Page last updated: 2024-08-26

desethylchloroquine and hydroxychloroquine

desethylchloroquine has been researched along with hydroxychloroquine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's6 (42.86)18.2507
2000's3 (21.43)29.6817
2010's2 (14.29)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Iredale, J; Wainer, IW1
Khalil, SK; Miller, DR; Nygard, GA1
Benziger, DP; Brown, RR; Stroshane, RM1
Croes, K; Flanagan, RJ; McCarthy, PT1
Fieger, H; Iredale, J; Wainer, IW2
Cutler, DJ; McLachlan, AJ; Tett, SE1
Baethge, BA; Botstein, GR; Caldwell, J; Dietz, F; Ettlinger, R; Furst, DE; Gibbs, JP; Golden, HE; Lindsley, H; McLaughlin, GE; Moreland, LW; Munster, T; Roberts, WN; Rooney, TW; Rothschild, B; Sack, M; Sebba, AI; Shen, D; Weisman, M; Welch, KE; Yocum, D1
Moraes de Oliveira, AR; Sueli Bonato, P1
Amoura, Z; Aymard, G; Costedoat-Chalumeau, N; Francès, C; Hulot, JS; Lechat, P; Leroux, G; Piette, JC1
Charlier, B; Dal Piaz, F; Fasano, S; Filippelli, A; Iudici, M; Izzo, V; Pantano, I; Pierro, L; Pingeon, M1
Amoura, Z; Combarel, D; Funck-Brentano, C; Lori, L; Noé, G; Seycha, A; Tissot, N; Zahr, N1
Ge, W; Luo, X; Peng, Y1
Baud, FJ; Clemessy, JL; Hoglund, RM; Megarbane, B; Tarning, J; Watson, JA; White, NJ1

Other Studies

14 other study(ies) available for desethylchloroquine and hydroxychloroquine

ArticleYear
Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography.
    Journal of chromatography, 1992, Jan-17, Volume: 573, Issue:2

    Topics: Animals; Biological Availability; Chloroquine; Chromatography, High Pressure Liquid; Hydroxychloroquine; Male; Rabbits; Spectrophotometry, Ultraviolet; Stereoisomerism

1992
Steady-state pharmacokinetics of hydroxychloroquine in rheumatoid arthritis patients.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:12

    Topics: Administration, Oral; Arthritis, Rheumatoid; Chloroquine; Female; Half-Life; Humans; Hydroxychloroquine; Male

1991
High-performance liquid chromatographic assay for hydroxychloroquine and three of its major metabolites, desethylhydroxychloroquine, desethylchloroquine and bidesethylchloroquine, in human plasma.
    Journal of chromatography, 1986, Apr-25, Volume: 377

    Topics: Chloroquine; Chromatography, High Pressure Liquid; Freezing; Humans; Hydroxychloroquine

1986
Simple and rapid HPLC of quinine, hydroxychloroquine, chloroquine, and desethylchloroquine in serum, whole blood, and filter paper-adsorbed dry blood.
    Journal of analytical toxicology, 1994, Volume: 18, Issue:5

    Topics: Adsorption; Chloroquine; Chromatography, High Pressure Liquid; Humans; Hydroxychloroquine; Quinine; Sensitivity and Specificity; Specimen Handling

1994
Determination of the stereoisomers of hydroxychloroquine and its major metabolites in plasma and urine following a single oral administration of racemic hydroxychloroquine.
    Seminars in arthritis and rheumatism, 1993, Volume: 23, Issue:2 Suppl 1

    Topics: Chloroquine; Humans; Hydroxychloroquine; Male; Stereoisomerism; Time Factors

1993
Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(-)-hydroxychloroquine ratio.
    Chirality, 1993, Volume: 5, Issue:2

    Topics: Chloroquine; Chromatography, High Pressure Liquid; Humans; Hydroxychloroquine; Stereoisomerism

1993
Plasma protein binding of the enantiomers of hydroxychloroquine and metabolites.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:5

    Topics: Blood Proteins; Chloroquine; Humans; Hydroxychloroquine; Protein Binding; Stereoisomerism

1993
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:6

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Eye Diseases; Gastrointestinal Diseases; Humans; Hydroxychloroquine; Logistic Models; Multicenter Studies as Topic; Oxidation-Reduction; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index

2002
Stereoselective determination of hydroxychloro-quine and its major metabolites in human urine by solid-phase microextraction and HPLC.
    Journal of separation science, 2007, Volume: 30, Issue:15

    Topics: Calibration; Chemistry Techniques, Analytical; Chloroquine; Chromatography; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hydroxychloroquine; Methanol; Models, Chemical; Reproducibility of Results; Solid Phase Extraction; Stereoisomerism; Temperature; Time Factors

2007
Relationship between blood hydroxychloroquine and desethylchloroquine concentrations and cigarette smoking in treated patients with connective tissue diseases.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:11

    Topics: Adult; Antirheumatic Agents; Chloroquine; Connective Tissue Diseases; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Smoking

2007
Health status and concomitant prescription of immunosuppressants are risk factors for hydroxychloroquine non-adherence in systemic lupus patients with prolonged inactive disease.
    Lupus, 2018, Volume: 27, Issue:2

    Topics: Adult; Antirheumatic Agents; Chloroquine; Female; Health Status; Humans; Hydroxychloroquine; Immunosuppressive Agents; Italy; Lupus Erythematosus, Systemic; Male; Middle Aged; Patient Reported Outcome Measures; Quality of Life; Risk Factors; Self-Assessment; Severity of Illness Index; Treatment Adherence and Compliance

2018
Development and Validation of a Fast Ultra-High Performance Liquid Chromatography-Fluorescent Method for the Quantification of Hydroxychloroquine and Its Metabolites in Patients With Lupus.
    Therapeutic drug monitoring, 2019, Volume: 41, Issue:4

    Topics: Antirheumatic Agents; Calibration; Chloroquine; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence; Humans; Hydroxychloroquine; Indicators and Reagents; Lupus Erythematosus, Systemic; Reproducibility of Results

2019
A Sensitive and Optimized HPLC-FLD Method for the Simultaneous Quantification of Hydroxychloroquine and Its Two Metabolites in Blood of Systemic Lupus Erythematosus Patients.
    Journal of chromatographic science, 2020, Jul-24, Volume: 58, Issue:7

    Topics: Adult; Chloroquine; Chromatography, High Pressure Liquid; Female; Humans; Hydroxychloroquine; Linear Models; Lupus Erythematosus, Systemic; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Young Adult

2020
Concentration-dependent mortality of chloroquine in overdose.
    eLife, 2020, 07-08, Volume: 9

    Topics: Adult; Antimalarials; Biotransformation; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Dose-Response Relationship, Drug; Drug Overdose; Drug Repositioning; Electrocardiography; Female; Heart Diseases; Humans; Hydroxychloroquine; Long QT Syndrome; Malaria; Male; Pandemics; Pneumonia, Viral; Randomized Controlled Trials as Topic; Risk Assessment; Suicide; Suicide, Attempted

2020