand Assay; Receptors, Adrenergic, alpha | 1988 |
Effects of clonidine on the stimulation-evoked release of 3H-noradrenaline from superfused rat brain slices as a function of the biophase concentration. Temperature dependent widening of extracellular space.
Topics: Animals; Brain; Clonidine; Desipramine; Electric Stimulation; Extracellular Space; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Polyethylene Glycols; Potassium; Rats; Rats, Inbred Strains; Temperature | 1986 |
Clonidine stimulation in anorexia nervosa: growth hormone, cortisol, and beta-endorphin responses.
Topics: Adolescent; Adult; Anorexia Nervosa; beta-Endorphin; Clonidine; Desipramine; Endorphins; Female; Growth Hormone; Humans; Hydrocortisone | 1987 |
Neuronal and postjunctional components in the blood pressure effects of dopamine and bromocriptine in rabbits.
Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Bromocriptine; Clonidine; Decerebrate State; Desipramine; Domperidone; Dopamine; Female; Male; Neurons; Nitroprusside; Norepinephrine; Propranolol; Rabbits; Receptors, Dopamine; Receptors, Neurotransmitter | 1985 |
(Na+,K+)-ATPase and noradrenergic regulation: effects of cardiac glycoside treatment and noradrenergic manipulations.
Topics: Animals; Benzylamines; Brain; Cardiac Glycosides; Clonidine; Desipramine; Digitoxin; Dihydroalprenolol; Kidney; Male; Methoxyhydroxyphenylglycol; Myocardium; Norepinephrine; Ouabain; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase; Yohimbine | 1985 |
Clorgyline and desipramine alter the sensitivity of [3H]noradrenaline release to calcium but not to clonidine.
Topics: Animals; Calcium; Cerebral Cortex; Clonidine; Clorgyline; Desipramine; Drug Interactions; Male; Norepinephrine; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes | 1986 |
Pharmacologic evidence that high dose chronic amitriptyline and desipramine down-regulate alpha 2-receptor-mediated hypothermia in the rat.
Topics: Amitriptyline; Animals; Body Temperature Regulation; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Half-Life; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Neuroendocrine and other studies of the mechanism of antidepressant action of desipramine.
Topics: Animals; Blood Pressure; Clonidine; Depression; Desipramine; Growth Hormone; Humans; Melatonin; Phenylephrine; Pupil; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Secretory Rate; Synaptic Transmission; Tyramine | 1986 |
Effects of antidepressant drug treatments on alpha 2-adrenoceptor control of [3H]noradrenaline release from hypothalamic synaptosomes.
Topics: Animals; Antidepressive Agents; Clonidine; Clorgyline; Desipramine; Hypothalamus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes; Yohimbine | 1987 |
Neuroendocrine measures in anorexia nervosa: comparisons with primary affective disorders.
Topics: Adolescent; Adult; Anorexia Nervosa; beta-Endorphin; beta-Lipotropin; Circadian Rhythm; Clonidine; Depressive Disorder; Desipramine; Dexamethasone; Endorphins; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Norepinephrine; Pituitary-Adrenal System; Receptors, Adrenergic | 1987 |
[3H]adrenaline release from hypothalamic synaptosomes and its modulation by clonidine: effects of chronic antidepressant drug regimens.
Topics: Animals; Antidepressive Agents; Cerebral Cortex; Clonidine; Clorgyline; Desipramine; Epinephrine; Hypothalamus; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Synaptosomes | 1987 |
Effect of chronic desipramine treatment on neurotransmitter-thyrotropin releasing hormone--thyrotropin interactions in the rat.
Topics: Animals; Clonidine; Desipramine; Drug Interactions; Isoproterenol; Male; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Thyrotropin; Thyrotropin-Releasing Hormone | 1987 |
Cocaine-elicited mydriasis in the rat: pharmacological comparison to clonidine, D-amphetamine and desipramine.
Topics: Animals; Catecholamines; Clonidine; Cocaine; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Injections, Intraventricular; Pupil; Rats; Rats, Inbred Strains; Reserpine | 1988 |
Characterization of hippocampal norepinephrine release as measured by microdialysis perfusion: pharmacological and behavioral studies.
Topics: Animals; Clonidine; Desipramine; Hippocampus; Male; Norepinephrine; Perfusion; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Yohimbine | 1988 |
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium.
Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans.
Topics: Administration, Oral; Adult; Body Fluids; Clonidine; Desipramine; Female; Glycols; Humans; Infusions, Intravenous; Intracellular Fluid; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Supination; Yohimbine | 1988 |
Behavioural and neuropharmacological properties of the dibenzazepines, desipramine and lofepramine: studies on the olfactory bulbectomized rat model of depression.
Topics: Animals; Arousal; Avoidance Learning; Behavior, Animal; Clonidine; Depressive Disorder; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Exploratory Behavior; Lofepramine; Male; Motor Activity; Olfactory Bulb; Rats; Rats, Inbred Strains; Smell | 1988 |
Electrophysiological effects of methylphenidate on the coeruleo-cortical noradrenergic system in the rat.
Topics: Animals; Behavior, Animal; Clonidine; Desipramine; Electric Stimulation; Electrophysiology; Iontophoresis; Locus Coeruleus; Male; Methylphenidate; Neurons; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
Antipanic drug effects during lactate infusion in lactate-refractory panic patients.
Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Desipramine; Fear; Female; Fluoxetine; Humans; Imipramine; Lactates; Lactic Acid; Male; Panic; Phobic Disorders; Psychological Tests; Psychotropic Drugs | 1987 |
Acute and chronic effects of desipramine administration to rhesus monkeys.
Topics: Animals; Clonidine; Desipramine; Drug Interactions; Kinetics; Macaca mulatta; Male; Methoxyhydroxyphenylglycol; Norepinephrine | 1987 |
Effect of chronic administration of alprazolam and adinazolam on clonidine- or apomorphine-induced aggression in laboratory rodents.
Topics: Aggression; Alprazolam; Animals; Anti-Anxiety Agents; Apomorphine; Benzodiazepines; Clonidine; Desipramine; Diazepam; Drug Interactions; Male; Mice; Rats; Rats, Inbred Strains | 1986 |
Behavioral depression following clonidine withdrawal: a new animal model of long-lasting depression?
Topics: Animals; Clonidine; Depressive Disorder; Desipramine; Disease Models, Animal; Rats; Substance Withdrawal Syndrome | 1986 |
Desipramine binding: relationship to central and sympathetic noradrenergic activity.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dextroamphetamine; Heart; Hydroxydopamines; Isoproterenol; Male; Muscles; Norepinephrine; Oxidopamine; Prazosin; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synapses | 1985 |
Neuropharmacological modification of central catecholamines: effects on pinealectomy-induced convulsions.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catecholamines; Clonidine; Desipramine; Levodopa; Male; Methyltyrosines; Parathyroid Glands; Pineal Gland; Rats; Reserpine; Seizures; Timolol | 1986 |
Accumulation of 3H-adrenaline by rabbit aorta.
Topics: Animals; Aorta; Catechol O-Methyltransferase Inhibitors; Clonidine; Cocaine; Desipramine; Epinephrine; Hypoxia; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Ouabain; Propranolol; Rabbits; Radionuclide Imaging; Tritium | 1985 |
Long-term desipramine treatment attenuates clonidine-induced suppression of ventral tegmental self-stimulation.
Topics: Animals; Clonidine; Desipramine; Electric Stimulation; Male; Rats; Rats, Inbred Strains; Self Stimulation; Tegmentum Mesencephali; Time Factors | 1985 |
Effect of chronic desipramine treatment on adrenoceptor modulation of [3H]dopamine release from rat nucleus accumbens slices.
Topics: Animals; Calcium; Clonidine; Desipramine; Dopamine; Drug Interactions; In Vitro Techniques; Isoproterenol; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Septal Nuclei | 1985 |
Drug-induced changes in the release of 3 H-monoamines from field stimulated rat brain slices.
Topics: Adrenergic Agents; Animals; Antihypertensive Agents; Apomorphine; Central Nervous System; Cerebral Cortex; Clonidine; Cocaine; Desipramine; Dibenzazepines; Dopamine; Electric Stimulation; Feedback; Female; Imidazoles; Lysergic Acid Diethylamide; Methods; Neurons; Norepinephrine; Rats; Sensory Receptor Cells; Serotonin; Stimulation, Chemical; Synaptic Transmission; Time Factors; Tritium | 1971 |
Influence of alpha- and beta-adrenoceptors on the release of noradrenaline from field stimulated atria and cerebral cortex slices.
Topics: Animals; Atrial Function; Cerebral Cortex; Clonidine; Desipramine; Electric Stimulation; Guanidines; Heart Atria; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred Strains; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Receptors, Adrenergic | 1974 |
The cardiovascular effects of intraventricular clonidine and Bay 1470 in conscious hypertensive cats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dioxanes; Dopamine Antagonists; Haloperidol; Heart Rate; Hemodynamics; Hypertension, Renal; Phentolamine; Piperidines; Thiazines; Time Factors; Xylazine | 1974 |
Desmethylimipramine and the hypotensive action of clonidine in the rabbit.
Topics: Animals; Blood Pressure; Clonidine; Desipramine; Rabbits | 1972 |
Desmethylimipramine and the hypotensive action of clonidine in the rabbit.
Topics: Animals; Blood Pressure; Cisterna Magna; Clonidine; Desipramine; Heart Rate; Injections; Injections, Intravenous; Male; Norepinephrine; Rabbits; Time Factors | 1973 |
Chronic decentralization prevents alpha-receptor mediated regulation of noradrenaline release in the field stimulated rat iris.
Topics: Animals; Clonidine; Denervation; Desipramine; Electric Stimulation; Female; Ganglia, Autonomic; Iris; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Synapses; Time Factors; Tritium | 1973 |
The interference of tricyclic antidepressants with the central hypotensive effect of clonidine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Cats; Clonidine; Desipramine; Imipramine; Time Factors | 1973 |
Effects of desipramine treatment upon central adrenoceptor function in normal subjects.
Topics: Adult; Blood Pressure; Clonidine; Depression, Chemical; Desipramine; Growth Hormone; Humans; Hypnotics and Sedatives; Male; Receptors, Adrenergic, alpha; Time Factors | 1984 |
Behavioral evidence for alpha 1-adrenoceptor up- and alpha 2-adrenoceptor down-regulation in the rat hippocampus after chronic desipramine treatment.
Topics: Animals; Behavior, Animal; Clonidine; Desipramine; Hippocampus; Isoproterenol; Male; Microinjections; Motor Activity; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Adrenergic-receptor desensitization and course of clinical improvement with desipramine treatment.
Topics: Adult; Blood Pressure; Clonidine; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Receptors, Adrenergic, alpha; Time Factors | 1984 |
Effects of chronic desipramine treatment on rat brain noradrenergic responses to alpha-adrenergic drugs.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brain Chemistry; Clonidine; Desipramine; Drug Interactions; Electroencephalography; Female; Locus Coeruleus; Norepinephrine; Rats | 1980 |
Neuronal responses of the globus pallidus to systemic administration of d-amphetamine: investigation of the involvement of dopamine, norepinephrine, and serotonin.
Topics: alpha-Methyltyrosine; Animals; Clonidine; Desipramine; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Globus Pallidus; Haloperidol; Male; Methyltyrosines; Neurons; Norepinephrine; Rats; Serotonin; Tyrosine 3-Monooxygenase | 1981 |
Evidence for a physiological role of presynaptic alpha-adrenoceptors: modulation of noradrenaline release in the pithed rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Desipramine; Electric Stimulation; Epinephrine; Female; Guanethidine; Heart Rate; Male; Nordefrin; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spinal Nerves; Yohimbine | 1983 |
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidine; Clozapine; Depressive Disorder; Desipramine; Dibenzazepines; Haloperidol; Humans; Male; Metoclopramide; Phentolamine; Prazosin; Propranolol; Rats; Sulpiride | 1984 |
Effects of adrenoceptor antagonists and neuronal uptake inhibitors on dimethylphenylpiperazinium-induced release of catecholamines from the rabbit isolated adrenal gland and guinea-pig atria.
Topics: Adrenal Glands; Adrenergic alpha-Antagonists; Animals; Catecholamines; Clonidine; Cocaine; Desipramine; Dimethylphenylpiperazinium Iodide; Epinephrine; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Myocardium; Neurotransmitter Uptake Inhibitors; Phentolamine; Piperazines; Propranolol; Rabbits; Sympatholytics; Tritium | 1984 |
Is there a functional linkage between neurotransmitter uptake mechanisms and presynaptic receptors?
Topics: Acetylcholine; Animals; Clomipramine; Clonidine; Cocaine; Desipramine; Dopamine; Hemicholinium 3; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Nomifensine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Synaptosomes | 1984 |
Active metabolites of antidepressants: pharmacodynamics and relevant pharmacokinetics.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Asian People; Biotransformation; Clonidine; Desipramine; Female; Humans; Hydroxyindoleacetic Acid; Imipramine; Kinetics; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Serotonin; Structure-Activity Relationship; White People | 1984 |
Comparison of mianserin with desipramine, maprotiline and phentolamine on cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors and noradrenaline reuptake in pithed normotensive rats.
Topics: Animals; Anthracenes; Blood Vessels; Cardiovascular System; Clonidine; Desipramine; Dibenzazepines; Drug Interactions; Heart; Male; Maprotiline; Mianserin; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord | 1980 |
Feedback control of noradrenaline release as a function of noradrenaline concentration in the synaptic cleft in cortical slices of the rat.
Topics: Animals; Cerebral Cortex; Clonidine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Feedback; Male; Neural Inhibition; Norepinephrine; Piperoxan; Rats; Receptors, Adrenergic, alpha; Synapses | 1980 |
Inhibition of neuronal uptake reduces the presynaptic effects of clonidine but not of alpha-methylnoradrenaline on the stimulation-evoked release of 3H-noradrenaline from rat occipital cortex slices.
Topics: Amphetamine; Animals; Cerebral Cortex; Clonidine; Cocaine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Nordefrin; Norepinephrine; Pargyline; Phentolamine; Rats; Receptors, Adrenergic, alpha; Tritium | 1980 |
Effects of desipramine and yohimbine on alpha 2- and beta-adrenoreceptor sensitivity.
Topics: Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Male; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors; Yohimbine | 1980 |
Evaluation of presynaptic alpha-receptor function in the canine renal vascular bed.
Topics: Animals; Cattle; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Antagonism; Epinephrine; Female; Kidney; Male; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasomotor System; Yohimbine | 1980 |
Functional evidence for subsensitivity of noradrenergic alpha 2 receptors after chronic desipramine treatment.
Topics: Animals; Clonidine; Desipramine; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
A pilot study of the mechanism of action of desipramine.
Topics: Adult; Aged; Blood Pressure; Clonidine; Depressive Disorder; Desipramine; Drug Interactions; Female; Humans; Male; Middle Aged; Pilot Projects; Receptors, Adrenergic, alpha | 1981 |
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Desipramine; Humans; In Vitro Techniques; Iprindole; Kinetics; Male; Mianserin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Presynaptic adrenergic receptor sensitivity in depression. The effect of long-term desipramine treatment.
Topics: Adult; Aged; Blood Pressure; Brain; Clonidine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Psychiatric Status Rating Scales; Pulse; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Interaction between mianserin and clonidine at alpha 2-adrenoceptors.
Topics: Animals; Blood Pressure; Chickens; Clonidine; Desipramine; Dibenzazepines; Dogs; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Heart; Heart Rate; Ileum; In Vitro Techniques; Male; Mianserin; Morphine; Muscle Contraction; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sleep | 1982 |
Effect of chronic antidepressants on rat brain alpha 2-adrenoceptor sensitivity.
Topics: Animals; Antidepressive Agents; Brain; Clonidine; Desipramine; Male; Methoxyhydroxyphenylglycol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Time Factors | 1982 |
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine | 1982 |
A study of the sensitivity of rat brain alpha 2-adrenoceptors during chronic antidepressant treatments.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Cerebral Cortex; Clonidine; Desipramine; Dihydroalprenolol; Electroshock; Male; Methoxyhydroxyphenylglycol; Pargyline; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Tricyclic antidepressants vary in decreasing alpha 2-adrenoceptor sensitivity with chronic treatment: assessment with clonidine inhibition of acoustic startle.
Topics: Animals; Antidepressive Agents, Tricyclic; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex, Startle; Time Factors | 1982 |
The effect of desipramine upon central adrenergic function in depressed patients.
Topics: Adult; Blood Pressure; Clonidine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Male; Middle Aged; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1982 |
Effects of (+)- and (-)-mianserin on alpha-adrenoceptors and tyramine-induced tachycardia in rats.
Topics: Animals; Blood Pressure; Clonidine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Heart Rate; Male; Methoxamine; Mianserin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Stereoisomerism; Tyramine | 1983 |
Changes in the sensitivity of the central alpha- and beta-adrenergic systems during desmethylimipramine treatment as assessed by plasma growth hormone response in the baboon.
Topics: Animals; Brain; Clonidine; Desipramine; Female; Growth Hormone; Humans; Male; Papio; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Substance Withdrawal Syndrome | 1983 |
On the role of brain alpha-adrenergic systems in the production of paradoxical sleep.
Topics: Animals; Chlorpromazine; Clonidine; Desipramine; Male; Phenoxybenzamine; Piperoxan; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Secologanin Tryptamine Alkaloids; Sleep, REM | 1982 |
The effects of acute and repeated administration of various antidepressant drugs on clonidine-induced hypoactivity in mice and rats.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clonidine; Desipramine; Male; Mianserin; Mice; Mice, Inbred C57BL; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1983 |
A study of the effects of clonidine on the EEG in rats treated with single and multiple doses of antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clonidine; Desipramine; Electroencephalography; Male; Mianserin; Rats; Rats, Inbred Strains | 1984 |
Noradrenaline uptake inhibitors do not reduce the presynaptic action of clonidine on 3H-noradrenaline release in superfused synaptosomes.
Topics: Animals; Clonidine; Cocaine; Desipramine; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1984 |
Catecholamine metabolism in the rat locus coeruleus as studied by in vivo differential pulse voltammetry. II. Pharmacological and behavioral study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Clonidine; Desipramine; Haloperidol; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Piperoxan; Rats; Reserpine; Stress, Physiological | 1983 |
Further studies on the suppressing effect of isoproterenol on the immobility-reducing action of desipramine in the forced swimming test.
Topics: Animals; Atenolol; Clonidine; Desipramine; Isoproterenol; Male; Motor Activity; Phenylephrine; Rats; Rats, Inbred Strains; Swimming; Yohimbine | 1983 |
Lactate provocation of panic attacks. I. Clinical and behavioral findings.
Topics: Adult; Agoraphobia; Anxiety Disorders; Clonidine; Desipramine; Fear; Female; Humans; Imipramine; Lactates; Lactic Acid; Male; Panic | 1984 |
Differential effect of chronic desipramine and amitriptyline treatment on rat brain adrenergic and serotonergic receptors.
Topics: Amitriptyline; Animals; Brain; Cerebral Cortex; Clonidine; Desipramine; Dihydroalprenolol; Dioxanes; Male; Radioligand Assay; Rats; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Spiperone | 1981 |
Failure of chronic antidepressant treatment to alter growth hormone response to clonidine.
Topics: Amitriptyline; Clonidine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Growth Hormone; Humans; Male; Middle Aged | 1982 |
Effects of acutely and chronically administered antidepressants on the clonidine-induced decrease in rat brain 3-methoxy-4-hydroxyphenylethylene-glycol sulphate content.
Topics: Animals; Antidepressive Agents; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Desipramine; Fluoxetine; Glycols; Iprindole; Male; Methoxyhydroxyphenylglycol; Mianserin; Rats | 1981 |
The effects of acute and repeated treatment with salbutamol, a beta-adrenoceptor agonist, on clonidine-induced hypoactivity in rats.
Topics: Albuterol; Animals; Clonidine; Desipramine; Drug Interactions; Exploratory Behavior; Fluoxetine; Imipramine; Male; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
[Central hypotensive effects of guanfacine in anaesthetised rabbits (author's transl)].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Desipramine; Guanfacine; Guanidines; Heart Rate; Hydroxydopamines; Injections, Intravenous; Injections, Intraventricular; Phentolamine; Phenylacetates; Rabbits | 1982 |
Attention and habituation: catecholamine interactions and sex differences.
Topics: Animals; Attention; Catecholamines; Clonidine; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Female; Gerbillinae; Habituation, Psychophysiologic; Male; Odorants; Sex Factors | 1982 |
Effects of noradrenergic neuronal activity on 3,4-dihydroxyphenylethylene glycol (DHPG) levels. Quantitation by high performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Female; Glycols; Methoxyhydroxyphenylglycol; Myocardium; Nerve Endings; Norepinephrine; Rabbits; Sympathetic Nervous System; Tranylcypromine | 1982 |
Mescaline and LSD facilitate the activation of locus coeruleus neurons by peripheral stimuli.
Topics: Amphetamine; Animals; Clonidine; Desipramine; Electric Conductivity; Locus Coeruleus; Lysergic Acid Diethylamide; Male; Mescaline; Neurons; Rats; Sciatic Nerve | 1980 |
Clonidine: attenuation of sedative action by facilitated central noradrenergic neurotransmission.
Topics: Amphetamine; Animals; Brain; Clonidine; Desipramine; Dihydroxyphenylalanine; Female; Hydrazines; Learning; Mice | 1980 |
Local influence of endogenous norepinephrine on extracellular dopamine in rat medial prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clonidine; Desipramine; Dioxanes; Dopamine; Dopamine Uptake Inhibitors; Electroshock; Extracellular Space; Idazoxan; Male; Microdialysis; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 1995 |
Antidepressant and depressogenic drugs lack consistent effects on hamster circadian rhythms.
Topics: Animals; Antidepressive Agents; Arousal; Circadian Rhythm; Clonidine; Clorgyline; Cricetinae; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Male; Mesocricetus; Motor Activity; Phenelzine; Propranolol | 1994 |
Effect of desipramine-induced blockade of neuronal uptake mechanisms on adrenoceptor-mediated responses in the guinea-pig colon.
Topics: Acetylcholine; Adrenergic Agonists; Animals; Clonidine; Colon; Desipramine; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Neurons; Norepinephrine; Peristalsis; Phenylephrine; Receptors, Adrenergic; Xylazine | 1994 |
Desipramine-induced increase in norepinephrine transporter mRNA is not mediated via alpha 2 receptors.
Topics: Animals; Carrier Proteins; Clonidine; Desipramine; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; RNA, Messenger; Symporters; Yohimbine | 1994 |
In vivo noradrenaline release evoked in the anteroventral thalamic nucleus by locus coeruleus activation: an electrochemical study.
Topics: Animals; Axons; Clonidine; Desipramine; Electric Stimulation; Electrochemistry; Evoked Potentials; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Norepinephrine; Oxidation-Reduction; Pargyline; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thalamic Nuclei; Yohimbine | 1993 |
In vivo electrophysiological evidence for tonic activation by endogenous noradrenaline of alpha 2-adrenoceptors on 5-hydroxytryptamine terminals in the rat hippocampus.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Desipramine; Electrophysiology; Hippocampus; Male; Nerve Endings; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Serotonin | 1993 |
Effects of clonidine on desipramine- and desmethylclomipramine-induced 3-methoxy-4-hydroxyphenylglycol levels in rat brain.
Topics: Animals; Brain; Clomipramine; Clonidine; Desipramine; Drug Interactions; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Wistar | 1993 |
Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome.
Topics: Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Female; Humans; Male; Nortriptyline; Tourette Syndrome; Treatment Outcome | 1993 |
[Effects of desipramine and clomipramine on alpha 2-adrenergic receptor function in nucleus accumbens: studies with intracerebral dialysis in freely moving rats].
Topics: Adrenergic alpha-Agonists; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Clonidine; Desipramine; Dialysis; Male; Methoxyhydroxyphenylglycol; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 1995 |
In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies.
Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cerebral Cortex; Citalopram; Clonidine; Desipramine; Fluoxetine; Fluvoxamine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1996 |
Modelling the changes induced by chronic desipramine treatment on the factors governing the agonism at prejunctional alpha 2-adrenoceptors.
Topics: Adrenergic Uptake Inhibitors; Animals; Clonidine; Desipramine; Dose-Response Relationship, Drug; Logistic Models; Male; Models, Biological; Muscle, Smooth; Quinolines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vas Deferens; Xylazine | 1996 |
Long-term antidepressant treatment restores clonidine's effect on growth hormone secretion in a genetic animal model of depression.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clonidine; Clorgyline; Depressive Disorder; Desipramine; Female; Fluoxetine; Growth Hormone; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains | 1996 |
Dopamine, as well as norepinephrine, is a link between noradrenergic nerve terminals and splenocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Berberine; Clonidine; Desipramine; Dopamine; Dopamine Antagonists; Electric Stimulation; Male; Muscarinic Agonists; Norepinephrine; Oxotremorine; Presynaptic Terminals; Rats; Rats, Wistar; Spleen; Sulpiride; Sympathomimetics; Tritium | 1997 |
Effect of acute, short- and long-term milnacipran administration on rat locus coeruleus noradrenergic and dorsal raphe serotonergic neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Biological Transport; Brimonidine Tartrate; Clonidine; Cyclopropanes; Desipramine; Drug Administration Schedule; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Injections, Subcutaneous; Kinetics; Locus Coeruleus; Lysergic Acid Diethylamide; Male; Mesencephalon; Milnacipran; Neurons; Norepinephrine; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Spiperone; Time Factors | 1998 |
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice.
Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fentanyl; Lidocaine; Male; Mice; Morphine; Oxymetazoline; Pain; Pain Measurement; Pertussis Toxin; Temperature; Virulence Factors, Bordetella | 2000 |
The differential effects of calcium channel blockers in the behavioural despair test in mice.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; Depression; Desipramine; Diltiazem; Drug Interactions; Female; Male; Mianserin; Mice; Motor Activity; Nifedipine; Tranylcypromine; Verapamil | 2000 |
Chronic treatment with desipramine facilitates its effect on extracellular noradrenaline in the rat hippocampus: studies on the role of presynaptic alpha2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Clonidine; Desipramine; Dose-Response Relationship, Drug; Extracellular Space; Hippocampus; Idazoxan; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Presynaptic; Synaptosomes; Time Factors; Tritium | 2001 |
Modulation of MK-801-induced behaviour by noradrenergic agents in mice.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Ataxia; Benzylamines; Clonidine; Desipramine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Frontal Lobe; Male; Mesencephalon; Mice; Morpholines; Motor Activity; Norepinephrine; Prazosin; Reboxetine; Stereotyped Behavior | 2001 |
Acute and chronic effects of desipramine and clorgyline on alpha(2)-adrenoceptors regulating noradrenergic transmission in the rat brain: a dual-probe microdialysis study.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Brain; Clonidine; Clorgyline; Desipramine; Gyrus Cinguli; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Time Factors | 2001 |
Increased neuronal activity in locus coeruleus from adult rats undernourished at perinatal age: its reversal by desipramine.
Topics: Animals; Clonidine; Desipramine; Female; Locus Coeruleus; Models, Animal; Neurons; Nutrition Disorders; Pregnancy; Rats; Rats, Wistar | 2001 |
A morpholinocatechol compound (UK42620) with clonidine- and tyramine-like actions.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Cardiotonic Agents; Catechols; Clonidine; Desipramine; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Morpholines; Myocardial Contraction; Propranolol; Rats; Rats, Sprague-Dawley; Tyramine | 2001 |
Noradrenergic and serotonergic neuroendocrine responses in prepubertal, peripubertal, and postpubertal rats pretreated with desipramine and sertraline.
Topics: Animals; Clonidine; Desipramine; Dose-Response Relationship, Drug; Fenfluramine; Growth Hormone; Male; Neurosecretory Systems; Premedication; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Serotonin; Sertraline; Sexual Maturation | 2002 |
In the rat forced swimming test, chronic but not subacute administration of dual 5-HT/NA antidepressant treatments may produce greater effects than selective drugs.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Clonidine; Cyclopropanes; Depression; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Male; Mianserin; Milnacipran; Mirtazapine; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Swimming | 2002 |
Differential effects of K(ATP) channel blockers on [(3)H]-noradrenaline overflow after short- and long-term exposure to (+)-oxaprotiline or desipramine.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Autoreceptors; Clonidine; Desipramine; Drug Interactions; Glyburide; In Vitro Techniques; Male; Maprotiline; Neocortex; Norepinephrine; Potassium Channel Blockers; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
Mirtazapine-induced corelease of dopamine and noradrenaline from noradrenergic neurons in the medial prefrontal and occipital cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Clonidine; Desipramine; Dopamine; Injections, Intraperitoneal; Male; Mianserin; Microdialysis; Mirtazapine; Neurons; Norepinephrine; Occipital Lobe; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 2004 |
Autoreceptor-mediated inhibition of norepinephrine release in rat medial prefrontal cortex is maintained after chronic desipramine treatment.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Autoreceptors; Clonidine; Desipramine; Dose-Response Relationship, Drug; Extracellular Fluid; Male; Microdialysis; Norepinephrine; Potassium; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time; Yohimbine | 2004 |
An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Blotting, Northern; Brimonidine Tartrate; Clonidine; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Freezing Reaction, Cataleptic; Gene Expression Regulation; In Vitro Techniques; Male; Neural Inhibition; Norepinephrine; Quinoxalines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming; Time Factors; Tumor Necrosis Factor-alpha; Yohimbine | 2005 |
Critical involvement of dopaminergic neurotransmission in impulsive decision making.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Choice Behavior; Clonidine; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Impulsive Behavior; Male; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Reward | 2006 |
Nonstimulant medications for the treatment of ADHD.
Topics: Adrenergic alpha-Agonists; Antidepressive Agents, Tricyclic; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Desipramine; Humans; Propylamines; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors | 2006 |
Expression and functional characterization of choline transporter in human keratinocytes.
Topics: Acetylcholine; Anisoles; Antigens, CD; Biological Transport; Cell Membrane; Cells, Cultured; Choline; Clonidine; Desipramine; Diphenhydramine; Gene Expression Profiling; Humans; Keratinocytes; Membrane Potentials; Octamer Transcription Factor-3; Organic Cation Transport Proteins; p-Aminohippuric Acid; Quinidine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters; Tetraethylammonium; Time Factors; Tritium | 2009 |
Jugular venous overflow of noradrenaline from the brain: a neurochemical indicator of cerebrovascular sympathetic nerve activity in humans.
Topics: Adrenergic Uptake Inhibitors; Adult; Biomarkers; Case-Control Studies; Cerebral Arteries; Cerebral Veins; Cerebrovascular Circulation; Clonidine; Databases as Topic; Desipramine; Female; Ganglionic Blockers; Humans; Jugular Veins; Kinetics; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Predictive Value of Tests; Pure Autonomic Failure; Reference Values; Sympathetic Nervous System; Sympatholytics; Trimethaphan | 2009 |
On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists.
Topics: Adrenergic Agonists; Animals; Attention; Choice Behavior; Clenbuterol; Clonidine; Desipramine; Dobutamine; Dose-Response Relationship, Drug; Inhibition, Psychological; Isoproterenol; Male; Methylphenidate; Phenylephrine; Rats; Rats, Wistar; Reaction Time; Serial Learning | 2012 |
Regulation of CCL2/MCP-1 production in astrocytes by desipramine and atomoxetine: involvement of α2 adrenergic receptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; Animals; Astrocytes; Atomoxetine Hydrochloride; Cells, Cultured; Chemokine CCL2; Clonidine; Cyclic AMP; Desipramine; Isoproterenol; Norepinephrine; Propylamines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Yohimbine | 2011 |
The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Brimonidine Tartrate; Clonidine; Desipramine; Disease Models, Animal; Idazoxan; Locus Coeruleus; Male; MAP Kinase Signaling System; Medulla Oblongata; Neuralgia; Norepinephrine; Prefrontal Cortex; Quinoxalines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Signal Transduction; Spinal Cord | 2012 |
Morris water maze performance deficit produced by intermittent swim stress is partially mediated by norepinephrine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Clonidine; Desipramine; Hippocampus; Learning; Male; Maze Learning; Memory Disorders; Morpholines; Norepinephrine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reboxetine; Swimming | 2012 |
Removal of half the sympathetic innervation does not reduce vasoconstrictor responses in rat tail artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Desipramine; Idazoxan; Isometric Contraction; Muscle Denervation; Myocytes, Smooth Muscle; Neuromuscular Junction; Norepinephrine; Phenylephrine; Rats; Sympathetic Nervous System; Synaptic Potentials; Tail; Vasoconstriction | 2013 |
Novel technique to determine the pK
Topics: Animals; Clonidine; Cystamine; Desipramine; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Male; Mesenteric Arteries; Mice; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System; Synaptic Transmission; Yohimbine | 2017 |