desipramine and 1-methyl-4-phenylpyridinium

desipramine has been researched along with 1-methyl-4-phenylpyridinium in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's9 (42.86)18.2507
2000's7 (33.33)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gambaryan, S; Gorboulev, V; Gründemann, D; Koepsell, H; Veyhl, M1
Akhoundova, A; Baumann, C; Busch, AE; Gorboulev, V; Karbach, U; Koepsell, H; Lang, F; Quester, S; Ulzheimer, JC; Ulzheimer-Teuber, I1
Fei, YJ; Ganapathy, V; Kekuda, R; Leibach, FH; Prasad, PD; Wang, H; Wu, X1
Giacomini, KM; Schaner, ME; Zhang, L1
Chen, J; Conway, SJ; Fei, YJ; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wu, X1
Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X1
Conway, SJ; Ganapathy, V; George, RL; Huang, W; Leibach, FH; Wang, H; Wu, X1
Conway, SJ; Ganapathy, ME; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wang, H; Wu, X1
Akhoundova, A; Arndt, P; Bamberg, E; Budiman, T; Gorboulev, V; Koepsell, H; Koppatz, S; Nagel, G; Popp, C; Ulzheimer-Teuber, I; Volk, C1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Daniels, AJ; Painter, GR; Reinhard, JF1
Arai, Y; Kinemuchi, H; Kisara, K; Matsumura, T; Sakuma, I; Satoh, N; Tadano, T1
Daniels, AJ; Diliberto, EJ; Reinhard, JF; Viveros, OH1
Fuller, RW; Hemrick-Luecke, SK; Robertson, DW1
Jonsson, G; Luthman, J1
Caron, MG; Giros, B; Hornykiewicz, O; Pifl, C1
Levi, R; Smith, NC1
Keating, E; Martel, F1
Hillard, CJ; Kalyanaraman, B; Shang, T; Uihlein, AV; Van Asten, J1
Chetsawang, B; Chetsawang, J; Govitrapong, P1

Other Studies

21 other study(ies) available for desipramine and 1-methyl-4-phenylpyridinium

ArticleYear
Drug excretion mediated by a new prototype of polyspecific transporter.
    Nature, 1994, Dec-08, Volume: 372, Issue:6506

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cations; Cells, Cultured; DNA, Complementary; Intestinal Mucosa; Kidney Tubules, Proximal; Liver; Membrane Proteins; Molecular Sequence Data; Organic Cation Transporter 1; Pharmacokinetics; Recombinant Proteins; RNA, Messenger; Xenopus

1994
Cloning and characterization of two human polyspecific organic cation transporters.
    DNA and cell biology, 1997, Volume: 16, Issue:7

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cations; Cell Membrane; Cloning, Molecular; Electric Conductivity; Humans; Ion Transport; Kidney Cortex; Kidney Tubules, Distal; Kinetics; Liver; Membrane Proteins; Molecular Sequence Data; Oocytes; Organ Specificity; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis

1997
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta.
    The Journal of biological chemistry, 1998, Jun-26, Volume: 273, Issue:26

    Topics: Amino Acid Sequence; Animals; Cloning, Molecular; DNA-Binding Proteins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Octamer Transcription Factor-3; Oocytes; Placenta; Protein Conformation; Rats; Transcription Factors; Xenopus laevis

1998
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection

1998
Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.
    The Journal of biological chemistry, 1998, Dec-04, Volume: 273, Issue:49

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biogenic Monoamines; Brain; Carrier Proteins; Cell Line; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Neurotoxins; Neurotransmitter Agents; Oocytes; Rats; Xenopus laevis

1998
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium

1999
Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta.
    Biochimica et biophysica acta, 2000, Jun-01, Volume: 1466, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Proteins; Structure-Activity Relationship; Symporters; Tetraethylammonium; Tissue Distribution

2000
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Binding, Competitive; Carbon Radioisotopes; Cations; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Dopamine Agents; Exons; Gene Expression Regulation; HeLa Cells; Herbicides; Humans; In Situ Hybridization; Introns; Kidney; Mice; Niacinamide; Octamer Transcription Factor-3; Oocytes; Pigment Epithelium of Eye; RNA, Messenger; Tetraethylammonium; Transcription Factors; Tritium; Xenopus laevis

2000
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:3

    Topics: Animals; Anions; Carrier Proteins; Cations; Cell Line; Cell Membrane; Choline; Cloning, Molecular; Female; Guanidine; Histamine; Humans; In Vitro Techniques; Kidney; Kinetics; Membrane Potentials; Membrane Proteins; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Transfection; Xenopus laevis

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Carrier-independent entry of 1-methyl-4-phenylpyridinium (MPP+) into adrenal chromaffin cells as a consequence of charge delocalization.
    Biochemical and biophysical research communications, 1990, May-16, Volume: 168, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Adrenal Medulla; Animals; Cattle; Cells, Cultured; Chromaffin System; Desipramine; Diffusion; Electrochemistry; L-Lactate Dehydrogenase; Molecular Structure

1990
Behavioral and biochemical changes following acute administration of MPTP and MPP+.
    Life sciences, 1987, Mar-30, Volume: 40, Issue:13

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Desipramine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Nomifensine; Pyridines; Pyridinium Compounds; Selegiline; Serotonin

1987
Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:22

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Cell Compartmentation; Cells, Cultured; Desipramine; Digitonin; Drug Interactions; Nicotine; Pyridines; Pyridinium Compounds; Subcellular Fractions; Tetrabenazine; Tyrosine 3-Monooxygenase

1987
Comparison of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium (MPP+) effects on mouse heart norepinephrine.
    Biochemical pharmacology, 1988, Sep-01, Volume: 37, Issue:17

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Bridged Bicyclo Compounds; Cerebral Cortex; Corpus Striatum; Desipramine; Heart; Hydroxydopamines; Male; Mice; Norepinephrine; Oxidopamine; Pyridines; Pyridinium Compounds; Spleen; Time Factors

1988
Effects of the parkinsonism-inducing neurotoxin MPTP and its metabolite MPP+ on sympathetic adrenergic nerves in mouse iris and atrium.
    Medical biology, 1986, Volume: 64, Issue:2-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adrenergic Fibers; Animals; Biological Transport, Active; Desipramine; Heart; Iris; Male; Mice; Nerve Degeneration; Norepinephrine; Pargyline; Pyridines; Pyridinium Compounds

1986
Catecholamine transporters and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: studies comparing the cloned human noradrenaline and human dopamine transporter.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Binding, Competitive; Carrier Proteins; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; Desipramine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Symporters

1996
LLC-PK(1) cells stably expressing the human norepinephrine transporter: A functional model of carrier-mediated norepinephrine release in protracted myocardial ischemia.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Biological Transport, Active; Desipramine; Drug Interactions; Gramicidin; Humans; Imidazoline Receptors; LLC-PK1 Cells; Mazindol; Models, Biological; Myocardial Ischemia; Nigericin; Norepinephrine; Receptors, Drug; Sodium; Swine; Time Factors

1999
Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: comparison with 5-hydroxytryptamine.
    Placenta, 2003, Volume: 24, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Carrier Proteins; Cell Line, Tumor; Choriocarcinoma; Desipramine; Dose-Response Relationship, Drug; Female; Fluoxetine; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Placenta; Quinolinium Compounds; Serotonin; Serotonin Plasma Membrane Transport Proteins; Uterine Neoplasms

2003
1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3.
    Journal of neurochemistry, 2003, Volume: 85, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents; Biological Transport; Cell Survival; Cells, Cultured; Cerebellum; Corticosterone; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Female; Male; Neurons; Neuroprotective Agents; Organic Cation Transport Proteins; Piperazines; Quinolines; Rats; RNA, Messenger; Rotenone; Temperature

2003
Protection against cell death and sustained tyrosine hydroxylase phosphorylation in hydrogen peroxide- and MPP-treated human neuroblastoma cells with melatonin.
    Journal of pineal research, 2009, Volume: 46, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Blotting, Western; Cell Death; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Desipramine; Humans; Hydrogen Peroxide; Melatonin; Neuroblastoma; Phosphorylation; Tyrosine 3-Monooxygenase

2009