desethylprocainamide has been researched along with acecainide in 4 studies
*Acecainide: A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure. [MeSH]
*Acecainide: A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure. [MeSH]
| Studies (desethylprocainamide) | Trials (desethylprocainamide) | Recent Studies (post-2010) (desethylprocainamide) | Studies (acecainide) | Trials (acecainide) | Recent Studies (post-2010) (acecainide) |
|---|---|---|---|---|---|
| 5 | 0 | 1 | 286 | 16 | 15 |
| Protein | Taxonomy | desethylprocainamide (IC50) | acecainide (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | 8.8 | |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boudoulas, H; Coyle, JD; Lima, JJ | 1 |
| Boudoulas, H; Coyle, JD; Lima, JJ; MacKichan, JJ | 1 |
| Gill, EW; Jones, A; Sim, E; Stanley, L | 1 |
| Atkinson, AJ; Henthorn, T; Morita, Y; Ruo, TI; Thenot, JP | 1 |
4 other study(ies) available for desethylprocainamide and acecainide
| Article | Year |
|---|---|
Acecainide pharmacokinetics in normal subjects of known acetylator phenotype.
Topics: Acecainide; Acetylation; Adult; Humans; Male; Phenotype; Procainamide | 1991 |
Reversed-phase liquid chromatography method for measurement of procainamide and three metabolites in serum and urine: percent of dose excreted as deethyl metabolites.
Topics: Acecainide; Chromatography, High Pressure Liquid; Humans; Kinetics; Procainamide; Quality Control | 1987 |
Metabolites of procainamide and practolol inhibit complement components C3 and C4.
Topics: Acecainide; Complement C3; Complement C4; Humans; Practolol; Procainamide; Protein Binding | 1988 |
Identification of desethyl procainamide in patients: a new metabolite of procainamide.
Topics: Acecainide; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Humans; Metabolic Clearance Rate; Mice; Procainamide; Respiration; Structure-Activity Relationship | 1981 |