Page last updated: 2024-09-03

dermorphin, arg(2)- and thiorphan

dermorphin, arg(2)- has been researched along with thiorphan in 1 studies

*Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms. [MeSH]

*Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms. [MeSH]

Compound Research Comparison

Studies
(dermorphin, arg(2)-)
Trials
(dermorphin, arg(2)-)
Recent Studies (post-2010)
(dermorphin, arg(2)-)
Studies
(thiorphan)
Trials
(thiorphan)
Recent Studies (post-2010) (thiorphan)
12016655082

Protein Interaction Comparison

ProteinTaxonomydermorphin, arg(2)- (IC50)thiorphan (IC50)
ThermolysinBacillus thermoproteolyticus9.5
NeprilysinRattus norvegicus (Norway rat)0.0058
NeprilysinOryctolagus cuniculus (rabbit)0.0085
NeprilysinHomo sapiens (human)0.0024
Angiotensin-converting enzyme Homo sapiens (human)0.2281
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.42
NeprilysinSus scrofa (pig)0.0062

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kisara, K; Sakurada, S; Sakurada, T; Sasaki, Y; Suzuki, K; Watanabe, H1

Other Studies

1 other study(ies) available for dermorphin, arg(2)- and thiorphan

ArticleYear
Different effects of peptidase inhibitors on dermorphin- and on [D-Arg2]dermorphin-induced antinociceptive activity.
    European journal of pharmacology, 1992, Jan-28, Volume: 211, Issue:1

    Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Captopril; Male; Mice; Mice, Inbred Strains; Oligopeptides; Opioid Peptides; Pain Measurement; Peptides; Thiorphan

1992