Page last updated: 2024-08-21

dequalinium chloride and ucl 1684

dequalinium chloride has been researched along with ucl 1684 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dunn, PM; Galanakis, D; Ganellin, CR; Jenkinson, DH; Rosa, JC1
Bhandari, K; Campos Rosa, J; Dunn, PM; Galanakis, D; Ganellin, CR; Jenkinson, DH; Piergentili, A1
Chen, JQ; Dunn, PM; Galanakis, D; Ganellin, CR; Jenkinson, DH1
Chen, JQ; Dunn, PM; Galanakis, D; Ganellin, CR; Gunasekera, D1
Dunn, PM; Fletcher, DI; Ganellin, CR; Jenkinson, DH; Piergentili, A1
Andres, C; Fiedler, T; Gentles, RG; Grant-Young, K; Harden, DG; Hu, S; Huang, Y; Knox, R; Lodge, N; Poss, MA; Weaver, CD1
Christophersen, P; Hougaard, C; Jensen, ML; Nielsen, EØ; Peters, D; Strøbaek, D; Sørensen, US; Teuber, L1

Other Studies

7 other study(ies) available for dequalinium chloride and ucl 1684

ArticleYear
Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel.
    Journal of medicinal chemistry, 1998, Jan-01, Volume: 41, Issue:1

    Topics: Alkanes; Animals; Apamin; Brain; Humans; Molecular Structure; Oocytes; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Quinolinium Compounds; Rats; Small-Conductance Calcium-Activated Potassium Channels; Structure-Activity Relationship; Xenopus laevis

1998
Synthesis, molecular modeling, and pharmacological testing of bis-quinolinium cyclophanes: potent, non-peptidic blockers of the apamin-sensitive Ca(2+)-activated K(+) channel.
    Journal of medicinal chemistry, 2000, Feb-10, Volume: 43, Issue:3

    Topics: Alkanes; Animals; Apamin; Cells, Cultured; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Quinolinium Compounds; Rats; Small-Conductance Calcium-Activated Potassium Channels; Structure-Activity Relationship; Superior Cervical Ganglion

2000
bis-Quinolinium cyclophanes: 8,14-diaza-1,7(1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin-sensitive Ca(2+)-activated K(+) channel.
    Journal of medicinal chemistry, 2000, Sep-21, Volume: 43, Issue:19

    Topics: Animals; Apamin; Calcium; Cells, Cultured; Neurons; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Quinolinium Compounds; Rats; Small-Conductance Calcium-Activated Potassium Channels; Structure-Activity Relationship

2000
Bis-quinolinium cyclophanes: toward a pharmacophore model for the blockade of apamin-sensitive SKCa channels in sympathetic neurons.
    Bioorganic & medicinal chemistry letters, 2004, Aug-16, Volume: 14, Issue:16

    Topics: Apamin; Calcium Channels; Models, Chemical; Molecular Structure; Neurons; Quinolines; Sympathetic Nervous System

2004
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)).
    Bioorganic & medicinal chemistry, 2007, Aug-15, Volume: 15, Issue:16

    Topics: Aminoquinolines; Animals; Apamin; Guanidine; Molecular Sequence Data; Molecular Structure; Neurons; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Structure-Activity Relationship; Tissue Culture Techniques

2007
Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels.
    Bioorganic & medicinal chemistry letters, 2008, Oct-01, Volume: 18, Issue:19

    Topics: Apamin; Combinatorial Chemistry Techniques; Molecular Structure; Potassium Channel Blockers; Pyridines; Small-Conductance Calcium-Activated Potassium Channels; Structure-Activity Relationship; Thiazoles

2008
Synthesis and structure-activity relationship studies of 2-(N-substituted)-aminobenzimidazoles as potent negative gating modulators ofsmall conductance Ca2+-activated K+ channels.
    Journal of medicinal chemistry, 2008, Dec-11, Volume: 51, Issue:23

    Topics: 1-Naphthylamine; Benzimidazoles; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; Molecular Structure; Small-Conductance Calcium-Activated Potassium Channels; Stereoisomerism; Structure-Activity Relationship

2008