desipramine and amoxapine

desipramine has been researched along with amoxapine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's2 (11.76)18.2507
2000's1 (5.88)29.6817
2010's7 (41.18)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM1
Ahman, M; Holmén, AG; Wan, H1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL1
Davidson, R; Dilsaver, SC1
Mahapatra, D; Mahapatra, RK; Paul, SK; Winter, S1
Narasimhachari, N1
Peterson, SL; St Mary, JS; Trzeciakowski, JP1
Anton, RF; Randall, CL; Sexauer, JD1
Itoh, M; Nakao, H; Notomi, A; Yufu, N1
Ichikawa, H; Mitsushio, H; Shirayama, Y; Takahashi, K; Takashima, M1

Reviews

1 review(s) available for desipramine and amoxapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for desipramine and amoxapine

ArticleYear
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship

1999
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
    RSC medicinal chemistry, 2022, Feb-23, Volume: 13, Issue:2

    Topics:

2022
Cholinergic properties of desipramine and amoxapine: assessment using a thermoregulation paradigm.
    Progress in neuro-psychopharmacology & biological psychiatry, 1987, Volume: 11, Issue:5

    Topics: Amoxapine; Animals; Body Temperature Regulation; Desipramine; Dibenzoxazepines; Dose-Response Relationship, Drug; Hypothalamus; Male; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic

1987
Cardiovascular effects of polycyclic antidepressants.
    Angiology, 1986, Volume: 37, Issue:10

    Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depression; Desipramine; Doxepin; Female; Heart; Humans; Imipramine; Male; Middle Aged

1986
Tricyclic antidepressants in vivo methylation: response to Lydiard and co-workers.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:1

    Topics: Amoxapine; Animals; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Kinetics; Loxapine; Methylation; Rabbits

1986
Chronic but not acute treatment with antidepressants enhances the electroconvulsive seizure response in rats.
    Neuropharmacology, 1985, Volume: 24, Issue:10

    Topics: Amoxapine; Animals; Antidepressive Agents; Clomipramine; Convulsants; Desipramine; Electric Stimulation; Male; Mianserin; Pargyline; Rats; Rats, Inbred Strains; Seizures

1985
Amoxapine elevates serum prolactin in depressed men.
    Journal of affective disorders, 1983, Volume: 5, Issue:4

    Topics: Amoxapine; Bipolar Disorder; Depressive Disorder; Desipramine; Dibenzoxazepines; Humans; Male; Middle Aged; Prolactin; Receptors, Dopamine

1983
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
    Folia psychiatrica et neurologica japonica, 1984, Volume: 38, Issue:1

    Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline

1984
Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat.
    Brain research, 1996, Nov-11, Volume: 739, Issue:1-2

    Topics: Amoxapine; Amygdala; Animals; Antidepressive Agents; Clomipramine; Corpus Striatum; Desipramine; Imipramine; Male; Mianserin; Radioimmunoassay; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Substance P; Substantia Nigra; Time Factors

1996