Page last updated: 2024-08-23

desciclovir and acyclovir

desciclovir has been researched along with acyclovir in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199017 (77.27)18.7374
1990's4 (18.18)18.2507
2000's1 (4.55)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Domin, BA; Mahony, WB; Zimmerman, TP1
Chapman, SK; Conant, MA; De Souza, YG; Greenspan, D; Greenspan, JS; Hollander, H; Lennette, ET; Petersen, V1
Czochralska, B; Johansson, NG; Kusmierek, JT; Shugar, D1
Berk, L; Chamuleau, RA; De Man, RA; Den Ouden, J; Heijtink, RA; Reesink, HW; Schalm, SW; ten Kate, FJ1
Schalm, SW1
Esmann, V; Geil, JP; Mogensen, CE; Petersen, CM; Peterslund, NA1
Furman, PA1
Fiddian, AP; Karayiannis, P; Tedder, RS; Thomas, HC; Weller, IV1
Chamuleau, RA; de Man, RA; den Ouden, J; Heijtink, RA; Reesink, HW; Schalm, SW1
Gerald, L; Quinn, RP; Tadepalli, S1
Davis, LG; Krasny, HC; Liao, S; Lietman, PS; Petty, BG; Rocco, LE; Whitley, RJ1
Krasny, HC; Petty, BG1
Krasny, HC; Krenitsky, TA1
Grant, DM; Prentice, HG; Rees, PJ; Selby, P; Whiteman, PD1
Brigden, D; Whiteman, P1
Peterslund, NA1
Blake, S; Hickmott, E; Mbidde, EK; McElwain, TJ; Powles, RL; Selby, P; Stolle, K; Whiteman, PD1
Bye, A; Fowle, AS; Jeal, S; Land, G; Posner, J; Whiteman, PD1
Beauchamp, LM; de Miranda, P; Hall, WW; Krenitsky, TA; Schaeffer, HJ; Whiteman, PD1
Kristl, A; Tukker, JJ1
Kmetec, V; Kristl, A; Pecar, S1
Kristl, A1

Trials

5 trial(s) available for desciclovir and acyclovir

ArticleYear
Efficacy of desciclovir in the treatment of Epstein-Barr virus infection in oral hairy leukoplakia.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3, Issue:6

    Topics: Acyclovir; Adult; Antigens, Viral; Antiviral Agents; DNA, Viral; Double-Blind Method; Herpesvirus 4, Human; Humans; Immunohistochemistry; Leukoplakia, Oral; Male; Randomized Controlled Trials as Topic; Serologic Tests; Tumor Virus Infections

1990
Long-term follow-up of antiviral combination therapy in chronic hepatitis B.
    The American journal of medicine, 1988, Aug-29, Volume: 85, Issue:2A

    Topics: Acyclovir; Adult; Clinical Trials as Topic; Drug Therapy; Female; Follow-Up Studies; Hepatitis B; Hepatitis, Chronic; Humans; Interferon Type I; Male; Pilot Projects; Prodrugs; Random Allocation; Time Factors

1988
Treatment of chronic hepatitis B with a combination of acyclovir and human lymphoblastoid interferon.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7 Suppl 3

    Topics: Acyclovir; Adolescent; Adult; Aged; Combined Modality Therapy; Hepatitis B; Hepatitis B e Antigens; Hepatitis, Chronic; Humans; Interferon Type I; Middle Aged; Prodrugs

1988
[Antiviral combination therapy in chronic hepatitis B].
    Nederlands tijdschrift voor geneeskunde, 1987, Jul-11, Volume: 131, Issue:28

    Topics: Acyclovir; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis B e Antigens; Hepatitis, Chronic; Humans; Interferon Type I; Male

1987
The treatment of herpes zoster infections.
    Scandinavian journal of infectious diseases. Supplementum, 1985, Volume: 47

    Topics: Acyclovir; Administration, Oral; Clinical Trials as Topic; Double-Blind Method; Drug Resistance, Microbial; Herpes Zoster; Humans; Immune Tolerance; Injections, Intravenous

1985

Other Studies

17 other study(ies) available for desciclovir and acyclovir

ArticleYear
Desciclovir permeation of the human erythrocyte membrane by nonfacilitated diffusion.
    Biochemical pharmacology, 1991, Jun-21, Volume: 42, Issue:1

    Topics: Acyclovir; Adenine; Cell Membrane Permeability; Diffusion; Erythrocyte Membrane; Humans; Idoxuridine; Kinetics; Papaverine

1991
Preparative electrochemical reduction of 2-amino-6-chloropurine and synthesis of 6-deoxyacyclovir, a fluorescent substrate of xanthine oxidase and a prodrug of acyclovir.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1987, Volume: 41, Issue:10

    Topics: 2-Aminopurine; Acyclovir; Adenine; Animals; Antiviral Agents; Electrolysis; Guinea Pigs; Herpes Simplex; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Polarography; Prodrugs; Simplexvirus; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Viral Plaque Assay; Xanthine Oxidase

1987
Open study of 2-amino-9-(hydroxyethoxymethyl)-9H-purine (desciclovir) in the treatment of herpes zoster.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:5

    Topics: Acyclovir; Aged; Antiviral Agents; Food; Half-Life; Herpes Zoster; Humans; Kidney Function Tests; Middle Aged

1987
Chemotherapy of herpesvirus infections.
    Current eye research, 1987, Volume: 6, Issue:1

    Topics: Acyclovir; Ganciclovir; Herpes Simplex; Humans; Purine Nucleosides; Pyrimidine Nucleosides

1987
A pilot study of BW A515U (6-deoxyacyclovir) in chronic hepatitis B virus infection.
    Journal of hepatology, 1986, Volume: 3 Suppl 2

    Topics: Acyclovir; Adult; Antiviral Agents; Carrier State; DNA-Directed DNA Polymerase; DNA, Viral; Hepatitis B; Hepatitis B virus; Homosexuality; Humans; Male; Pilot Projects; Virus Replication

1986
Radioimmunoassay for desciclovir, 2-[(2-amino-9H-purin-9-yl)methoxy]ethanol, a prodrug for the antiviral acyclovir.
    Journal of immunoassay, 1987, Volume: 8, Issue:2-3

    Topics: Acyclovir; Animals; Chromatography, Gas; Cross Reactions; Humans; Immune Sera; Rabbits; Radioimmunoassay; Reference Standards

1987
Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:9

    Topics: Acyclovir; Administration, Oral; Adult; Drug Administration Schedule; Drug Tolerance; Humans; Pharmacokinetics; Prodrugs

1987
Metabolism of desciclovir, a prodrug of acyclovir, in humans after multiple oral dosing.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:1

    Topics: Acyclovir; Administration, Oral; Adult; Biotransformation; Chromatography, High Pressure Liquid; Humans; Male; Middle Aged; Pharmaceutical Preparations; Prodrugs

1987
Allopurinol as an inhibitor of the in vivo formation of acyclovir from desciclovir.
    Biochemical pharmacology, 1986, Dec-01, Volume: 35, Issue:23

    Topics: Acyclovir; Allopurinol; Animals; Antiviral Agents; Male; Rats

1986
A515U: a prodrug of acyclovir with increased oral bioavailability.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl B

    Topics: Acyclovir; Administration, Oral; Biological Availability; Herpes Simplex; Humans; Intestinal Absorption; Metabolic Clearance Rate

1986
The clinical pharmacology of acyclovir and its prodrugs.
    Scandinavian journal of infectious diseases. Supplementum, 1985, Volume: 47

    Topics: Absorption; Acyclovir; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Digestive System; Half-Life; Humans; Infant; Infant, Newborn; Kidney; Kinetics

1985
Amino (hydroxyethoxymethyl) purine: a new well-absorbed prodrug of acyclovir.
    Lancet (London, England), 1984, Dec-22, Volume: 2, Issue:8417-8418

    Topics: Acyclovir; Administration, Oral; Adult; Drug Evaluation; Female; Humans; Kinetics; Male; Middle Aged

1984
Tolerance and pharmacokinetics of A515U, an acyclovir analogue, in healthy volunteers.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:4

    Topics: Absorption; Acyclovir; Adult; Biotransformation; Blood Pressure; Drug Tolerance; Female; Humans; Kinetics; Male; Middle Aged; Models, Biological; Pulse

1984
6-Deoxyacyclovir: a xanthine oxidase-activated prodrug of acyclovir.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:10

    Topics: Acyclovir; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Animals; Antiviral Agents; Biotransformation; Cattle; Chromatography, High Pressure Liquid; Female; Kinetics; Liver; Magnetic Resonance Spectroscopy; Milk; Oxidation-Reduction; Rabbits; Spectrophotometry, Ultraviolet; Xanthine Oxidase

1984
Negative correlation of n-octanol/water partition coefficient and transport of some guanine derivatives through rat jejunum in vitro.
    Pharmaceutical research, 1998, Volume: 15, Issue:3

    Topics: 1-Octanol; Acyclovir; Animals; Antiviral Agents; Biological Transport; Diffusion; In Vitro Techniques; Jejunum; Prodrugs; Rats; Rats, Wistar; Water

1998
Are calculated log P values for some guanine derivatives by different computer programs reliable?
    International journal of pharmaceutics, 1999, Apr-30, Volume: 181, Issue:2

    Topics: 1-Octanol; Acetylation; Acyclovir; Antiviral Agents; Chemistry, Pharmaceutical; Guanine; Kinetics; Linear Models; Software; Solubility; Water

1999
Comparative permeability of some acyclovir derivatives through native mucus and crude mucin dispersions.
    Drug development and industrial pharmacy, 2001, Volume: 27, Issue:7

    Topics: Acyclovir; Algorithms; Animals; Antiviral Agents; Biological Availability; Chromatography, High Pressure Liquid; Diffusion; Fluorescein; Guanine; In Vitro Techniques; Models, Biological; Mucins; Mucus; Permeability; Rats; Swine

2001