desipramine and chlorprothixene

desipramine has been researched along with chlorprothixene in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199017 (70.83)18.7374
1990's0 (0.00)18.2507
2000's4 (16.67)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Gozalbes, R; Pineda-Lucena, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Frisk-Holmberg, M; van der Kleijn, E1
Zingales, I1
Berndt, S; Schwabe, U1
Boulu, R; Dupeyron, JP; Rossignol, P1
Broeren, W; Schmitt, W1
Mainard, F; Stephan, Y; Welin, L1
Scheel-Krüger, J1
Hitomi, M; Kumada, S; Kumadaki, N1
Burghardt, C; Sheppard, H; Tsien, WH1
Heilig, P; Heiss, WD; Hoyer, J2
GYERMEK, L; SIGG, EB; SOFFER, L1
HALLIWELL, G; QUINTON, RM; WILLIAMS, FE1
JACOBSON, J; URSILLO, RC1
METYS, J; METYSOVA, J; VOTAVA, Z1

Trials

1 trial(s) available for desipramine and chlorprothixene

ArticleYear
[Psychopharmacological experiment as a contribution to pharmacopsychiatric basic research].
    Der Nervenarzt, 1968, Volume: 39, Issue:11

    Topics: Chlorprothixene; Clinical Trials as Topic; Desipramine; Humans; Personality; Psychopharmacology; Thioridazine; Tranquilizing Agents

1968

Other Studies

23 other study(ies) available for desipramine and chlorprothixene

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
Systematic identification of psychotropic drugs by thin layer chromatography. II.
    Journal of chromatography, 1968, Mar-26, Volume: 34, Issue:1

    Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Humans; Imipramine; Male; Meprobamate; Nortriptyline; Phenothiazines; Schizophrenia; Silicon Dioxide; Thioridazine; Tranquilizing Agents

1968
Effect of psychotropic drugs on phosphodiesterase and cyclic AMP level in rat brain in vivo.
    Brain research, 1973, Dec-07, Volume: 63

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlorpromazine; Chlorprothixene; Cyclic AMP; Desipramine; Haloperidol; Imipramine; Male; Phosphoric Diester Hydrolases; Rats; Theophylline; Tranquilizing Agents; Triflupromazine; Tritium

1973
[Evaluation of central antireserpine effect by the use of light blink reflex (author's transl)].
    Psychopharmacologia, 1973, Oct-23, Volume: 33, Issue:1

    Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Diethylamines; Dimethylamines; Ethylenediamines; Glycolates; Imipramine; Light; Nortriptyline; Propylamines; Rabbits; Reflex; Reserpine

1973
[Binding to human serum proteins of drugs belonging to phenothiazine series, iminodibenzyle, thioxanthene and thiophenylpyridylamine].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Mar-08, Volume: 272, Issue:10

    Topics: Antidepressive Agents; Blood Proteins; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Chromatography, Gel; Desipramine; Dibenzazepines; Humans; Imipramine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Protein Binding; Spectrophotometry; Thiazines; Trimeprazine

1971
Studies on the accumulation of O-methylated dopamine and noradrenaline in the rat brain following various neuroleptics, thymoleptics and aceperone.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 195, Issue:2

    Topics: Acetamides; Animals; Antidepressive Agents; Benzimidazoles; Brain; Brain Chemistry; Butyrophenones; Chlorpromazine; Chlorprothixene; Desipramine; Dopamine; Imipramine; Ketones; Male; Methylation; Norepinephrine; Normetanephrine; Pargyline; Piperidines; Rats; Stimulation, Chemical; Tranquilizing Agents; Tyramine

1972
Effect of psychotherapeutic drugs on hyperemotionality of rats in which the olfactory bulb was removed.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:4

    Topics: Amitriptyline; Animals; Benperidol; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Desipramine; Emotions; Imipramine; Limbic System; Male; Meprobamate; Phenobarbital; Rats; Reserpine; Tranquilizing Agents

1967
Effect of drugs on the hemolysis of rat erythrocytes.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Animals; Aspirin; Bile Acids and Salts; Chlordiazepoxide; Chloroquine; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Desoxycorticosterone; Digitalis Glycosides; Diuretics; Erythrocytes; Glucose; Guanethidine; Hemolysis; Hydrocortisone; Hypotonic Solutions; Indomethacin; Levorphanol; Male; Neostigmine; Rats; Tripelennamine

1969
[The influence of psychopharmacologic agents on the acitvity of retinal neurons].
    Vision research, 1969, Volume: 9, Issue:4

    Topics: Action Potentials; Amitriptyline; Animals; Cats; Chlorpromazine; Chlorprothixene; Desipramine; Diazepam; Neurons; Optic Nerve; Retina; Tranquilizing Agents

1969
[The influence of psychopharmacologic agents on visual evoked potentials in the cat].
    Vision research, 1969, Volume: 9, Issue:4

    Topics: Amitriptyline; Animals; Cats; Cerebral Cortex; Chlorpromazine; Chlorprothixene; Desipramine; Diazepam; Evoked Potentials; Haloperidol; Tranquilizing Agents; Vision, Ocular; Visual Cortex

1969
INFLUENCE OF IMIPRAMINE AND RELATED PSYCHOACTIVE AGENTS ON THE EFFECT OF 5-HYDROXYTRYPTAMINE AND CATECHOLAMINES ON THE CAT NICTITATING MEMBRANE.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142

    Topics: Amitriptyline; Animals; Antidepressive Agents; Catecholamines; Cats; Chlorpromazine; Chlorprothixene; Desipramine; Epinephrine; Imipramine; Nictitating Membrane; Norepinephrine; Pharmacology; Promazine; Psychotropic Drugs; Research; Serotonin; Tranquilizing Agents

1963
A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.
    British journal of pharmacology and chemotherapy, 1964, Volume: 23

    Topics: Alcoholic Intoxication; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Autonomic Nervous System; Bradycardia; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Desipramine; Dogs; Epinephrine; Imipramine; Mice; Norepinephrine; Pharmacology; Promazine; Rats; Research; Reserpine; Sleep; Toxicology; Tranquilizing Agents; Vasomotor System; Yohimbine

1964
POTENTIATION OF NOREPINEPHRINE IN THE ISOLATED VAS DEFERENS OF THE RAT BY SOME CNS STIMULANTS AND ANTIDEPRESSANTS.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Humans; Imipramine; Male; Methylphenidate; Norepinephrine; Pharmacology; Phenmetrazine; Piperidines; Rats; Research; Tranquilizing Agents; Vas Deferens

1965
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlorpromazine; Chlorprothixene; Desipramine; Eyelids; Imipramine; Mice; Nortriptyline; Peptic Ulcer; Pharmacology; Rats; Research; Reserpine; Toxicology; Tranquilizing Agents

1964