dermorphin has been researched along with triethylamine* in 1 studies
1 other study(ies) available for dermorphin and triethylamine
| Article | Year |
|---|---|
Fmoc-amino acid chlorides in solid phase synthesis of opioid peptides.
Fmoc-amino acid chlorides were employed in the solid phase synthesis of the opioid peptides [Leu]enkephalin, [Leu]enkephalin amide, and dermorphin. The conventional polystyrene-based Merrifield resin or Wang's resin served as solid support. A binary salt of either triethylamine or diisopropylethylamine in the presence of 1-hydroxybenzotriazole or pivalic acid was used for acylation. The coupling rates were quite fast, being comparatively faster when 1-hydroxybenzotriazole was used along with triethylamine or diisopropylethylamine. The peptides obtained in good yields showed, after purification, biological and spectral properties identical with those of the natural peptides. Topics: Acylation; Amino Acid Sequence; Amino Acids; Chlorides; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Ethylamines; Fluorenes; Molecular Sequence Data; Oligopeptides; Opioid Peptides; Triazoles | 1992 |