Page last updated: 2024-09-03

des-enkephalin-gamma-endorphin and beta-endorphin

des-enkephalin-gamma-endorphin has been researched along with beta-endorphin in 36 studies

Compound Research Comparison

Studies
(des-enkephalin-gamma-endorphin)
Trials
(des-enkephalin-gamma-endorphin)
Recent Studies (post-2010)
(des-enkephalin-gamma-endorphin)
Studies
(beta-endorphin)
Trials
(beta-endorphin)
Recent Studies (post-2010) (beta-endorphin)
41606,480409444

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199024 (66.67)18.7374
1990's9 (25.00)18.2507
2000's3 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jackson, HC; Nutt, DJ; Ramsay, E1
Stegehuis, DS; Tjaden, UR; van den Beld, CM; van der Greef, J1
Elands, J; Kiraly, I; van Ree, JM; Wolterink, G2
Bijl, WA; Brendel, K; Davis, TP; Li, ZW; van Nispen, JW1
Stegehuis, DS; Tjaden, UR; van der Greef, J1
Azorin, JM; Blum, A; Charbaut, J; Escande, M; Granier, F; Huber, JP; Metzger, JY; Richou, H; Sitsen, A; Van Amerongen, P1
Andringa-Bakker, EA; de Rotte, AA; de Wied, D; van de Buuse, M; van Wimersma Greidanus, TB1
Kay, N; Morley, JE; van Ree, JM1
Breimer, DD; de Boer, AG; Heijligers-Feijen, CD; van Hoogdalem, EJ; Verhoef, JC1
De Boer, T; Ronken, E; Tonnaer, JA; Wiegant, VM1
Bodde, HE; Ponec, M; Verhoef, JC1
Costall, B; Domeney, AM; Naylor, RJ1
De Boer, T; Room, P; Tielemans, AJ; Tonnaer, JA1
Horn, AS; Radhakishun, FS; Van Ree, JM1
Radhakishun, FS; van Ree, JM; Westerink, BH1
Mulder, AH; Radhakishun, FS; Stoof, JC; van Ree, JM; Versteeg, DH1
van Ree, JM; Verhoeven, WM; Westenberg, HG1
Radhakishun, FS; Van Ree, JM1
van den Wildenberg, HM; Verhoef, JC1
De Wied, D; Drago, F; Van Ree, JM1
De Wied, D; Van Praag, HM; Van Ree, JM; Verhoeven, WM3
de Jongh, BM; de Wied, D; van Ree, JM; van Rood, JJ; Verhoeven, WM1
Király, I; Van Ree, JM1
Codd, EE; Scholtens, H; Van Ree, JM; Verhoef, JC; Witter, A; Wolterink, G1
de Wied, D; Heezius-van Bentum, A; van Praag, HM; van Ree, JM; Verhoeven, WM1
De Kloet, ER; Kovács, GL; Szabó, G; Versteeg, DH1
De Wied, D; Gaffori, O1
Radhakishun, FS; Stoof, JC; van Ree, JM; Westerink, BH; Wolterink, G1
Di Giannuario, A; Loizzo, A; Luzi, M; Pieretti, S1
Bruning, HW; de Boer, T; Kaspersen, FM; Ronken, E; Rust, CJ; Tonnaer, JA; van Nispen, JW; Wiegant, VM1
Capasso, A; Loizzo, A2
Capasso, A1

Trials

5 trial(s) available for des-enkephalin-gamma-endorphin and beta-endorphin

ArticleYear
Des-enkephalin-gamma-endorphin in the treatment of schizophrenia.
    International clinical psychopharmacology, 1990, Volume: 5, Issue:3

    Topics: Adult; beta-Endorphin; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1990
A comparative study on the antipsychotic properties of desenkephalin-gamma-endorphin and ceruletide in schizophrenic patients.
    Acta psychiatrica Scandinavica, 1986, Volume: 73, Issue:4

    Topics: Adult; beta-Endorphin; Ceruletide; Clinical Trials as Topic; Double-Blind Method; Endorphins; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Schizophrenia

1986
The treatment of schizophrenic psychoses with gamma-type endorphins.
    Biological psychiatry, 1982, Volume: 17, Issue:1

    Topics: beta-Endorphin; Brain; Clinical Trials as Topic; Dopamine; Double-Blind Method; Endorphins; gamma-Endorphin; Humans; Peptide Fragments; Psychotic Disorders; Receptors, Dopamine; Schizophrenia; Schizophrenic Psychology

1982
The use of the synthetic peptides gamma-type endorphins in mentally ill patients.
    Annals of the New York Academy of Sciences, 1982, Volume: 398

    Topics: Adult; beta-Endorphin; Brain; Clinical Trials as Topic; Dopamine; Double-Blind Method; Endorphins; Female; gamma-Endorphin; Humans; Male; Middle Aged; Peptide Fragments; Schizophrenia

1982
Antipsychotic properties of Des-enkephalin-gamma-endorphin in treatment of schizophrenic patients.
    Archives of general psychiatry, 1982, Volume: 39, Issue:6

    Topics: Adult; beta-Endorphin; Delusions; Double-Blind Method; Endorphins; Female; Hallucinations; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; Thinking

1982

Other Studies

31 other study(ies) available for des-enkephalin-gamma-endorphin and beta-endorphin

ArticleYear
Attenuation of the behavioural effects of ethanol in mice by des-enkephalin-gamma-endorphin (ORG 5878).
    Alcohol and alcoholism (Oxford, Oxfordshire), 1992, Volume: 27, Issue:4

    Topics: Animals; Arousal; beta-Endorphin; Body Temperature Regulation; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Motor Activity; Sensory Thresholds

1992
Bioanalysis of the neuropeptide des-enkephalin-gamma-endorphin by high-performance liquid chromatography with on-line sample pretreatment using gel permeation and solid-phase isolation.
    Journal of chromatography, 1991, Jul-19, Volume: 549, Issue:1-2

    Topics: beta-Endorphin; Chromatography, Gel; Chromatography, High Pressure Liquid; Drug Stability; Humans

1991
Gamma-type endorphins and brain dopaminergic systems.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; beta-Endorphin; Brain; Caudate Nucleus; Cerebral Cortex; Dopamine; Nucleus Accumbens; Rats; Receptors, Dopamine

1990
Neuropeptide processing in regional brain slices: effect of conformation and sequence.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:2

    Topics: Amino Acid Sequence; Animals; beta-Endorphin; Brain; Endopeptidases; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Molecular Sequence Data; Peptide Fragments; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tritium

1990
Bioanalysis of the peptide des-enkephalin-gamma-endorphin. On-line sample pretreatment using membrane dialysis and solid-phase isolation.
    Journal of chromatography, 1990, Jul-06, Volume: 511

    Topics: Acetonitriles; beta-Endorphin; Blood Proteins; Buffers; Dialysis; Humans; Hydrogen-Ion Concentration; Molecular Weight; Phosphates; Spectrometry, Fluorescence; Trichloroacetic Acid

1990
The effect of gamma-type endorphins on alpha-MSH release in the rat.
    Life sciences, 1985, Jul-22, Volume: 37, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; gamma-Endorphin; Haloperidol; Injections, Intraventricular; Male; Melanocyte-Stimulating Hormones; Naloxone; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains

1985
Enhancement of human lymphocyte natural killing function by non-opioid fragments of beta-endorphin.
    Life sciences, 1987, Mar-16, Volume: 40, Issue:11

    Topics: beta-Endorphin; Endorphins; gamma-Endorphin; Humans; Killer Cells, Natural; Naloxone; Peptide Fragments

1987
Rectal absorption enhancement of des-enkephalin-gamma-endorphin (DE gamma E) by medium-chain glycerides and EDTA in conscious rats.
    Pharmaceutical research, 1989, Volume: 6, Issue:1

    Topics: Absorption; Animals; beta-Endorphin; Edetic Acid; Glycerides; Male; Rats; Rats, Inbred Strains; Rectum

1989
Autoradiographic evidence for binding sites for des-enkephalin-gamma-endorphin (ORG 5878) in rat forebrain.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: Animals; Autoradiography; beta-Endorphin; Binding Sites; Brain; Male; Rats; Rats, Inbred Strains; Sulfur Radioisotopes

1989
Transdermal peptide delivery.
    Biochemical Society transactions, 1989, Volume: 17, Issue:5

    Topics: Administration, Cutaneous; beta-Endorphin; Half-Life; Humans; Peptides; Skin

1989
Antipsychotic substances and dopamine in the rat brain; behavioral studies reveal distinct dopamine receptor systems.
    European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; beta-Endorphin; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Injections; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Sulpiride

1989
Desenkephalin-gamma-endorphin is an antagonist of the hyperactivity response induced by infusion of dopamine into the nucleus accumbens of rat and ventral striatum of marmoset.
    Neuropharmacology, 1989, Volume: 28, Issue:11

    Topics: Animals; Apomorphine; beta-Endorphin; Callitrichinae; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Female; Fluphenazine; Haloperidol; Injections; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei

1989
The neuropeptide, Org 5878 (desenkephalin-gamma-endorphin, DE gamma E), affects local cerebral glucose utilization in freely moving rats.
    European journal of pharmacology, 1989, Nov-14, Volume: 171, Issue:1

    Topics: Animals; Antipsychotic Agents; Autoradiography; beta-Endorphin; Brain Chemistry; Cerebellum; Deoxyglucose; Glucose; Limbic System; Male; Rats; Rats, Inbred Strains; Tegmentum Mesencephali; Thalamus

1989
Desenkephalin-gamma-endorphin and neuroleptics counteract the DP-7-ATN-induced hypomotility after intra-accumbens treatment.
    European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1

    Topics: Animals; Antipsychotic Agents; beta-Endorphin; Haloperidol; Injections; Male; Motor Activity; Naphthalenes; Nucleus Accumbens; Rats; Rats, Inbred Strains; Sulpiride; Tetrahydronaphthalenes

1988
Dopamine release in the nucleus accumbens of freely moving rats determined by on-line dialysis: effects of apomorphine and the neuroleptic-like peptide desenkephalin-gamma-endorphin.
    Neuroscience letters, 1988, Jul-08, Volume: 89, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; beta-Endorphin; Computers; Dialysis; Dopamine; Male; Motor Activity; Nucleus Accumbens; Peptides; Rats; Rats, Inbred Strains; Septal Nuclei

1988
The neuroleptic-like peptide desenkephalin-gamma-endorphin does not antagonize the dopamine receptor agonist-induced inhibition of the release of [3H]dopamine from rat nucleus accumbens slices in vitro.
    Brain research, 1987, Nov-24, Volume: 426, Issue:2

    Topics: Animals; Apomorphine; beta-Endorphin; Dopamine; Ergolines; In Vitro Techniques; Male; Nucleus Accumbens; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Septal Nuclei; Tritium

1987
The hypomotility elicited by small doses of apomorphine seems exclusively mediated by dopaminergic systems in the nucleus accumbens.
    European journal of pharmacology, 1987, May-07, Volume: 137, Issue:1

    Topics: Analysis of Variance; Animals; Apomorphine; beta-Endorphin; Endorphins; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Septal Nuclei; Stereotyped Behavior; Sulpiride

1987
Des-enkephalin-gamma-endorphin: bioavailability in rats following the subcutaneous and intramuscular route of administration.
    Regulatory peptides, 1986, Volume: 14, Issue:2

    Topics: Animals; beta-Endorphin; Biological Availability; Chromatography, High Pressure Liquid; Endorphins; Half-Life; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Strains

1986
Desenkephalin-gamma-endorphin restores the impaired sensitivity of hypophysectomized rats to small doses of apomorphine.
    European journal of pharmacology, 1986, Sep-09, Volume: 128, Issue:3

    Topics: Animals; Apomorphine; beta-Endorphin; Endorphins; Hypophysectomy; Male; Motor Activity; Prolactin; Rats; Rats, Inbred Strains; Stereotyped Behavior

1986
Neuroleptic-like and antipsychotic effects of gamma-type endorphins.
    Modern problems of pharmacopsychiatry, 1981, Volume: 17

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; beta-Endorphin; Dopamine; Double-Blind Method; Endorphins; gamma-Endorphin; Humans; Peptide Fragments; Psychiatric Status Rating Scales; Psychotic Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Schizophrenia; Schizophrenic Psychology

1981
Hla, and the response to treatment with gamma-type endorphins in schizophrenia.
    Journal of immunogenetics, 1982, Volume: 9, Issue:6

    Topics: beta-Endorphin; Endorphins; gamma-Endorphin; HLA Antigens; HLA-B Antigens; HLA-B15 Antigen; HLA-C Antigens; Humans; Peptide Fragments; Schizophrenia

1982
Non-opiate beta-endorphin fragments and dopamine--VI. Behavioural analysis of the interaction between gamma-type endorphins and dopaminergic systems in the nucleus accumbens of rats.
    Neuropharmacology, 1984, Volume: 23, Issue:5

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; beta-Endorphin; Bromocriptine; Dopamine; Endorphins; Ergolines; Fluphenazine; gamma-Endorphin; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sulpiride

1984
In vivo interaction of gamma-type endorphins with dopaminergic ligands in rat brain.
    European journal of pharmacology, 1983, Apr-08, Volume: 88, Issue:4

    Topics: Animals; Apomorphine; beta-Endorphin; Brain; Endorphins; Motor Activity; Peptide Fragments; Rats; Receptors, Dopamine; Spiperone

1983
The effects of des-enkephalin-gamma-endorphin and des-Tyr1-a-endorphin on regional serotonin metabolism in rat brain.
    Brain research, 1982, Aug-12, Volume: 245, Issue:2

    Topics: Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Brain; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Hippocampus; Hypothalamus, Middle; Male; Mesencephalon; Peptide Fragments; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin

1982
Effect of des-Tyr1-gamma-endorphin and des-enkephalin-gamma-endorphin on active and passive avoidance behavior of rats; a dose-response relationship study.
    European journal of pharmacology, 1982, Nov-05, Volume: 85, Issue:1

    Topics: Animals; Avoidance Learning; Behavior, Animal; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Male; Peptide Fragments; Rats; Rats, Inbred Strains

1982
Subchronic treatment with the neuroleptic-like peptide desenkephalin-gamma-endorphin may decrease dopaminergic neurotransmission in the nucleus accumbens of rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; beta-Endorphin; Depression, Chemical; Dopamine; Dopamine Agents; In Vitro Techniques; Injections; Injections, Subcutaneous; Male; Nucleus Accumbens; Rats; Rats, Wistar; Synaptic Transmission

1994
Subchronic treatment with fragments of beta-endorphin prevents electroencephalographic seizures and behavioral alterations induced by centrally administered beta-endorphin in the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2

    Topics: Animals; Behavior, Animal; beta-Endorphin; Electroencephalography; Endorphins; Haloperidol; Injections, Intraventricular; Male; Naloxone; Peptide Fragments; Rabbits; Seizures

1994
Topography and characteristics of specific binding sites for non-opioid gamma-type endorphins in the rat brain as studied by autoradiography with [35S]Met-desenkephalin-gamma-endorphin.
    Brain research, 1993, Jun-25, Volume: 615, Issue:1

    Topics: Amygdala; Animals; Antibodies, Monoclonal; Autoradiography; beta-Endorphin; Binding, Competitive; Brain; Chromatography, High Pressure Liquid; Densitometry; Endorphins; Male; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Opioid; Structure-Activity Relationship; Sulfur Radioisotopes

1993
Guinea-pigs treated with beta-endorphin fragments DTgammaE and DEgammaE exhibit reduced morphine inhibition of electrically-induced contractions.
    Progress in neuro-psychopharmacology & biological psychiatry, 2000, Volume: 24, Issue:1

    Topics: Analgesics, Opioid; Animals; beta-Endorphin; Electric Stimulation; Endorphins; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Narcotic Antagonists; Peptide Fragments; Time Factors

2000
Beta-endorphin fragments (DT gamma E and DE gamma E) reduce opiate withdrawal in guinea pig ileum.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:2

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Guinea Pigs; Ileum; Male; Morphine; Muscle Contraction; Opioid-Related Disorders; Peptide Fragments; Substance Withdrawal Syndrome

2002
Beta-endorphin fragments DTgammaE and DEgammaE reduced morphine inhibition of electrically-induced contractions and opiate withdrawal.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2009, Volume: 5, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Animals; beta-Endorphin; Electric Stimulation; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Ileum; In Vitro Techniques; Jejunum; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Oligopeptides; Peptide Fragments; Rabbits; Substance Withdrawal Syndrome

2009