Page last updated: 2024-09-03

des-enkephalin-gamma-endorphin and morphine

des-enkephalin-gamma-endorphin has been researched along with morphine in 3 studies

Compound Research Comparison

Studies
(des-enkephalin-gamma-endorphin)
Trials
(des-enkephalin-gamma-endorphin)
Recent Studies (post-2010)
(des-enkephalin-gamma-endorphin)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
416044,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomydes-enkephalin-gamma-endorphin (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Capasso, A; Loizzo, A2
Capasso, A1

Other Studies

3 other study(ies) available for des-enkephalin-gamma-endorphin and morphine

ArticleYear
Guinea-pigs treated with beta-endorphin fragments DTgammaE and DEgammaE exhibit reduced morphine inhibition of electrically-induced contractions.
    Progress in neuro-psychopharmacology & biological psychiatry, 2000, Volume: 24, Issue:1

    Topics: Analgesics, Opioid; Animals; beta-Endorphin; Electric Stimulation; Endorphins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Narcotic Antagonists; Peptide Fragments; Time Factors

2000
Beta-endorphin fragments (DT gamma E and DE gamma E) reduce opiate withdrawal in guinea pig ileum.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:2

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Guinea Pigs; Ileum; Male; Morphine; Muscle Contraction; Opioid-Related Disorders; Peptide Fragments; Substance Withdrawal Syndrome

2002
Beta-endorphin fragments DTgammaE and DEgammaE reduced morphine inhibition of electrically-induced contractions and opiate withdrawal.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2009, Volume: 5, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Animals; beta-Endorphin; Electric Stimulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Ileum; In Vitro Techniques; Jejunum; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Oligopeptides; Peptide Fragments; Rabbits; Substance Withdrawal Syndrome

2009