desipramine and benztropine

desipramine has been researched along with benztropine in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (72.50)	18.7374
1990's	5 (12.50)	18.2507
2000's	2 (5.00)	29.6817
2010's	4 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Dawes, P; Redfern, PH	1
Richelson, E	1
Aghajanian, GK; Bunney, BS	2
Broch, OJ	1
Ghosh, PK; Hrdina, PD	1
Bertollini, A; del Carmine, R; Levi, G; Raiteri, M	1
Berger, B; Blanc, G; Glowinski, J; Stinus, L; Tassin, JP; Thierry, AM	1
Barker, JL; di Porzio, U; Fiszman, ML; Masana, MI; Zuddas, A	1
Dubner, R; Gracely, RH; Kishore-Kumar, R; Max, MB; Meister, B; Schafer, SC; Smoller, B	1
Chilco, PJ; Donnan, GA; Kaczmarczyk, SJ; Kalnins, RM; Mendelsohn, FA; Paxinos, G; Woodhouse, DG	1
Bell, C; Harris, PJ; Sunn, N	1
Audet, MA; Descarries, L; Doucet, G; Oleskevich, S	1
Cavicchia, S; Dewey, DA; DiJohnson, C; Kimes, I; Kramer, MS; Little, P; Schmidt, R; Sheves, P; Vogel, WH	1
Ahnert-Hilger, G; Engele, J; Pilgrim, C; Reisert, I	1
Descarries, L; Doucet, G; Garcia, S	1
Marsden, CA; Routledge, C	1
Cho, AK; Howard, BD; Koide, M	1
Soares-da-Silva, P	1
Squires, RF	1
Blanc, G; Glowinski, J; Tassin, JP; Thierry, AM	1
Blanc, G; Glowinski, J; Hirsch, JC; Tassin, JP; Thierry, AM	1
Andersen, PR; Gibbs, P; Kubinski, H	1
Carmichael, FJ; Israel, Y	1
Cuello, AC; Horn, AS; Iversen, LL; Mackay, AV	1
Scheel-Krüger, J	1
Hernandez, L; Hoebel, BG	1
Gladfelter, WE; Heym, J	1
Katz, IR	1
Harik, SI; Logan, WJ	1
Bell, C	1
Petrali, EH	1
Bartone, P; Carter, M; Cooley, S; DiBarry, AL; Hammill, K; Hogarty, GE; McEvoy, JP; Munetz, MR; Perel, J; Ulrich, RF	1

Reviews

2 review(s) available for desipramine and benztropine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Electrophysiological studies of dopamine- innervated cells in the frontal cortex. Advances in biochemical psychopharmacology, 1977, Volume: 16 Topics: Animals; Benztropine; Cerebral Cortex; Desipramine; Dopamine; Drug Interactions; Electrophysiology; Hippocampus; Histocytochemistry; Horseradish Peroxidase; Iontophoresis; Neural Pathways; Norepinephrine; Rats; Trifluoperazine	1977

Trials

3 trial(s) available for desipramine and benztropine

Article	Year
Efficacy of desipramine in painful diabetic neuropathy: a placebo-controlled trial. Pain, 1991, Volume: 45, Issue:1 Topics: Adult; Aged; Benztropine; Depression; Desipramine; Diabetic Neuropathies; Double-Blind Method; Emotions; Female; Humans; Male; Middle Aged; Pain	1991
Antidepressants in 'depressed' schizophrenic inpatients. A controlled trial. Archives of general psychiatry, 1989, Volume: 46, Issue:10 Topics: Adolescent; Adult; Amitriptyline; Benztropine; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Hospitalization; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology	1989
Pharmacotherapy of impaired affect in recovering schizophrenic patients. Archives of general psychiatry, 1995, Volume: 52, Issue:1 Topics: Adolescent; Adult; Ambulatory Care; Antipsychotic Agents; Anxiety Disorders; Basal Ganglia Diseases; Benztropine; Depressive Disorder; Desipramine; Diagnosis, Differential; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fluphenazine; Glycopyrrolate; Humans; Lithium Carbonate; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Sex Factors	1995

Other Studies

35 other study(ies) available for desipramine and benztropine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Changes in the conditiond avoidance behaviour of rats following the administration of drugs to the amygdala [proceedings]. The Journal of pharmacy and pharmacology, 1976, Volume: 28 Suppl Topics: Amygdala; Animals; Apomorphine; Avoidance Learning; Benztropine; Conditioning, Psychological; Desipramine; Dextroamphetamine; Haloperidol; Male; Rats	1976
Tricyclic antidepressants and histamine H1 receptors. Mayo Clinic proceedings, 1979, Volume: 54, Issue:10 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic	1979
In vivo effects of benztropine and nomifensine on dopamine and noradrenaline terminals in rat brain. European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4 Topics: Amphetamine; Animals; Benztropine; Brain; Corpus Striatum; Desipramine; Dopamine; Drug Interactions; Hydroxydopamines; Isoquinolines; Male; Nomifensine; Norepinephrine; Rats; Synaptosomes; Tropanes	1979
Effects of tricyclic antidepressants on the content and metabolism of dopamine in the rat striatum. Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Benztropine; Corpus Striatum; Desipramine; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Imipramine; Male; Rats; Time Factors	1977
Release of biogenic amines from isolated nerve endings. Advances in experimental medicine and biology, 1976, Volume: 69 Topics: Amphetamine; Animals; Benztropine; Benzylamines; Biogenic Amines; Brain; Calcium; Corpus Striatum; Desipramine; Dopamine; Hypothalamus; Nerve Endings; Norepinephrine; Phenethylamines; Rats; Reserpine; Serotonin; Synaptosomes	1976
Transport of dopamine in discrete areas of the striatum and of cerebral cortex in the rat. Advances in experimental medicine and biology, 1976, Volume: 69 Topics: Animals; Benztropine; Biological Transport, Active; Cerebral Cortex; Corpus Striatum; Desipramine; Dopamine; Hydroxydopamines; Norepinephrine; Rats	1976
Dopamine and norepinephrine innervated cells in the rat prefrontal cortex: pharmacological differentiation using microiontophoretic techniques. Life sciences, 1976, Dec-01, Volume: 19, Issue:11 Topics: Action Potentials; Animals; Benztropine; Brain Mapping; Cerebral Cortex; Desipramine; Dopamine; Drug Synergism; Hippocampus; Male; Norepinephrine; Olfactory Bulb; Rats; Trifluoperazine	1976
Dopamine synthesis precedes dopamine uptake in embryonic rat mesencephalic neurons. Journal of neurochemistry, 1991, Volume: 56, Issue:2 Topics: Animals; Benztropine; Catechol O-Methyltransferase; Corpus Striatum; Desipramine; Dopamine; Fluorescent Antibody Technique; Mesencephalon; Monoamine Oxidase; Neurons; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase	1991
Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography. The Journal of comparative neurology, 1991, Feb-15, Volume: 304, Issue:3 Topics: Aged; Benztropine; Binding, Competitive; Biological Transport; Brain Chemistry; Brain Mapping; Caudate Nucleus; Citalopram; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Humans; Locus Coeruleus; Mazindol; Medulla Oblongata; Mianserin; Middle Aged; Norepinephrine; Piperazines; Pons; Substantia Nigra	1991
Effects on renal sympathetic axons in dog of acute 6-hydroxydopamine treatment in combination with selective neuronal uptake inhibitors. British journal of pharmacology, 1990, Volume: 99, Issue:4 Topics: Animals; Axons; Benztropine; Blood Pressure; Catecholamines; Desipramine; Dogs; Electric Stimulation; Female; Heart Rate; Hydroxydopamines; Kidney; Kidney Function Tests; Male; Neurotransmitter Uptake Inhibitors; Oxidopamine; Sympathectomy, Chemical; Sympathetic Nervous System	1990
Quantified regional and laminar distribution of the noradrenaline innervation in the anterior half of the adult rat cerebral cortex. The Journal of comparative neurology, 1988, Aug-15, Volume: 274, Issue:3 Topics: Animals; Autoradiography; Axonal Transport; Benztropine; Cerebral Cortex; Citalopram; Desipramine; Dopamine; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Inbred Strains; Reference Values; Tritium	1988
Different developmental schedules of dopaminergic and noradrenergic neurons in dissociation culture of fetal rat midbrain and hindbrain. Neuroscience, 1986, Volume: 17, Issue:1 Topics: Adrenergic Fibers; Animals; Autoradiography; Benztropine; Brain; Cells, Cultured; Desipramine; Dopamine; Mesencephalon; Norepinephrine; Rats; Synaptic Transmission	1986
Quantification of the dopamine innervation in adult rat neostriatum. Neuroscience, 1986, Volume: 19, Issue:2 Topics: Animals; Autoradiography; Axons; Benztropine; Citalopram; Corpus Striatum; Desipramine; Dopamine; Hydroxydopamines; Male; Nerve Endings; Oxidopamine; Propylamines; Rats; Rats, Inbred Strains	1986
Lack of selectivity between the uptake of [3H]adrenaline and [3H]noradrenaline into rat hypothalamic slices. Journal of neurochemistry, 1987, Volume: 49, Issue:3 Topics: Animals; Benztropine; Desipramine; Epinephrine; Fluoxetine; Hypothalamus; Male; Maprotiline; Norepinephrine; Rats; Rats, Inbred Strains; Tissue Distribution	1987
Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells. Journal of neurochemistry, 1986, Volume: 47, Issue:4 Topics: Adrenal Gland Neoplasms; Animals; Benztropine; Binding, Competitive; Biological Transport; Carrier Proteins; Catecholamine Plasma Membrane Transport Proteins; Cell Line; Cocaine; Desipramine; Dopamine; Kinetics; Membrane Transport Proteins; Molecular Weight; Nitrogen Mustard Compounds; Norepinephrine; Pheochromocytoma; Proteins; Rats; Sodium	1986
Evidence for a non-precursor dopamine pool in noradrenergic neurones of the dog mesenteric artery. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:3 Topics: Animals; Benztropine; Biological Transport, Active; Desipramine; Disulfiram; Dogs; Dopamine; Dopamine beta-Hydroxylase; Female; Kinetics; Male; Mesenteric Arteries; Neurons; Norepinephrine	1986
Effects of noradrenaline pump blockers on its uptake by synaptosomes from several brain regions; additional evidence for dopamine terminals in the frontal cortex. The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:5 Topics: Amitriptyline; Animals; Benztropine; Biological Transport, Active; Carbon Radioisotopes; Cerebral Cortex; Desipramine; Dibenzazepines; Dopamine; Frontal Lobe; Imipramine; Mice; Norepinephrine; Synaptosomes; Tritium	1974
Evidence for a specific uptake of dopamine by dopaminergic terminals of the rat cerebral cortex. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:3 Topics: Animals; Benztropine; Cerebellum; Cerebral Cortex; Chemoreceptor Cells; Corpus Striatum; Desipramine; Dopamine; Dopamine Antagonists; Hydroxydopamines; Male; Nerve Endings; Neurons; Neurons, Efferent; Rats; Tritium	1974
Presence of dopaminergic terminals and absence of dopaminergic cell bodies in the cerebral cortex of the cat. Brain research, 1974, Oct-11, Volume: 79, Issue:1 Topics: Absorption; Animals; Benztropine; Cats; Caudate Nucleus; Cerebellar Cortex; Cerebral Cortex; Depression, Chemical; Desipramine; Dopamine; Drug Synergism; Male; Nerve Endings; Norepinephrine; Rats; Rats, Inbred Strains; Tritium; Tyrosine	1974
Effects of neuropharmacological agents on in vitro formation of complexes between nucleic acids and proteins. Neuropharmacology, 1974, Volume: 13, Issue:2 Topics: Animals; Benztropine; Cattle; Chlorpromazine; Codeine; Desipramine; DNA, Bacterial; Escherichia coli; Histones; Lysergic Acid Diethylamide; Morphine; Neostigmine; Nucleic Acids; Orphenadrine; Phenytoin; Protein Binding; Proteins; RNA, Bacterial; RNA, Ribosomal; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Trihexyphenidyl	1974
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2 Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium	1973
Letter: Catecholamines in the median eminence: new evidence for a major noradrenergic input. Nature, 1973, Jun-22, Volume: 243, Issue:5408 Topics: Animals; Benztropine; Corpus Striatum; Depression, Chemical; Desipramine; Dopamine; Hypothalamo-Hypophyseal System; Male; Methods; Methylation; Methyltransferases; Microscopy, Fluorescence; Nerve Endings; Norepinephrine; Rats; Temperature; Tritium	1973
Behavioural and biochemical comparison of amphetamine derivatives, cocaine, benztropine and tricyclic anti-depressant drugs. European journal of pharmacology, 1972, Volume: 18, Issue:1 Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Benztropine; Brain; Brain Chemistry; Cocaine; Desipramine; Dopamine; Imipramine; Iproniazid; Male; Motor Activity; Nialamide; Norepinephrine; Normetanephrine; Parasympatholytics; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tropanes; Tyramine	1972
Overeating after midbrain 6-hydroxydopamine: prevention by central injection of selective catecholamine reuptake blockers. Brain research, 1982, Aug-12, Volume: 245, Issue:2 Topics: Animals; Benztropine; Desipramine; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Eating; Female; Hydroxydopamines; Mesencephalon; Muridae; Norepinephrine; Oxidopamine; Premedication; Tropanes	1982
Serotonergic innervation of the lateral hypothalamus: evidence from synaptosomal uptake studies. Brain research bulletin, 1982, Volume: 8, Issue:2 Topics: Absorption; Animals; Benztropine; Desipramine; Female; Fluoxetine; Hypothalamus; Kinetics; Mesencephalon; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes	1982
Monoamine oxidase-catalyzed metabolism of 3,4-dihydroxyphenylethylamine in the dopaminergic synaptosomes from rat corpus striatum. Journal of neurochemistry, 1982, Volume: 38, Issue:3 Topics: Animals; Benztropine; Clomipramine; Clorgyline; Corpus Striatum; Desipramine; Dopamine; Kinetics; Male; Monoamine Oxidase; Pargyline; Rats; Rats, Inbred Strains; Synaptosomes	1982
Specific uptake of norepinephrine and dopamine by homogenates of rat cerebral cortex after locus ceruleus lesion. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1982, Volume: 2, Issue:3 Topics: Animals; Benztropine; Cerebral Cortex; Culture Techniques; Denervation; Desipramine; Dominance, Cerebral; Dopamine; Dopamine Antagonists; Locus Coeruleus; Male; Neural Pathways; Norepinephrine; Rats; Rats, Inbred Strains; Synaptic Vesicles	1982
Benztropine-induced prolongation of responses to vasodilator nerve stimulation in the canine paw pad. British journal of pharmacology, 1982, Volume: 76, Issue:2 Topics: Animals; Benztropine; Desipramine; Dogs; Electric Stimulation; Foot; Guanethidine; Regional Blood Flow; Time Factors; Tropanes; Vasodilation; Vasomotor System	1982
Differential effects of benztropine and desipramine on the high affinity uptake of paratyramine in slices of the caudate nucleus and hypothalamus. Neurochemical research, 1980, Volume: 5, Issue:3 Topics: Animals; Benztropine; Biological Transport; Caudate Nucleus; Desipramine; Dopamine; Hypothalamus; Male; Rats; Tropanes; Tyramine	1980