desipramine has been researched along with clomipramine in 249 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 131 (52.61) | 18.7374 |
| 1990's | 67 (26.91) | 18.2507 |
| 2000's | 26 (10.44) | 29.6817 |
| 2010's | 23 (9.24) | 24.3611 |
| 2020's | 2 (0.80) | 2.80 |
| Authors | Studies |
|---|---|
| Carnmalm, B; Ogren, SO; Rämsby, S; Renyi, AL; Ross, SB | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Costanzo, MJ; Gardocki, JF; Maryanoff, BE; McComsey, DF; Nortey, SO; Schneider, CR; Setler, PE; Shank, RP | 1 |
| Bonnaud, B; Briley, M; Cousse, H; Couzinier, JP; Fauran, F; Mouzin, G; Stenger, A | 1 |
| Lucas, RA; Smith, RG; Wasley, JW | 1 |
| Chiang, GH; Unger, SH | 1 |
| Högberg, T; Renyi, AL; Ross, SB; Ulff, B | 1 |
| Anderson, VB; Geyer, HM; Kruse, H; Ong, HH; Profitt, JA; Wilker, JC | 1 |
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Choi, K; Moon, B; Park, JE; Roh, EJ; Sim, T; Song, C | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Nagy, A | 2 |
| Cohen, D; Weinstock, M | 1 |
| Fromm, GH; Glass, JD | 1 |
| Bechgaard, E; Buus Lassen, J; Lund, J; Søndergaard, I | 1 |
| Carruba, MO; Mantegazza, P; Parenti, M; Picotti, GB; Ricciardi, S | 1 |
| Segal, M | 1 |
| Carlsson, I; Lagerström, PO; Persson, BA | 1 |
| Gerschenfeld, HM; Hamon, M; Paupardin-Tritsch, D | 1 |
| Franz, DN; Sangdee, C | 1 |
| Ogren, SO; Ross, SB | 1 |
| Tseng, LF | 2 |
| Ueki, S; Yamamoto, T | 1 |
| Murphy, JE | 1 |
| Burgess, CD; Turner, P; Wadsworth, J | 1 |
| Caine, ED; Ebert, MH; Mikkelsen, EJ; Polinsky, RJ; Rapoport, JL | 1 |
| Ehsanullah, RS; Ghose, K; Kirby, MJ; Turner, P; Witts, D | 1 |
| Everitt, BJ | 1 |
| Korf, J; Meisch, JJ; van Wijk, M | 1 |
| Briley, M; Langer, SZ; Raisman, R | 1 |
| Alkalay, D; Carlsen, S; Volk, J | 1 |
| Calil, HM; Goodwin, FK; Manian, AA; Potter, WZ; Zavadil, AP | 1 |
| Albert, W; Klicpera, C; Strian, F | 1 |
| Astrachan, D; Davis, M; Sheard, M | 1 |
| Ogren, SO; Renyi, AL; Ross, SB | 2 |
| Huey, LY; Janowsky, DS; Risch, SC | 1 |
| Howarth, AT | 1 |
| Frommer, R; Yehuda, S | 1 |
| Clineschmidt, BV; McGuffin, JC; Pflueger, AB; Totaro, JA | 1 |
| Kjellberg, B; Randrup, A | 1 |
| Kelder, D; Ross, SB | 1 |
| Goldberg, ME; Salama, AI | 1 |
| Biggio, G; Meek, JL; Moja, E; Neckers, LM | 1 |
| Aghamanian, GK; Davis, M; Gallager, DW | 1 |
| Buckley, JP; Jandhyala, BS; Manian, AA; Perel, JM; Steenberg, ML | 1 |
| Benkert, O; Laakmann, G; Schumacher, G | 1 |
| Kafoe, WF; Leonard, BE | 1 |
| Aghajanian, GK; Wang, RY | 1 |
| Campbell, IC | 1 |
| Shaw, DM | 1 |
| Andrée, G; Meiser, H; Schmitt, W | 1 |
| Detaevernier, MR; Dryon, L; Massart, DL | 1 |
| Klimek, V; Maj, J; Rawlów, A; Sarnek, J | 1 |
| Bossa, R; Dubini, F; Galatulas, I; Tofanetti, O | 1 |
| Hewland, R; Johnson, AL; Macsweeney, DA; Shaw, DM | 1 |
| Krupp, P; Wesp, M | 1 |
| Oksenkrug, GF | 1 |
| Kunihara, M; Nakano, M; Ohyama, M | 1 |
| Kriete, M; Rapoport, JL; Ryland, DH | 1 |
| Leonard, HL; Swedo, SE | 1 |
| Fine, S; Kruesi, MJ; Phillips, RA; Rapoport, JL; Valladares, L | 1 |
| Gordon, CT; Hamburger, SD; Mannheim, GB; Rapoport, JL; State, RC | 1 |
| Molina, VA; Murua, VS | 2 |
| Balant, LP; Balant-Gorgia, AE; Gay, M; Gex-Fabry, M | 1 |
| Cheslow, DL; Hamburger, SD; Lenane, MC; Leonard, HL; Rapoport, JL; Rettew, DC; Swedo, SE | 1 |
| Lenane, MC; Leonard, HL; Rapoport, JL; Rettew, DC; Swedo, SE | 1 |
| Chilco, PJ; Donnan, GA; Kaczmarczyk, SJ; Kalnins, RM; Mendelsohn, FA; Paxinos, G; Woodhouse, DG | 1 |
| Hegenscheid, B; Presber, HW | 1 |
| Insel, TR; Winslow, JT | 1 |
| Beck-Nielsen, H; Brøsen, K; Gram, LF; Grodum, E; Sindrup, SH; Skjold, T | 1 |
| Chatelain, F; Martin, P; Massol, J; Puech, AJ | 1 |
| Basso, AM; Córdoba, NE; Molina, VA; Orsingher, OA | 1 |
| Anderson, K; Fava, M; Rosenbaum, JF | 1 |
| Martin, P; Puech, AJ; Soubrié, P | 1 |
| Rapoport, JL | 2 |
| Lavoie, PA; Tiberi, M | 1 |
| Fasmer, OB; Hole, K; Hunskaar, S | 1 |
| Belon, JP; Martin, P; Massol, J; Puech, AJ; Soubrié, P | 1 |
| Albrecht, V; Alda, M; David, I; Dvoráková, J; Filip, V; Kristofiková, Z; Olájos, S; Sztaniszláv, D; Topinka, J | 1 |
| Cheslow, DL; Hamburger, SD; Koby, EV; Lenane, MC; Leonard, HL; Rapoport, JL; Swedo, SE | 1 |
| Danti, S; Fermanian, J; Frances, H | 1 |
| Cheslow, DL; Goldberger, EL; Lenane, MC; Leonard, HL; Rapoport, JL; Swedo, SE | 1 |
| Goldstein, FJ; Kellstein, DE; Malseed, RT; Ossipov, MH | 1 |
| Ohi, K; Shimoda, K; Takahashi, K; Takahashi, S; Tsujimoto, T; Yamada, N | 1 |
| Chatelain, F; Martin, P; Massol, J; Puech, AJ; Soubrié, P | 1 |
| Martin, P; Simon, P; Soubrie, P | 1 |
| Anderson, R; Mitchell, R | 1 |
| Fehm, HL; Holl, WR; Steiner, K; Teller, W; Voigt, KH | 1 |
| Insel, TR; Zohar, J | 1 |
| Dubois, JP; Pommier, F; Sioufi, A | 1 |
| Cheslow, D; Coffey, M; Leonard, H; Rapoport, JL; Swedo, S | 1 |
| Baumann, P; Cuendet, C; Eap, CB | 1 |
| Brown, GM; Seggie, J | 1 |
| Biegon, A; Gross-Isseroff, R; Israeli, M | 1 |
| Belon, JP; Gaudel, G; Martin, P; Massol, J; Soubrié, P | 1 |
| Broitman, ST; Fóscolo, MR; Rodríguez Echandía, EL | 1 |
| Bonnet, JJ; Chagraoui, A; Costentin, J; Protais, P | 1 |
| Severson, JA; Wilcox, RE; Woodward, JJ | 1 |
| Ageel, AM | 1 |
| el Mestikawy, S; Hamon, M; Martin, P; Simon, P; Soubrie, P; Thiebot, MH | 1 |
| Della Corte, L; Giovannini, MG; Ninci, R; Sgaragli, G | 1 |
| Fischer, W; Heydenreich, F; Rabending, G; Streubel, FR | 1 |
| Chuang, DM; Costa, E; Nakaki, T; Roth, BL | 1 |
| Cohen, O; Globus, M; Melamed, E; Rosenthal, J; Uzzan, A | 1 |
| Brambilla, F; Gambini, O; Maggioni, M; Nobile, P; Pugnetti, L; Scarone, S | 1 |
| Aguirre, M; Broughton, R; Stuss, D | 1 |
| Gillin, JC; Insel, TR; Mueller, EA; Murphy, DL; Siever, LJ | 1 |
| Peterson, SL; St Mary, JS; Trzeciakowski, JP | 1 |
| Lippman, W; Pugsley, TA | 1 |
| Bareggi, SR; Bonaccorsi, A; Franco, R; Garattini, S; Morselli, PL; Mundo, AS; Riva, E | 1 |
| Baker, JC; Fuller, RW; Molloy, BB; Perry, KW | 1 |
| Gugath, M; Laakmann, G; Mueller, OA; Stalla, GK; Treusch, J; Wahlster, U; Wittmann, M | 1 |
| Goldstein, FJ; Kellstein, DE; Malseed, RT | 1 |
| Brown, WA; Haier, RJ; Qualls, CB | 2 |
| Bonanno, G; Marchi, M; Maura, G; Raiteri, M | 1 |
| Jones, RS; Olpe, HR | 1 |
| Fyer, A; Klein, DF; Liebowitz, M; McGrath, P; Quitkin, F; Rifkin, A; Rosnick, L; Stewart, JW | 1 |
| Crews, FT; Smith, CB | 1 |
| Scuvée-Moreau, JJ; Svensson, TH | 1 |
| Cesková, E; Náhunek, K; Rysánek, R; Svestka, J | 1 |
| Gugath, M; Kuss, HJ; Laakmann, G; Zygan, K | 1 |
| Phillis, JW | 1 |
| Buchweitz, E; Roffman, M; Weiss, HR | 1 |
| Kobayashi, A; Nakazawa, K; Sugita, S | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Nakanishi, H; Shibata, S; Ueki, S; Watanabe, S | 1 |
| Carter, RB; Leander, JD | 1 |
| Gabriel, NN; Soliman, KF | 1 |
| Ashkenazi, R; Finberg, JP; Youdim, MB | 1 |
| Schnieden, H; Stein, DM | 1 |
| Olpe, HR; Schellenberg, A | 1 |
| Vinet, B | 1 |
| Briley, MS; Langer, SZ; Sette, M | 1 |
| Devoize, JL; Eschalier, A; Pechadre, JC; Rigal, F | 1 |
| Garfinkel, BD; O'Neill, I; Sloman, L; Wender, PH | 1 |
| Cesková, E; Náhunek, K; Svestka, J | 1 |
| Dupont, A; Merand, Y; Savard, P | 1 |
| Bräunlich, H; Fleck, C | 1 |
| Brown, WA; Qualls, CB | 1 |
| Glusman, S; Haber, B; Ritchie, T | 1 |
| Katz, IR | 1 |
| Amoroso, S; Annunziato, L; Di Renzo, GF; Quattrone, A; Schettini, G | 1 |
| Ziebarth, D | 1 |
| Avdulov, NA; Maĭsov, NI | 1 |
| Laakmann, G | 1 |
| Avdulov, NA; Dobretsov, GE; Val'dman, AV | 1 |
| Bazán, E; Fuentes, JA; Galindo, A; Guillamón, A; Somoza, E; Valencia, A | 1 |
| McGuire, PS; Seiden, LS | 1 |
| Allison, K; Greenshaw, AJ; Ivanová, S | 1 |
| Baker, GB; McManus, DJ; Todd, KG | 1 |
| Cotelingam, M; Gordon, CT; Ludlow, CL; Rapoport, JL; Stager, SV | 1 |
| Blackburn, TP; de Biasi, V; Kennett, GA; Lightowler, S; Stevens, NC; Tulloch, IF; Wood, MD | 1 |
| Cotelingam, GM; Gordon, CT; Hamburger, SD; Ludlow, CL; Rapoport, JL; Stager, S | 1 |
| Joyce, PR; Sullivan, PF | 1 |
| Corbett, R; Cornfeldt, M; Dunn, RW; Smith, C; Szewczak, M; Woods, A | 1 |
| Joyce, PR; Mulder, RT | 1 |
| Asakura, W; Matsumoto, K; Ohta, H; Watanabe, H | 1 |
| Arimoto, H; Fujii, T; Kurihara, Y; Mitsutsuka, Y | 1 |
| Coutts, RT | 1 |
| Cloninger, CR; Joyce, PR; Mulder, RT | 1 |
| Kuroda, Y; Mikuni, M; Ogawa, T; Takahashi, K | 1 |
| Fujita, K; Iijima, N; Nakazawa, K; Suzuki, S | 1 |
| Allison, K; Baker, GB; Greenshaw, AJ; Paetsch, PR | 1 |
| Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N | 1 |
| Lenane, MC; Leonard, HL; Rapoport, JL; Swedo, SE | 1 |
| Goodman, WK; McDougle, CJ; Price, LH | 1 |
| Bellmann, R; Sperk, G | 1 |
| Cohen, LS; Dimmock, JA; Rosenbaum, JF; Sichel, DA | 1 |
| Gordon, CT; Hamburger, SD; Nelson, JE; Rapoport, JL; State, RC | 1 |
| Nomura, S; Sawa, Y; Sekiya, Y; Sugita, R; Terada, K | 1 |
| Allen, AJ; Hamburger, SD; Leonard, HL; Meyer, MC; Rapoport, JL; Richter, D; Swedo, SE; Tucker, E | 1 |
| Oesterheld, J | 1 |
| Joyce, PR; Mulder, RT; Rowe, JB; Sullivan, PF | 1 |
| Erjavec, F; Ferjan, I | 1 |
| Buxeraud, J; Comby, F; Raby, C; Rousseau, A | 1 |
| Joyce, PR; Mulder, RT; Oakley-Browne, MA; Sullivan, PF | 1 |
| Ichikawa, H; Mitsushio, H; Shirayama, Y; Takahashi, K; Takashima, M | 1 |
| Bouwer, C; Niehaus, DJ; Stein, DJ | 1 |
| Anand, A; Barr, LC; Goodman, WK; McDougle, CJ; Price, LH | 1 |
| Frank, MG; Heller, HC | 1 |
| Eschalier, A; Hernández, A; Mestre, C; Pelissier, T | 1 |
| Betz, H; Schloss, P; Sur, C | 1 |
| Ballesta, J; de la Torre, R; González, S; Ortuño, J; Pascual, JA | 1 |
| Chen, JX; Gershon, MD; Pan, H; Rothman, TP; Wade, PR | 1 |
| Misawa, M; Mori, T; Onodera, K; Suzuki, T; Tsuji, M | 1 |
| Bizot, JC | 1 |
| Armario, A; Gómez, F; Graugés, P; Martín, M | 1 |
| Graham, BG; Sattely-Miller, EA; Schiffman, SS; Suggs, MS | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Roos, P | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Pinto, D | 1 |
| Dannon, PN; Fux, M; Iancu, I; Sasson, Y; Taub, M; Zohar, J | 1 |
| Allen, A; Aronowitz, B; Hollander, E; Kwon, J; Schmeidler, J; Simeon, D; Wong, C | 1 |
| Phillips, KA; Price, LH; Rasmussen, SA | 1 |
| Molina-Hernandez, M; Téllez-Alcántara, P | 1 |
| Nath, C; Srivastava, SK | 1 |
| Manev, H; Manev, R; Smalheiser, NR; Uz, T | 1 |
| Guralnik, O; Schmeidler, J; Simeon, D | 1 |
| Balu, R; Davidson, C; Ellinwood, EH; Lee, TH | 1 |
| Ferris, CF; Koppel, G; Messenger, T; Rasmussen, MF | 1 |
| Fernandez-Belda, F; Fortea, I; Plenge-Tellechea, F; Soler, F | 1 |
| Contreras, CM; Molina, M; Tellez-Alcantara, P | 1 |
| Joyce, PR; Mulder, RT; Porter, RJ | 1 |
| Fernández-Guasti, A; Nicolini, H; Ulloa, RE | 1 |
| Nagaraja, MR; Sharada, S; Subhash, MN; Vinod, KY | 1 |
| Fernández-Guasti, A; Martínez-Mota, L | 1 |
| Burgos, H; Campos, M; Castillo, A; Fernández, V; Hernández, A; Mardones, L | 1 |
| de Lima, TC; de Oliveira, RM; del Bel, EA; Guimarães, FS; Lino-de-Oliveira, C; Pádua Carobrez, A | 1 |
| Abdel-Razaq, W; Bates, TE; Kendall, DA | 2 |
| Alves, C; Fernandes, C; Lanças, FM; Rodrigues, JC; Santos-Neto, AJ | 1 |
| Cruz, SL; López-Rubalcava, C; Páez-Martinez, N; Soberanes-Chávez, P | 1 |
| Ipser, JC; Sander, C; Stein, DJ | 1 |
| Corda, MG; Giorgi, O; Piras, G | 1 |
| Bult-Ito, A; Burrow, T; Castillo, MR; Foltz, H; Greene-Schloesser, DM; Gregg, KA; Sheppard, DK; Slater, M; Van der Zee, EA | 1 |
| Dulawa, SC; Masten, VL; Shanahan, NA; Velez, LP | 1 |
| Azar, N; Bassit, M; Cadougan, M; Korobkova, EA; Nemeth, J; Venkatratnam, A | 1 |
| Abdel-Zaher, AO; Farghaly, HS; Kotb, HI; Mostafa, MG | 1 |
| Corda, MG; Giorgi, O; Piludu, MA; Piras, G | 1 |
| Barak, Y; Baratz-Goldstein, R; Hostovsky, A; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I | 1 |
| Derry, S; Hearn, L; Moore, RA; Phillips, T; Wiffen, PJ | 1 |
| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
| Boomhower, SR; Newland, MC | 1 |
| Barbui, C; Bighelli, I; Caldwell, DM; Cipriani, A; Davies, SJ; Dawson, S; Dias, S; Furukawa, TA; Guaiana, G; Imai, H; Koesters, M; Meader, N; Pompoli, A; Robertson, L; Tajika, A | 1 |
9 review(s) available for desipramine and clomipramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[The "obsessive-compulsive spectrum": a useful concept?].
Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Desipramine; Female; Humans; Male; Neurocognitive Disorders; Obsessive-Compulsive Disorder; Tourette Syndrome | 1994 |
Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping.
Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug Interactions; Female; Humans; Hydroxylation; Imipramine; Isoenzymes; Male; Mephenytoin; Nortriptyline; Phenotype; Polymorphism, Genetic | 1994 |
Obsessive compulsive disorder in children and adolescents: issues in management.
Topics: Adolescent; Age Factors; Behavior Therapy; Child; Child, Preschool; Clomipramine; Comorbidity; Counseling; Desipramine; Family Therapy; Female; Humans; Male; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Tic Disorders | 1993 |
The pharmacotherapy of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Buspirone; Clomipramine; Desipramine; Fluoxetine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Sertraline | 1993 |
Pharmacotherapy and psychotherapy for body dysmorphic disorder.
Topics: Adrenergic Uptake Inhibitors; Body Image; Clomipramine; Cognitive Behavioral Therapy; Desipramine; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Somatoform Disorders | 2009 |
Desipramine for neuropathic pain in adults.
Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Pain; Clomipramine; Desipramine; Diabetic Neuropathies; Fluoxetine; Humans; Middle Aged; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2014 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
Pharmacological treatments in panic disorder in adults: a network meta-analysis.
Topics: Adult; Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Clomipramine; Clonazepam; Desipramine; Diazepam; Fluoxetine; Humans; Network Meta-Analysis; Panic Disorder; Paroxetine; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Venlafaxine Hydrochloride | 2023 |
37 trial(s) available for desipramine and clomipramine
| Article | Year |
|---|---|
A comparative trial of Anafranil, Pertofran and an Anafranil/Pertofran combination.
Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depression; Desipramine; Dibenzazepines; Drug Therapy, Combination; Humans; Middle Aged | 1977 |
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Clomipramine; Depression; Desipramine; Dibenzazepines; Double-Blind Method; Drug Interactions; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mianserin; Propranolol | 1978 |
Trial of chlorimipramine and desipramine for Gilles de la Tourette syndrome.
Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Desipramine; Dibenzazepines; Double-Blind Method; Female; Humans; Male; Tourette Syndrome | 1979 |
Clinical pharmacological studies of tandamine, a potential antidepressive drug.
Topics: Adult; Antidepressive Agents, Tricyclic; Appetite; Arousal; Blood Platelets; Blood Pressure; Clomipramine; Desipramine; Dopamine; Female; Humans; Indoles; Male; Middle Aged; Parasympathetic Nervous System; Pupil; Saliva; Serotonin; Tyramine | 1977 |
Tricyclic antidepressants and tryptophan in unipolar depression.
Topics: Clomipramine; Depression; Desipramine; Dibenzazepines; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Placebos; Receptors, Adrenergic; Serotonin; Tryptophan | 1975 |
Drug treatment of canine acral lick. An animal model of obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Animals; Clomipramine; Dermatitis; Desipramine; Disease Models, Animal; Dog Diseases; Dogs; Double-Blind Method; Fenfluramine; Fluoxetine; Follow-Up Studies; Grooming; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Serotonin; Sertraline; Ulcer | 1992 |
Trichotillomania. An obsessive compulsive spectrum disorder?
Topics: Adolescent; Adult; Child; Child, Preschool; Clomipramine; Combined Modality Therapy; Desipramine; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant; Longitudinal Studies; Male; Middle Aged; Obsessive-Compulsive Disorder; Personality Inventory; Psychiatric Status Rating Scales; Trichotillomania | 1992 |
Paraphilias: a double-blind crossover comparison of clomipramine versus desipramine.
Topics: Adult; Clomipramine; Desipramine; Double-Blind Method; Humans; Male; Middle Aged; Paraphilic Disorders; Treatment Outcome | 1992 |
Differential response of seven subjects with autistic disorder to clomipramine and desipramine.
Topics: Adolescent; Anger; Autistic Disorder; Child; Clomipramine; Compulsive Behavior; Desipramine; Double-Blind Method; Female; Humans; Male; Placebos; Psychiatric Status Rating Scales; Single-Blind Method; Stereotyped Behavior | 1992 |
A double-blind desipramine substitution during long-term clomipramine treatment in children and adolescents with obsessive-compulsive disorder.
Topics: Adolescent; Age Factors; Child; Clomipramine; Desipramine; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Recurrence | 1991 |
A double-blind comparison of clomipramine and desipramine treatment of severe onychophagia (nail biting).
Topics: Adult; Ambulatory Care; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Mental Disorders; Nail Biting; Obsessive-Compulsive Disorder; Patient Dropouts; Psychiatric Status Rating Scales; Severity of Illness Index; Trichotillomania | 1991 |
Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study.
Topics: Adult; Aged; Clomipramine; Desipramine; Diabetic Neuropathies; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Phenotype; Sparteine | 1990 |
Neuroendocrine response to clomipramine and desipramine--the evidence of partial determination by heredity and sex.
Topics: Adult; Clomipramine; Desipramine; Female; Genetics; Growth Hormone; Humans; Hydrocortisone; Male; Neurosecretory Systems; Prolactin; Random Allocation; Sex Factors; Single-Blind Method | 1989 |
Treatment of obsessive-compulsive disorder with clomipramine and desipramine in children and adolescents. A double-blind crossover comparison.
Topics: Adolescent; Adult; Age Factors; Child; Clinical Trials as Topic; Clomipramine; Desipramine; Double-Blind Method; Female; Humans; Male; Obsessive-Compulsive Disorder; Placebos; Psychiatric Status Rating Scales; Recurrence | 1989 |
A double-blind comparison of clomipramine and desipramine in the treatment of trichotillomania (hair pulling)
Topics: Adolescent; Adult; Clomipramine; Desipramine; Double-Blind Method; Female; Humans; Obsessive-Compulsive Disorder; Trichotillomania | 1989 |
Acute effects of desipramine and clomipramine on pituitary-adrenal axis in man.
Topics: Adrenocorticotropic Hormone; Adult; Blood Glucose; Clomipramine; Desipramine; Glucose Tolerance Test; Humans; Hydrocortisone; Male; Pituitary-Adrenal System; Time Factors | 1986 |
Obsessive-compulsive disorder: psychobiological approaches to diagnosis, treatment, and pathophysiology.
Topics: Adult; Brain; Clomipramine; Depressive Disorder; Desipramine; Diagnosis, Differential; Female; Humans; Male; Metergoline; Middle Aged; Obsessive-Compulsive Disorder; Piperazines; Serotonin; Synaptic Transmission | 1987 |
Treatment of childhood obsessive compulsive disorder with clomipramine and desmethylimipramine: a double-blind crossover comparison.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Clomipramine; Desipramine; Double-Blind Method; Female; Humans; Male; Obsessive-Compulsive Disorder; Random Allocation | 1988 |
[Quantitative EEG analysis of a single dose of psychotropic drugs in healthy probands].
Topics: Adult; Arousal; Brain; Carbamazepine; Clomipramine; Desipramine; Diazepam; Electroencephalography; Evoked Potentials; Female; Haloperidol; Humans; Imipramine; Male; Psychotropic Drugs | 1986 |
Effects of psychotropic drugs (desimipramine, chlorimipramine, sulpiride and diazepam) on the human HPA axis.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Clomipramine; Desipramine; Diazepam; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Psychotropic Drugs; Sulpiride | 1984 |
Efficacy of desipramine in endogenomorphically depressed patients.
Topics: Adjustment Disorders; Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Norepinephrine; Random Allocation; Serotonin | 1980 |
[Clinical experience with clomipramine (Hydiphen) and desipramine (Petytyl) by parenteral administration in the treatment of endogenous depression with signs of pharmacoresistance].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Desipramine; Drug Resistance; Female; Humans; Infusions, Parenteral; Male; Middle Aged | 1983 |
Comparison of growth hormone and prolactin stimulation induced by chlorimipramine and desimipramine in man in connection with chlorimipramine metabolism.
Topics: Adolescent; Adult; Blood Pressure; Clomipramine; Desipramine; Growth Hormone; Heart Rate; Humans; Male; Prolactin | 1984 |
Fluency changes in persons who stutter following a double blind trial of clomipramine and desipramine.
Topics: Adolescent; Adult; Clomipramine; Cross-Over Studies; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Norepinephrine; Placebos; Serotonin; Severity of Illness Index; Single-Blind Method; Stuttering; Treatment Outcome; Verbal Behavior | 1995 |
A double-blind comparison of clomipramine and desipramine in the treatment of developmental stuttering.
Topics: Adolescent; Adult; Attitude to Health; Clomipramine; Cross-Over Studies; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Personality Inventory; Placebos; Severity of Illness Index; Single-Blind Method; Stuttering; Treatment Outcome | 1995 |
Effects of exclusion criteria in depression treatment studies.
Topics: Adult; Clomipramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Psychiatric Status Rating Scales; Selection Bias; Treatment Outcome | 1994 |
Relationships of the Tridimensional Personality Questionnaire to mood and personality measures for depressed patients.
Topics: Adolescent; Adult; Affect; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female; Humans; Impulsive Behavior; Male; Middle Aged; Personality Inventory; Psychometrics; Reproducibility of Results; Temperament | 1994 |
Temperament predicts clomipramine and desipramine response in major depression.
Topics: Adult; Clomipramine; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Personality Assessment; Prognosis; Temperament; Treatment Outcome | 1994 |
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hospitalization; Humans; Imipramine; Male; Middle Aged; Personality Inventory; Sex Factors; Weight Gain; Weight Loss | 1993 |
A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder.
Topics: Adolescent; Adult; Ambulatory Care; Autistic Disorder; Child; Clomipramine; Desipramine; Double-Blind Method; Female; Humans; Male; Obsessive-Compulsive Disorder; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Stereotyped Behavior; Treatment Outcome | 1993 |
Electrocardiographic changes during desipramine and clomipramine treatment in children and adolescents.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Clomipramine; Cross-Over Studies; Death, Sudden; Depressive Disorder; Desipramine; Double-Blind Method; Electrocardiography; Female; Humans; Male; Placebos; Tachycardia | 1995 |
The effect of a history of conduct disorder in adult major depression.
Topics: Adolescent; Adult; Alcoholism; Antidepressive Agents, Tricyclic; Child; Child Behavior Disorders; Clomipramine; Comorbidity; Depressive Disorder; Desipramine; Diagnosis, Dual (Psychiatry); Double-Blind Method; Female; Humans; Male; Personality Development; Personality Disorders; Psychiatric Status Rating Scales; Risk Factors; Substance-Related Disorders; Treatment Outcome | 1996 |
Intimate bonds in depression.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Interpersonal Relations; Male; Middle Aged; Object Attachment; Personality Inventory; Prognosis; Psychometrics; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1996 |
Addition of desipramine to serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder.
Topics: 1-Naphthylamine; Adrenergic Uptake Inhibitors; Adult; Clomipramine; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Humans; Male; Obsessive-Compulsive Disorder; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome | 1997 |
A double-blind crossover comparison of clomipramine and desipramine in the treatment of panic disorder.
Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Cross-Over Studies; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Time Factors | 1999 |
Clomipramine vs desipramine crossover trial in body dysmorphic disorder: selective efficacy of a serotonin reuptake inhibitor in imagined ugliness.
Topics: Adrenergic Uptake Inhibitors; Adult; Clomipramine; Comorbidity; Cross-Over Studies; Delusions; Desipramine; Double-Blind Method; Female; Humans; Male; Mental Disorders; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Somatoform Disorders; Treatment Outcome | 1999 |
Baseline prolactin and L-tryptophan availability predict response to antidepressant treatment in major depression.
Topics: Administration, Oral; Adolescent; Adult; Antidepressive Agents, Tricyclic; Biological Availability; Clomipramine; Depressive Disorder, Major; Desipramine; Double-Blind Method; Female; Fenfluramine; Humans; Hydrocortisone; Male; Menstrual Cycle; Middle Aged; Prolactin; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan | 2003 |
203 other study(ies) available for desipramine and clomipramine
| Article | Year |
|---|---|
Antidepressant agents. 9. 3,3-Diphenylcyclobutylamines, a new class of central stimulants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Behavior, Animal; Brain; Butylamines; Central Nervous System Stimulants; Cyclization; Dopamine; Drug Interactions; In Vitro Techniques; Male; Mice; Motor Activity; Norepinephrine; Pupil; Serotonin | 1978 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry; Dopamine; Isoquinolines; Male; Molecular Conformation; Motor Activity; Norepinephrine; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Synaptosomes; Tetrabenazine | 1987 |
1-Aryl-2-(aminomethyl)cyclopropanecarboxylic acid derivatives. A new series of potential antidepressants.
Topics: Amino Acids; Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Cyclopropanes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Spectrophotometry, Infrared; Structure-Activity Relationship; Yohimbine | 1987 |
Synthesis and anxiolytic activity of a series of pyrazino[1,2-a][1,4]benzodiazepine derivatives.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Apomorphine; Benzodiazepines; Diazepam; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Male; Norepinephrine; Pyrazines; Rats; Receptors, Drug; Serotonin | 1980 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Synthesis of pyridylallylamines related to zimelidine and their inhibition of neuronal monoamine uptake.
Topics: Animals; Biogenic Amines; Brain; Brompheniramine; Chemical Phenomena; Chemistry; In Vitro Techniques; Male; Mice; Molecular Conformation; Neurons; Norepinephrine; Pyridines; Serotonin; Structure-Activity Relationship; Zimeldine | 1981 |
Novel tetracyclic spiropiperidines. 1. 3-Aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidines] as potential antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Chemical Phenomena; Chemistry; Drug Synergism; Male; Mice; Physostigmine; Piperidines; Spiro Compounds; Tetrabenazine | 1981 |
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Lactams; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Pyrrolidinones; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Blood and brain concentrations of imipramine, clomipramine and their monomethylated metabolites after oral and intramuscular administration in rats.
Topics: Administration, Oral; Animals; Clomipramine; Desipramine; Dibenzazepines; Imipramine; Injections, Intramuscular; Male; Rats; Time Factors | 1977 |
Tricyclic antidepressant drugs as antagonists of muscarinic receptors in sympathetic ganglia.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Antidepressive Agents, Tricyclic; Cats; Clomipramine; Desipramine; Dimethylphenylpiperazinium Iodide; Ganglia, Autonomic; Ganglia, Spinal; Imipramine; Iprindole; Nictitating Membrane; Norepinephrine; Receptors, Cholinergic; Receptors, Muscarinic; Serotonin; Viloxazine | 1976 |
The effect of tricyclic antidepressants on corticofugal inhibition of the spinal trigeminal nucleus.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brompheniramine; Cats; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Drug Combinations; Imipramine; Neural Inhibition; Procyclidine; Spinal Cord; Trigeminal Nerve | 1977 |
Inhibition of 5-HT uptake into neurons and platelets in mice treated chronically with chlorimipramine and femoxetine.
Topics: Animals; Anisoles; Blood Platelets; Clomipramine; Desipramine; Female; Mice; Neurons; Nialamide; Piperidines; Serotonin; Serotonin Antagonists; Time Factors | 1979 |
Effect of etoperidone on the depletion of brain 5-hydroxytryptamine and catecholamines induced respectively by p-chloromethamphetamine and 6-hydroxydopamine in rats.
Topics: Animals; Antidepressive Agents; Brain; Catecholamines; Clomipramine; Desipramine; Dopamine; Hydroxydopamines; Male; Methamphetamine; Norepinephrine; Piperazines; Rats; Serotonin; Time Factors; Trazodone | 1979 |
Physiological and pharmacological evidence for a serotonergic projection to the hippocampus.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Bicuculline; Clomipramine; Cyproheptadine; Desipramine; Fenclonine; Hippocampus; Hydroxyindoleacetic Acid; Iontophoresis; Lysergic Acid Diethylamide; Male; Methysergide; Neural Pathways; Rats; Reaction Time; Reticular Formation; Serotonin; Synaptic Transmission | 1975 |
Determination of chloroimipramine and its demethyl metabolite in plasma by ion-pair partition chromatography.
Topics: Alkanes; Butanols; Chromatography, Ion Exchange; Clomipramine; Desipramine; Dibenzazepines; Humans; Imipramine; Mesylates; Methyl Chloride | 1976 |
Release of endogenous serotonin from two identified serotonin-containing neurones and the physiological role of serotonin re-uptake.
Topics: Action Potentials; Animals; Aplysia; Clomipramine; Desipramine; In Vitro Techniques; Membrane Potentials; Neurons; Potassium; Secretory Rate; Serotonin; Synaptic Transmission | 1978 |
Enhancement of central norepinephrine and 5-hydroxytryptamine transmission by tricyclic antidepressants. A comparison.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cats; Clomipramine; Desipramine; Electric Stimulation; Female; Imipramine; Male; Norepinephrine; Serotonin; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission; Time Factors | 1979 |
Substituted amphetamine derivatives. II. Behavioural effects in mice related to monoaminergic neurones.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Behavior, Animal; Brain; Clomipramine; Desipramine; Dopamine; Drug Synergism; Levodopa; Male; Mice; Motor Activity; Neurons; Norepinephrine; Reserpine; Serotonin | 1977 |
Blockade of para-methoxyamphetamine induced serotonin release by serotonin uptake inhibitors.
Topics: Amphetamines; Animals; Brain; Clomipramine; Desipramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Muscle Contraction; Rats; Serotonin; Serotonin Antagonists | 1978 |
Effects of drugs on hyperactivity and aggression induced by raphe lesions in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Atropine; Brain Stem; Clomipramine; Desipramine; Humans; Imipramine; Male; Methyltyrosines; Motor Activity; Raphe Nuclei; Rats | 1978 |
Hydroxytryptamine uptake inhibitors block para- methoxyamphetamine-induced 5-HT release.
Topics: Amphetamines; Animals; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Male; Methysergide; Muscle Contraction; Pargyline; Rats; Serotonin | 1979 |
Effects of clomipramine and other inhibitors of monoamine uptake on the sexual behaviour of female rats and rhesus monkeys.
Topics: Animals; Clomipramine; Desipramine; Dibenzazepines; Estrogens; Female; Haplorhini; Macaca mulatta; Norepinephrine; Progesterone; Protriptyline; Rats; Serotonin; Sexual Behavior, Animal | 1977 |
Metabolism of 5-hydroxytryptamine and levels of tricyclic antidepressant drugs in rat brain after acute and chronic treatment.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Desipramine; Drug Administration Schedule; Imipramine; Male; Probenecid; Protriptyline; Rats; Serotonin | 1977 |
High-affinity 3H-imipramine binding in rat cerebral cortex.
Topics: Amitriptyline; Animals; Binding Sites; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; In Vitro Techniques; Male; Rats | 1979 |
A sensitive method for the simultaneous determination in biological fluids of imipramine and desipramine or clomipramine and N-desmethylclomipramine by gas chromatography mass spectrometry.
Topics: Chromatography, Gas; Clomipramine; Dealkylation; Desipramine; Humans; Imipramine; Mass Spectrometry; Methods | 1979 |
Hydroxylated metabolites of tricyclic antidepressants: preclinical assessment of activity.
Topics: Animals; Antidepressive Agents, Tricyclic; Biotransformation; Cerebral Cortex; Clomipramine; Desipramine; Hydroxylation; Imipramine; Male; Motor Activity; Norepinephrine; Rats; Reserpine; Serotonin; Synaptosomes; Tissue Distribution | 1979 |
Effects of somatic treatments on mood in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clomipramine; Depression; Desipramine; Electroconvulsive Therapy; Emotions; Evaluation Studies as Topic; Female; Humans; Male; Maprotiline; Middle Aged; Psychological Tests; Time Factors | 1979 |
Tricyclic antidepressant drugs: antagonism of effect of D-lysergic acid diethylamide (LSD) on shock elicited aggression.
Topics: Aggression; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Electroshock; Humans; Lysergic Acid Diethylamide; Male; Rats | 1977 |
Substituted amphetamine derivatives. I. Effect on uptake and release of biogenic monoamines and on monoamine oxidase in the mouse brain.
Topics: Amphetamines; Animals; Biogenic Amines; Brain; Clomipramine; Desipramine; Dopamine; Male; Mice; Monoamine Oxidase; Norepinephrine; Serotonin | 1977 |
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Humans; Imipramine; Maprotiline; Protriptyline | 1979 |
A simple method for the determination of therapeutic levels of clomipramine, imipramine and desipramine.
Topics: Chromatography, Thin Layer; Clomipramine; Desipramine; Dibenzazepines; Humans; Imipramine | 1977 |
The thermal effects of interaction between d-amphetamine and antidepressants among rats kept at various ambient temperatures.
Topics: Animals; Antidepressive Agents; Body Temperature; Clomipramine; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Male; Maprotiline; Rats | 1977 |
Inhibition of the serotoninergic uptake system by MK-212 (6-chloro-2-[1-piperazinyl]-pyrazine)
Topics: Animals; Cerebral Cortex; Clomipramine; Depression, Chemical; Desipramine; Dopamine; Female; In Vitro Techniques; Neurons; Norepinephrine; p-Chloroamphetamine; Piperazines; Pyrazines; Rats; Serotonin | 1978 |
Behavioral effects of thymoleptics in vervet monkeys (Cercopithecus aethiops).
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chlorocebus aethiops; Clomipramine; Desipramine; Female; Haplorhini; Iprindole; Male; Motor Activity; Posture | 1975 |
Efflux of 5-hydroxytryptamine from synaptosomes of rat cerebral cortex.
Topics: Alanine; Allylamine; Amphetamines; Animals; Cerebral Cortex; Chromatography, Thin Layer; Clomipramine; Desipramine; In Vitro Techniques; Male; Ouabain; Pargyline; Pyridines; Rats; Receptors, Serotonin; Reserpine; Serotonin; Serotonin Antagonists; Synaptosomes; Temperature | 1977 |
Neurochemical properties of 3,3-dimethyl-1-[3-(methylamino) propyl]-1-phenylindan HCl (LU 3-049) and selected tricyclic antidepressants.
Topics: Amphetamines; Animals; Antidepressive Agents; Biogenic Amines; Brain Chemistry; Cerebral Cortex; Clomipramine; Desipramine; Indans; Indenes; Male; Monoamine Oxidase; Norepinephrine; Propylamines; Rats; Serotonin | 1977 |
Modulation of brain tryptophan hydroxylase activity by brain tryptophan content.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Clomipramine; Desipramine; Diet; Male; Mixed Function Oxygenases; Phenyl Ethers; Propylamines; Rats; Serotonin; Spinal Cord; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1977 |
Tricyclic antidepressant drugs: attenuation of excitatory effects of d-lysergic acid diethylamide (LSD) on acoustic startle response.
Topics: Acoustic Stimulation; Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Imipramine; Lysergic Acid Diethylamide; Male; Methyltyrosines; Rats; Reflex, Startle; Time Factors | 1977 |
Effects of several tricyclic antidepressants on the hemodynamics and myocardial contractility of the anesthetized dogs.
Topics: Animals; Antidepressive Agents, Tricyclic; Cardiac Output; Clomipramine; Desipramine; Dogs; Heart Rate; Hemodynamics; Imipramine; In Vitro Techniques; Myocardial Contraction; Time Factors | 1977 |
Stimulation of growth hormone secretion by desimipramin and chlorimipramin in man.
Topics: Adult; Clomipramine; Desipramine; Dibenzazepines; Growth Hormone; Humans; Kinetics; Male | 1977 |
Effects of Org 6582, chlorimipramine and desmethylimipramine on the depletion of biogenic amines from the rat brain in vivo.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clomipramine; Desipramine; Dibenzazepines; Dopamine; Drug Interactions; Male; Norepinephrine; Rats; Serotonin; Tyramine | 1977 |
Antidromically identified serotonergic neurons in the rat midbrain raphe: evidence for collateral inhibition.
Topics: Action Potentials; Animals; Clomipramine; Desipramine; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hydroxydopamines; Mesencephalon; Neural Inhibition; Neurons, Afferent; Rats; Serotonin; Tegmentum Mesencephali | 1977 |
Effects of 4-methyl-alpha-ethyl-tyramine, 4, alpha-dimethyl-tyramine and tetrabenazine on the release and uptake of 5-hydroxytryptamine by human blood platelets in vitro.
Topics: Blood Platelets; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; In Vitro Techniques; Serotonin; Temperature; Tetrabenazine; Time Factors; Tyramine | 1976 |
(Z)-dimethylamino-1-(4-bromophenyl)-1-(3-pyridyl) propene (h 102/09), a new selective inhibitor of the neuronal 5-hydroxytryptamine uptake.
Topics: Animals; Brain; Clomipramine; Desipramine; Dopamine; Male; Mice; Norepinephrine; Pyridines; Reserpine; Serotonin; Time Factors | 1976 |
Tricyclic antidepressants, tryptophan and affective disorder.
Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depression; Desipramine; Humans; Serotonin; Tryptophan | 1976 |
[Psychotropic drugs and glaucoma (author's transl)].
Topics: Adult; Aged; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Female; Fluphenazine; Glaucoma; Humans; Imipramine; Intraocular Pressure; Male; Middle Aged; Opipramol; Perazine; Psychotropic Drugs; Thiothixene; Tonometry, Ocular | 1976 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
On the anticataleptic action of cyproheptadine.
Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone | 1976 |
[Antimitotic activity of some derivatives of imipramine].
Topics: Cells, Cultured; Clomipramine; Desipramine; Dibenzazepines; Humans; Imipramine; Lectins; Lymphocytes; Mitosis | 1975 |
Inhibition of prostaglandin synthetase by psychotropic drugs.
Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents; Arachidonic Acids; Cattle; Chlorpromazine; Clomipramine; Desipramine; Enzyme Inhibitors; Haloperidol; Imipramine; Male; Mixed Function Oxygenases; Prostaglandins; Psychotropic Drugs; Seminal Vesicles | 1975 |
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines | 1975 |
Central monoaminergic mechanisms in mice and analgesic activity of spiradoline mesylate, a selective kappa-opioid receptor agonist.
Topics: Analgesics; Animals; Brain; Clomipramine; Desipramine; Fenclonine; Imipramine; Male; Mice; Mice, Inbred ICR; Morphine; Norepinephrine; Phenoxybenzamine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Reserpine; Serotonin | 1992 |
Effects of chronic variable stress and antidepressant drugs on behavioral inactivity during an uncontrollable stress: interaction between both treatments.
Topics: Animals; Antidepressive Agents; Arousal; Clomipramine; Desipramine; Escape Reaction; Helplessness, Learned; Imipramine; Motor Activity; Phenelzine; Rats; Stress, Psychological | 1992 |
Persistent impairment of clomipramine demethylation in recently detoxified alcoholic patients.
Topics: Adult; Alcoholism; Clomipramine; Dealkylation; Desipramine; Female; Humans; Hydroxylation; Imipramine; Male; Middle Aged; Models, Biological | 1992 |
Chronic antidepressant counteracts the conditioned analgesia induced by a context previously associated with inescapable shock.
Topics: Analgesia; Animals; Antidepressive Agents; Clomipramine; Conditioning, Classical; Desipramine; Electroshock; Male; Naloxone; Phenelzine; Rats; Rats, Inbred Strains; Reaction Time | 1991 |
Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography.
Topics: Aged; Benztropine; Binding, Competitive; Biological Transport; Brain Chemistry; Brain Mapping; Caudate Nucleus; Citalopram; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Humans; Locus Coeruleus; Mazindol; Medulla Oblongata; Mianserin; Middle Aged; Norepinephrine; Piperazines; Pons; Substantia Nigra | 1991 |
[Antiprotozoal effects of benzodiazepine derivatives].
Topics: Animals; Benzodiazepines; Chlorpromazine; Clomipramine; Crithidia; Desipramine; Eukaryota; Imipramine; Leishmania mexicana; Metronidazole; Trichomonas vaginalis; Trypanosoma cruzi | 1990 |
Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups.
Topics: Animals; Body Temperature; Catecholamines; Citalopram; Clomipramine; Desipramine; Flumazenil; Mazindol; Motor Activity; Naltrexone; Nortriptyline; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stress, Psychological; Ultrasonics; Vocalization, Animal | 1990 |
Tricyclic antidepressants, thyroid function, and their relationship with the behavioral responses in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arousal; Avoidance Learning; Clomipramine; Conditioning, Classical; Desipramine; Diabetes Mellitus, Experimental; Escape Reaction; Helplessness, Learned; Imipramine; Male; Rats; Rats, Inbred Strains; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1990 |
Gangliosides enhance the anti-immobility response elicited by several antidepressant treatments in mice.
Topics: Animals; Antidepressive Agents; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Electroshock; Gangliosides; Halothane; Male; Mianserin; Mice; Motor Activity; Nialamide | 1990 |
"Anger attacks": possible variants of panic and major depressive disorders.
Topics: Adult; Anger; Anxiety Disorders; Clomipramine; Clonazepam; Depressive Disorder; Desipramine; Diagnosis, Differential; Fear; Female; Humans; Male; Middle Aged; Panic; Retrospective Studies | 1990 |
Reversal of helpless behavior by serotonin uptake blockers in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Clomipramine; Desipramine; Helplessness, Learned; Male; Rats; Rats, Inbred Strains; Reinforcement Schedule; Serotonin Antagonists | 1990 |
Treatment of behavioral disorders in animals.
Topics: Animal Diseases; Animals; Animals, Domestic; Clomipramine; Desipramine; Disease Models, Animal; Dog Diseases; Dogs; Mental Disorders | 1990 |
Inhibition of fast axonal transport in bullfrog nerves by dibenzazepine and dibenzocycloheptadiene calmodulin inhibitors.
Topics: Acetylcholinesterase; Adenosine Triphosphate; Amitriptyline; Animals; Axonal Transport; Calmodulin; Clomipramine; Desipramine; Ganglia, Spinal; Imipramine; In Vitro Techniques; Microtubules; Phosphocreatine; Rana catesbeiana; Spinal Nerves | 1986 |
Antinociceptive effects of serotonergic reuptake inhibitors in mice.
Topics: Alanine; Analgesics; Animals; Citalopram; Clomipramine; Desipramine; Formaldehyde; Hot Temperature; Male; Mice; Neurotransmitter Uptake Inhibitors; Serotonin Antagonists; Substance P | 1989 |
Helpless behavior (escape deficits) in streptozotocin-diabetic rats: resistance to antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brain; Clenbuterol; Clomipramine; Conditioning, Operant; Desipramine; Diabetes Mellitus, Experimental; Electroshock; Escape Reaction; Helplessness, Learned; Imipramine; Insulin; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Triiodothyronine | 1989 |
Effect of tricyclic antidepressant drugs in the isolation-induced social behavioural deficit test.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Reference Values; Social Behavior; Social Isolation | 1989 |
Effect of chronic treatment with tricyclic antidepressants upon antinociception induced by intrathecal injection of morphine and monoamines.
Topics: Analgesia; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Drug Interactions; Fluoxetine; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Time Factors | 1988 |
Chronic administration of tricyclic antidepressants suppresses hypothalamo-pituitary-adrenocortical activity in male rats.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Corticosterone; Desipramine; Dexamethasone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Imipramine; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains | 1988 |
Impaired response of experimental diabetic mice to tricyclics: a possible beta-adrenergic mechanism.
Topics: Animals; Clenbuterol; Clomipramine; Desipramine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypothermia, Induced; Imipramine; Male; Mice; Motor Activity; Receptors, Adrenergic, beta; Thyroxine; Triiodothyronine | 1988 |
Shuttle-box deficits induced by inescapable shocks in rats: reversal by the beta-adrenoreceptor stimulants clenbuterol and salbutamol.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Avoidance Learning; Clenbuterol; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Electroshock; Ethanolamines; Helplessness, Learned; Male; Rats; Rats, Inbred Strains | 1986 |
Effects of GABA receptor agonists on [3H]dopamine release from median eminence and pituitary neurointermediate lobe.
Topics: Animals; Bicuculline; Clomipramine; Desipramine; Dopamine; In Vitro Techniques; Male; Median Eminence; Muscimol; Pituitary Gland; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Simultaneous determination of clomipramine and its N-desmethyl metabolite in human whole blood by capillary gas chromatography with mass-selective detection.
Topics: Clomipramine; Desipramine; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents | 1988 |
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine | 1988 |
Effects of antidepressants on entrainment of circadian rhythms.
Topics: Animals; Body Temperature; Circadian Rhythm; Clomipramine; Corticosterone; Desipramine; Male; Melatonin; Rats; Rats, Inbred Strains | 1988 |
Autoradiographic analysis of [3H]desmethylimipramine binding in the human brain postmortem.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Binding, Competitive; Brain; Clomipramine; Desipramine; Female; Humans; Male; Mianserin; Middle Aged; Pargyline; Postmortem Changes | 1988 |
Thyroid function and reversal by antidepressant drugs of depressive-like behavior (escape deficits) in rats.
Topics: Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Escape Reaction; Hypothyroidism; Imipramine; Male; Nialamide; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Triiodothyronine | 1987 |
Effect of the chronic ingestion of chlorimipramine and desipramine on the hole board response to acute stresses in male rats.
Topics: Animals; Clomipramine; Desipramine; Grooming; Male; Motor Activity; Rats; Restraint, Physical; Stereotyped Behavior; Stress, Psychological | 1987 |
Interactions of amineptine with the neuronal dopamine uptake system: neurochemical in vitro and in vivo studies.
Topics: Animals; Antidepressive Agents, Tricyclic; Cerebellum; Cerebral Cortex; Clomipramine; Corpus Striatum; Desipramine; Dextroamphetamine; Dibenzocycloheptenes; Dopamine; Dopamine Antagonists; In Vitro Techniques; Male; Mice; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Synaptosomes | 1987 |
Subdivision of mouse brain [3H]imipramine binding based on ion dependence and serotonin sensitivity.
Topics: Animals; Binding Sites; Brain; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Kinetics; Mice; Potassium Chloride; Serotonin; Sodium Chloride; Synaptosomes; Tissue Distribution | 1986 |
Effects of desipramine and chlorimipramine on buprenorphine analgesia in mice.
Topics: Analgesics; Animals; Biogenic Amines; Brain; Buprenorphine; Clomipramine; Desipramine; Drug Interactions; Male; Mice; Morphinans; Reaction Time; Spinal Cord | 1986 |
The lesion of serotonergic neurons does not prevent antidepressant-induced reversal of escape failures produced by inescapable shocks in rats.
Topics: Animals; Antidepressive Agents; Clomipramine; Desipramine; Helplessness, Learned; Imipramine; Male; Nialamide; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Isothermal gas chromatographic determination of nanogram amounts of chlorimipramine, chlorpromazine and their N-desmethyl metabolites in plasma using nitrogen-selective detection.
Topics: Chlorpromazine; Chromatography, Gas; Clomipramine; Desipramine; Humans; Indicators and Reagents | 1986 |
5-Hydroxytryptamine uptake and imipramine binding sites in neurotumor NCB-20 cells.
Topics: Animals; Binding Sites; Brain; Clomipramine; Cricetinae; Cricetulus; Desipramine; Fluoxetine; Hybrid Cells; Imipramine; Iprindole; Kinetics; Mianserin; Neuroblastoma; Opipramol; Rats; Serotonin | 1985 |
Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Nomifensine; Norepinephrine; Pyridines; Serotonin Antagonists | 1985 |
Abnormal anterior pituitary responsiveness to hypothalamic hormones in depression: neurophysiological correlates and psychopharmacological effects.
Topics: Adult; Aged; Bipolar Disorder; Clomipramine; Depressive Disorder; Desipramine; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; Male; Middle Aged; Sleep; Thyrotropin-Releasing Hormone | 1985 |
Does memory impairment exist in narcolepsy-cataplexy?
Topics: Adult; Aged; Cataplexy; Clomipramine; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Memory; Mental Recall; Methylphenidate; Middle Aged; Narcolepsy; Neuropsychological Tests; Sleep, REM | 1985 |
Tricyclic response in obsessive compulsive disorder.
Topics: Adolescent; Adult; Clomipramine; Clorgyline; Desipramine; Dexamethasone; Double-Blind Method; Electroencephalography; Female; Growth Hormone; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Sleep | 1985 |
Chronic but not acute treatment with antidepressants enhances the electroconvulsive seizure response in rats.
Topics: Amoxapine; Animals; Antidepressive Agents; Clomipramine; Convulsants; Desipramine; Electric Stimulation; Male; Mianserin; Pargyline; Rats; Rats, Inbred Strains; Seizures | 1985 |
Effect of butriptyline on the brain uptake mechanisms for noradrenaline and 5-hydroxytryptamine.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain Chemistry; Catecholamines; Clomipramine; Desipramine; Dibenzocycloheptenes; Drug Synergism; Hypothalamus; Male; Medulla Oblongata; Mice; Norepinephrine; Phenethylamines; Rats; Serotonin | 1974 |
Relationships between tricyclic antidepressant concentrations, 1-3H-noradrenaline uptake and chronotropic effect in isolated rat atria.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Radioisotopes; Chromatography, Thin Layer; Clomipramine; Dealkylation; Desipramine; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Female; Heart Atria; Heart Rate; Norepinephrine; Nortriptyline; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors; Tritium | 1974 |
6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats.
Topics: Amphetamines; Animals; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Clomipramine; Desipramine; Half-Life; Hydroxyindoleacetic Acid; Male; Mitochondria; Molecular Conformation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Naphthalenes; Rats; Serotonin; Time Factors | 1974 |
Contrasting effects of acute vs. chronic tricyclic antidepressant treatment on central morphine analgesia.
Topics: Analgesia; Animals; Clomipramine; Desipramine; Male; Morphine; Pain; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Serotonin; Time Factors | 1984 |
Dexamethasone suppression test identifies subtypes of depression which respond to different antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Depression, Chemical; Desipramine; Dexamethasone; Diagnosis, Differential; Female; Humans; Imipramine; Male; Pituitary-Adrenal System | 1980 |
Is there a functional linkage between neurotransmitter uptake mechanisms and presynaptic receptors?
Topics: Acetylcholine; Animals; Clomipramine; Clonidine; Cocaine; Desipramine; Dopamine; Hemicholinium 3; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Nomifensine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Synaptosomes | 1984 |
An increase in sensitivity of rat cingulate cortical neurones to substance P occurs following withdrawal of chronic administration of antidepressant drugs.
Topics: Action Potentials; Animals; Antidepressive Agents; Clomipramine; Desipramine; Diazepam; Drug Resistance; Fluphenazine; Gyrus Cinguli; Male; Neurons; Rats; Substance P; Time Factors; Trimipramine; Zimeldine | 1984 |
Potentiation of responses to adrenergic nerve stimulation in isolated rat atria during chronic tricyclic antidepressant administration.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Electric Stimulation; Heart Atria; In Vitro Techniques; Iprindole; Male; Muscles; Nerve Endings; Norepinephrine; Nortriptyline; Rats; Receptors, Adrenergic, alpha; Stimulation, Chemical; Sympathetic Nervous System | 1980 |
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine | 1982 |
Potentiation of the action of adenosine on cerebral cortical neurones by the tricyclic antidepressants.
Topics: Action Potentials; Adenosine; Animals; Antidepressive Agents, Tricyclic; Caffeine; Cerebral Cortex; Clomipramine; Desipramine; Drug Synergism; Iprindole; Male; Neurons; Nortriptyline; Rats; Rats, Inbred Strains | 1984 |
Immediate vs. long-term desmethylimipramine or chlorimipramine: effects on regional cerebral blood flow.
Topics: Animals; Blood Gas Analysis; Cerebrovascular Circulation; Clomipramine; Desipramine; Female; Hemodynamics; Male; Rabbits; Time Factors | 1984 |
High-performance liquid chromatographic determination of imipramine and desipramine in human serum.
Topics: Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Humans; Imipramine | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats.
Topics: Aggression; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorpromazine; Clomipramine; Desipramine; Diazepam; Humans; Injections; Male; Microinjections; Olfactory Bulb; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists | 1984 |
Effect of biogenic amines reuptake inhibition on ethanol induced hypothermia.
Topics: Animals; Biogenic Amines; Clomipramine; Desipramine; Ethanol; Hypothermia; Male; Mice; Mice, Inbred Strains | 1983 |
Effects of LM 5008, a selective inhibitor of 5-hydroxytryptamine uptake, on blood pressure and responses to sympathomimetic amines.
Topics: Angiotensin II; Animals; Blood Pressure; Clomipramine; Desipramine; Drug Interactions; Female; Male; Norepinephrine; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Serotonin Antagonists; Species Specificity; Sympathomimetics; Tyramine | 1983 |
Effect of antidepressant drugs on the in-vitro egg-penetrating ability of golden hamster epididymal spermatozoa.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Cricetinae; Desipramine; Female; Fertilization; Fertilization in Vitro; Male; Maleates; Mesocricetus; Mianserin; Nomifensine; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Viloxazine | 1983 |
The sensitivity of cortical neurons to serotonin: effect of chronic treatment with antidepressants, serotonin-uptake inhibitors and monoamine-oxidase-blocking drugs.
Topics: Animals; Benzofurans; Cerebral Cortex; Clomipramine; Clorgyline; Desipramine; Electric Conductivity; gamma-Aminobutyric Acid; Male; Monoamine Oxidase Inhibitors; Neurons; Piperidines; Rats; Selegiline; Serotonin; Serotonin Antagonists | 1981 |
Column deactivation in analysis for underivatized tricyclic antidepressants by gas chromatography with use of a nitrogen detector.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Humans; Imipramine; Nitrogen; Nortriptyline | 1983 |
Complex inhibition of [3H]imipramine binding by serotonin and nontricyclic serotonin uptake blockers.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1983 |
Activities of five antidepressants in a behavioral pain test in rats.
Topics: Analgesia; Animals; Antidepressive Agents; Clomipramine; Desipramine; Electroshock; Male; Maprotiline; Nociceptors; Nomifensine; Rats; Rats, Inbred Strains; Viloxazine | 1983 |
Tricyclic antidepressant and methylphenidate treatment of attention deficit disorder in children.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Clomipramine; Desipramine; Double-Blind Method; Humans; Male; Methylphenidate; Psychomotor Performance | 1983 |
[Comparison of the onset of the therapeutic effect of clomipramine and desipramine after oral and intravenous administration in patients with endogenous depression].
Topics: Administration, Oral; Clomipramine; Depressive Disorder; Desipramine; Humans; Infusions, Parenteral | 1983 |
3H-mepyramine binding in various regions of rat brain following chronic treatment with different classes of antidepressant drugs.
Topics: Aminopyridines; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Female; Iprindole; Nomifensine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1 | 1982 |
Failure of physostigmine in intoxications with tricyclic antidepressants in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Clomipramine; Desipramine; Drug Interactions; Female; Heart Rate; Imipramine; Lethal Dose 50; Physostigmine; Rats; Rats, Inbred Strains; Respiration; Time Factors | 1982 |
On the kinetics of imipramine and related antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Desipramine; Half-Life; Humans; Imipramine; Kinetics; Rats | 1980 |
Pituitary-adrenal disinhibition in depression: marker of a subtype with characteristic clinical features and response to treatment?
Topics: Adult; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Pituitary-Adrenal System; Recurrence | 1981 |
The filum terminale of the frog spinal cord, a nontransformed glial preparation: II. Uptake of serotonin.
Topics: Animals; Biological Transport; Cauda Equina; Clomipramine; Desipramine; Dihydroxytryptamines; Fluoxetine; Kinetics; Neuroglia; Rana pipiens; Serotonin; Sodium | 1981 |
Monoamine oxidase-catalyzed metabolism of 3,4-dihydroxyphenylethylamine in the dopaminergic synaptosomes from rat corpus striatum.
Topics: Animals; Benztropine; Clomipramine; Clorgyline; Corpus Striatum; Desipramine; Dopamine; Kinetics; Male; Monoamine Oxidase; Pargyline; Rats; Rats, Inbred Strains; Synaptosomes | 1982 |
An in vivo useful tool to evaluate the activity of serotonin uptake inhibitors: prevention by chlorimipramine of the prolactin releasing action of d-fenfluramine.
Topics: Animals; Biological Transport, Active; Brain; Clomipramine; Desipramine; Fenfluramine; Male; Prolactin; Rats; Serotonin | 1982 |
[Comparative studies of the nitrosation behavior of drugs by constant pH value and under simulated stomach conditions].
Topics: Aminopyrine; Ampicillin; Biotransformation; Clomipramine; Desipramine; Dipyrone; Ethambutol; Gastric Acidity Determination; Gastric Mucosa; Humans; Imipramine; Neoplasms; Nitrites; Nitroso Compounds; Oxacillin; Penicillins; Piperazines | 1982 |
[Atypical antidepressants: effect on synaptosomal uptake of serotonin and GABA].
Topics: Animals; Antidepressive Agents; Brain; Carbazoles; Carbolines; Clomipramine; Depression, Chemical; Desipramine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Oxazines; Piperazines; Rats; Serotonin; Synaptosomes; Trazodone | 1981 |
[Effect of antidepressants on the secretion of pituitary hormones in healthy subjects, neurotic depressive patients and endogenous depressive patients (author's transl)].
Topics: Adult; Anthracenes; Clomipramine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Isoquinolines; Luteinizing Hormone; Male; Maprotiline; Middle Aged; Nomifensine; Pituitary Hormones, Anterior; Prolactin; Thyrotropin | 1980 |
The dexamethasone suppression test in the identification subtypes of depression differentially responsive to antidepressants [proceedings].
Topics: Adult; Age Factors; Aged; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Radioimmunoassay; Statistics as Topic | 1981 |
[Correlation between antidepressant membrane affinity and their effects on neuromediator reuptake].
Topics: Affinity Labels; Antidepressive Agents; Carbazoles; Clomipramine; Desipramine; Imipramine; Liposomes; Membrane Lipids; Phospholipids; Piperazines | 1981 |
Antidepressants inhibit enkephalin binding to synaptosome-enriched fractions of rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Synaptosomes; Viloxazine | 1981 |
The effects of tricyclic antidepressants on performance under a differential-reinforcement-of-low-rates schedule in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Imipramine; Male; Rats; Reinforcement Schedule; Scopolamine | 1980 |
Behavioural response to SKF 38393 and quinpirole following chronic antidepressant treatment.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Clorgyline; Desipramine; Dopamine Agonists; Ergolines; Grooming; Infusion Pumps, Implantable; Male; Monoamine Oxidase; Motor Activity; Phenelzine; Quinpirole; Rats; Rats, Sprague-Dawley; Yawning | 1995 |
Chronic administration of the antidepressants phenelzine, desipramine, clomipramine, or maprotiline decreases binding to 5-hydroxytryptamine2A receptors without affecting benzodiazepine binding sites in rat brain.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Clomipramine; Desipramine; Flunitrazepam; Fluoxetine; Ketanserin; Male; Maprotiline; Phenelzine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Effect of chronic administration of selective 5-hydroxytryptamine and noradrenaline uptake inhibitors on a putative index of 5-HT2C/2B receptor function.
Topics: Animals; Brain; Clomipramine; Desipramine; Fluoxetine; Male; Motor Activity; Norepinephrine; Paroxetine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Time Factors | 1994 |
Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder.
Topics: Animals; Clomipramine; Conditioning, Operant; Desipramine; Diazepam; Disease Models, Animal; Drinking Behavior; Fluoxetine; Haloperidol; Male; Obsessive-Compulsive Disorder; Rats; Rats, Wistar; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors | 1993 |
REM sleep deprivation potentiates the effects of imipramine and desipramine but not that of clomipramine in the forced swimming test.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Brain; Clomipramine; Desipramine; Imipramine; Male; Mice; Receptors, Adrenergic, alpha; Sleep Deprivation; Sleep, REM; Swimming; Yohimbine | 1993 |
Surface ionization organic mass spectrometry of imipramine, desipramine, clomipramine, and lidocaine.
Topics: Clomipramine; Desipramine; Humans; Imipramine; Lidocaine; Mass Spectrometry; Sensitivity and Specificity; Surface Properties | 1994 |
Effect of some neonatal treatments on the hypothalamic-pituitary-adrenocortical function.
Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Arousal; Cerebral Cortex; Clomipramine; Corticosterone; Desipramine; Dexamethasone; Emotions; Female; Hippocampus; Hypothalamo-Hypophyseal System; Male; Maternal Deprivation; Pituitary-Adrenal System; Rats; Restraint, Physical; Serotonin; Stress, Psychological | 1993 |
Effects of clonidine on desipramine- and desmethylclomipramine-induced 3-methoxy-4-hydroxyphenylglycol levels in rat brain.
Topics: Animals; Brain; Clomipramine; Clonidine; Desipramine; Drug Interactions; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Wistar | 1993 |
Chronic antidepressant drug treatment attenuates motor-suppressant effects of apomorphine without changing [3H]GBR 12935 binding.
Topics: Animals; Antidepressive Agents; Apomorphine; Brain Chemistry; Clomipramine; Desipramine; Male; Monoamine Oxidase; Motor Activity; Phenelzine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Stereotyped Behavior | 1993 |
Effects of antidepressant drug treatment on levels of NPY or prepro-NPY-mRNA in the rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Blotting, Northern; Brain; Clomipramine; Desipramine; Frontal Lobe; Hippocampus; Imipramine; Male; Neuropeptide Y; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1993 |
Postpartum obsessive compulsive disorder: a case series.
Topics: Adult; Clomipramine; Desipramine; Diagnosis, Differential; Female; Fluoxetine; Follow-Up Studies; Humans; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Psychotic Disorders; Puerperal Disorders | 1993 |
[Effects of desipramine and clomipramine on alpha 2-adrenergic receptor function in nucleus accumbens: studies with intracerebral dialysis in freely moving rats].
Topics: Adrenergic alpha-Agonists; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Clonidine; Desipramine; Dialysis; Male; Methoxyhydroxyphenylglycol; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 1995 |
TCA cardiotoxicity: the latest.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Biotransformation; Child; Clomipramine; Desipramine; Drug Interactions; Electrocardiography; Humans; Long QT Syndrome; Risk Factors | 1996 |
Characteristics of the inhibitory effect of tricyclic antidepressants on histamine release from rat peritoneal mast cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Buffers; Calcium; Clomipramine; Desipramine; Histamine Release; Imipramine; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Structure-Activity Relationship | 1996 |
Spectroscopic analysis of charge transfer complex formation and peroxidase inhibition with tricyclic antidepressant drugs: potential anti-thyroid action.
Topics: Antidepressive Agents, Tricyclic; Antithyroid Agents; Clomipramine; Desipramine; Horseradish Peroxidase; Imipramine; Iodine; Kinetics; Methimazole; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1996 |
Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat.
Topics: Amoxapine; Amygdala; Animals; Antidepressive Agents; Clomipramine; Corpus Striatum; Desipramine; Imipramine; Male; Mianserin; Radioimmunoassay; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Substance P; Substantia Nigra; Time Factors | 1996 |
Stereotypic movement disorder.
Topics: Adult; Antipsychotic Agents; Clomipramine; Desipramine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychomotor Disorders; Selective Serotonin Reuptake Inhibitors; Stereotyped Behavior; Trichotillomania | 1997 |
Neonatal treatments with the serotonin uptake inhibitors clomipramine and zimelidine, but not the noradrenaline uptake inhibitor desipramine, disrupt sleep patterns in adult rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Clomipramine; Desipramine; Electroencephalography; Male; Rats; Selective Serotonin Reuptake Inhibitors; Sleep; Zimeldine | 1997 |
Effects of clomipramine and desipramine on a C-fiber reflex in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Electric Stimulation; Injections, Intraventricular; Nerve Fibers; Rats; Rats, Sprague-Dawley | 1997 |
Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1.
Topics: Allosteric Site; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Carrier Proteins; Cell Line; Citalopram; Clomipramine; Desipramine; Humans; Imipramine; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium | 1998 |
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity | 1998 |
Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Brain Stem; Carrier Proteins; Clomipramine; Cloning, Molecular; Desipramine; DNA, Complementary; Fluoxetine; Guinea Pigs; HeLa Cells; Humans; Imipramine; Intestinal Mucosa; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Peristalsis; Polymerase Chain Reaction; Rats; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transcription, Genetic; Zimeldine | 1998 |
Generalization of D-, L- and DL-chlorpheniramine and zolantidine to the discriminative stimulus effects of cocaine and methamphetamine.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzothiazoles; Chlorpheniramine; Clomipramine; Cocaine; Desipramine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Generalization, Stimulus; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Methamphetamine; Middle Aged; Phenoxypropanolamines; Piperazines; Piperidines; Rats; Rats, Inbred F344; Thiazoles | 1997 |
Effects of psychoactive drugs on temporal discrimination in rats.
Topics: Animals; Atropine; Clomipramine; Desipramine; Diazepam; Discrimination Learning; Discrimination, Psychological; Haloperidol; Male; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar; Scopolamine | 1997 |
The effect of chronic administration of antidepressants on the circadian pattern of corticosterone in the rat.
Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clomipramine; Corticosterone; Desipramine; Hypothalamo-Hypophyseal System; Imipramine; Male; Phenelzine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley | 1998 |
Effect of psychotropic drugs on taste responses in young and elderly persons.
Topics: Adult; Aged; Aging; Amitriptyline; Clomipramine; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Psychotropic Drugs; Taste; Trifluoperazine | 1998 |
Nonaqueous capillary electrophoretic separation and thermo-optical absorbance detection of five tricyclic antidepressants and metabolism of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Molecular Structure; Nortriptyline | 1998 |
On-line nonaqueous capillary electrophoresis and electrospray mass spectrometry of tricyclic antidepressants and metabolic profiling of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Calibration; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Mass Spectrometry; Molecular Structure | 1998 |
Treating imagined ugliness.
Topics: Adrenergic Uptake Inhibitors; Clomipramine; Desipramine; Double-Blind Method; Female; Humans; Male; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Somatoform Disorders; Treatment Outcome | 1999 |
Long photoperiod regimen may produce antidepressant actions in the male rat.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Conditioning, Operant; Depression; Desipramine; Male; Photoperiod; Rats; Rats, Wistar; Reinforcement Schedule; Swimming | 2000 |
The differential effects of calcium channel blockers in the behavioural despair test in mice.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; Depression; Desipramine; Diltiazem; Drug Interactions; Female; Male; Mianserin; Mice; Motor Activity; Nifedipine; Tranylcypromine; Verapamil | 2000 |
Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro.
Topics: Animals; Antidepressive Agents; Brain; Cell Division; Cells, Cultured; Cerebellum; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Nervous System; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Thymidine | 2001 |
Development of a depersonalization severity scale.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Depersonalization; Desipramine; Discriminant Analysis; Female; Fluoxetine; Humans; Interview, Psychological; Male; Observer Variation; Psychiatric Status Rating Scales; Psychometrics; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2001 |
Differential time-course profiles of dopamine release and uptake changes induced by three dopamine uptake inhibitors.
Topics: Adrenergic Uptake Inhibitors; Animals; Benzazepines; Brain Chemistry; Clomipramine; Cocaine; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sulpiride | 2001 |
Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder.
Topics: Adrenergic Uptake Inhibitors; Aggression; Animals; Arginine Vasopressin; Behavior, Animal; Clomipramine; Cricetinae; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Grooming; Hair; Hypothalamus; Male; Microinjections; Obsessive-Compulsive Disorder; Pigmentation; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 2001 |
Clomipramine and related structures as inhibitors of the skeletal sarcoplasmic reticulum Ca2+ pump.
Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Calcium; Calcium-Transporting ATPases; Clomipramine; Desipramine; Enzyme Inhibitors; Imipramine; Magnesium; Muscle, Skeletal; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Trimipramine | 2000 |
Mimosa pudica may possess antidepressant actions in the rat.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Desipramine; Fabaceae; Male; Medicine, Traditional; Mexico; Phytotherapy; Plant Extracts; Plants, Medicinal; Psychological Tests; Rats; Rats, Wistar; Stress, Physiological; Swimming | 1999 |
Age differences in the sensitivity to clomipramine in an animal model of obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Male; Obsessive-Compulsive Disorder; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Cortical alpha-adrenoceptor downregulation by tricyclic antidepressants in the rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Down-Regulation; Hippocampus; Imipramine; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
Testosterone-dependent antidepressant-like effect of noradrenergic but not of serotonergic drugs.
Topics: Adrenergic Agents; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Clomipramine; Desipramine; Female; Fluoxetine; Male; Motor Activity; Norepinephrine; Orchiectomy; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Swimming; Testosterone | 2004 |
Chronic treatment with clomipramine and desipramine induces deficit in long-term visuo-spatial memory of rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Desipramine; Maze Learning; Memory Disorders; Rats; Rats, Long-Evans; Space Perception | 2005 |
Antidepressant treatment reduces Fos-like immunoreactivity induced by swim stress in different columns of the periaqueductal gray matter.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Cell Count; Clomipramine; Desipramine; Disease Models, Animal; Immobility Response, Tonic; Male; Oncogene Proteins v-fos; Periaqueductal Gray; Rats; Rats, Wistar; Stress, Psychological; Swimming | 2006 |
The effects of antidepressants on cyclic AMP-response element-driven gene transcription in a model cell system.
Topics: Alkaline Phosphatase; Animals; Antidepressive Agents, Tricyclic; Blotting, Western; CHO Cells; Clomipramine; Cricetinae; Cricetulus; Cyclic AMP Response Element-Binding Protein; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Genes, Reporter; Humans; Receptors, Adrenergic, beta-2; Thiazepines; Time Factors; Transcription, Genetic | 2007 |
Analysis of tricyclic antidepressant drugs in plasma by means of solid-phase microextraction-liquid chromatography-mass spectrometry.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Chromatography, Liquid; Clomipramine; Desipramine; Humans; Imipramine; Nortriptyline; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2007 |
Toluene has antidepressant-like actions in two animal models used for the screening of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Hindlimb Suspension; Ketamine; Male; Mice; Motor Activity; Psychomotor Performance; Solvents; Swimming; Toluene | 2009 |
Effects of antidepressants on the performance in the forced swim test of two psychogenetically selected lines of rats that differ in coping strategies to aversive conditions.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Clomipramine; Depression; Desipramine; Disease Models, Animal; Fluoxetine; Genetics, Behavioral; Phenotype; Rats; Rats, Inbred Strains; Stress, Psychological; Swimming | 2010 |
The effects of antidepressants on mitochondrial function in a model cell system and isolated mitochondria.
Topics: Animals; Antidepressive Agents; CHO Cells; Clomipramine; Cricetinae; Cricetulus; Desipramine; Electron Transport Chain Complex Proteins; Fluoxetine; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Oxygen Consumption; Rats; Rats, Wistar; Thiazepines | 2011 |
Predictive validity of a non-induced mouse model of compulsive-like behavior.
Topics: Animals; Anxiety; Behavior, Animal; Clomipramine; Compulsive Behavior; Desipramine; Disease Models, Animal; Exploratory Behavior; Fluoxetine; Male; Maze Learning; Mice; Mice, Inbred Strains; Motor Activity; Nesting Behavior | 2011 |
Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clomipramine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Female; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Iodocyanopindolol; Isotopes; Mice; Mice, Inbred BALB C; Neural Inhibition; Obsessive-Compulsive Disorder; Prefrontal Cortex; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Swimming; Time Factors | 2011 |
Reactive metabolites of desipramine and clomipramine: The kinetics of formation and reactivity with DNA.
Topics: Antidepressive Agents; Biocatalysis; Clomipramine; Desipramine; DNA; Horseradish Peroxidase; Hydrogen Peroxide; Kinetics; Oxidation-Reduction | 2012 |
Comparative evaluation of the effect of tricyclic antidepressants on inducible nitric oxide synthase expression in neuropathic pain model.
Topics: Amitriptyline; Analgesics; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cerebellum; Clomipramine; Desipramine; Enzyme Inhibitors; Gene Expression; Guanidines; Hippocampus; Immunohistochemistry; Male; Neuralgia; Nitric Oxide Synthase Type II; Pain Measurement; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve | 2012 |
Effects of chronic antidepressant treatments in a putative genetic model of vulnerability (Roman low-avoidance rats) and resistance (Roman high-avoidance rats) to stress-induced depression.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Clomipramine; Data Interpretation, Statistical; Depression; Desipramine; Fluoxetine; Male; Motor Activity; Rats; Selective Serotonin Reuptake Inhibitors; Species Specificity; Stress, Psychological; Swimming | 2014 |
Interaction of different antidepressants with acute and chronic methadone in mice, and possible clinical implications.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Citalopram; Clomipramine; Cyclohexanols; Desipramine; Drug Interactions; Fluvoxamine; Male; Methadone; Mice; Mice, Inbred ICR; Morpholines; Nociception; Pain Threshold; Reboxetine; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride | 2014 |
d-Amphetamine and methylmercury exposure during adolescence alters sensitivity to monoamine uptake inhibitors in adult mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Biogenic Monoamines; Clomipramine; Conditioning, Operant; Desipramine; Dextroamphetamine; Male; Methylmercury Compounds; Mice, Inbred C57BL; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors | 2019 |